- Must visit
The State Museum of Pennsylvania
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
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The cheapest and fastest buses from Florence, SC to Harrisburg, PA
Showing times and prices for Aug 05
Cheapest price
zł766
Average price
zł795
Fastest journey
21 h 25 m
Average duration
21 h 25 m
Buses per day
2
Distance
722 km
Cheap tickets
The best way to find a cheap bus ticket from Florence, SC to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Harrisburg, PA will cost around zł795 if you buy it on the day, but the cheapest tickets can be found for only zł766.
Fast buses
Of the 2 buses that leave Florence, SC for Harrisburg, PA on Wed, Aug 05, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct buses cover the 722 km distance in an average of 21 h 25 m but if you time it right, some buses will get you there in just 21 h 25 m .
On Wed, Aug 05 the slowest buses will take 21 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
9:30 PM21h25Florence, SC6:55 PMHarrisburg, PAzł7661One-way0 transfers- 8:30 PM21h25Florence, SC5:55 PMHarrisburg, PAzł8241One-way0 transfers
- 9:30 PM21h25Florence, SC6:55 PMHarrisburg, PAzł7661One-way0 transfers
- 8:30 PM21h25Florence, SC5:55 PMHarrisburg, PAzł8241One-way0 transfers
Journey information
Overview: Bus from Florence, SC to Harrisburg, PA
USAUSA
Buses from Florence, SC to Harrisburg, PA run on average 1 times per day, taking around 21h 25m. Cheap bus tickets for this journey start at zł453 if you book in advance.
The earliest bus runs at 00:05, the last at 23:20. The fastest bus covers the 448 miles (722 km) distance in 21h 25m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 448 miles (722 km) |
Average bus duration 21h 25m |
Cheapest ticket price zł453 |
Buses per day 1 |
Fastest bus 21h 25m |
First bus 12:05 AM |
Last bus 11:20 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 2 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Florence, SC to Harrisburg, PA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05AM | Arrival Time 01:55PM | Duration 13h50 | Departure days Tue | Cheapest price zł593 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 05:55PM | Duration 21h25 | Departure days Wed, Thu, Fri, Sat | Cheapest price zł567 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 06:55PM | Duration 21h25 | Departure days Mon, Wed, Thu, Sun | Cheapest price zł453 |
Why should you book Florence, SC to Harrisburg, PA buses with Omio?
Greyhound operates all buses services from Florence, SC to Harrisburg, PA.
Omio is an official ticket reseller for all your travel options from Florence, SC to Harrisburg, PA.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and train to ensure you get the best deal for traveling from Florence, SC to Harrisburg, PA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Florence, SC to Harrisburg, PA.
Bus providers: Greyhound from Florence, SC to Harrisburg, PAYou can travel by bus between Florence, SC to Harrisburg, PA with Greyhound for as low as zł453. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
21h 25m
Cheapest Price
zł453
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Harrisburg, PA
Things to do in Harrisburg, PA
Discover the best of Harrisburg, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg, PA trip today.
- Must visit
National Civil War Museum
National Civil War museum with broad exhibits on soldiers, civilians, and the war's legacy. It is one of the city's most important history stops.
- Recommended
Fort Hunter Mansion and Park Museum
Museum at Fort Hunter highlighting local river history, mansion life, and the Susquehanna landscape. A quieter favorite with a scenic setting.
- Must visit
Riverfront Park
Riverfront promenade and park system with skyline views, paths, and event spaces. It is one of the most pleasant walks in central Harrisburg.
- Recommended
City Island
Car-free island in the Susquehanna with walking paths, recreation, and broad water views. A classic local escape close to downtown.
- Recommended
Midtown
Victorian neighborhood known for colorful homes, local shops, and a creative atmosphere. It is ideal for strolling and seeing everyday Harrisburg charm.
Pennsylvania Dutch Chicken Pot Pie
Pennsylvania Dutch chicken pot pie is a rich stew with square noodles, chicken, and vegetables. It is a regional comfort food common around Harrisburg.
