- Must visit
Greenville County Museum of Art
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
Flights from Greensboro, NC to Greenville, SC depart on average 18 times per day, taking around 5h 13m. Cheap flight tickets for this journey start at $188 (€154) but you can travel from only $34 (€27) by bus.
The earliest flight runs at 05:00, the last at 20:53. The fastest flight covers the 169 miles (272 km) distance in 2h 46m. October is the cheapest month to fly.
Distance 169 miles (272 km) |
Average flight duration 5h 13m |
Cheapest ticket price $188 (€154) |
Flights per day 18 |
Fastest flight 2h 46m |
First flight 5:00 AM |
Last flight 8:53 PM |
Cheapest Month Oct |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Sun |
Least Busy Day Sat |
Cheapest price
$232
Average price
$330
Fastest journey
4 h 52 m
Average duration
4 h 57 m
Flights per day
2
Distance
272 km
The best way to find a cheap flight ticket from Greensboro, NC to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greensboro, NC to Greenville, SC will cost around $330 if you buy it on the day, but the cheapest tickets can be found for only $232.
Of the 2 flights that leave Greensboro, NC for Greenville, SC onSun, Jun 21, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct flights cover the 272 km distance in an average of 4 h 57 m but if you time it right, some flights will get you there in just 4 h 52 m .
On Sun, Jun 21 the longest flights will take 5 h 1 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from Greensboro, NC to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $34. For those with little time consider booking a bus which can get you there in 4h 18m. The ticket price range depends on the travel mode: a bus costs an average of $34, and a flight costs an average of $188.
Distance: 169 miles (272 km)
| Flight | Most popular Train | Bus | Driving |
|---|---|---|---|
$369 Average price | $74 Average price | $43 Average price Cheapest | $39 Average price (fuel + tolls) |
8h 13m Average total duration 5h 13m Onboard + 3h 0m Additional time* | 5h 23m Average total duration 4h 53m Onboard + 30m Additional time* | 4h 48m Average total duration Fastest 4h 18m Onboard + 30m Additional time* | 2h 48m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greensboro, NC to Greenville, SC:
A bus is $31 (€26) less than a train for this route with tickets for a train from Greensboro, NC to Greenville, SC costing on average $74 (€61).
A bus is $326 (€266) less than a flight for this route with tickets for a flight from Greensboro, NC to Greenville, SC costing on average $369 (€302).
Other travel options to Greenville, SC take longer:
Train takes on average 4h 53m.
Flight takes on average 5h 13m.
The table below shows live departures for Greensboro, NC to Greenville, SC flights for tomorrow, Sunday, June 21. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:18 AM Greensboro, NC | 5h01 | 2:19 PM Greenville, SC | 0 transfersDirect | |
![]() | 11:30 AM Greensboro, NC | 4h52 | 4:22 PM Greenville, SC | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
Regional history museum with permanent and rotating exhibits on the people and stories of Upstate South Carolina. A strong choice for understanding Greenville’s local context.
Specialized museum displaying rare historic instruments from around the world. A distinctive local favorite for music, design, and cultural history.
Greenville’s central downtown street lined with shops, public art, plazas, and event spaces. It is the main place to walk and experience the city atmosphere.
Downtown park built around waterfalls, gardens, and river overlooks. It is Greenville’s signature public space and a top stop for first-time visitors.
Popular multi-use greenway for walking and cycling, linking Greenville with nearby communities. Widely loved by locals and visitors for active sightseeing.
Slow-smoked pork, often chopped or pulled, served with the state's signature mustard-based sauce. It is a defining Upstate and South Carolina tradition.
Slices of unripe tomato coated and fried until crisp, often served with remoulade or pimento cheese. A classic Southern starter common in Greenville restaurants.
Creamy stone-ground grits topped with shrimp, gravy, or bacon. This Lowcountry favorite is widely loved in Greenville as part of broader South Carolina cuisine.
Well-regarded neighborhood restaurant focused on seasonal Southern-influenced American cooking with a polished but relaxed atmosphere.
A long-running downtown Greenville favorite serving refined Southern cuisine in a lively, upscale setting. Known for shrimp and grits, brunch, and strong wine selections.
Popular casual spot for barbecue, ribs, and Southern comfort food near Falls Park. Lively atmosphere and a good place to try local smoked meats.
Moderate by U.S. standards: casual dining is affordable, while upscale downtown hotels and restaurants cost more.
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, hotel staff a few dollars, and round up for coffee only if desired.
Find answers to the most common questions about traveling from Greensboro, NC to Greenville, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

Most Greensboro, NC to Greenville, SC flights use the Piedmont Triad International Airport to Greenville-Spartanburg International Airport airport pair. Use this guide to compare Greensboro, NC and Greenville, SC airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Piedmont Triad International Airport is 8 km from Greensboro city centre. Public transport options include:
Piedmont Triad International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants are located in the main terminal, including fast food and sit-down options like Starbucks and PGA Tour Grill.
Free Wi-Fi available throughout the airport. ATMs are located near the baggage claim and in the main terminal.
Lost and found is available at the station.
Available at Piedmont Triad International Airport: Parking, Taxis, WC.
Available at Piedmont Triad International Airport: Car Rental.
Accessibility facilities are available at Piedmont Triad International Airport: Elevators, ramps.
Nearby hotels include Hotels like the Marriott Greensboro Airport within walking distance..
Here are some other resources that might have the information you need