- Must visit
Art Institute of Chicago
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Cheapest price
$117
Average price
$126
Fastest journey
22 h 55 m
Average duration
1 d 2 h 4 m
Buses per day
5
Distance
934 km
The best way to find a cheap bus ticket from Greensboro, NC to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greensboro, NC to Chicago, IL will cost around $126 if you buy it on the day, but the cheapest tickets can be found for only $117.
It's difficult to get from Greensboro, NC to Chicago, IL without transferring at least once.
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Omio recommends booking the train as it is the most popular option from Greensboro, NC to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $108. For those with little time consider booking a flight which can get you there in 5h 23m. The ticket price range depends on the travel mode: a bus costs an average of $108, and a train costs an average of $162.
Distance: 580 miles (934 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$217 Average price Cheapest | $337 Average price | $335 Average price |
21h 50m Average total duration 21h 20m Onboard + 30m Additional time* | 24h 37m Average total duration 24h 7m Onboard + 30m Additional time* | 8h 23m Average total duration Fastest 5h 23m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greensboro, NC to Chicago, IL:
A bus is $118 less than a flight for this route with tickets for a flight from Greensboro, NC to Chicago, IL costing on average $335.
A bus is $121 less than a train for this route with tickets for a train from Greensboro, NC to Chicago, IL costing on average $337.
Other travel options to Chicago, IL take longer:
Bus takes on average 21h 20m.
Train takes on average 24h 7m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:15AM | Arrival Time 12:10AM | Duration 22h55 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $110 |
Operator Greyhound | Departure Time 09:30AM | Arrival Time 08:25AM | Duration 23h55 | Departure days Everyday | Cheapest price $116 |
Operator Greyhound | Departure Time 03:40PM | Arrival Time 03:15PM | Duration 24h35 | Departure days Mon, Tue, Fri, Sat | Cheapest price $108 |
Operator Greyhound | Departure Time 03:45PM | Arrival Time 03:15PM | Duration 24h30 | Departure days Sun | Cheapest price $124 |
Operator Greyhound | Departure Time 05:10PM | Arrival Time 08:10PM | Duration 28h00 | Departure days Sun | Cheapest price $124 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 12:10AM | Duration 26h05 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $110 |
Operator Greyhound | Departure Time 11:05PM | Arrival Time 08:00AM | Duration 33h55 | Departure days Everyday | Cheapest price $116 |
The table below shows live departures for Greensboro, NC to Chicago, IL buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 9:30 AM Greensboro, E Washington St (Greyhound Bus Station), NC | 23h30 | 8:00 AM Chicago, Union Station (Amtrak), IL | 1 transfer | |
FlixBus+![]() | 9:30 AM Greensboro, E Washington St (Greyhound Bus Station), NC | 23h55 | 8:25 AM Chicago, Greyhound Bus Station | 1 transfer | |
FlixBus+![]() | 3:40 PM Greensboro, E Washington St (Greyhound Bus Station), NC | 24h35 | 3:15 PM Chicago, Greyhound Bus Station | 1 transfer | |
FlixBus · FlixBus | 11:05 PM Greensboro, E Washington St (Greyhound Bus Station), NC | 26h05 | 12:10 AM Chicago, Greyhound Bus Station | 1 transfer | |
FlixBus · FlixBus+![]() | 11:05 PM Greensboro, E Washington St (Greyhound Bus Station), NC | 33h55 | 8:00 AM Chicago, Union Station (Amtrak), IL | 2 transfers | |
FlixBus+![]() | 2:15 AM Greensboro, E Washington St (Greyhound Bus Station), NC | 22h55 | 12:10 AM Chicago, Greyhound Bus Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greensboro, NC to Chicago, IL run on average 6 times per day, taking around 21h 20m. Cheap bus tickets for this journey start at $108 if you book in advance.
The earliest bus runs at 00:20, the last at 23:50. The fastest bus covers the 580 miles (934 km) distance in 22h 55m.
Distance 580 miles (934 km) |
Average bus duration 21h 20m |
Cheapest ticket price $108 |
Buses per day 6 |
Fastest bus 22h 55m |
First bus 12:20 AM |
Last bus 11:50 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 14 days |
Discover the best of Chicago, IL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago, IL trip today.
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Major natural history museum with Sue the T. rex, ancient cultures, and strong family appeal.
Hands-on science museum in a grand former fair building, popular for exhibits and a U-505 submarine.
Lively lakefront park with Cloud Gate, Crown Fountain, gardens, and major public art in central Chicago.
Famous shopping boulevard lined with architecture, hotels, riverfront views, and major city energy.
Scenic pedestrian-friendly riverwalk with boat docks, public art, bridges, and standout skyline perspectives.
Deep-dish pizza is Chicago’s iconic pie with a tall buttery crust, layers of cheese and toppings, and chunky tomato sauce baked on top.
The Chicago-style hot dog is an all-beef frank on a poppy seed bun with mustard, relish, onion, tomato, pickle, peppers, and celery salt.
Italian beef is thin-sliced roast beef piled onto a roll, often dipped in savory juices and topped with sweet peppers or spicy giardiniera.
Classic spot for juicy Italian beef sandwiches, especially dipped and topped with spicy giardiniera, with a casual local feel.
Legendary stand for Chicago-style hot dogs and char-grilled sausages, served fast in a no-frills local landmark.
World-famous fine dining destination offering a highly creative tasting menu and refined service in an elegant setting.
Moderate for a major US city: hotels can be pricey, but transit is affordable and dining ranges from cheap eats to upscale options.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and optional small change at cafes.
Find answers to the most common questions about traveling from Greensboro, NC to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

Most Greensboro, NC to Chicago, IL buses use the Greensboro, E Washington St (Greyhound Bus Station) to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare Greensboro, NC and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need