- Must visit
Carnegie Museum Of Natural History
Major natural history museum known for its dinosaur halls, gemstones, and scientific collections. It is one of Pittsburgh’s classic cultural highlights.
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The cheapest and fastest buses from Greenville, SC to Pittsburgh, PA
Showing times and prices for Jun 21
Cheapest price
$137
Average price
$147
Fastest journey
18 h 35 m
Average duration
20 h 21 m
Buses per day
4
Distance
656 km
Cheap tickets
The best way to find a cheap bus ticket from Greenville, SC to Pittsburgh, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Pittsburgh, PA will cost around $147 if you buy it on the day, but the cheapest tickets can be found for only $137.
Fast buses
It's difficult to get from Greenville, SC to Pittsburgh, PA without transferring at least once.
· +
FlixBus7:10 AM23h05Greenville, Woodruff Rd ("Raceway" gas station), SC6:15 AMPittsburgh, Greyhound Bus Station, PA$1371One-way2 transfers- FlixBus+12:15 PM19h20Greenville, Woodruff Rd ("Raceway" gas station), SC7:35 AMPittsburgh, Greyhound Bus Station, PA$1491One-way1 transfer
- · 3:25 AM20h25Greenville, Woodruff Rd ("Raceway" gas station), SC11:50 PMPittsburgh, Greyhound Bus Station, PA$1501One-way1 transfer
- FlixBus+4:15 PM18h35Greenville, Woodruff Rd ("Raceway" gas station), SC10:50 AMPittsburgh, Greyhound Bus Station, PA$1531One-way1 transfer
- FlixBus+4:15 PM18h35Greenville, Woodruff Rd ("Raceway" gas station), SC10:50 AMPittsburgh, Greyhound Bus Station, PA$1531One-way1 transfer
- FlixBus+12:15 PM19h20Greenville, Woodruff Rd ("Raceway" gas station), SC7:35 AMPittsburgh, Greyhound Bus Station, PA$1491One-way1 transfer
- · 3:25 AM20h25Greenville, Woodruff Rd ("Raceway" gas station), SC11:50 PMPittsburgh, Greyhound Bus Station, PA$1501One-way1 transfer
- · +FlixBus7:10 AM23h05Greenville, Woodruff Rd ("Raceway" gas station), SC6:15 AMPittsburgh, Greyhound Bus Station, PA$1371One-way2 transfers
Travel Information
Compare bus and flight for Greenville, SC to Pittsburgh, PA
Omio recommends booking the bus as it is the most popular option from Greenville, SC to Pittsburgh, PA among Omio's users. If you are prioritising price take the bus with prices starting from $237. For those with little time consider booking a flight which can get you there in 4h 0m. The ticket price range depends on the travel mode: a bus costs an average of $237, and a flight costs an average of $372.
Distance: 407 miles (656 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$237 Average price Cheapest | $372 Average price | $105 Average price (fuel + tolls) |
16h 35m Average total duration 16h 5m Onboard + 30m Additional time* | 7h 0m Average total duration Fastest 4h 0m Onboard + 3h 0m Additional time* | 8h 11m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Greenville, SC to Pittsburgh, PA is a bus with an average price of $237 (€194).
This is compared to other travel options from Greenville, SC to Pittsburgh, PA:
A bus is $135 (€110) less than a flight for this route with tickets for a flight from Greenville, SC to Pittsburgh, PA costing on average $372 (€304).
The fastest way to travel from Greenville, SC to Pittsburgh, PA is by flight with an average journey time of 4h 0m.
Other travel options to Pittsburgh, PA take longer:
Bus takes on average 16h 5m.
