Florence, SC to Harrisburg, PA bus with Southeastern Stages

Wed, Nov 05
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Southeastern Stages
FlixBus
Alsa
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Rede Expressos
1,000+ travel companies
Southeastern Stages
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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The cheapest and fastest buses from Florence, SC to Harrisburg, PA

Showing times and prices for Nov 06

Cheapest price

$284

Average price

$284

Fastest journey

1 d 6 h 20 m

Average duration

1 d 6 h 20 m

Buses per day

1

Distance

722 km

Cheap tickets

The best way to find a cheap bus ticket from Florence, SC to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Florence, SC to Harrisburg, PA will cost around $284 if you buy it on the day, but the cheapest tickets can be found for only $284.

Fast buses

It's difficult to get from Florence, SC to Harrisburg, PA without transferring at least 2 times.

Southeastern Stages
02:25PM30h20
Florence, SC
08:45PMHarrisburg, PA
$2841One-way
2 transfers

Travel Information

Compare train and bus for Florence, SC to Harrisburg, PA

Omio recommends booking the train as it is the most popular option from Florence, SC to Harrisburg, PA among Omio's users. If you are prioritising price take the bus with prices starting from €85. For those with little time consider booking a train which can get you there in 12h 9m. The ticket price range depends on the travel mode: a bus costs an average of €85, and a train costs an average of €222.

Distance: 448 miles (722 km)

Compare bus with

Bus
Most popular
Train

€85

Average price

Cheapest

€222

Average price

22h 50m

Average total duration

22h 20m

Onboard

+

30m

Additional time*

12h 39m

Average total duration

Fastest

12h 9m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Live departures

Florence, SC to Harrisburg, PA bus times

The table below shows live departures for Florence, SC to Harrisburg, PA buses for today, Wednesday, November 5. You can also manually refresh the results below to see updated bus journeys.

Last updated at 10:31 AM

ProviderDepartsDurationArrivesTransfers
Tickets
Southeastern Stages2:25 PM Florence, SC
30h20
8:45 PM Harrisburg, PA2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Florence, SC to Harrisburg, PA by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
Nov 06
Fri
Nov 07
Sat
Nov 08
Sun
Nov 09
Mon
Nov 10
Tue
Nov 11
Wed
Nov 12

Journey information

Overview: Bus from Florence, SC to Harrisburg, PA

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Buses from Florence, SC to Harrisburg, PA run on average 1 times per day, taking around 22h 20m. Cheap bus tickets for this journey start at $104 (€85) if you book in advance.
The earliest bus runs at 00:05, the last at 23:20. The fastest bus covers the 448 miles (722 km) distance in 22h 20m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
448 miles (722 km)
Average bus duration
22h 20m
Cheapest ticket price
$104 (€85)
Buses per day
1
Fastest bus
22h 20m
First bus
00:05
Last bus
23:20
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Southeastern Stages from Florence, SC to Harrisburg, PAYou can travel by bus between Florence, SC to Harrisburg, PA with Southeastern Stages for as low as $104 (€85). When you search for schedules and tickets, Omio will show you the best journey

Southeastern Stages

Luggage & cancellation policy
Average Duration
30h 20m
Cheapest Price
$273 (€223)
Southeastern Stages frequency
1 a day

FAQs: Bus from Florence, SC to Harrisburg, PA

Find answers to the most common questions about traveling from Florence, SC to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.
FAQs
Cheap bus tickets from Florence, SC to Harrisburg, PA can start from as little as $310 (€253) when you book in advance. The average bus ticket price for Florence, SC to Harrisburg, PA is $320 (€261); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The bus time to Harrisburg, PA from Florence, SC is on average 30 h 20 min   for the 448 mile (722 km) long journey, but the time it takes to go between Florence, SC and Harrisburg, PA by bus can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Florence, SC to Harrisburg, PA leaves at 8: 35AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Florence, SC to Harrisburg, PA leaves at 11: 20PM.
There is 1 bus a day from Florence, SC to Harrisburg, PA which require at least one change with Southeastern Stages. Schedules can vary on holidays or weekends with fewer buses.
For the trip from Florence, SC to Harrisburg, PA you can take a bus with Southeastern Stages. Be sure to check out all possible bus providers that offer services between Florence, SC and Harrisburg, PA on Omio to compare what amenities they may have.
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Harrisburg, PA including taking a train or bus.
No, the bus from Florence, SC to Harrisburg, PA has no accessibility options.
No, there are no bathrooms on board the bus from Florence, SC to Harrisburg, PA.
Some of the most interesting sights to explore in Harrisburg, PA are:
  • Pennsylvania State Capitol, an architectural marvel featuring a grand dome and exquisite interior murals
  • National Civil War Museum, a comprehensive museum offering insights into the American Civil War with extensive exhibits
  • The State Museum of Pennsylvania, showcasing the state's history, art, and natural sciences through diverse collections
  • Fort Hunter Mansion and Park, a historic site with preserved buildings and beautiful grounds reflecting 18th and 19th-century life
  • Wildwood Park, a nature preserve offering trails and a nature center for wildlife observation and environmental education.
The best things to do in Harrisburg, PA include:
  • City Island, a recreational area featuring sports facilities, walking trails, and riverboat cruises
  • Whitaker Center for Science and the Arts, a venue offering interactive science exhibits and live performances
  • Broad Street Market, one of the oldest continuously operating farmers' markets in the country, offering diverse local foods and goods
  • Susquehanna Art Museum, presenting contemporary art exhibitions and educational programs
  • Riverfront Park, ideal for walking, biking, and enjoying views of the Susquehanna River.
No, bikes are not allowed on board the bus from Florence, SC to Harrisburg, PA.

To find the cheapest bus tickets for your trip from Florence, SC to Harrisburg, PA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Florence, SC to Harrisburg, PA.
    No, luggage for the bus from Florence, SC to Harrisburg, PA needs to be booked in addition.
    No, there are no additional luggage options for the bus from Florence, SC to Harrisburg, PA.
    Unfortunately, pets are not allowed on the bus from Florence, SC to Harrisburg, PA.
    No, there are no USB plugs on board the bus from Florence, SC to Harrisburg, PA.
    No, there is no WiFi on board the bus from Florence, SC to Harrisburg, PA.

    popular bus stations

    Popular bus stations from Florence, SC to Harrisburg, PA

    Florence
    Harrisburg
    The major bus station for departures in Florence is Florence, S Irby St (Greyhound Bus Stop). Find all the information you need to know about services, amenities and connections at Florence, S Irby St (Greyhound Bus Stop) for your trip from Florence to Harrisburg.
    Florence, S Irby St (Greyhound Bus Stop)
    information

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