- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Cheapest price on Sep 19
€192
Average ticket price on Sep 19
€192
Fastest journey on Sep 19
2 d 21 h 15 m
Average journey duration on Sep 19
2 d 21 h 15 m
Buses on Sep 19
1
Distance
3761 km
The best way to find a cheap bus ticket from Greensboro, NC to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greensboro, NC to San Francisco, CA will cost around €192 if you buy it on the day, but the cheapest tickets can be found for only €192.
On Sat, Sep 19, we found 1 buses from Greensboro, NC to San Francisco, CA, including 1 direct services.
On Sat, Sep 19 the direct buses cover the 3761 km distance in an average of 2 d 21 h 15 m but if you time it right, some buses will get you there in just 2 d 21 h 15 m .
On Sat, Sep 19 the slowest buses will take 2 d 21 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Greensboro, NC to San Francisco, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €278 For those with little time, consider booking a flight, which has an average total journey time of 9h 37m. Average ticket prices depend on the travel mode: a bus costs an average of €278, while a flight costs an average of €587.
Distance: 2336 miles (3761 km)
Most popular Bus | Flight | Driving |
|---|---|---|
€278 Average price Cheapest | €587 Average price | €461 Average price (fuel + tolls) |
64h 38m Average total duration 64h 8m Onboard + 30m Additional time* | 9h 37m Average total duration Fastest 7h 37m Onboard + 2h 0m Additional time* | 40h 37m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greensboro, NC to San Francisco, CA:
A bus is €308 less than a flight for this route with tickets for a flight from Greensboro, NC to San Francisco, CA costing on average €587.
Other travel options to San Francisco, CA take longer:
Bus takes on average 64h 8m.
Tickets start at around €278 compared to roughly €461 in fuel and tolls — a saving of about €183. The journey takes 64h 8m versus 40h 37m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:05AM | Arrival Time 05:05AM | Duration 73h00 | Departure days Fri | Cheapest price €236 |
Operator Greyhound | Departure Time 03:55PM | Arrival Time 07:10AM | Duration 66h15 | Departure days Fri | Cheapest price €228 |
Operator Greyhound | Departure Time 05:10PM | Arrival Time 12:35PM | Duration 70h25 | Departure days Fri | Cheapest price €220 |
Operator Greyhound | Departure Time 07:45PM | Arrival Time 02:15PM | Duration 66h30 | Departure days Sun | Cheapest price €194 |
Operator Greyhound | Departure Time 09:10PM | Arrival Time 07:25PM | Duration 70h15 | Departure days Mon, Tue, Wed, Sun | Cheapest price €206 |
Operator Greyhound | Departure Time 10:10PM | Arrival Time 08:25PM | Duration 70h15 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price €192 |
Operator Greyhound | Departure Time 11:05PM | Arrival Time 08:45PM | Duration 72h40 | Departure days Fri | Cheapest price €204 |
The table below shows live departures for Greensboro, NC to San Francisco, CA buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · · | 5:10 PM Greensboro, E Washington St (Greyhound Bus Station), NC | 70h25 | 12:35 PM San Francisco, Transit Center Bay 29 | 5 transfers | |
FlixBus+ · + FlixBus | 11:05 PM Greensboro, E Washington St (Greyhound Bus Station), NC | 69h50 | 5:55 PM San Francisco, Townsend Street / 5th Street, CA | 3 transfers | |
FlixBus+ · · | 11:05 PM Greensboro, E Washington St (Greyhound Bus Station), NC | 72h40 | 8:45 PM San Francisco, Transit Center Bay 29 | 4 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greensboro, NC to San Francisco, CA run on average 4 times per day, taking around 64h 8m. Cheap bus tickets for this journey start at €201 if you book in advance.
The earliest bus runs at 06:30, the last at 23:25. The fastest bus covers the 2336 miles (3761 km) distance in 60h 55m.
Distance 2336 miles (3761 km) |
Average bus duration 64h 8m |
Cheapest ticket price €201 |
Buses per day 4 |
Fastest bus 60h 55m |
First bus 6:30 AM |
Last bus 11:25 PM |
Cheapest Month Dec |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Oct - Dec |
Discover the best of San Francisco, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco, CA trip today.
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
Find answers to the most common questions about traveling from Greensboro, NC to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

Most Greensboro, NC to San Francisco, CA buses use the Greensboro, E Washington St (Greyhound Bus Station) to San Francisco, Transit Center Bay 29 station pair, with some services arriving at San Francisco, Townsend Street / 5th Street. Use this guide to compare Greensboro, NC and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greensboro, E Washington St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Greensboro, E Washington St (Greyhound Bus Station). ATMs are available at Greensboro, E Washington St (Greyhound Bus Station).
Ticket office support is available at Greensboro, E Washington St (Greyhound Bus Station).
Available at Greensboro, E Washington St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Greensboro, E Washington St (Greyhound Bus Station): Wheelchair accessible entrance and facilities available.
San Francisco, Transit Center Bay 29 is 2 km from San Francisco city centre. Public transport options include:
San Francisco, Transit Center Bay 29 has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Francisco, Transit Center Bay 29. ATMs are available at San Francisco, Transit Center Bay 29.
Ticket office support is available at San Francisco, Transit Center Bay 29.
Available at San Francisco, Transit Center Bay 29: Parking, Taxis, WC.
Accessibility facilities are available at San Francisco, Transit Center Bay 29: Wheelchair accessible areas present.
Here are some other resources that might have the information you need