It's helpful to compare your options as there are 2 ways to travel between Greenville, SC and Pittsburgh, PA including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Greenville, SC to Pittsburgh, PA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Greenville, SC to Pittsburgh, PA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:00AM | Arrival Time 10:50PM | Duration 19h50 | Departure days Thu | Cheapest price $237 |
Operator Greyhound | Departure Time 03:25AM | Arrival Time 11:50PM | Duration 20h25 | Departure days Mon, Thu, Sat, Sun | Cheapest price $133 |
Operator Greyhound | Departure Time 07:10AM | Arrival Time 06:15AM | Duration 23h05 | Departure days Mon, Sat, Sun | Cheapest price $137 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 07:35AM | Duration 19h20 | Departure days Mon, Thu, Sat, Sun | Cheapest price $107 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 10:50AM | Duration 18h35 | Departure days Mon, Thu, Sat, Sun | Cheapest price $133 |
Live departures
Greenville, SC to Pittsburgh, PA bus times
The table below shows live departures for Greenville, SC to Pittsburgh, PA buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · +FlixBus | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 23h05 | 6:15 AM Pittsburgh, Greyhound Bus Station, PA | 2 transfers | |
| FlixBus+ | 12:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 19h20 | 7:35 AM Pittsburgh, Greyhound Bus Station, PA | 1 transfer | |
| FlixBus+ | 4:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 18h35 | 10:50 AM Pittsburgh, Greyhound Bus Station, PA | 1 transfer | |
| Sunday, June 21 | |||||
| · | 3:25 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 20h25 | 11:50 PM Pittsburgh, Greyhound Bus Station, PA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to Pittsburgh, PA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Jun 21
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Why should you book Greenville, SC to Pittsburgh, PA buses with Omio?
FlixBus operates all buses services from Greenville, SC to Pittsburgh, PA.
Omio is an official ticket reseller for all your travel options from Greenville, SC to Pittsburgh, PA.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Greenville, SC to Pittsburgh, PA.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Greenville, SC to Pittsburgh, PA.
Journey information
Overview: Bus from Greenville, SC to Pittsburgh, PA
USAUSA
Buses from Greenville, SC to Pittsburgh, PA run on average 2 times per day, taking around 16h 5m. Cheap bus tickets for this journey start at $237 (€194) if you book in advance.
The earliest bus runs at 01:30, the last at 23:10. The fastest bus covers the 407 miles (656 km) distance in 19h 50m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 407 miles (656 km) |
Average bus duration 16h 5m |
Cheapest ticket price $237 (€194) |
Buses per day 2 |
Fastest bus 19h 50m |
First bus 1:30 AM |
Last bus 11:10 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Apr - Jun |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus from Greenville, SC to Pittsburgh, PAYou can travel by bus between Greenville, SC to Pittsburgh, PA with FlixBus for as low as $237 (€194). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
19h 50m
Cheapest Price
$237 (€194)
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Pittsburgh
Things to do in Pittsburgh
Discover the best of Pittsburgh — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Pittsburgh trip today.
- Must visit
Carnegie Museum Of Art
Renowned art museum with strong contemporary and historic collections. A top stop in Oakland for visitors interested in American and international art.
- Must visit
The Andy Warhol Museum
The largest museum in North America devoted to a single artist. It covers Andy Warhol’s life, films, paintings, and pop art legacy.
- Must visit
Mount Washington
Hilltop neighborhood famous for panoramic views over Downtown, the rivers, and bridges. It is one of the most essential places for first-time visitors.
- Must visit
Grandview Avenue
Scenic avenue along Mount Washington with classic overlook terraces. A top place for skyline photos, sunset views, and short walks.
- Must visit
Point State Park
Downtown riverfront park at the confluence of the Allegheny, Monongahela, and Ohio rivers. It is ideal for walking, relaxing, and iconic city views.
Primanti-Style Sandwich
A thick sandwich layered with grilled meat, coleslaw, tomato, and French fries inside Italian bread. It is one of Pittsburgh’s most iconic local foods.
- Vegetarian
Pierogies
Polish dumplings commonly filled with potato and cheese, sauerkraut, or meat. They reflect the city’s strong Eastern European immigrant heritage.
- Gluten-free
Pittsburgh Salad
A large salad topped with grilled meat, cheese, and French fries. It is a classic regional restaurant dish known for combining comfort food with salad greens.
Apteka Pittsburgh
A nationally recognized restaurant serving creative Eastern European dishes in a stylish, modern setting. Especially notable for vegetable-focused interpretations of regional flavors.
Legume Pittsburgh
A respected neighborhood restaurant known for seasonal American cooking, thoughtful plating, and a refined but approachable atmosphere.
Pamela's Diner Pittsburgh
A beloved local diner famous for thin crepe-style hotcakes and hearty breakfast plates. Relaxed and classic, it is a staple of Pittsburgh comfort food.
United States Dollar
Moderate for U.S. city travel. Hotels vary by season, while casual dining, coffee, and local transport are generally manageable for most visitors.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 20-35 per person at a casual restaurant.
- Fine dining
- USD 60+ per person at upscale restaurants.
