- Must visit
Delaware Art Museum
Top regional museum with outstanding American art, British Pre-Raphaelite works, and a serene riverside setting in downtown Wilmington.
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The cheapest and fastest buses from Florence, SC to Wilmington, DE
Showing times, prices and bookable tickets for Sep 17
Cheapest price on Sep 17
$92
Average ticket price on Sep 17
$92
Fastest journey on Sep 17
1 d 10 m
Average journey duration on Sep 17
1 d 10 m
Buses on Sep 17
1
Distance
722 km
Cheap tickets
The best way to find a cheap bus ticket from Florence, SC to Wilmington, DE is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Wilmington, DE will cost around $92 if you buy it on the day, but the cheapest tickets can be found for only $92.
Fast buses
It's difficult to get from Florence, SC to Wilmington, DE without transferring at least 3 times.
FlixBus+
+FlixBus+5:45 AM24h10Florence, W Lucas St (TA Gas Station), SC5:55 AMWilmington, Amtrak Station @ ML King-French$921One-way3 transfers
- FlixBus++FlixBus+5:45 AM24h10Florence, W Lucas St (TA Gas Station), SC5:55 AMWilmington, Amtrak Station @ ML King-French$921One-way3 transfers
Travel Information
Compare train and bus for Florence, SC to Wilmington, DE
Omio recommends booking the train as it is the most popular option from Florence, SC to Wilmington, DE among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $157 For those with little time, consider booking a flight, which has an average total journey time of 5h 45m. Average ticket prices depend on the travel mode: a bus costs an average of $157, while a flight costs an average of $844.
Distance: 448 miles (722 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$157 Average price Cheapest | $252 Average price | $844 Average price | $105 Average price (fuel + tolls) |
11h 47m Average total duration 11h 17m Onboard + 30m Additional time* | 10h 31m Average total duration 10h 1m Onboard + 30m Additional time* | 5h 45m Average total duration Fastest 3h 45m Onboard + 2h 0m Additional time* | 7h 42m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Florence, SC to Wilmington, DE is a bus with an average price of $157.
This is compared to other travel options from Florence, SC to Wilmington, DE:
A bus is $86 less than a train for this route with tickets for a train from Florence, SC to Wilmington, DE costing on average $243.
A bus is $688 less than a flight for this route with tickets for a flight from Florence, SC to Wilmington, DE costing on average $844.
The fastest way to travel from Florence, SC to Wilmington, DE is by flight with an average journey time of 3h 45m.
Other travel options to Wilmington, DE take longer:
Train takes on average 10h 7m.
Bus takes on average 11h 17m.
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Wilmington, DE including taking a train and bus.
We recommend using the train as it is the most popular way to get from Florence, SC to Wilmington, DE among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $157 compared to roughly $105 in fuel and tolls — a saving of about $-51.46. The journey takes 11h 17m versus 7h 42m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Florence, SC to Wilmington, DE Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05AM | Arrival Time 01:40PM | Duration 13h35 | Departure days Fri | Cheapest price $95 |
Operator FlixBus | Departure Time 05:05AM | Arrival Time 09:50PM | Duration 16h45 | Departure days Sat | Cheapest price $171 |
Operator FlixBus | Departure Time 05:45AM | Arrival Time 05:55AM | Duration 24h10 | Departure days Thu, Fri | Cheapest price $77 |
Operator Greyhound USA | Departure Time 04:30PM | Arrival Time 05:55AM | Duration 13h25 | Departure days Tue, Sun | Cheapest price $118 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 09:55AM | Duration 13h25 | Departure days Mon, Wed, Sat | Cheapest price $122 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 10:55AM | Duration 13h25 | Departure days Wed | Cheapest price $200 |
Live departures
Florence, SC to Wilmington, DE bus times
The table below shows live departures for Florence, SC to Wilmington, DE buses for today, Wednesday, September 16. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 8:30 PM Florence, SC | 13h25 | 9:55 AM Wilmington, DE | 0 transfersDirect | |
| 9:30 PM Florence, SC | 13h25 | 10:55 AM Wilmington, DE | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Wilmington, DE by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Florence, SC to Wilmington, DE buses with Omio?
