- Must visit
Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
The best way to find a cheap bus ticket from San Francisco, CA to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Francisco, CA to Orlando, FL will cost around $274 if you buy it on the day, but the cheapest tickets can be found for only $221.
It's difficult to get from San Francisco, CA to Orlando, FL without transferring at least 4 times.
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Buses from San Francisco, CA to Orlando, FL run on average 6 times per day, taking around 66h 50m. Cheap bus tickets for this journey start at $135 (€113) if you book in advance.
The earliest bus runs at 06:30, the last at 23:40. The fastest bus covers the 2437 miles (3922 km) distance in 63h 0m.
Distance 2437 miles (3922 km) |
Average bus duration 66h 50m |
Cheapest ticket price $135 (€113) |
Buses per day 6 |
Fastest bus 63h 0m |
First bus 6:30 AM |
Last bus 11:40 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 84 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from San Francisco, CA to Orlando, FL.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:05AM | Arrival Time 02:35AM | Duration 71h30 | Departure days Wed, Sun | Cheapest price $173 |
Operator Greyhound | Departure Time 05:40AM | Arrival Time 04:35AM | Duration 70h55 | Departure days Wed | Cheapest price $182 |
Operator Greyhound | Departure Time 06:25AM | Arrival Time 05:50AM | Duration 71h25 | Departure days Fri | Cheapest price $400 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 07:50AM | Duration 70h20 | Departure days Wed, Sun | Cheapest price $183 |
Operator Greyhound | Departure Time 06:40AM | Arrival Time 06:50AM | Duration 72h10 | Departure days Tue, Wed | Cheapest price $391 |
Operator Greyhound | Departure Time 07:10AM | Arrival Time 07:50AM | Duration 69h40 | Departure days Wed | Cheapest price $173 |
Operator Greyhound | Departure Time 07:40AM | Arrival Time 04:20PM | Duration 77h40 | Departure days Sun | Cheapest price $221 |
Operator Greyhound | Departure Time 08:40AM | Arrival Time 11:59PM | Duration 84h19 | Departure days Wed | Cheapest price $181 |
Operator Greyhound | Departure Time 01:10PM | Arrival Time 04:20PM | Duration 72h10 | Departure days Wed, Sun | Cheapest price $173 |
Operator Greyhound | Departure Time 01:30PM | Arrival Time 11:50AM | Duration 70h20 | Departure days Fri | Cheapest price $229 |
Operator Greyhound | Departure Time 02:30PM | Arrival Time 06:55PM | Duration 76h25 | Departure days Tue, Sat | Cheapest price $293 |
Operator Greyhound | Departure Time 03:20PM | Arrival Time 11:45AM | Duration 68h25 | Departure days Tue | Cheapest price $209 |
Operator Greyhound | Departure Time 06:05PM | Arrival Time 06:25AM | Duration 81h20 | Departure days Wed, Sun | Cheapest price $187 |
Operator Greyhound | Departure Time 07:05PM | Arrival Time 08:20PM | Duration 73h15 | Departure days Fri | Cheapest price $117 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 03:59AM | Duration 79h29 | Departure days Mon, Tue, Fri, Sat | Cheapest price $176 |
Operator Greyhound | Departure Time 08:40PM | Arrival Time 09:20PM | Duration 72h40 | Departure days Sat | Cheapest price $189 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 09:20PM | Duration 71h50 | Departure days Mon, Thu, Fri | Cheapest price $178 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 02:35AM | Duration 73h05 | Departure days Wed, Sun | Cheapest price $201 |
The table below shows live departures for San Francisco, CA to Orlando, FL buses for today, Saturday, October 31. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:30 PM San Francisco, CA | 79h29 | 3:59 AM Orlando, FL | 0 transfersDirect | |
![]() | 8:40 PM San Francisco, CA | 72h40 | 9:20 PM Orlando, FL | 0 transfersDirect | |
| Sunday, November 1 | |||||
FlixBus+ · · | 1:05 AM San Francisco, Townsend Street / 5th Street, CA | 71h30 | 2:35 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 5 transfers | |
· · · | 6:30 AM San Francisco, Transit Center Bay 29 | 70h20 | 7:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 5 transfers | |
FlixBus+ · · | 7:40 AM San Francisco, Townsend Street / 5th Street, CA | 77h40 | 4:20 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 4 transfers | |
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Orlando, FL.
Find answers to the most common questions about traveling from San Francisco, CA to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

Most San Francisco, CA to Orlando, FL buses use the San Francisco, Transit Center Bay 29 to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair, with some services arriving at Orlando, The Florida Mall. Use this guide to compare San Francisco, CA and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
San Francisco, Transit Center Bay 29 is 2 km from San Francisco city centre. Public transport options include:
San Francisco, Transit Center Bay 29 has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Francisco, Transit Center Bay 29. ATMs are available at San Francisco, Transit Center Bay 29.
Ticket office support is available at San Francisco, Transit Center Bay 29.
Available at San Francisco, Transit Center Bay 29: Parking, Taxis, WC.
Accessibility facilities are available at San Francisco, Transit Center Bay 29: Wheelchair accessible areas present.
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Check bus stations information for San Francisco, CA and Orlando, FL, including where buses depart and arrive on this route.
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