Greenville, SC to Pittsburgh, PA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05PM | Arrival Time 06:30AM | Duration 18h25 | Departure days Wed | Cheapest price $175 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 10:15AM | Duration 18h00 | Departure days Wed | Cheapest price $175 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 05:50PM | Duration 19h50 | Departure days Wed | Cheapest price $177 |
Journey information
Overview: Bus from Greenville, SC to Pittsburgh, PA
Take a bus from Greenville, SC to Pittsburgh, PA and enjoy the approximately 407 miles (656 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 01:35, the last at 23:10.
Distance 407 miles (656 km) |
Average bus duration 16h 5m |
Buses per day 4 |
First bus 01:35 |
Last bus 23:10 |
Bus providers: FlixBus from Greenville, SC to Pittsburgh, PAYou can travel by bus between Greenville, SC to Pittsburgh, PA with FlixBus. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Greenville, SC to Pittsburgh, PA
Find answers to the most common questions about traveling from Greenville, SC to Pittsburgh, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Pittsburgh, PA, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- The Andy Warhol Museum, a comprehensive collection dedicated to the life and works of the iconic pop artist
- Phipps Conservatory and Botanical Gardens, a historic greenhouse with diverse plant exhibits and sustainable architecture
- Carnegie Museum of Natural History, featuring extensive dinosaur displays and global cultural artifacts
- Point State Park, a scenic urban park at the confluence of three rivers with historical significance
- Mount Washington, offering panoramic views of Pittsburgh's skyline from its renowned overlooks.
- Heinz History Center, an affiliate of the Smithsonian Institution showcasing Western Pennsylvania's history and heritage
- Take a ride on the Duquesne Incline for a historic cable car experience and stunning city views
- Explore the Strip District, known for its vibrant markets, eateries, and unique shops
- Visit the National Aviary, home to a diverse collection of birds from around the world
- Enjoy a Pittsburgh Pirates game at PNC Park, renowned for its beautiful views of the city skyline.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Greenville, SC to Pittsburgh, PA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Greenville, SC to Pittsburgh, PA
Most popular bus connections from Greenville, SC
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