- Must visit
Everson Museum of Art
Major regional museum covering art, science, and history. Best known for broad collections, family appeal, and exhibits on Central New York.
Cheapest price on Sep 19
$101
Average ticket price on Sep 19
$111
Fastest journey on Sep 19
23 h
Average journey duration on Sep 19
23 h 54 m
Buses on Sep 19
5
Distance
1059 km
The best way to find a cheap bus ticket from Greenville, SC to Syracuse, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Syracuse, NY will cost around $111 if you buy it on the day, but the cheapest tickets can be found for only $101.
It's difficult to get from Greenville, SC to Syracuse, NY without transferring at least once.
·
·
FlixBus+
+
FlixBus
FlixBus · FlixBus · FlixBus
·
FlixBus+
+
FlixBus
·
·
·
FlixBus · FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Greenville, SC to Syracuse, NY among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $151 For those with little time, consider booking a flight, which has an average total journey time of 5h 48m. Average ticket prices depend on the travel mode: a bus costs an average of $151, while a flight costs an average of $905.
Distance: 658 miles (1059 km)
Most popular Bus | Flight | Driving |
|---|---|---|
$151 Average price Cheapest | $905 Average price | $158 Average price (fuel + tolls) |
21h 44m Average total duration 21h 14m Onboard + 30m Additional time* | 5h 48m Average total duration Fastest 3h 48m Onboard + 2h 0m Additional time* | 12h 22m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Syracuse, NY:
A bus is $753 less than a flight for this route with tickets for a flight from Greenville, SC to Syracuse, NY costing on average $905.
Other travel options to Syracuse, NY take longer:
Bus takes on average 21h 14m.
Tickets start at around $151 compared to roughly $158 in fuel and tolls — a saving of about $7. The journey takes 21h 14m versus 12h 22m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 03:55AM | Duration 24h30 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $111 |
Operator Greyhound | Departure Time 07:10AM | Arrival Time 06:10AM | Duration 23h00 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $84 |
Operator Greyhound | Departure Time 11:00AM | Arrival Time 11:20AM | Duration 24h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $93 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 09:05AM | Duration 21h55 | Departure days Wed | Cheapest price $179 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 01:35PM | Duration 24h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $101 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 03:15PM | Duration 23h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $96 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 08:10PM | Duration 22h35 | Departure days Mon, Tue, Fri | Cheapest price $89 |
The table below shows live departures for Greenville, SC to Syracuse, NY buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ · | 9:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 22h35 | 8:10 PM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 2 transfers | |
| Saturday, September 19 | |||||
· | 3:25 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 24h30 | 3:55 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 1 transfer | |
· | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 23h00 | 6:10 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 1 transfer | |
· | 11:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 24h20 | 11:20 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 1 transfer | |
FlixBus · FlixBus · FlixBus | 12:55 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 24h40 | 1:35 PM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 2 transfers | |
FlixBus · FlixBus+![]() | 4:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 23h00 | 3:15 PM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, SC to Syracuse, NY run on average 5 times per day, taking around 21h 14m. Cheap bus tickets for this journey start at $106 if you book in advance.
The earliest bus runs at 07:10, the last at 22:00. The fastest bus covers the 658 miles (1059 km) distance in 19h 20m.
Distance 658 miles (1059 km) |
Average bus duration 21h 14m |
Cheapest ticket price $106 |
Buses per day 5 |
Fastest bus 19h 20m |
First bus 7:10 AM |
Last bus 10:00 PM |
Cheapest Month Aug |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Discover the best of Syracuse, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse, NY trip today.
Major regional museum covering art, science, and history. Best known for broad collections, family appeal, and exhibits on Central New York.
Historic house museum preserving nineteenth-century Syracuse domestic life. Worth visiting for period rooms and insight into early city society.
Interactive museum focused on science and technology, famous for hands-on exhibits and domed IMAX theater. Great for families and curious visitors.
Historic downtown square and year-round gathering place, known for festivals, fountains, and winter skating. A central stop for city atmosphere.
Scenic waterfront park with long trails, lake views, and birdlife. Popular for walking, cycling, and relaxing near Syracuse's restored shoreline.
Compact downtown district filled with galleries, murals, and restored warehouse buildings. Best explored on foot for arts culture and architecture.
Salt potatoes are small potatoes boiled in heavily salted water, creating a crusty skin and creamy center. They are a Central New York summer staple, often served with butter.
Chicken riggies is a spicy Utica pasta dish popular across Central New York, made with chicken, rigatoni, peppers, and a creamy tomato sauce.
Utica greens are escarole sautéed with hot peppers, garlic, breadcrumbs, and often prosciutto. This Italian American side is beloved throughout the Syracuse area.
Long running market cafe and bakery known for tomato pie, sandwiches, pastries, and a classic Syracuse neighborhood feel.
Established Italian restaurant known for homemade pasta, regional Italian American dishes, and a polished but welcoming atmosphere.
Upscale downtown dining with seasonal American cuisine, thoughtful plating, and a refined setting popular for special occasions.
Moderate for a U.S. city. Hotels are often cheaper than NYC, dining is mid-priced, and most visitors need a car or rideshares as transit is limited.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts for small tips.
Find answers to the most common questions about traveling from Greenville, SC to Syracuse, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Syracuse, NY buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Syracuse, Walsh Cir (Syracuse Bus Station) station pair. Use this guide to compare Greenville, SC and Syracuse, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Limited dining options available in adjacent areas.
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Syracuse, Walsh Cir (Syracuse Bus Station) is 3 km from Syracuse city centre. Public transport options include:
Syracuse, Walsh Cir (Syracuse Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available throughout the station. ATMs are aTMs are located near the entrance.
Ticket office support is available at Syracuse, Walsh Cir (Syracuse Bus Station).
Available at Syracuse, Walsh Cir (Syracuse Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Syracuse, Walsh Cir (Syracuse Bus Station): The station is wheelchair accessible.
Here are some other resources that might have the information you need