- Must visit
The State Museum of Pennsylvania
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
Omio recommends booking the bus as it is the most popular option from Syracuse, NY to Harrisburg, PA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $122 For those with little time, consider booking a flight, which has an average total journey time of 5h 50m. Average ticket prices depend on the travel mode: a bus costs an average of $122, while a flight costs an average of $738.
Distance: 195 miles (315 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$122 Average price Cheapest | $311 Average price | $738 Average price | $52 Average price (fuel + tolls) |
9h 33m Average total duration 9h 3m Onboard + 30m Additional time* | 10h 5m Average total duration 9h 35m Onboard + 30m Additional time* | 5h 50m Average total duration Fastest 3h 50m Onboard + 2h 0m Additional time* | 3h 56m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Syracuse, NY to Harrisburg, PA:
A bus is $194 less than a train for this route with tickets for a train from Syracuse, NY to Harrisburg, PA costing on average $310.
A bus is $622 less than a flight for this route with tickets for a flight from Syracuse, NY to Harrisburg, PA costing on average $738.
Other travel options to Harrisburg, PA take longer:
Bus takes on average 9h 3m.
Train takes on average 9h 36m.
Tickets start at around $116 compared to roughly $52 in fuel and tolls — a saving of about $-64.15. The journey takes 9h 3m versus 3h 56m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:00AM | Arrival Time 05:55PM | Duration 16h55 | Departure days Tue | Cheapest price $114 |
Operator FlixBus | Departure Time 01:15AM | Arrival Time 11:10AM | Duration 9h55 | Departure days Tue, Thu | Cheapest price $74 |
Operator Greyhound | Departure Time 02:00AM | Arrival Time 06:55PM | Duration 16h55 | Departure days Tue, Thu, Sat | Cheapest price $87 |
Operator FlixBus | Departure Time 02:30AM | Arrival Time 02:35PM | Duration 12h05 | Departure days Thu | Cheapest price $122 |
Operator Greyhound | Departure Time 03:55AM | Arrival Time 02:40PM | Duration 10h45 | Departure days Tue, Thu | Cheapest price $76 |
Operator FlixBus | Departure Time 05:15AM | Arrival Time 05:55PM | Duration 12h40 | Departure days Fri | Cheapest price $89 |
Operator Greyhound | Departure Time 07:30AM | Arrival Time 05:20PM | Duration 9h50 | Departure days Thu | Cheapest price $84 |
Operator FlixBus | Departure Time 08:00AM | Arrival Time 07:35PM | Duration 11h35 | Departure days Sat | Cheapest price $66 |
Operator Greyhound | Departure Time 09:25AM | Arrival Time 07:35PM | Duration 10h10 | Departure days Tue, Thu | Cheapest price $76 |
Operator Greyhound | Departure Time 01:25PM | Arrival Time 11:30PM | Duration 10h05 | Departure days Mon | Cheapest price $81 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 02:25AM | Duration 12h25 | Departure days Thu | Cheapest price $98 |
Operator Greyhound | Departure Time 02:25PM | Arrival Time 12:30AM | Duration 10h05 | Departure days Fri | Cheapest price $78 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 06:25AM | Duration 12h25 | Departure days Wed | Cheapest price $125 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 02:25AM | Duration 8h10 | Departure days Tue | Cheapest price $75 |
Operator FlixBus | Departure Time 07:00PM | Arrival Time 06:25AM | Duration 11h25 | Departure days Fri | Cheapest price $120 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 11:10AM | Duration 14h10 | Departure days Tue, Thu | Cheapest price $87 |
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Syracuse, NY to Harrisburg, PA run on average 6 times per day, taking around 9h 3m. Cheap bus tickets for this journey start at $73 if you book in advance.
The earliest bus runs at 00:20, the last at 23:20. The fastest bus covers the 195 miles (315 km) distance in 7h 20m.
Distance 195 miles (315 km) |
Average bus duration 9h 3m |
Cheapest ticket price $73 |
Buses per day 6 |
Fastest bus 7h 20m |
First bus 12:20 AM |
Last bus 11:20 PM |
Cheapest Month Jul |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Oct - Dec |
Discover the best of Harrisburg, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg, PA trip today.
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
National Civil War museum with broad exhibits on soldiers, civilians, and the war's legacy. It is one of the city's most important history stops.
Museum at Fort Hunter highlighting local river history, mansion life, and the Susquehanna landscape. A quieter favorite with a scenic setting.
Riverfront promenade and park system with skyline views, paths, and event spaces. It is one of the most pleasant walks in central Harrisburg.
Car-free island in the Susquehanna with walking paths, recreation, and broad water views. A classic local escape close to downtown.
Victorian neighborhood known for colorful homes, local shops, and a creative atmosphere. It is ideal for strolling and seeing everyday Harrisburg charm.
Pennsylvania Dutch chicken pot pie is a rich stew with square noodles, chicken, and vegetables. It is a regional comfort food common around Harrisburg.
Shoofly pie is a classic Pennsylvania Dutch dessert made with molasses crumb filling. Its deep sweetness makes it a traditional local bakery staple.
Whoopie pie features two soft chocolate cake rounds with creamy filling. It is a beloved Amish and Pennsylvania Dutch treat found across the region.
Long-running local favorite serving creative American dishes and seafood in a comfortable, polished neighborhood setting.
Historic market with many established local vendors for Pennsylvania Dutch baked goods, pretzels, sandwiches, and regional specialties in a lively setting.
Popular casual tavern and brewery pouring local beer with pub fare. It is well known for a relaxed atmosphere and central location.
Moderate for US state capitals; hotels and dining are usually below major East Coast cities, while transit needs and limited cheap tourist areas can raise daily costs.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
Find answers to the most common questions about traveling from Syracuse, NY to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

Most Syracuse, NY to Harrisburg, PA buses use the Syracuse, Walsh Cir (Syracuse Bus Station) to Harrisburg, Market St (Bus Station) station pair. Use this guide to compare Syracuse, NY and Harrisburg, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Syracuse, Walsh Cir (Syracuse Bus Station) is 3 km from Syracuse city centre. Public transport options include:
Syracuse, Walsh Cir (Syracuse Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available throughout the station. ATMs are aTMs are located near the entrance.
Ticket office support is available at Syracuse, Walsh Cir (Syracuse Bus Station).
Available at Syracuse, Walsh Cir (Syracuse Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Syracuse, Walsh Cir (Syracuse Bus Station): The station is wheelchair accessible.
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Ticket office support is available at Harrisburg, Market St (Bus Station).
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Here are some other resources that might have the information you need