- Must visit
The Strong National Museum of Play
Major interactive museum focused on play, toys, games, and childhood culture. One of Rochester's signature attractions and especially popular with families.
Cheapest price
$160
Average price
$180
Fastest journey
1 d
Average duration
1 d 2 h 1 m
Buses per day
4
Distance
1011 km
The best way to find a cheap bus ticket from Greenville, SC to Rochester, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Rochester, NY will cost around $180 if you buy it on the day, but the cheapest tickets can be found for only $160.
It's difficult to get from Greenville, SC to Rochester, NY without transferring at least 2 times.
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FlixBus · FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Greenville, SC to Rochester, NY among Omio's users. If you are prioritising price take the bus with prices starting from $162. For those with little time consider booking a flight which can get you there in 4h 51m. The ticket price range depends on the travel mode: a bus costs an average of $162, and a flight costs an average of $159.
Distance: 628 miles (1011 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$163 Average price Cheapest | $257 Average price | $160 Average price (fuel + tolls) |
25h 43m Average total duration 25h 13m Onboard + 30m Additional time* | 7h 51m Average total duration Fastest 4h 51m Onboard + 3h 0m Additional time* | 12h 26m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Rochester, NY:
A bus is $94 (€77) less than a flight for this route with tickets for a flight from Greenville, SC to Rochester, NY costing on average $257 (€211).
Other travel options to Rochester, NY take longer:
Bus takes on average 25h 13m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:10AM | Arrival Time 07:10AM | Duration 24h00 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $139 |
Operator Greyhound | Departure Time 11:00AM | Arrival Time 03:25PM | Duration 28h25 | Departure days Tue | Cheapest price $135 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 01:30PM | Duration 25h15 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $137 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 05:15PM | Duration 25h00 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $136 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 03:25AM | Duration 29h50 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $137 |
The table below shows live departures for Greenville, SC to Rochester, NY buses for today, Thursday, July 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· + FlixBus | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 24h00 | 7:10 AM Rochester, Pleasant St (Greyhound Stop), NY | 2 transfers | |
FlixBus+ · | 12:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 25h15 | 1:30 PM Rochester, Pleasant St (Greyhound Stop), NY | 2 transfers | |
FlixBus+ + FlixBus | 4:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 25h00 | 5:15 PM Rochester, Pleasant St (Greyhound Stop), NY | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 29h50 | 3:25 AM Rochester, Pleasant St (Greyhound Stop), NY | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, SC to Rochester, NY run on average 4 times per day, taking around 25h 13m. Cheap bus tickets for this journey start at $162 (€133) but you can travel from only $159 (€131) by flight.
The earliest bus runs at 00:35, the last at 23:50. The fastest bus covers the 628 miles (1011 km) distance in 25h 10m.
Distance 628 miles (1011 km) |
Average bus duration 25h 13m |
Cheapest ticket price $162 (€133) |
Buses per day 4 |
Fastest bus 25h 10m |
First bus 12:35 AM |
Last bus 11:50 PM |
Cheapest Month Feb |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 7 days |
Discover the best of Rochester — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rochester trip today.
Major interactive museum focused on play, toys, games, and childhood culture. One of Rochester's signature attractions and especially popular with families.
World-renowned photography and cinema museum in the historic Eastman estate. Known for exhibitions, gardens, and film heritage.
Well-regarded art museum with collections spanning ancient to contemporary works, plus strong regional and temporary exhibitions.
Revitalized riverfront area around the waterfall, popular for views, industrial heritage, and photography.
Historic park famous for landscape design, lilacs, and seasonal color. A local favorite for walks and spring visits.
Walkable neighborhood corridor lined with historic homes, boutiques, and leafy streets. One of Rochester's most pleasant areas for a stroll.
Rochester’s signature late-night dish with home fries or macaroni salad, topped with meats, baked beans, onions, mustard, and hot meat sauce.
A distinctive pale pork, beef, and veal hot dog created in Rochester, prized for its mild flavor and snap.
A classic Rochester hot dog with a smoky flavor, closely tied to local cookouts, diners, and baseball games.
A popular neighborhood restaurant known for creative comfort food, strong vegetarian options, and a relaxed, artsy setting.
A well-known contemporary restaurant with a stylish industrial dining room, noted for seasonal American dishes and craft cocktails.
An established Italian restaurant overlooking the Genesee River, appreciated for pasta, seafood, and a more polished atmosphere.
Generally affordable by U.S. city standards. Hotels and dining are moderate, with good budget options and lower costs than major coastal cities.
Tip 18-20% at sit-down restaurants before tax. Tip USD 1-2 per drink at bars, round up or add 10-15% for taxis, and tip hotel staff USD 1-5 depending on service.
Find answers to the most common questions about traveling from Greenville, SC to Rochester, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rochester, NY, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Rochester, NY buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Rochester, Pleasant St (Greyhound Stop) station pair. Use this guide to compare Greenville, SC and Rochester, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need