Florence, SC to Harrisburg, PA bus with Southeastern Stages

Sat, Mar 21
+ Add return
Southeastern Stages
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Alsa
Costa Verde
BlaBlaCar Bus
2,000+ travel companies
Southeastern Stages
FlixBus
Alsa
Costa Verde
BlaBlaCar Bus
2,000+ travel companies
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The cheapest and fastest buses from Florence, SC to Harrisburg, PA

Showing times and prices for Mar 22

Cheapest price

$185

Average price

$185

Fastest journey

21 h 25 m

Average duration

21 h 25 m

Buses per day

1

Distance

722 km

Cheap tickets

The best way to find a cheap bus ticket from Florence, SC to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Florence, SC to Harrisburg, PA will cost around $185 if you buy it on the day, but the cheapest tickets can be found for only $185.

Fast buses

Of the 1 buses that leave Florence, SC for Harrisburg, PA on Sun, Mar 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Sun, Mar 22 the direct buses cover the 722 km distance in an average of 21 h 25 m but if you time it right, some buses will get you there in just 21 h 25 m .

On Sun, Mar 22 the slowest buses will take 21 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Greyhound
09:30PM21h25
Florence, SC
06:55PMHarrisburg, PA
$1851One-way
0 transfers

Travel Information

Compare train and bus for Florence, SC to Harrisburg, PA

Omio recommends booking the train as it is the most popular option from Florence, SC to Harrisburg, PA among Omio's users. If you are prioritising price take the bus with prices starting from $122. For those with little time consider booking a train which can get you there in 12h 9m. The ticket price range depends on the travel mode: a bus costs an average of $122, and a train costs an average of $171.

Distance: 448 miles (722 km)

Compare bus with

Bus
Most popular
Train

$185

Average price

Cheapest

$189

Average price

21h 55m

Average total duration

21h 25m

Onboard

+

30m

Additional time*

12h 39m

Average total duration

Fastest

12h 9m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Compare prices and tickets Florence, SC to Harrisburg, PA by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Mar 22
Mon
Mar 23
Tue
Mar 24
Wed
Mar 25
Thu
Mar 26
Fri
Mar 27
Sat
Mar 28

Journey information

Overview: Bus from Florence, SC to Harrisburg, PA

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Buses from Florence, SC to Harrisburg, PA run on average 1 times per day, taking around 21h 25m. Cheap bus tickets for this journey start at $122 (€98) if you book in advance.

The earliest bus runs at 00:05, the last at 23:20. The fastest bus covers the 448 miles (722 km) distance in 21h 25m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
448 miles (722 km)
Average bus duration
21h 25m
Cheapest ticket price
$122 (€98)
Buses per day
1
Fastest bus
21h 25m
First bus
00:05
Last bus
23:20
Cheapest month
Sep
Cheapest day
Tue
High season
Jan - Mar
Low season
Oct - Dec
Best day to book ahead
2 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Southeastern Stages from Florence, SC to Harrisburg, PAYou can travel by bus between Florence, SC to Harrisburg, PA with Southeastern Stages for as low as $122 (€98). When you search for schedules and tickets, Omio will show you the best journey

Southeastern Stages

Luggage & cancellation policy
Average Duration
30h 20m
Cheapest Price
$273 (€221)
Southeastern Stages frequency
1 a day

FAQs: Bus from Florence, SC to Harrisburg, PA

Find answers to the most common questions about traveling from Florence, SC to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Florence, SC to Harrisburg, PA can start from as little as $122 (€98) when you book in advance. The average bus ticket price for Florence, SC to Harrisburg, PA is $185 (€150) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Florence, SC to Harrisburg, PA is 21h 25m to travel the 448 miles (722 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Florence, SC to Harrisburg, PA leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Harrisburg, PA leaves at 11:20 PM.
There are 1 buses a day from Florence, SC to Harrisburg, PA which require at least one change with Southeastern Stages. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Florence, SC to Harrisburg, PA, you can count on Southeastern Stages for the best way to get you to Harrisburg, PA. You can also check all possible bus companies who offer a service between Florence, SC and Harrisburg, PA and compare the amenities they offer before buying a bus ticket.
A trip to Harrisburg, PA from Florence, SC is worth doing but not as a day trip with a journey time of 21h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Florence, SC to Harrisburg, PA is September.
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Harrisburg, PA including taking a train and bus.
No, the bus from Florence, SC to Harrisburg, PA has no accessibility options.
No, there are no bathrooms on board the bus from Florence, SC to Harrisburg, PA.
Some of the most interesting sights to explore in Harrisburg, PA are:
  • Pennsylvania State Capitol, an architectural marvel featuring a grand dome and exquisite interior murals
  • National Civil War Museum, a comprehensive museum offering insights into the American Civil War with extensive exhibits
  • The State Museum of Pennsylvania, showcasing the state's history, art, and natural sciences through diverse collections
  • Fort Hunter Mansion and Park, a historic site with preserved buildings and beautiful grounds reflecting 18th and 19th-century life
  • Wildwood Park, a nature preserve offering trails and a nature center for wildlife observation and environmental education.
The best things to do in Harrisburg, PA include:
  • City Island, a recreational area featuring sports facilities, walking trails, and riverboat cruises
  • Whitaker Center for Science and the Arts, a venue offering interactive science exhibits and live performances
  • Broad Street Market, one of the oldest continuously operating farmers' markets in the country, offering diverse local foods and goods
  • Susquehanna Art Museum, presenting contemporary art exhibitions and educational programs
  • Riverfront Park, ideal for walking, biking, and enjoying views of the Susquehanna River.
No, bikes are not allowed on board the bus from Florence, SC to Harrisburg, PA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Florence, SC to Harrisburg, PA.
No, luggage for the bus from Florence, SC to Harrisburg, PA needs to be booked in addition.
No, there are no additional luggage options for the bus from Florence, SC to Harrisburg, PA.
Unfortunately, pets are not allowed on the bus from Florence, SC to Harrisburg, PA.
No, there are no USB plugs on board the bus from Florence, SC to Harrisburg, PA.
No, there is no WiFi on board the bus from Florence, SC to Harrisburg, PA.

popular bus stations

Popular bus stations from Florence, SC to Harrisburg, PA

Florence
Harrisburg
The major bus station for departures in Florence is Florence, S Irby St (Greyhound Bus Stop). Find all the information you need to know about services, amenities and connections at Florence, S Irby St (Greyhound Bus Stop) for your trip from Florence to Harrisburg.
Florence, S Irby St (Greyhound Bus Stop)
information

Most popular bus connections from Florence, SC

More options for your journey from Florence, SC to Harrisburg, PA

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