- Must visit
The State Museum of Pennsylvania
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
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The cheapest and fastest buses from Florence, SC to Harrisburg, PA
Showing times, prices and bookable tickets for Nov 03
- Cheapest price on Nov 03
- €119
- Average ticket price on Nov 03
- €119
- Fastest journey on Nov 03
- 21 h 25 m
- Average journey duration on Nov 03
- 21 h 25 m
- Buses on Nov 03
- 1
- Distance
- 722 km
Cheap tickets
The best way to find a cheap bus ticket from Florence, SC to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Harrisburg, PA will cost around €119 if you buy it on the day, but the cheapest tickets can be found for only €119.
Fast buses
It's difficult to get from Florence, SC to Harrisburg, PA without transferring at least 2 times.
4:30 PM 21h25 Florence, SC 1:55 PM Harrisburg, PA €119 1 One-way 2 transfers
4:30 PM 21h25 Florence, SC 1:55 PM Harrisburg, PA €119 1 One-way 2 transfers
Journey information
Overview: Bus from Florence, SC to Harrisburg, PA
USAUSA
Buses from Florence, SC to Harrisburg, PA run on average 1 times per day, taking around 11h 18m. Cheap bus tickets for this journey start at €102 if you book in advance.
The earliest bus runs at 00:05, the last at 23:20. The fastest bus covers the 448 miles (722 km) distance in 10h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Plan this route
Journey facts
- Distance448 miles (722 km)
- Average bus duration11h 18m
- Cheapest ticket price€102
- Buses per day1
- Fastest bus10h 45m
- First bus12:05 AM
- Last bus11:20 PM
- Cheapest MonthJul
- Cheapest DayMon
- High SeasonJul - Sep
- Low SeasonOct - Dec
- Best time to book2 days
Understand & plan this route
Explore this journey
Book with confidence
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Florence, SC to Harrisburg, PA trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Florence, SC to Harrisburg, PA.
Cheap bus tickets from Florence, SC to Harrisburg, PA can start from as little as €102 when you book in advance. The average bus ticket price for Florence, SC to Harrisburg, PA is €159 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Florence, SC to Harrisburg, PA leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Harrisburg, PA leaves at 11:20 PM.
There are 1 buses a day from Florence, SC to Harrisburg, PA which require at least one change with FlixBus, Greyhound. Schedules can vary on holidays or weekends with fewer buses.
Florence, SC to Harrisburg, PA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 04:30PM | Arrival Time 01:55PM | Duration 21h25 | Departure days Tue | Cheapest price €119 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 05:55PM | Duration 21h25 | Departure days Wed, Thu, Fri, Sat | Cheapest price €124 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 06:55PM | Duration 21h25 | Departure days Mon, Wed, Thu, Sun | Cheapest price €99 |
Live departures
Florence, SC to Harrisburg, PA bus times
The table below shows live departures for Florence, SC to Harrisburg, PA buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 9:30 PM Florence, SC | 21h25 | 6:55 PM Harrisburg, PA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Florence, SC to Harrisburg, PA buses with Omio?
FlixBus as well as Greyhound offer buses services from Florence, SC to Harrisburg, PA.
Omio is an official ticket reseller for all your travel options from Florence, SC to Harrisburg, PA.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Florence, SC to Harrisburg, PA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Florence, SC to Harrisburg, PA.
Bus companies
Bus companies from Florence, SC to Harrisburg, PA
Buses from Florence, SC to Harrisburg, PA with FlixBus and Greyhound. Overnight buses available on this route with FlixBus and Greyhound. Use the details below to compare onboard facilities.
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
11h 5m
Cheapest FlixBus Price
€102
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
10h 45m
Cheapest Greyhound Price
€145
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between Florence, SC and Harrisburg, PA
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Florence, SC to Harrisburg, PA, you can count on FlixBus, Greyhound for the best way to get you to Harrisburg, PA. You can also check all possible bus companies who offer a service between Florence, SC and Harrisburg, PA and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Harrisburg, PA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Florence, SC to Harrisburg, PA for bus company FlixBus, Greyhound.
Whether you can cancel your bus ticket from Florence, SC to Harrisburg, PA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from Florence, SC to Harrisburg, PA.
Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Harrisburg, PA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Harrisburg, PA:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Florence, SC to Harrisburg, PA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Florence, SC to Harrisburg, PA with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from Florence, SC to Harrisburg, PA with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from Florence, SC to Harrisburg, PA with the following bus company: FlixBus, Greyhound.
Complete guide to Harrisburg, PA
Things to do in Harrisburg, PA
Discover the best of Harrisburg, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg, PA trip today.
- Must visit
National Civil War Museum
National Civil War museum with broad exhibits on soldiers, civilians, and the war's legacy. It is one of the city's most important history stops.
- Recommended
Fort Hunter Mansion and Park Museum
Museum at Fort Hunter highlighting local river history, mansion life, and the Susquehanna landscape. A quieter favorite with a scenic setting.