- Vegetarian
Shoofly Pie
Shoofly pie is a classic Pennsylvania Dutch dessert made with molasses crumb filling. Its deep sweetness makes it a traditional local bakery staple.
- Vegetarian
Whoopie Pie
Whoopie pie features two soft chocolate cake rounds with creamy filling. It is a beloved Amish and Pennsylvania Dutch treat found across the region.
Rubicon
Long-running local favorite serving creative American dishes and seafood in a comfortable, polished neighborhood setting.
Broad Street Market
Historic market with many established local vendors for Pennsylvania Dutch baked goods, pretzels, sandwiches, and regional specialties in a lively setting.
Zeroday Brewing Company
Popular casual tavern and brewery pouring local beer with pub fare. It is well known for a relaxed atmosphere and central location.
US dollar ($)
Moderate for US state capitals; hotels and dining are usually below major East Coast cities, while transit needs and limited cheap tourist areas can raise daily costs.
Average meal costs
- Budget
- $10-15 for fast food or a simple lunch.
- Mid-range
- $18-35 per person for a casual restaurant meal.
- Fine dining
- $50+ per person for upscale dining.
- Coffee
- $3-5 for coffee or a cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
FAQs: Bus from Florence, SC to Harrisburg, PA
Find answers to the most common questions about traveling from Florence, SC to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Florence, SC to Harrisburg, PA can start from as little as zł453 when you book in advance. The average bus ticket price for Florence, SC to Harrisburg, PA is zł704 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Florence, SC to Harrisburg, PA is 21h 25m to travel the 448 miles (722 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Florence, SC to Harrisburg, PA leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Harrisburg, PA leaves at 11:20 PM.
There are 1 buses a day from Florence, SC to Harrisburg, PA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Florence, SC to Harrisburg, PA, you can count on Greyhound for the best way to get you to Harrisburg, PA. You can also check all possible bus companies who offer a service between Florence, SC and Harrisburg, PA and compare the amenities they offer before buying a bus ticket.
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Harrisburg, PA including taking a bus and train.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Harrisburg, PA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Florence, SC to Harrisburg, PA for bus company Greyhound.
Whether you can cancel your bus ticket from Florence, SC to Harrisburg, PA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Florence, SC to Harrisburg, PA.
Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Harrisburg, PA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Harrisburg, PA:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Florence, SC to Harrisburg, PA.
You can reserve your seat on the bus from Florence, SC to Harrisburg, PA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Florence, SC to Harrisburg, PA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Florence, SC to Harrisburg, PA with the following bus company: Greyhound.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Harrisburg, PA, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Common scams include overpriced taxi services and fraudulent ticket sellers near popular attractions. Staying aware of surroundings and using authorized transportation options helps enhance safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Florence, SC to Harrisburg, PA
Most Florence, SC to Harrisburg, PA buses use the Florence, S Irby St (Greyhound Bus Stop) to Harrisburg, Market St (Bus Station) station pair, with some services arriving at Harrisburg, Chestnut Street / South 4th Street. Use this guide to compare Florence, SC and Harrisburg, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Florence
Arrival bus stations in Harrisburg
Florence, S Irby St (Greyhound Bus Stop)
Harrisburg, Market St (Bus Station)
City-centre transport
Getting to Harrisburg, Market St (Bus Station) from Harrisburg city centre
Bus6/13, W · 29m · zł14 · every ~4 min
Harrisburg, Chestnut Street / South 4th Street
City-centre transport
Getting to Harrisburg, Chestnut Street / South 4th Street from Harrisburg city centre
Bus2, 7, 81X, A, B, C, D, M, E · 8m · zł9 · every ~6 min
2, M, 7, D, A, B, 81X, C, 322, E · 9m · zł9 · every ~6 min
Hbg Com Kng B · 15m · zł9
Most popular bus connections from Florence, SC
More options for your journey from Florence, SC to Harrisburg, PA
Here are some other resources that might have the information you need
Most popular buses to and from Harrisburg, PA and Florence, SC
Most popular bus connections to Harrisburg, PA
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