- Must visit
Everson Museum Of Art
A major American art museum known for its ceramics collection and notable modern architecture by I. M. Pei. It is one of Syracuse’s top cultural attractions.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Greenville, SC to Syracuse, NY
Showing times and prices for Jun 21
Cheapest price
$166
Average price
$183
Fastest journey
23 h
Average duration
23 h 24 m
Buses per day
4
Distance
1059 km
Cheap tickets
The best way to find a cheap bus ticket from Greenville, SC to Syracuse, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Syracuse, NY will cost around $183 if you buy it on the day, but the cheapest tickets can be found for only $166.
Fast buses
It's difficult to get from Greenville, SC to Syracuse, NY without transferring at least once.
· 7:10 AM23h00Greenville, Woodruff Rd ("Raceway" gas station), SC6:10 AMSyracuse, Walsh Cir (Syracuse Bus Station), NY$1661One-way1 transfer
FlixBus · FlixBus+4:15 PM23h00Greenville, Woodruff Rd ("Raceway" gas station), SC3:15 PMSyracuse, Walsh Cir (Syracuse Bus Station), NY$1791One-way2 transfers- FlixBus+ · 12:15 PM23h05Greenville, Woodruff Rd ("Raceway" gas station), SC11:20 AMSyracuse, Walsh Cir (Syracuse Bus Station), NY$1891One-way2 transfers
- · 3:25 AM24h30Greenville, Woodruff Rd ("Raceway" gas station), SC3:55 AMSyracuse, Walsh Cir (Syracuse Bus Station), NY$1991One-way1 transfer
- · 7:10 AM23h00Greenville, Woodruff Rd ("Raceway" gas station), SC6:10 AMSyracuse, Walsh Cir (Syracuse Bus Station), NY$1661One-way1 transfer
- FlixBus · FlixBus+4:15 PM23h00Greenville, Woodruff Rd ("Raceway" gas station), SC3:15 PMSyracuse, Walsh Cir (Syracuse Bus Station), NY$1791One-way2 transfers
- FlixBus+ · 12:15 PM23h05Greenville, Woodruff Rd ("Raceway" gas station), SC11:20 AMSyracuse, Walsh Cir (Syracuse Bus Station), NY$1891One-way2 transfers
- · 3:25 AM24h30Greenville, Woodruff Rd ("Raceway" gas station), SC3:55 AMSyracuse, Walsh Cir (Syracuse Bus Station), NY$1991One-way1 transfer
Travel Information
Compare bus and flight for Greenville, SC to Syracuse, NY
Omio recommends booking the flight as it is the most popular option from Greenville, SC to Syracuse, NY among Omio's users. If you are prioritising price take the bus with prices starting from $144. For those with little time consider booking a flight which can get you there in 5h 37m. The ticket price range depends on the travel mode: a bus costs an average of $144, and a flight costs an average of $363.
Distance: 658 miles (1059 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$170 Average price Cheapest | $423 Average price | $156 Average price (fuel + tolls) |
22h 55m Average total duration 22h 25m Onboard + 30m Additional time* | 8h 37m Average total duration Fastest 5h 37m Onboard + 3h 0m Additional time* | 12h 22m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Greenville, SC to Syracuse, NY is a bus with an average price of $170 (€139).
This is compared to other travel options from Greenville, SC to Syracuse, NY:
A bus is $254 (€207) less than a flight for this route with tickets for a flight from Greenville, SC to Syracuse, NY costing on average $423 (€346).
The fastest way to travel from Greenville, SC to Syracuse, NY is by flight with an average journey time of 5h 37m.
Other travel options to Syracuse, NY take longer:
Bus takes on average 22h 25m.
It's helpful to compare your options as there are 2 ways to travel between Greenville, SC and Syracuse, NY including taking a bus and flight.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Greenville, SC to Syracuse, NY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 03:55AM | Duration 24h30 | Departure days Fri, Sat, Sun | Cheapest price $152 |
Operator Greyhound | Departure Time 07:10AM | Arrival Time 06:10AM | Duration 23h00 | Departure days Fri, Sat, Sun | Cheapest price $145 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 09:05AM | Duration 21h55 | Departure days Wed | Cheapest price $180 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 11:20AM | Duration 23h05 | Departure days Fri, Sat, Sun | Cheapest price $148 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 03:20PM | Duration 23h05 | Departure days Thu, Fri, Sat, Sun | Cheapest price $154 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 07:30PM | Duration 21h55 | Departure days Fri | Cheapest price $183 |
Live departures
Greenville, SC to Syracuse, NY bus times
The table below shows live departures for Greenville, SC to Syracuse, NY buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 23h00 | 6:10 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 1 transfer | |
| FlixBus+ · | 12:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 23h05 | 11:20 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 2 transfers | |
| FlixBus++FlixBus | 4:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 23h00 | 3:15 PM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 2 transfers | |
| Sunday, June 21 | |||||
| · | 3:25 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 24h30 | 3:55 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to Syracuse, NY by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sun
Jun 21
Jun 21
Mon
Jun 22
Jun 22
Tue
Jun 23
Jun 23
Wed
Jun 24
Jun 24
Thu
Jun 25
Jun 25
Fri
Jun 26
Jun 26
Sat
Jun 27
Jun 27
Journey information
Overview: Bus from Greenville, SC to Syracuse, NY
USAUSA
Buses from Greenville, SC to Syracuse, NY run on average 4 times per day, taking around 22h 25m. Cheap bus tickets for this journey start at $144 (€117) if you book in advance.