- Coffee
- USD 3-6 for a regular coffee or latte.
Tipping culture
Tip 18-20% at restaurants, 20%+ for great service, USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and USD 1-2 per bag for hotel staff.
FAQs: Bus from Greenville, SC to Pittsburgh, PA
Find answers to the most common questions about traveling from Greenville, SC to Pittsburgh, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Pittsburgh, PA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Greenville, SC to Pittsburgh, PA can start from as little as $237 (€194) when you book in advance. The average bus ticket price for Greenville, SC to Pittsburgh, PA is $237 (€194) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Greenville, SC to Pittsburgh, PA is 19h 50m to travel the 407 miles (656 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Greenville, SC to Pittsburgh, PA leaves at 1:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Greenville, SC to Pittsburgh, PA leaves at 11:10 PM.
There are 2 buses a day from Greenville, SC to Pittsburgh, PA which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Greenville, SC to Pittsburgh, PA, you can count on FlixBus for the best way to get you to Pittsburgh, PA. You can also check all possible bus companies who offer a service between Greenville, SC and Pittsburgh, PA and compare the amenities they offer before buying a bus ticket.
A trip to Pittsburgh, PA from Greenville, SC is worth doing but not as a day trip with a journey time of 19h 50m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Greenville, SC to Pittsburgh, PA is September.
It's helpful to compare your options as there are 2 ways to travel between Greenville, SC and Pittsburgh, PA including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Greenville, SC to Pittsburgh, PA:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Greenville, SC to Pittsburgh, PA for bus company FlixBus.
Some of the most interesting sights to explore in Pittsburgh, PA are:
- The Andy Warhol Museum, a comprehensive collection dedicated to the life and works of the iconic pop artist
- Phipps Conservatory and Botanical Gardens, a historic greenhouse with diverse plant exhibits and sustainable architecture
- Carnegie Museum of Natural History, featuring extensive dinosaur displays and global cultural artifacts
- Point State Park, a scenic urban park at the confluence of three rivers with historical significance
- Mount Washington, offering panoramic views of Pittsburgh's skyline from its renowned overlooks.
The best things to do in Pittsburgh, PA include:
- Heinz History Center, an affiliate of the Smithsonian Institution showcasing Western Pennsylvania's history and heritage
- Take a ride on the Duquesne Incline for a historic cable car experience and stunning city views
- Explore the Strip District, known for its vibrant markets, eateries, and unique shops
- Visit the National Aviary, home to a diverse collection of birds from around the world
- Enjoy a Pittsburgh Pirates game at PNC Park, renowned for its beautiful views of the city skyline.
Whether you can cancel your bus ticket from Greenville, SC to Pittsburgh, PA depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Greenville, SC to Pittsburgh, PA.
Yes, the following luggage options are included when booking a bus ticket from Greenville, SC to Pittsburgh, PA:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Greenville, SC to Pittsburgh, PA:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Greenville, SC to Pittsburgh, PA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Greenville, SC to Pittsburgh, PA with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Greenville, SC to Pittsburgh, PA with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Greenville, SC to Pittsburgh, PA with the following bus company: FlixBus.
Since neither Greenville, SC nor Pittsburgh, PA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Greenville, SC to Pittsburgh, PA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Pittsburgh, PA, travelers should be cautious of pickpocketing and theft, especially in crowded areas like downtown and major attractions. Avoid unlicensed transportation services and be aware of common scams such as overcharging by taxi drivers or unofficial tour operators. It's advisable to keep personal belongings secure and use reputable transportation options to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Greenville, SC to Pittsburgh, PA
Greenville
Pittsburgh
The major bus station for departures in Greenville is Greenville, Woodruff Rd ("Raceway" gas station). Find all the information you need to know about services, amenities and connections at Greenville, Woodruff Rd ("Raceway" gas station) for your trip from Greenville to Pittsburgh.
Greenville, Woodruff Rd ("Raceway" gas station)
information
The major bus station for arrivals in Pittsburgh is Pittsburgh, Greyhound Bus Station. Find all the information you need to know about services, amenities and connections at Pittsburgh, Greyhound Bus Station for your trip to Pittsburgh from Greenville.
Pittsburgh, Greyhound Bus Station
information
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to Pittsburgh, PA
Here are some other resources that might have the information you need
Most popular buses to and from Pittsburgh, PA and Greenville, SC
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