- Must visit
Delaware Art Museum
Major art museum known for its Pre-Raphaelite collection, American illustration, and sculpture garden.
Cheapest price
$123
Average price
$162
Fastest journey
13 h 25 m
Average duration
13 h 25 m
Buses per day
2
Distance
722 km
The best way to find a cheap bus ticket from Florence, SC to Wilmington, DE is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Wilmington, DE will cost around $162 if you buy it on the day, but the cheapest tickets can be found for only $123.
Of the 2 buses that leave Florence, SC for Wilmington, DE on Wed, Jun 17, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jun 17 the direct buses cover the 722 km distance in an average of 13 h 25 m but if you time it right, some buses will get you there in just 13 h 25 m .
On Wed, Jun 17 the slowest buses will take 13 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from Florence, SC to Wilmington, DE among Omio's users. If you are prioritising price take the bus with prices starting from $123. For those with little time consider booking a train which can get you there in 10h 15m. The ticket price range depends on the travel mode: a bus costs an average of $123, and a train costs an average of $150.
Distance: 448 miles (722 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$182 Average price Cheapest | $193 Average price | $104 Average price (fuel + tolls) |
14h 20m Average total duration 13h 50m Onboard + 30m Additional time* | 10h 45m Average total duration Fastest 10h 15m Onboard + 30m Additional time* | 7h 42m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Florence, SC to Wilmington, DE:
A bus is $11 (€9) less than a train for this route with tickets for a train from Florence, SC to Wilmington, DE costing on average $193 (€156).
Other travel options to Wilmington, DE take longer:
Bus takes on average 13h 50m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:05AM | Arrival Time 09:50PM | Duration 16h45 | Departure days Sat | Cheapest price $172 |
Operator Greyhound USA | Departure Time 04:30PM | Arrival Time 05:55AM | Duration 13h25 | Departure days Tue, Sun | Cheapest price $119 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 09:55AM | Duration 13h25 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price $123 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 10:55AM | Duration 13h25 | Departure days Wed | Cheapest price $201 |
The table below shows live departures for Florence, SC to Wilmington, DE buses for today, Tuesday, June 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:30 PM Florence, SC | 13h25 | 5:55 AM Wilmington, DE | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Florence, SC to Wilmington, DE run on average 2 times per day, taking around 13h 50m. Cheap bus tickets for this journey start at $123 (€99) if you book in advance.
The earliest bus runs at 00:05, the last at 21:25. The fastest bus covers the 448 miles (722 km) distance in 13h 25m.
Distance 448 miles (722 km) |
Average bus duration 13h 50m |
Cheapest ticket price $123 (€99) |
Buses per day 2 |
Fastest bus 13h 25m |
First bus 12:05 AM |
Last bus 9:25 PM |
Cheapest Month Oct |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 1 day |
Discover the best of Wilmington — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Wilmington trip today.
Major art museum known for its Pre-Raphaelite collection, American illustration, and sculpture garden.
Historic industrial museum on the Brandywine, preserving the original DuPont gunpowder works and riverside estate.
Renowned museum of American decorative arts set in a grand former estate with extensive gardens.
Popular waterfront district with a riverwalk, public art, entertainment venues, and modern city views.
Large urban park with river scenery, trails, and access to the Brandywine Zoo area.
Beloved hillside park known for lawns, skyline views, and the landmark Rockford Tower.
Slow-cooked pork, often chopped or pulled, dressed in a tangy vinegar-based sauce typical of eastern North Carolina. It is one of the region’s signature foods.
A classic local barbecue sandwich made with smoky pulled pork, usually served with slaw. It is a staple at casual barbecue spots around coastal North Carolina.
Lightly battered and fried seafood, especially shrimp or fish, inspired by the nearby Calabash style of the Carolina coast. It is popular in Wilmington seafood restaurants.
Popular long-running restaurant known for Thai and Vietnamese dishes, lush decor, and a memorable garden dining atmosphere.
Well-regarded downtown restaurant focusing on North Carolina ingredients, seafood, and refined Southern cooking in a polished but relaxed setting.
Established downtown brewpub serving house beer and crowd-pleasing American food in a lively historic space.
Costs are moderate by U.S. standards. Casual dining is affordable, while hotels and fine dining can be pricier in peak periods.
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Florence, SC to Wilmington, DE by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Wilmington, DE, this guide helps you travel smarter and with confidence.

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