- Must visit
National Civil Rights Museum
Major museum at the former Lorraine Motel, tracing the American civil rights movement and the legacy of Dr. Martin Luther King Jr. One of Memphis’s most important cultural sites.
Omio recommends booking the bus as it is the most popular option from Florence, SC to Memphis, TN among Omio's users. If you are prioritising price take the bus with prices starting from $90. For those with little time consider booking a bus which can get you there in 18h 56m. The ticket price range depends on the travel mode: a bus costs an average of $90, and a train costs an average of $352.
Distance: 587 miles (946 km)
Most popular Bus | Train | Driving |
|---|---|---|
$92 Average price Cheapest | $366 Average price | $135 Average price (fuel + tolls) |
19h 26m Average total duration Fastest 18h 56m Onboard + 30m Additional time* | 57h 40m Average total duration 57h 10m Onboard + 30m Additional time* | 10h 2m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Florence, SC to Memphis, TN:
A bus is $274 (€224) less than a train for this route with tickets for a train from Florence, SC to Memphis, TN costing on average $366 (€299).
Other travel options to Memphis, TN take longer:
Train takes on average 57h 10m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 04:10PM | Arrival Time 09:00AM | Duration 16h50 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $191 |
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Florence, SC to Memphis, TN run on average 3 times per day, taking around 18h 56m. Cheap bus tickets for this journey start at $90 (€73) if you book in advance.
The earliest bus runs at 00:15, the last at 22:45. The fastest bus covers the 587 miles (946 km) distance in 16h 15m.
Distance 587 miles (946 km) |
Average bus duration 18h 56m |
Cheapest ticket price $90 (€73) |
Buses per day 3 |
Fastest bus 16h 15m |
First bus 12:15 AM |
Last bus 10:45 PM |
Cheapest Month Jun |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Apr - Jun |
Discover the best of Memphis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Memphis trip today.
Major museum at the former Lorraine Motel, tracing the American civil rights movement and the legacy of Dr. Martin Luther King Jr. One of Memphis’s most important cultural sites.
Museum on the original Stax Records site, celebrating soul music legends and the label’s deep connection to Memphis. A favorite for music fans and culture-focused visitors.
Smithsonian-affiliated museum telling the story of Memphis music, from rural roots to the rise of rock and soul. Compact, well-curated, and easy to pair with Beale Street.
Memphis’s most famous entertainment street, known for live music, neon signs, and deep blues heritage. A core stop for first-time visitors day or night.
Walkable downtown district with galleries, restored buildings, murals, and a more local feel than Beale Street. Popular for photography and casual exploring.
Huge urban park with lakes, trails, open space, and outdoor recreation. One of the best green spaces in Memphis for families, walkers, and cyclists.
Slow-smoked pork ribs, usually served dry-rubbed or lightly sauced. They are one of Memphis’s signature barbecue specialties.
Chopped or pulled smoked pork piled on a bun, often topped with slaw. It is a classic everyday Memphis barbecue order.
Memphis barbecue famous for a spice rub applied before smoking rather than heavy sauce. It highlights the city’s pit-smoking tradition.
Established upscale downtown restaurant offering tasting flights, refined New American dishes, and a polished atmosphere.
Beloved local barbecue spot celebrated for ribs, pulled pork, and barbecue spaghetti in an unfussy traditional atmosphere.
Popular long-running barbecue restaurant known for Memphis-style ribs, pulled pork, and smoked wings in a lively casual setting.
Moderate by U.S. standards. Hotels and dining are often cheaper than in larger coastal cities, though tourist areas and live music venues cost more.
Tip 18-20% at restaurants; 20%+ for great service. Tip USD 1-2 per drink at bars, round up taxis or tip 10-15%, and tip hotel staff and valet.
Find answers to the most common questions about traveling from Florence, SC to Memphis, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Memphis, TN, this guide helps you travel smarter and with confidence.

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