- Must visit
The Andy Warhol Museum
A vast contemporary art museum founded by Andy Warhol, featuring immersive exhibitions and the largest collection of his work and archives.
Cheapest price on Sep 19
$82
Average ticket price on Sep 19
$91
Fastest journey on Sep 19
18 h 40 m
Average journey duration on Sep 19
20 h 9 m
Buses on Sep 19
4
Distance
656 km
The best way to find a cheap bus ticket from Greenville, SC to Pittsburgh, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Pittsburgh, PA will cost around $91 if you buy it on the day, but the cheapest tickets can be found for only $82.
It's difficult to get from Greenville, SC to Pittsburgh, PA without transferring at least once.
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Omio recommends booking the bus as it is the most popular option from Greenville, SC to Pittsburgh, PA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $133 For those with little time, consider booking a flight, which has an average total journey time of 5h 57m. Average ticket prices depend on the travel mode: a bus costs an average of $133, while a flight costs an average of $644.
Distance: 407 miles (656 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$133 Average price Cheapest | $644 Average price | $237 Average price | $107 Average price (fuel + tolls) |
18h 20m Average total duration 17h 50m Onboard + 30m Additional time* | 5h 57m Average total duration Fastest 3h 57m Onboard + 2h 0m Additional time* | 19h 37m Average total duration 19h 7m Onboard + 30m Additional time* | 8h 11m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Pittsburgh, PA:
A bus is $104 less than a train for this route with tickets for a train from Greenville, SC to Pittsburgh, PA costing on average $237.
A bus is $511 less than a flight for this route with tickets for a flight from Greenville, SC to Pittsburgh, PA costing on average $644.
Other travel options to Pittsburgh, PA take longer:
Bus takes on average 17h 50m.
Train takes on average 19h 7m.
Tickets start at around $133 compared to roughly $107 in fuel and tolls — a saving of about $-26.27. The journey takes 17h 50m versus 8h 11m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 11:50PM | Duration 20h25 | Departure days Everyday | Cheapest price $97 |
Operator Greyhound | Departure Time 11:00AM | Arrival Time 07:35AM | Duration 20h35 | Departure days Tue, Wed | Cheapest price $75 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 07:35AM | Duration 18h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $82 |
Operator Greyhound | Departure Time 01:20PM | Arrival Time 05:40PM | Duration 28h20 | Departure days Tue, Wed | Cheapest price $77 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 01:30PM | Duration 21h15 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $85 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 05:50PM | Duration 20h15 | Departure days Everyday | Cheapest price $76 |
The table below shows live departures for Greenville, SC to Pittsburgh, PA buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 9:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 20h15 | 5:50 PM Pittsburgh, Greyhound Bus Station, PA | 1 transfer | |
| Saturday, September 19 | |||||
· | 3:25 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 20h25 | 11:50 PM Pittsburgh, Greyhound Bus Station, PA | 1 transfer | |
FlixBus+![]() | 12:55 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 18h40 | 7:35 AM Pittsburgh, Greyhound Bus Station, PA | 1 transfer | |
FlixBus+![]() | 4:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 21h15 | 1:30 PM Pittsburgh, Greyhound Bus Station, PA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, SC to Pittsburgh, PA run on average 4 times per day, taking around 17h 50m. Cheap bus tickets for this journey start at $86 if you book in advance.
The earliest bus runs at 01:30, the last at 23:10. The fastest bus covers the 407 miles (656 km) distance in 14h 40m.
Distance 407 miles (656 km) |
Average bus duration 17h 50m |
Cheapest ticket price $86 |
Buses per day 4 |
Fastest bus 14h 40m |
First bus 1:30 AM |
Last bus 11:10 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Discover the best of Pittsburgh, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Pittsburgh, PA trip today.
A vast contemporary art museum founded by Andy Warhol, featuring immersive exhibitions and the largest collection of his work and archives.
A major natural history museum with dinosaur halls, gems, and world cultures, ideal for understanding science and exploration in one landmark institution.
A respected fine arts museum with European masters, decorative arts, and rotating exhibitions in the historic Carnegie museum complex.
A riverfront state park at Pittsburgh's founding point, famous for the fountain, fort history, and sweeping views where three rivers meet.
A hillside observation terrace on Mount Washington delivering one of America's classic city panoramas, especially memorable at sunset or night.
A revitalized Strip District street lined with markets, shops, murals, and energy that captures the city's old warehouse district character.
A towering deli sandwich packed with grilled meat, coleslaw, tomatoes, and fries inside Italian bread. It became a Pittsburgh icon at Primanti Bros.
Soft Italian bread stuffed with seasoned potatoes and onions. Brought by Italian immigrants, it remains a beloved bakery staple around Pittsburgh.
Dough pockets usually filled with potato and cheese, then boiled or fried with onions. Pittsburgh celebrates them through strong Eastern European roots.
Beloved casual spot specializing in handmade pierogies with many fillings and toppings. A local favorite for classic Pittsburgh comfort food.
Acclaimed fine-dining destination in Lawrenceville with seasonal tasting menus, polished service, and one of the city’s strongest culinary reputations.
Long-running brewery and restaurant serving German and local beers, sausages, and hearty fare. Traditional atmosphere in a landmark North Side building.
Moderate for U.S. city breaks: hotels and dining are mid-priced, transit is affordable, and attractions are often cheaper than in New York or San Francisco.
Tip 18-20% at restaurants, about 10-15% for taxis, and $1-2 per drink or coffee in cafes if service is provided.
Find answers to the most common questions about traveling from Greenville, SC to Pittsburgh, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Pittsburgh, PA, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Pittsburgh, PA buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Pittsburgh, Greyhound Bus Station station pair. Use this guide to compare Greenville, SC and Pittsburgh, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Limited dining options available in adjacent areas.
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Pittsburgh, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bar available on site
Available throughout the station. ATMs are aTM located near the entrance.
Ticket office support is available at Pittsburgh, Greyhound Bus Station.
Available at Pittsburgh, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Pittsburgh, Greyhound Bus Station: Wheelchair accessible entrances.
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