- Must visit
Riverfront Park
Riverfront promenade and park system with skyline views, paths, and event spaces. It is one of the most pleasant walks in central Harrisburg.
- Recommended
City Island
Car-free island in the Susquehanna with walking paths, recreation, and broad water views. A classic local escape close to downtown.
- Recommended
Midtown
Victorian neighborhood known for colorful homes, local shops, and a creative atmosphere. It is ideal for strolling and seeing everyday Harrisburg charm.
Pennsylvania Dutch Chicken Pot Pie
Pennsylvania Dutch chicken pot pie is a rich stew with square noodles, chicken, and vegetables. It is a regional comfort food common around Harrisburg.
- Vegetarian
Shoofly Pie
Shoofly pie is a classic Pennsylvania Dutch dessert made with molasses crumb filling. Its deep sweetness makes it a traditional local bakery staple.
- Vegetarian
Whoopie Pie
Whoopie pie features two soft chocolate cake rounds with creamy filling. It is a beloved Amish and Pennsylvania Dutch treat found across the region.
Rubicon
Long-running local favorite serving creative American dishes and seafood in a comfortable, polished neighborhood setting.
Broad Street Market
Historic market with many established local vendors for Pennsylvania Dutch baked goods, pretzels, sandwiches, and regional specialties in a lively setting.
Zeroday Brewing Company
Popular casual tavern and brewery pouring local beer with pub fare. It is well known for a relaxed atmosphere and central location.
US dollar ($)
Moderate for US state capitals; hotels and dining are usually below major East Coast cities, while transit needs and limited cheap tourist areas can raise daily costs.
Average meal costs
- Budget
- $10-15 for fast food or a simple lunch.
- Mid-range
- $18-35 per person for a casual restaurant meal.
- Fine dining
- $50+ per person for upscale dining.
- Coffee
- $3-5 for coffee or a cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
Plan your visit to Harrisburg, PA
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Harrisburg, PA.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Harrisburg, PA, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Common scams include overpriced taxi services and fraudulent ticket sellers near popular attractions. Staying aware of surroundings and using authorized transportation options helps enhance safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Florence, SC to Harrisburg, PA
Find answers to the most common questions about traveling from Florence, SC to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.
Yes, you can take a bus between Florence, SC and Harrisburg, PA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Florence, SC to Harrisburg, PA
Most Florence, SC to Harrisburg, PA buses use the Florence, W Lucas St (TA Gas Station) to Harrisburg, Market St (Bus Station) station pair. Use this guide to compare Florence, SC and Harrisburg, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Florence
Arrival bus stations in Harrisburg
Which Florence, SC station do buses to Harrisburg, PA leave from?
Buses from Florence, SC to Harrisburg, PA leave from Florence, W Lucas St (TA Gas Station). The station is 3 miles (6 km) from Florence, SC city centre at Florence, SC, USA.
Florence, W Lucas St (TA Gas Station)Florence, SC, USA
City-centre transport
Getting to Florence, W Lucas St (TA Gas Station) from Florence city centre
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
TRUE
Florence, W Lucas St (TA Gas Station) bus station facilities and services
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Food and snacks available at the gas station.
Wi-Fi and ATMs
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Tickets and information
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Parking, taxis and toilets
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
Florence, S Irby St (Greyhound Bus Stop)S Irby St, Florence, SC, USA
City-centre transport
Getting to Florence, S Irby St (Greyhound Bus Stop) from Florence city centre
TRUE
Florence, S Irby St (Greyhound Bus Stop) bus station facilities and services
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Tickets and information
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Parking, taxis and toilets
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
Which Harrisburg, PA station do buses from Florence, SC arrive at?
Buses from Florence, SC to Harrisburg, PA arrive at Harrisburg, Market St (Bus Station). Harrisburg, Market St (Bus Station) is 0 miles (1 km) from Harrisburg, PA city centre.
Harrisburg, Market St (Bus Station)Harrisburg, 411 Market St, Harrisburg, PA 17101, USA
City-centre transport
Getting to Harrisburg, Market St (Bus Station) from Harrisburg city centre
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Bus6/13, W · 29m · €3 · every ~4 min
Harrisburg, Market St (Bus Station) bus station facilities and services
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Tickets and information
Ticket office support is available at Harrisburg, Market St (Bus Station).
Parking, taxis and toilets
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Bus stations for Florence, SC to Harrisburg, PA
Check bus stations information for Florence, SC and Harrisburg, PA, including where buses depart and arrive on this route.
When departing from Florence, SC , you have various bus station options to start your journey from including Florence, W Lucas St (TA Gas Station), Florence, S Irby St (Greyhound Bus Stop) . When arriving in Harrisburg, PA , you can end your journey in bus stations like Harrisburg, Market St (Bus Station) .Passengers board the bus most frequently from Florence, W Lucas St (TA Gas Station), which is located around 3 miles (6 km) away from the city centre, and they get off the bus at Harrisburg, Market St (Bus Station), located 1 away from the city centre.
Most popular buses to and from Harrisburg, PA and Florence, SC
Most popular bus connections to Harrisburg, PA
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