FlixBus operates all buses services from Florence, SC to Wilmington, DE.
Omio is an official ticket reseller for all your travel options from Florence, SC to Wilmington, DE.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Florence, SC to Wilmington, DE.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Florence, SC to Wilmington, DE.
Journey information
Overview: Bus from Florence, SC to Wilmington, DE
USAUSA
Buses from Florence, SC to Wilmington, DE run on average 1 times per day, taking around 11h 17m. Cheap bus tickets for this journey start at $96 if you book in advance.
The earliest bus runs at 00:05, the last at 21:25. The fastest bus covers the 448 miles (722 km) distance in 10h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 448 miles (722 km) |
Average bus duration 11h 17m |
Cheapest ticket price $96 |
Buses per day 1 |
Fastest bus 10h 30m |
First bus 12:05 AM |
Last bus 9:25 PM |
Cheapest Month Oct |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 1 day |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus from Florence, SC to Wilmington, DEYou can travel by bus between Florence, SC to Wilmington, DE with FlixBus for as low as $96. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
10h 30m
Cheapest FlixBus Price
$96
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Wilmington, DE
Things to do in Wilmington, DE
Discover the best of Wilmington, DE — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Wilmington, DE trip today.
- Must visit
Winterthur Museum, Garden & Library
Major decorative arts museum in a grand du Pont estate. Period rooms, gardens, and research collections make it one of Delaware’s essential visits.
- Must visit
Hagley Museum and Library
Industrial history museum on the Brandywine at the original du Pont gunpowder works. It blends river scenery, engineering, and family history.
- Must visit
Wilmington Riverfront
Revitalized riverfront district with paths, public art, mini golf, and event spaces. It is one of Wilmington’s most popular areas for walking and views.
- Must visit
Brandywine Park
Large urban park with lawns, trails, gardens, and creek views. It is a favorite local green space beside major museums and historic sites.
- Recommended
Rodney Square
Major downtown square framed by historic buildings, offices, and monuments. It is the city’s classic civic center and an easy orientation point.
Scrapple
Scrapple is a Mid-Atlantic breakfast loaf of pork scraps and cornmeal, sliced and fried crisp. It is a Delaware staple found in many local diners.
Blue Crab Cakes
Blue crab cakes are common along the Delaware coast and nearby bay waters, prized for sweet lump crab with minimal filler and regional seafood tradition.
- Vegetarian
- Vegan
- Gluten-free
Boardwalk Fries
Boardwalk fries are hand-cut fries served hot with salt and vinegar. They are a beloved Delaware beach snack strongly associated with nearby coastal outings.
Bardea Food & Drink
Refined Italian restaurant known for house-made pasta, seasonal ingredients, and polished service in an elegant downtown setting.
The Green Room
Historic fine-dining destination serving contemporary American cuisine with strong wine service in a grand, stately atmosphere.
Lucky's Coffee Shop
Classic Delaware diner famous for scrapple, hearty breakfasts, and old-school local comfort food in a casual setting.
United States dollar ($)
Moderate for U.S. city trips; hotels and dining are mid-priced, while transit and parking are manageable versus larger East Coast destinations.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.
FAQs: Bus from Florence, SC to Wilmington, DE
Find answers to the most common questions about traveling from Florence, SC to Wilmington, DE by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Wilmington, DE, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Florence, SC to Wilmington, DE can start from as little as $96 when you book in advance. The average bus ticket price for Florence, SC to Wilmington, DE is $157 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Florence, SC to Wilmington, DE is 10h 30m to travel the 448 miles (722 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Florence, SC to Wilmington, DE leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Wilmington, DE leaves at 9:25 PM.
There are 1 buses a day from Florence, SC to Wilmington, DE which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Florence, SC to Wilmington, DE, you can count on FlixBus for the best way to get you to Wilmington, DE. You can also check all possible bus companies who offer a service between Florence, SC and Wilmington, DE and compare the amenities they offer before buying a bus ticket.
