- Must visit
The State Museum Of Pennsylvania
The Commonwealth’s flagship history museum with exhibits on archaeology, industry, Civil War history, natural history, and fine art. A strong first stop for understanding Pennsylvania’s story.
Omio recommends booking the bus as it is the most popular option from Syracuse, NY to Harrisburg, PA among Omio's users. If you are prioritising price take the bus with prices starting from $66. For those with little time consider booking a flight which can get you there in 5h 35m. The ticket price range depends on the travel mode: a bus costs an average of $66, and a flight costs an average of $223.
Distance: 195 miles (315 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$111 Average price Cheapest | $195 Average price | $415 Average price | $51 Average price (fuel + tolls) |
10h 1m Average total duration 9h 31m Onboard + 30m Additional time* | 9h 47m Average total duration 9h 17m Onboard + 30m Additional time* | 8h 35m Average total duration Fastest 5h 35m Onboard + 3h 0m Additional time* | 3h 56m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Syracuse, NY to Harrisburg, PA:
A bus is $83 (€68) less than a train for this route with tickets for a train from Syracuse, NY to Harrisburg, PA costing on average $195 (€160).
A bus is $304 (€249) less than a flight for this route with tickets for a flight from Syracuse, NY to Harrisburg, PA costing on average $415 (€340).
Other travel options to Harrisburg, PA take longer:
Train takes on average 9h 17m.
Bus takes on average 9h 31m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:00AM | Arrival Time 05:55PM | Duration 16h55 | Departure days Tue | Cheapest price $114 |
Operator FlixBus | Departure Time 01:15AM | Arrival Time 01:55PM | Duration 12h40 | Departure days Thu, Fri | Cheapest price $109 |
Operator Greyhound | Departure Time 02:00AM | Arrival Time 06:55PM | Duration 16h55 | Departure days Tue, Thu | Cheapest price $87 |
Operator FlixBus | Departure Time 03:15AM | Arrival Time 02:35PM | Duration 11h20 | Departure days Thu, Fri | Cheapest price $126 |
Operator Greyhound | Departure Time 03:55AM | Arrival Time 02:40PM | Duration 10h45 | Departure days Thu, Fri | Cheapest price $111 |
Operator FlixBus | Departure Time 06:15AM | Arrival Time 06:55PM | Duration 12h40 | Departure days Tue | Cheapest price $95 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 06:35PM | Duration 11h20 | Departure days Tue | Cheapest price $185 |
Operator Greyhound | Departure Time 07:30AM | Arrival Time 05:20PM | Duration 9h50 | Departure days Thu, Fri | Cheapest price $109 |
Operator FlixBus | Departure Time 08:00AM | Arrival Time 07:35PM | Duration 11h35 | Departure days Sat | Cheapest price $66 |
Operator Greyhound | Departure Time 09:25AM | Arrival Time 07:35PM | Duration 10h10 | Departure days Thu, Fri | Cheapest price $111 |
Operator Greyhound | Departure Time 01:25PM | Arrival Time 11:30PM | Duration 10h05 | Departure days Mon | Cheapest price $81 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 02:25AM | Duration 12h25 | Departure days Thu | Cheapest price $109 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 06:25AM | Duration 12h25 | Departure days Tue, Wed | Cheapest price $125 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 02:25AM | Duration 8h10 | Departure days Fri | Cheapest price $117 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 11:10AM | Duration 14h10 | Departure days Thu, Fri | Cheapest price $123 |
The table below shows live departures for Syracuse, NY to Harrisburg, PA buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:00 AM Syracuse, NY | 11h35 | 7:35 PM Harrisburg, PA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Syracuse, NY to Harrisburg, PA run on average 5 times per day, taking around 9h 31m. Cheap bus tickets for this journey start at $66 (€54) if you book in advance.
The earliest bus runs at 00:20, the last at 23:20. The fastest bus covers the 195 miles (315 km) distance in 9h 50m.
Distance 195 miles (315 km) |
Average bus duration 9h 31m |
Cheapest ticket price $66 (€54) |
Buses per day 5 |
Fastest bus 9h 50m |
First bus 12:20 AM |
Last bus 11:20 PM |
Cheapest Month Feb |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Harrisburg — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg trip today.
The Commonwealth’s flagship history museum with exhibits on archaeology, industry, Civil War history, natural history, and fine art. A strong first stop for understanding Pennsylvania’s story.
Major museum interpreting the American Civil War from multiple perspectives, with extensive artifacts, documents, and rotating exhibitions. One of Harrisburg’s best-known cultural attractions.
Contemporary art museum featuring regional, national, and international artists in a modern downtown space. A good choice for travelers interested in current exhibitions and local creative culture.
Linear park along the Susquehanna River with walking paths, public art, and excellent skyline views. It is one of Harrisburg’s most pleasant and photogenic places for a stroll.
Recreational island in the Susquehanna offering river views, trails, and open space between downtown and the west shore. Popular for relaxed walks and classic Harrisburg scenery.
The ceremonial and governmental heart of Harrisburg, with landscaped grounds, monuments, and some of the city’s best architecture. A practical and scenic area for sightseeing.
A regional staple made with broad noodles simmered in rich chicken broth, often with chicken and vegetables. It is a classic Central Pennsylvania comfort dish.
A smoky, tangy cured beef sausage from nearby Lebanon County, traditionally sliced for sandwiches or cheese boards. It is one of the area's best-known local meats.
A Pennsylvania Dutch dessert pie with a molasses filling and crumb topping. It is strongly associated with the region's baking traditions.
A well-regarded fine dining spot offering contemporary American cuisine, craft cocktails, and a polished but comfortable atmosphere.
A popular restaurant, brewery, and arts space known for seasonal Pennsylvania ingredients, house beer, and a lively industrial-chic atmosphere.
An established downtown Italian restaurant and wine bar known for brick-oven pizzas, handmade pasta, and an intimate urban setting.
Generally moderate for U.S. travel. Meals and coffee are reasonable, while hotels can rise during events or peak government travel periods.
Tip 18-20% at restaurants for table service, 15-20% for taxis, USD 1-2 per drink at bars, and a few dollars for hotel staff. Tipping is not expected at most fast-food counters.
Find answers to the most common questions about traveling from Syracuse, NY to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

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