- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
The best way to find a cheap bus ticket from Greensboro, NC to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greensboro, NC to San Francisco, CA will cost around $277 if you buy it on the day, but the cheapest tickets can be found for only $253.
It's difficult to get from Greensboro, NC to San Francisco, CA without transferring at least 4 times.
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Buses from Greensboro, NC to San Francisco, CA run on average 4 times per day, taking around 64h 3m. Cheap bus tickets for this journey start at $241 if you book in advance.
The earliest bus runs at 06:30, the last at 23:25. The fastest bus covers the 2336 miles (3761 km) distance in 60h 55m.
Distance 2336 miles (3761 km) |
Average bus duration 64h 3m |
Cheapest ticket price $241 |
Buses per day 4 |
Fastest bus 60h 55m |
First bus 6:30 AM |
Last bus 11:25 PM |
Cheapest Month Dec |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Oct - Dec |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Greensboro, NC to San Francisco, CA.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:05AM | Arrival Time 01:05AM | Duration 70h00 | Departure days Sat | Cheapest price $280 |
Operator Greyhound | Departure Time 04:05AM | Arrival Time 05:05AM | Duration 73h00 | Departure days Fri, Sat | Cheapest price $249 |
Operator Greyhound | Departure Time 03:45PM | Arrival Time 07:10AM | Duration 66h25 | Departure days Tue | Cheapest price $301 |
Operator Greyhound | Departure Time 05:10PM | Arrival Time 12:35PM | Duration 70h25 | Departure days Tue | Cheapest price $253 |
Operator Greyhound | Departure Time 07:45PM | Arrival Time 02:15PM | Duration 66h30 | Departure days Sun | Cheapest price $232 |
Operator Greyhound | Departure Time 09:10PM | Arrival Time 07:25PM | Duration 70h15 | Departure days Mon, Wed, Fri, Sun | Cheapest price $247 |
Operator Greyhound | Departure Time 10:10PM | Arrival Time 08:25PM | Duration 70h15 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $230 |
The table below shows live departures for Greensboro, NC to San Francisco, CA buses for tomorrow, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · · | 3:45 PM Greensboro, E Washington St (Greyhound Bus Station), NC | 66h25 | 7:10 AM San Francisco, Transit Center Bay 29 | 4 transfers | |
· · · | 5:10 PM Greensboro, E Washington St (Greyhound Bus Station), NC | 70h25 | 12:35 PM San Francisco, Transit Center Bay 29 | 5 transfers | |
This is the last bus of the day. | |||||
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Discover the best of San Francisco, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco, CA trip today.
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in San Francisco, CA.
Find answers to the most common questions about traveling from Greensboro, NC to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

Most Greensboro, NC to San Francisco, CA buses use the Greensboro, E Washington St (Greyhound Bus Station) to San Francisco, Transit Center Bay 29 station pair, with some services arriving at San Francisco, Townsend Street / 5th Street. Use this guide to compare Greensboro, NC and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greensboro, E Washington St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Greensboro, E Washington St (Greyhound Bus Station). ATMs are available at Greensboro, E Washington St (Greyhound Bus Station).
Ticket office support is available at Greensboro, E Washington St (Greyhound Bus Station).
Available at Greensboro, E Washington St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Greensboro, E Washington St (Greyhound Bus Station): Wheelchair accessible entrance and facilities available.
San Francisco, Transit Center Bay 29 is 2 km from San Francisco city centre. Public transport options include:
San Francisco, Transit Center Bay 29 has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Francisco, Transit Center Bay 29. ATMs are available at San Francisco, Transit Center Bay 29.
Ticket office support is available at San Francisco, Transit Center Bay 29.
Available at San Francisco, Transit Center Bay 29: Parking, Taxis, WC.
Accessibility facilities are available at San Francisco, Transit Center Bay 29: Wheelchair accessible areas present.
Check bus stations information for Greensboro, NC and San Francisco, CA, including where buses depart and arrive on this route.
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