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Journey information
Overview: Bus from Greenville, SC to Pittsburgh, PA
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 407 miles (656 km) |
Average bus duration 16h 5m |
Buses per day 4 |
First bus 01:35 |
Last bus 23:10 |
Key Takeaways
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus from Greenville, SC to Pittsburgh, PAYou can travel by bus between Greenville, SC to Pittsburgh, PA with FlixBus. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
20h 25m
Cheapest Price
$180 (€147)
FlixBus frequency
4 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
FAQs: Bus from Greenville, SC to Pittsburgh, PA
Find answers to the most common questions about traveling from Greenville, SC to Pittsburgh, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Pittsburgh, PA, this guide helps you travel smarter and with confidence.

Cheap bus tickets from Greenville, SC to Pittsburgh, PA can start from as little as $136 (€111) when you book in advance. The average bus ticket price for Greenville, SC to Pittsburgh, PA is $241 (€197); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Greenville, SC to Pittsburgh, PA is 20 h 10 min to travel the 407 mile (656 km) long route, with around there are 3 buses per day. Journey times can vary on weekends and holidays.
The first bus from Greenville, SC to Pittsburgh, PA leaves at 1: 35AM. Plan your trip with the Journey Planner from Omio.
The last bus from Greenville, SC to Pittsburgh, PA leaves at 11: 10PM.
There are 3 buses a day from Greenville, SC to Pittsburgh, PA which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
For the journey from Greenville, SC to Pittsburgh, PA you can take a bus with FlixBus. Be sure to check out all possible bus providers that offer services to Pittsburgh, PA from Greenville, SC on Omio to compare what amenities they may have.
The cheapest month to travel from Greenville, SC to Pittsburgh, PA by bus is November.
You have options as you can travel from Greenville, SC to Pittsburgh, PA 3 different ways: bus, flight or train.
Yes, the following accessibility options are available when taking the bus from Greenville, SC to Pittsburgh, PA:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Greenville, SC to Pittsburgh, PA for bus company FlixBus.
Some of the most interesting sights to explore in Pittsburgh, PA are:
- The Andy Warhol Museum, a comprehensive collection dedicated to the life and works of the iconic pop artist
- Phipps Conservatory and Botanical Gardens, a historic greenhouse with diverse plant exhibits and sustainable architecture
- Carnegie Museum of Natural History, featuring extensive dinosaur displays and global cultural artifacts
- Point State Park, a scenic urban park at the confluence of three rivers with historical significance
- Mount Washington, offering panoramic views of Pittsburgh's skyline from its renowned overlooks.
The best things to do in Pittsburgh, PA include:
- Heinz History Center, an affiliate of the Smithsonian Institution showcasing Western Pennsylvania's history and heritage
- Take a ride on the Duquesne Incline for a historic cable car experience and stunning city views
- Explore the Strip District, known for its vibrant markets, eateries, and unique shops
- Visit the National Aviary, home to a diverse collection of birds from around the world
- Enjoy a Pittsburgh Pirates game at PNC Park, renowned for its beautiful views of the city skyline.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from Greenville, SC to Pittsburgh, PA depends on the bus company:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Greenville, SC to Pittsburgh, PA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
Yes, there is food available to purchase on board the bus from Greenville, SC to Pittsburgh, PA.
Yes, the following luggage options are included when booking a bus ticket from Greenville, SC to Pittsburgh, PA:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Greenville, SC to Pittsburgh, PA:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Greenville, SC to Pittsburgh, PA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
You can reserve your seat on the bus from Greenville, SC to Pittsburgh, PA with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Greenville, SC to Pittsburgh, PA with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Greenville, SC to Pittsburgh, PA with the following bus company: FlixBus.
popular bus stations
Popular bus stations from Greenville, SC to Pittsburgh, PA
Greenville
Pittsburgh
The major bus station for departures in Greenville is Greenville, Woodruff Rd ("Raceway" gas station). Find all the information you need to know about services, amenities and connections at Greenville, Woodruff Rd ("Raceway" gas station) for your trip from Greenville to Pittsburgh.
Greenville, Woodruff Rd ("Raceway" gas station)
information
The major bus station for arrivals in Pittsburgh is Pittsburgh, Greyhound Bus Station. Find all the information you need to know about services, amenities and connections at Pittsburgh, Greyhound Bus Station for your trip to Pittsburgh from Greenville.
Pittsburgh, Greyhound Bus Station
information
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to Pittsburgh, PA
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