Travel Information
Compare train and bus for Florence, SC to Wilmington, DE
Omio recommends booking the train as it is the most popular option from Florence, SC to Wilmington, DE among Omio's users. If you are prioritising price take the bus with prices starting from €52. For those with little time consider booking a train which can get you there in 10h 12m. The ticket price range depends on the travel mode: a bus costs an average of €52, and a train costs an average of €98.
Distance: 448 miles (722 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€57 Average price Cheapest | €98 Average price |
14h 10m Average total duration 13h 40m Onboard + 30m Additional time* | 10h 42m Average total duration Fastest 10h 12m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Florence, SC to Wilmington, DE bus times
The table below shows live departures for Florence, SC to Wilmington, DE buses for today, Sunday, November 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:15 PM Florence, SC | 13h40 | 9:55 AM Wilmington, DE | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Compare prices and tickets Florence, SC to Wilmington, DE by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Florence, SC to Wilmington, DE
Buses from Florence, SC to Wilmington, DE run on average 2 times per day, taking around 13h 40m. Cheap bus tickets for this journey start at $64 (€52) if you book in advance.
The earliest bus runs at 12:25, the last at 21:25. The fastest bus covers the 448 miles (722 km) distance in 13h 40m.
Distance 448 miles (722 km) |
Average bus duration 13h 40m |
Cheapest ticket price $64 (€52) |
Buses per day 2 |
Fastest bus 13h 40m |
First bus 12:25 |
Last bus 21:25 |
FAQs: Bus from Florence, SC to Wilmington, DE
Find answers to the most common questions about traveling from Florence, SC to Wilmington, DE by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Wilmington, DE, this guide helps you travel smarter and with confidence.

- Nemours Estate, a grand 300-acre estate featuring formal French gardens and a classical mansion
- Hagley Museum and Library, a historical site showcasing the early American industrial revolution with exhibits and scenic grounds
- Delaware Art Museum, home to a diverse collection of American art and illustration, including works by the Brandywine School
- Brandywine Zoo, a small zoo located in Brandywine Park featuring a variety of animals and educational programs
- Rockford Park, a historic park offering scenic views, walking trails, and the iconic Rockford Tower.
- Riverfront Wilmington, a vibrant area with dining, shopping, and scenic views along the Christina River
- Wilmington and Western Railroad, offering scenic train rides through the picturesque countryside
- The Grand Opera House, a historic venue hosting a variety of performances and events
- Delaware Children's Museum, an interactive museum with engaging exhibits for kids
- Alapocas Run State Park, perfect for hiking, rock climbing, and enjoying nature.
To find the cheapest bus tickets for your trip from Florence, SC to Wilmington, DE, follow these tips:
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popular bus stations
Popular bus stations from Florence, SC to Wilmington, DE
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