- Must visit
The State Museum Of Pennsylvania
The Commonwealth’s flagship history museum with exhibits on archaeology, industry, Civil War history, natural history, and fine art. A strong first stop for understanding Pennsylvania’s story.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest trains from Florence, SC to Harrisburg, PA
Showing times and prices for Jun 27
Cheapest price
$170
Average price
$170
Fastest journey
15 h 54 m
Average duration
15 h 54 m
Trains per day
1
Distance
722 km
Cheap tickets
The best way to find a cheap train ticket from Florence, SC to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Harrisburg, PA will cost around $170 if you buy it on the day, but the cheapest tickets can be found for only $170.
Fast trains
Of the 1 trains that leave Florence, SC for Harrisburg, PA on Sat, Jun 27, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 27 the direct trains cover the 722 km distance in an average of 15 h 54 m but if you time it right, some trains will get you there in just 15 h 54 m .
On Sat, Jun 27 the slowest trains will take 15 h 54 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
3:32 AM15h54Florence, SC7:26 PMHarrisburg, PA$1701One-way0 transfers
- 3:32 AM15h54Florence, SC7:26 PMHarrisburg, PA$1701One-way0 transfers
Travel Information
Compare bus and train for Florence, SC to Harrisburg, PA
Omio recommends booking the train as it is the most popular option from Florence, SC to Harrisburg, PA among Omio's users. If you are prioritising price take the bus with prices starting from $120. For those with little time consider booking a train which can get you there in 12h 9m. The ticket price range depends on the travel mode: a bus costs an average of $120, and a train costs an average of $170.
Distance: 448 miles (722 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$269 Average price | $187 Average price Cheapest | $103 Average price (fuel + tolls) |
12h 39m Average total duration Fastest 12h 9m Onboard + 30m Additional time* | 21h 55m Average total duration 21h 25m Onboard + 30m Additional time* | 8h 12m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Florence, SC to Harrisburg, PA is a bus with an average price of $187 (€153).
This is compared to other travel options from Florence, SC to Harrisburg, PA:
A bus is $82 (€67) less than a train for this route with tickets for a train from Florence, SC to Harrisburg, PA costing on average $269 (€220).
The fastest way to travel from Florence, SC to Harrisburg, PA is by train with an average journey time of 12h 9m.
Other travel options to Harrisburg, PA take longer:
Bus takes on average 21h 25m.
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Harrisburg, PA including taking a bus and train.
We recommend using the train as it is the most popular way to get from Florence, SC to Harrisburg, PA among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around $269 (€220) compared to roughly $103 (€84) in fuel and tolls — a saving of about $-166.45 (€-136.17). The journey takes 12h 9m versus 8h 12m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Florence, SC to Harrisburg, PA train times
The table below shows live departures for Florence, SC to Harrisburg, PA trains for tomorrow, Sunday, June 21. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 3:32 AM Florence, SC | 15h54 | 7:26 PM Harrisburg, PA | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Harrisburg, PA by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sun
Jun 21
Jun 21
Mon
Jun 22
Jun 22
Tue
Jun 23
Jun 23
Wed
Jun 24
Jun 24
Thu
Jun 25
Jun 25
Fri
Jun 26
Jun 26
Sat
Jun 27
Jun 27
Journey information
Overview: Train from Florence, SC to Harrisburg, PA
USAUSA
Trains from Florence, SC to Harrisburg, PA run on average 2 times per day, taking around 12h 9m. Cheap train tickets for this journey start at $170 (€139) but you can travel from only $120 (€98) by bus.
The earliest train runs at 05:00, the last at 23:32. The fastest train covers the 448 miles (722 km) distance in 14h 13m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $120 (€98)
Distance 448 miles (722 km) |
Average train duration 12h 9m |
Cheapest ticket price $170 (€139) |
Trains per day 2 |
Fastest train 14h 13m |
First train 5:00 AM |
Last train 11:32 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 2 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $120 (€98)
Train companies: Amtrak from Florence, SC to Harrisburg, PA trainsAmtrak trains will get you between Florence, SC and Harrisburg, PA from $120 (€98). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
14h 13m
Cheapest Price
$170 (€139)
Amtrak frequency
2 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone
Complete guide to Harrisburg
Things to do in Harrisburg
Discover the best of Harrisburg — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg trip today.
- Must visit
National Civil War Museum
Major museum interpreting the American Civil War from multiple perspectives, with extensive artifacts, documents, and rotating exhibitions. One of Harrisburg’s best-known cultural attractions.
- Recommended
Susquehanna Art Museum
Contemporary art museum featuring regional, national, and international artists in a modern downtown space. A good choice for travelers interested in current exhibitions and local creative culture.
- Must visit
Riverfront Park
Linear park along the Susquehanna River with walking paths, public art, and excellent skyline views. It is one of Harrisburg’s most pleasant and photogenic places for a stroll.
- Must visit
City Island
Recreational island in the Susquehanna offering river views, trails, and open space between downtown and the west shore. Popular for relaxed walks and classic Harrisburg scenery.
