- Must visit
New Orleans Museum of Art
Leading art museum in City Park with major European, American, African, and contemporary collections plus a renowned sculpture garden.
Buses from Greenville, SC to New Orleans, LA run on average 3 times per day, taking around 14h 25m. Cheap bus tickets for this journey start at zł 254 if you book in advance.
The earliest bus runs at 05:10, the last at 23:35. The fastest bus covers the 561 miles (903 km) distance in 11h 45m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Greenville, SC to New Orleans, LA.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 10:31AM | Arrival Time 11:30PM | Duration 12h59 | Departure days Tue | Cheapest price zł 664 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 05:30AM | Duration 15h45 | Departure days Thu | Cheapest price zł 370 |
Operator Greyhound | Departure Time 02:50PM | Arrival Time 05:30AM | Duration 15h40 | Departure days Fri | Cheapest price zł 395 |
Operator Greyhound | Departure Time 08:20PM | Arrival Time 08:35AM | Duration 13h15 | Departure days Thu, Fri | Cheapest price zł 374 |
Operator Greyhound | Departure Time 09:35PM | Arrival Time 04:50PM | Duration 20h15 | Departure days Thu, Fri | Cheapest price zł 370 |
Operator Greyhound | Departure Time 11:40PM | Arrival Time 01:35PM | Duration 13h55 | Departure days Mon, Tue, Sat, Sun | Cheapest price zł 334 |
The table below shows live departures for Greenville, SC to New Orleans, LA buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:31 AM Greenville, SC | 12h59 | 11:30 PM New Orleans, LA | 0 transfersDirect | |
![]() | 11:40 PM Greenville, SC | 13h55 | 1:35 PM New Orleans, LA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Greenville, SC to New Orleans, LA with Greyhound. Overnight buses available on this route with Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of New Orleans, LA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect New Orleans, LA trip today.
Leading art museum in City Park with major European, American, African, and contemporary collections plus a renowned sculpture garden.
Powerful museum using immersive exhibits to explain World War II through personal stories, artifacts, and major military history.
Smithsonian-affiliated museum devoted to Southern art, design, and culture in a contemporary warehouse district setting.
The city’s most famous neighborhood, packed with historic architecture, music, courtyards, and essential New Orleans street life.
Lively public square facing St. Louis Cathedral, ideal for architecture, performers, and a classic introduction to the city.
Vast urban park with oak groves, lagoons, museums, and trails, offering one of the best green escapes in New Orleans.
A hearty Creole rice dish with sausage, chicken, and seafood. It reflects Spanish, French, and local influences central to New Orleans cooking.
A rich Louisiana stew usually made with roux, okra or filé, and seafood or sausage. It is a signature dish of Creole and Cajun tradition.
A classic po' boy is a French bread sandwich stuffed with fried shrimp, oysters, or roast beef. It is one of the city's most iconic everyday foods.
Celebrated Creole restaurant famous for gumbo z'herbes, turtle soup, and jazz brunch in an elegant Garden District mansion.
Casual landmark for classic po' boys and fried seafood. Expect a lively, old-school New Orleans atmosphere near the French Quarter.
Historic coffee stand best known for beignets and chicory café au lait. It is busy, informal, and one of the city's essential stops.
Moderate for U.S. cities: hotels can be pricey in peak season, but food and transit are reasonable for tourists.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and spare change or $1 at cafes for good service.
Official public transport app
Louis Armstrong New Orleans International Airport -> Canal Street, New Orleans, LA
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in New Orleans, LA.
Find answers to the most common questions about traveling from Greenville, SC to New Orleans, LA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at New Orleans, LA, this guide helps you travel smarter and with confidence.
