- Must visit
Everson Museum of Art
Major regional museum covering art, science, and history. Best known for broad collections, family appeal, and exhibits on Central New York.
The best way to find a cheap bus ticket from Greenville, SC to Syracuse, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Syracuse, NY will cost around €147 if you buy it on the day, but the cheapest tickets can be found for only €147.
On Wed, Nov 04, we found 1 buses from Greenville, SC to Syracuse, NY, including 1 direct services.
On Wed, Nov 04 the direct buses cover the 1059 km distance in an average of 21 h 55 m but if you time it right, some buses will get you there in just 21 h 55 m .
On Wed, Nov 04 the slowest buses will take 21 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Greenville, SC to Syracuse, NY run on average 5 times per day, taking around 21h 25m. Cheap bus tickets for this journey start at €69 if you book in advance.
The earliest bus runs at 07:10, the last at 22:00. The fastest bus covers the 658 miles (1059 km) distance in 19h 20m.
Distance 658 miles (1059 km) |
Average bus duration 21h 25m |
Cheapest ticket price €69 |
Buses per day 5 |
Fastest bus 19h 20m |
First bus 7:10 AM |
Last bus 10:00 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Greenville, SC to Syracuse, NY.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 03:55AM | Duration 24h30 | Departure days Tue, Thu, Fri | Cheapest price €99 |
Operator Greyhound | Departure Time 07:10AM | Arrival Time 06:10AM | Duration 23h00 | Departure days Tue, Thu, Fri | Cheapest price €86 |
Operator Greyhound | Departure Time 11:00AM | Arrival Time 11:20AM | Duration 24h20 | Departure days Tue, Thu, Fri | Cheapest price €86 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 09:05AM | Duration 21h55 | Departure days Wed | Cheapest price €147 |
Operator Greyhound | Departure Time 12:25PM | Arrival Time 10:05AM | Duration 21h40 | Departure days Sat | Cheapest price €166 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 01:35PM | Duration 24h40 | Departure days Thu, Fri | Cheapest price €94 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 03:15PM | Duration 23h00 | Departure days Thu, Fri | Cheapest price €85 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 08:10PM | Duration 22h35 | Departure days Tue, Fri | Cheapest price €86 |
The table below shows live departures for Greenville, SC to Syracuse, NY buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 3:25 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 24h30 | 3:55 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 1 transfer | |
· | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 23h00 | 6:10 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 1 transfer | |
· | 11:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 24h20 | 11:20 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 1 transfer | |
This is the last bus of the day. | |||||
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Discover the best of Syracuse, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse, NY trip today.
Major regional museum covering art, science, and history. Best known for broad collections, family appeal, and exhibits on Central New York.
Historic house museum preserving nineteenth-century Syracuse domestic life. Worth visiting for period rooms and insight into early city society.
Interactive museum focused on science and technology, famous for hands-on exhibits and domed IMAX theater. Great for families and curious visitors.
Historic downtown square and year-round gathering place, known for festivals, fountains, and winter skating. A central stop for city atmosphere.
Scenic waterfront park with long trails, lake views, and birdlife. Popular for walking, cycling, and relaxing near Syracuse's restored shoreline.
Compact downtown district filled with galleries, murals, and restored warehouse buildings. Best explored on foot for arts culture and architecture.
Salt potatoes are small potatoes boiled in heavily salted water, creating a crusty skin and creamy center. They are a Central New York summer staple, often served with butter.
Chicken riggies is a spicy Utica pasta dish popular across Central New York, made with chicken, rigatoni, peppers, and a creamy tomato sauce.
Utica greens are escarole sautéed with hot peppers, garlic, breadcrumbs, and often prosciutto. This Italian American side is beloved throughout the Syracuse area.
Long running market cafe and bakery known for tomato pie, sandwiches, pastries, and a classic Syracuse neighborhood feel.
Established Italian restaurant known for homemade pasta, regional Italian American dishes, and a polished but welcoming atmosphere.
Upscale downtown dining with seasonal American cuisine, thoughtful plating, and a refined setting popular for special occasions.
Moderate for a U.S. city. Hotels are often cheaper than NYC, dining is mid-priced, and most visitors need a car or rideshares as transit is limited.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts for small tips.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Syracuse, NY.
Find answers to the most common questions about traveling from Greenville, SC to Syracuse, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.

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