A trip to Wilmington, DE from Florence, SC is worth doing but not as a day trip with a journey time of 10h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Florence, SC to Wilmington, DE is October.
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Wilmington, DE including taking a train and bus.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Wilmington, DE:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Florence, SC to Wilmington, DE for bus company FlixBus.
Some of the most interesting sights to explore in Wilmington, DE are:
- Nemours Estate, a grand 300-acre estate featuring formal French gardens and a classical mansion
- Hagley Museum and Library, a historical site showcasing the early American industrial revolution with exhibits and scenic grounds
- Delaware Art Museum, home to a diverse collection of American art and illustration, including works by the Brandywine School
- Brandywine Zoo, a small zoo located in Brandywine Park featuring a variety of animals and educational programs
- Rockford Park, a historic park offering scenic views, walking trails, and the iconic Rockford Tower.
The best things to do in Wilmington, DE include:
- Riverfront Wilmington, a vibrant area with dining, shopping, and scenic views along the Christina River
- Wilmington and Western Railroad, offering scenic train rides through the picturesque countryside
- The Grand Opera House, a historic venue hosting a variety of performances and events
- Delaware Children's Museum, an interactive museum with engaging exhibits for kids
- Alapocas Run State Park, perfect for hiking, rock climbing, and enjoying nature.
Whether you can cancel your bus ticket from Florence, SC to Wilmington, DE depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Florence, SC to Wilmington, DE.
Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Wilmington, DE:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Wilmington, DE:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Florence, SC to Wilmington, DE. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Florence, SC to Wilmington, DE with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Florence, SC to Wilmington, DE with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Florence, SC to Wilmington, DE with the following bus company: FlixBus.
Since neither Florence, SC nor Wilmington, DE are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Florence, SC to Wilmington, DE among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Wilmington, DE, travelers should be cautious of petty theft, such as pickpocketing, especially in crowded areas and public transportation. It's advised to avoid poorly lit or isolated neighborhoods at night. Common scams include overcharging by unofficial taxi services and fraudulent ticket sellers. Staying alert and using licensed transportation options can help ensure a safer visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Florence, SC to Wilmington, DE
Most Florence, SC to Wilmington, DE buses use the Florence, S Irby St (Greyhound Bus Stop) to Wilmington, Amtrak Station @ ML King-French station pair. Use this guide to compare Florence, SC and Wilmington, DE bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Florence
Arrival bus stations in Wilmington
Which Florence, SC station do buses to Wilmington, DE leave from?
Buses from Florence, SC to Wilmington, DE leave from Florence, W Lucas St (TA Gas Station). The station is 3 miles (6 km) from Florence, SC city centre at Florence, SC, USA.
Florence, S Irby St (Greyhound Bus Stop)S Irby St, Florence, SC, USA
City-centre transport
Getting to Florence, S Irby St (Greyhound Bus Stop) from Florence city centre
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Florence, S Irby St (Greyhound Bus Stop) bus station facilities and services
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Tickets and information
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Parking, taxis and toilets
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
Florence, W Lucas St (TA Gas Station)Florence, SC, USA
City-centre transport
Getting to Florence, W Lucas St (TA Gas Station) from Florence city centre
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
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Florence, W Lucas St (TA Gas Station) bus station facilities and services
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Food and snacks available at the gas station.
Wi-Fi and ATMs
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Tickets and information
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Parking, taxis and toilets
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
Wilmington, Amtrak Station @ ML King-French
City-centre transport
Getting to Wilmington, Amtrak Station @ ML King-French from Wilmington city centre
Bus002, 006, 035 · 4m · $2 · every ~9 min
013, 020 · 4m · $2 · every ~5 min
Most popular bus connections from Florence, SC
More options for your journey from Florence, SC to Wilmington, DE
Here are some other resources that might have the information you need
Most popular buses to and from Wilmington, DE and Florence, SC
Most popular bus connections to Wilmington, DE
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