The cheapest and fastest buses from Greenville, SC to New Orleans, LA
Cheapest price
$116
Average price
$139
Fastest journey
13 h 50 m
Average duration
16 h 53 m
Buses per day
2
Distance
903 km
The best way to find a cheap bus ticket from Greenville, SC to New Orleans, LA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to New Orleans, LA will cost around $139 if you buy it on the day, but the cheapest tickets can be found for only $116.
Of the 2 buses that leave Greenville, SC for New Orleans, LA on Tue, Mar 24, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Mar 24 the direct buses cover the 903 km distance in an average of 16 h 53 m but if you time it right, some buses will get you there in just 13 h 50 m .
On Tue, Mar 24 the slowest buses will take 19 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Greenville, SC to New Orleans, LA
Omio recommends booking the train as it is the most popular option from Greenville, SC to New Orleans, LA among Omio's users. If you are prioritising price take the bus with prices starting from $98. For those with little time consider booking a flight which can get you there in 6h 30m. The ticket price range depends on the travel mode: a bus costs an average of $98, and a flight costs an average of $127.
Distance: 561 miles (903 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$136 Average price Cheapest | $166 Average price | $278 Average price |
19h 29m Average total duration 18h 59m Onboard + 30m Additional time* | 17h 1m Average total duration 16h 31m Onboard + 30m Additional time* | 9h 30m Average total duration Fastest 6h 30m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Greenville, SC to New Orleans, LA bus times
The table below shows live departures for Greenville, SC to New Orleans, LA buses for tomorrow, Sunday, March 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:45 AM Greenville, SC | 13h50 | 2:35 PM New Orleans, LA | 0 transfersDirect | |
![]() | 3:00 AM Greenville, SC | 19h55 | 10:55 PM New Orleans, LA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to New Orleans, LA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 23
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Mar 29
Journey information
Overview: Bus from Greenville, SC to New Orleans, LA
Buses from Greenville, SC to New Orleans, LA run on average 4 times per day, taking around 18h 59m. Cheap bus tickets for this journey start at $98 (€79) if you book in advance.
The earliest bus runs at 05:10, the last at 23:35. The fastest bus covers the 561 miles (903 km) distance in 12h 59m.
Distance 561 miles (903 km) |
Average bus duration 18h 59m |
Cheapest ticket price $98 (€79) |
Buses per day 4 |
Fastest bus 12h 59m |
First bus 05:10 |
Last bus 23:35 |
Cheapest month Feb |
Cheapest day Tue |
High season Oct - Dec |
Low season Apr - Jun |
FAQs: Bus from Greenville, SC to New Orleans, LA
Find answers to the most common questions about traveling from Greenville, SC to New Orleans, LA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at New Orleans, LA, this guide helps you travel smarter and with confidence.

- French Quarter, a historic district known for its vibrant nightlife, colorful buildings, and rich cultural heritage
- Jackson Square, a historic park in the heart of the French Quarter surrounded by iconic landmarks and street performers
- St. Louis Cathedral, a stunning example of French Gothic architecture and the oldest continuously active Roman Catholic cathedral in the United States
- Garden District, a picturesque neighborhood famous for its well-preserved antebellum mansions and lush gardens
- National WWII Museum, an extensive museum offering immersive exhibits and artifacts detailing the American experience in World War II.
- Preservation Hall, enjoy traditional New Orleans jazz performances in an intimate and historic setting
- Audubon Park, relax in this beautiful urban park featuring walking paths, a zoo, and a golf course
- Frenchmen Street, experience the vibrant music scene with live performances in numerous bars and clubs
- Steamboat Natchez, take a scenic cruise along the Mississippi River on an authentic paddlewheel steamboat
- City Park, explore this expansive park with botanical gardens, an art museum, and outdoor activities.
popular bus stations
Popular bus stations from Greenville, SC to New Orleans, LA
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to New Orleans, LA
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