The earliest bus runs at 07:10, the last at 22:00. The fastest bus covers the 658 miles (1059 km) distance in 21h 40m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 658 miles (1059 km) |
Average bus duration 22h 25m |
Cheapest ticket price $144 (€117) |
Buses per day 4 |
Fastest bus 21h 40m |
First bus 7:10 AM |
Last bus 10:00 PM |
Cheapest Month Feb |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Complete guide to Syracuse
Things to do in Syracuse
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
- Recommended
Erie Canal Museum
A local history museum in the last remaining weighlock building in the United States, focusing on the Erie Canal’s impact on Syracuse and New York State.
- Recommended
Museum Of Science & Technology
A hands-on science museum in downtown Syracuse with interactive exhibits and a planetarium, popular with families and visitors interested in STEM.
- Must visit
Armory Square
Syracuse’s best-known historic district, filled with restored warehouses, lively streets, and a strong mix of shopping, architecture, and nightlife.
- Must visit
Onondaga Lake Park
A popular waterfront recreation area with trails, lake views, and sunset spots that are frequently featured in local social media posts.
- Recommended
Clinton Square
A central downtown square known for historic buildings, events, and seasonal programming, including its popular winter ice rink.
- Vegetarian
- Gluten-free
Salt Potatoes
Small potatoes boiled in very salty water until the skins wrinkle, then served with melted butter. They are a signature Central New York dish with roots in the region's salt industry.
Chicken Riggies
A spicy pasta dish with chicken, rigatoni, peppers, and a creamy tomato sauce. Though more closely tied to nearby Utica, it is widely loved across Central New York and commonly found in Syracuse.
- Vegetarian
- Vegan
Tomato Pie
A bakery-style rectangular pizza served at room temperature with thick crust, tomato sauce, and little or no cheese. It is a classic Upstate New York snack and party food.
Pastabilities
A long-running Syracuse favorite known for handmade pasta, spicy hot tomato oil, and a lively downtown atmosphere.
Francesca's Cucina
An established Italian restaurant on the north side, appreciated for classic pasta dishes, warm service, and a cozy neighborhood feel.
Dinosaur Bar-B-Que
A famous casual barbecue restaurant and roadhouse-style venue known for smoked meats, classic sides, and a bustling, iconic setting.
United States Dollar
Costs are moderate by U.S. standards. Casual dining is affordable, while hotels and fine dining cost more during peak dates.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 20-35 per person at a casual restaurant.
- Fine dining
- USD 50-90 per person before drinks.
- Coffee
- USD 3-6 for a coffee drink.
Tipping culture
Tip 18-20% at sit-down restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
FAQs: Bus from Greenville, SC to Syracuse, NY
Find answers to the most common questions about traveling from Greenville, SC to Syracuse, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Greenville, SC to Syracuse, NY can start from as little as $144 (€117) when you book in advance. The average bus ticket price for Greenville, SC to Syracuse, NY is $170 (€139) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Greenville, SC to Syracuse, NY is 21h 40m to travel the 658 miles (1059 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Greenville, SC to Syracuse, NY leaves at 7:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Greenville, SC to Syracuse, NY leaves at 10:00 PM.
A trip to Syracuse, NY from Greenville, SC is worth doing but not as a day trip with a journey time of 21h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Greenville, SC to Syracuse, NY is February.
It's helpful to compare your options as there are 2 ways to travel between Greenville, SC and Syracuse, NY including taking a bus and flight.
No, the bus from Greenville, SC to Syracuse, NY has no accessibility options.
No, there are no bathrooms on board the bus from Greenville, SC to Syracuse, NY.
No, bikes are not allowed on board the bus from Greenville, SC to Syracuse, NY.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Greenville, SC to Syracuse, NY.
No, luggage for the bus from Greenville, SC to Syracuse, NY needs to be booked in addition.
No, there are no additional luggage options for the bus from Greenville, SC to Syracuse, NY.
Unfortunately, pets are not allowed on the bus from Greenville, SC to Syracuse, NY.
No, there are no USB plugs on board the bus from Greenville, SC to Syracuse, NY.
No, there is no WiFi on board the bus from Greenville, SC to Syracuse, NY.
Since neither Greenville, SC nor Syracuse, NY are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Syracuse, NY, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Common scams include overcharging by taxis or ride services and fraudulent ticket sales for local events. It's advisable to use authorized transportation providers and remain vigilant when handling cash or personal belongings.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Greenville, SC to Syracuse, NY
Most Greenville, SC to Syracuse, NY buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Syracuse, Walsh Cir (Syracuse Bus Station) station pair. Use this guide to compare Greenville, SC and Syracuse, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Greenville
Arrival bus stations in Syracuse
Greenville, Woodruff Rd ("Raceway" gas station)
Syracuse, Walsh Cir (Syracuse Bus Station)
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to Syracuse, NY
Here are some other resources that might have the information you need
Most popular buses to and from Syracuse, NY and Greenville, SC
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
