- Must visit
The State Museum of Pennsylvania
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
The best way to find a cheap bus ticket from Buffalo, NY to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to Harrisburg, PA will cost around Kč 2,029 if you buy it on the day, but the cheapest tickets can be found for only Kč 1,529.
On Mon, Nov 09, we found 2 buses from Buffalo, NY to Harrisburg, PA, including 2 direct services.
On Mon, Nov 09 the direct buses cover the 335 km distance in an average of 14 h 30 m but if you time it right, some buses will get you there in just 13 h 45 m .
On Mon, Nov 09 the slowest buses will take 15 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Buffalo, NY to Harrisburg, PA run on average 14 times per day, taking around 11h 50m. Cheap bus tickets for this journey start at Kč 1,231 if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:20, the last at 23:55. The fastest bus covers the 208 miles (335 km) distance in 20m.
Distance 208 miles (335 km) |
Average bus duration 11h 50m |
Cheapest ticket price Kč 1,231 |
Buses per day 14 |
Direct buses 1 |
Fastest bus 20m |
First bus 12:20 AM |
Last bus 11:55 PM |
Cheapest Month Jun |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 49 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Buffalo, NY to Harrisburg, PA.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:20AM | Arrival Time 05:55PM | Duration 15h35 | Departure days Wed | Cheapest price Kč 3,310 |
Operator FlixBus | Departure Time 03:20AM | Arrival Time 06:35PM | Duration 15h15 | Departure days Tue | Cheapest price Kč 2,528 |
Operator FlixBus | Departure Time 03:59AM | Arrival Time 06:35PM | Duration 14h36 | Departure days Thu | Cheapest price Kč 2,904 |
Operator Greyhound | Departure Time 04:55AM | Arrival Time 06:40PM | Duration 13h45 | Departure days Mon | Cheapest price Kč 1,529 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 11:35PM | Duration 14h05 | Departure days Thu, Fri | Cheapest price Kč 2,870 |
Operator Greyhound | Departure Time 11:55AM | Arrival Time 01:00AM | Duration 13h05 | Departure days Sat | Cheapest price Kč 3,214 |
Operator FlixBus | Departure Time 02:50PM | Arrival Time 06:25AM | Duration 15h35 | Departure days Sat | Cheapest price Kč 2,603 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 07:25AM | Duration 15h55 | Departure days Thu | Cheapest price Kč 3,205 |
Operator Fullington Trailways | Departure Time 06:00PM | Arrival Time 02:45PM | Duration 20h45 | Departure days Wed | Cheapest price Kč 2,985 |
Operator Fullington Trailways | Departure Time 07:00PM | Arrival Time 03:45PM | Duration 20h45 | Departure days Wed, Fri, Sun | Cheapest price Kč 2,998 |
The table below shows live departures for Buffalo, NY to Harrisburg, PA buses for tomorrow, Monday, November 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:20 AM Buffalo, NY | 15h15 | 6:35 PM Harrisburg, PA | 0 transfersDirect | |
![]() | 4:55 AM Buffalo, NY | 13h45 | 6:40 PM Harrisburg, PA | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Discover the best of Harrisburg, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg, PA trip today.
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
National Civil War museum with broad exhibits on soldiers, civilians, and the war's legacy. It is one of the city's most important history stops.
Museum at Fort Hunter highlighting local river history, mansion life, and the Susquehanna landscape. A quieter favorite with a scenic setting.
Riverfront promenade and park system with skyline views, paths, and event spaces. It is one of the most pleasant walks in central Harrisburg.
Car-free island in the Susquehanna with walking paths, recreation, and broad water views. A classic local escape close to downtown.
Victorian neighborhood known for colorful homes, local shops, and a creative atmosphere. It is ideal for strolling and seeing everyday Harrisburg charm.
Pennsylvania Dutch chicken pot pie is a rich stew with square noodles, chicken, and vegetables. It is a regional comfort food common around Harrisburg.
Shoofly pie is a classic Pennsylvania Dutch dessert made with molasses crumb filling. Its deep sweetness makes it a traditional local bakery staple.
Whoopie pie features two soft chocolate cake rounds with creamy filling. It is a beloved Amish and Pennsylvania Dutch treat found across the region.
Long-running local favorite serving creative American dishes and seafood in a comfortable, polished neighborhood setting.
Historic market with many established local vendors for Pennsylvania Dutch baked goods, pretzels, sandwiches, and regional specialties in a lively setting.
Popular casual tavern and brewery pouring local beer with pub fare. It is well known for a relaxed atmosphere and central location.
Moderate for US state capitals; hotels and dining are usually below major East Coast cities, while transit needs and limited cheap tourist areas can raise daily costs.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Harrisburg, PA.
Find answers to the most common questions about traveling from Buffalo, NY to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

Most Buffalo, NY to Harrisburg, PA buses use the Buffalo, NFTA Metro Center to Harrisburg, Market St (Bus Station) station pair. Use this guide to compare Buffalo, NY and Harrisburg, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Ticket office support is available at Buffalo, NFTA Metro Center.
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
Buffalo has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bar available inside the station.
Free wifi available throughout the station. ATMs are aTM located near the main entrance.
Ticket office support is available at Buffalo.
Available at Buffalo: Parking, Taxis, WC.
Accessibility facilities are available at Buffalo: Station is wheelchair accessible.
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Ticket office support is available at Harrisburg, Market St (Bus Station).
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Check bus stations information for Buffalo, NY and Harrisburg, PA, including where buses depart and arrive on this route.
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