- Must visit
Capitol Complex
The ceremonial and governmental heart of Harrisburg, with landscaped grounds, monuments, and some of the city’s best architecture. A practical and scenic area for sightseeing.
Pennsylvania Dutch Chicken Pot Pie
A regional staple made with broad noodles simmered in rich chicken broth, often with chicken and vegetables. It is a classic Central Pennsylvania comfort dish.
- Gluten-free
Lebanon Bologna
A smoky, tangy cured beef sausage from nearby Lebanon County, traditionally sliced for sandwiches or cheese boards. It is one of the area's best-known local meats.
- Vegetarian
Shoofly Pie
A Pennsylvania Dutch dessert pie with a molasses filling and crumb topping. It is strongly associated with the region's baking traditions.
Rubicon
A well-regarded fine dining spot offering contemporary American cuisine, craft cocktails, and a polished but comfortable atmosphere.
The Millworks
A popular restaurant, brewery, and arts space known for seasonal Pennsylvania ingredients, house beer, and a lively industrial-chic atmosphere.
Bricco
An established downtown Italian restaurant and wine bar known for brick-oven pizzas, handmade pasta, and an intimate urban setting.
United States Dollar
Generally moderate for U.S. travel. Meals and coffee are reasonable, while hotels can rise during events or peak government travel periods.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 20-35 per person at a casual restaurant.
- Fine dining
- USD 50-90 per person at upscale spots.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at restaurants for table service, 15-20% for taxis, USD 1-2 per drink at bars, and a few dollars for hotel staff. Tipping is not expected at most fast-food counters.
FAQs: Trains from Florence, SC to Harrisburg, PA
Find answers to the most common questions about traveling from Florence, SC to Harrisburg, PA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.
Train ticket prices from Florence, SC to Harrisburg, PA can vary. The cheapest ticket starts at $170 (€139), while the average price is around $269 (€220).
The train from Florence, SC to Harrisburg, PA takes 14h 13m and runs 2 per day.
The distance by train from Florence, SC to Harrisburg, PA is 448 miles (722 km).
The first train from Florence, SC to Harrisburg, PA leaves at 5:00 AM.
The last train from Florence, SC to Harrisburg, PA leaves at 11:32 PM.
There is no high speed train available from Florence, SC to Harrisburg, PA.
There is no direct train service currently available from Florence, SC to Harrisburg, PA.
Unfortunately, there is no night train available from Florence, SC to Harrisburg, PA.
The train station in Florence, SC that goes to Harrisburg, PA is Florence Station, Florence, SC, which connects to Harrisburg Station, Harrisburg, PA.
The cheapest way to get from Florence, SC to Harrisburg, PA is by bus, with a cost of around $120 (€98).
The train journey from Florence, SC to Harrisburg, PA offers views of diverse landscapes, including rural countryside, small towns, and sections of the Appalachian Mountains, providing a moderately scenic experience.
A day trip from Florence, SC to Harrisburg, PA is not feasible as the journey duration is 14h 13m. The trip frequency is 2 per day for trains, and the distance is 448 miles (722 km).
In Harrisburg, PA, you can explore City Island for sports and riverboat cruises, visit the Whitaker Center for interactive science exhibits and live performances, and enjoy local foods at the Broad Street Market. Art enthusiasts can visit the Susquehanna Art Museum, while outdoor lovers will appreciate Riverfront Park's scenic views. Key sights include the Pennsylvania State Capitol, the National Civil War Museum, The State Museum of Pennsylvania, Fort Hunter Mansion and Park, and Wildwood Park for nature trails and wildlife observation.
For a fulfilling visit to Harrisburg, PA, 2 to 3 days are ideal to explore key attractions such as the Pennsylvania State Capitol, the National Civil War Museum, and City Island, as well as to enjoy local dining and cultural experiences.
Yes, you can take the train from Florence, SC to Harrisburg, PA.
Since neither Florence, SC nor Harrisburg, PA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
Popular day trips by train from Harrisburg, PA include Lancaster, PA, Ardmore, PA, Exton, PA, Middletown, PA, Downingtown, PA.
We recommend using the train as it is the most popular way to get from Florence, SC to Harrisburg, PA among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Harrisburg, PA, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Common scams include overpriced taxi services and fraudulent ticket sellers near popular attractions. Staying aware of surroundings and using authorized transportation options helps enhance safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Florence, SC to Harrisburg, PA
Most Florence, SC to Harrisburg, PA trains use the Florence Station to Harrisburg Station station pair. Use this guide to compare Florence, SC and Harrisburg, PA train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in Florence
Arrival train stations in Harrisburg
Which Florence, SC station do trains to Harrisburg, PA leave from?
Trains from Florence, SC to Harrisburg, PA leave from Florence Station. The station is 0 miles (1 km) from Florence, SC city centre at 805 East Day Street, Florence, SC 29506, USA.
Florence Station805 East Day Street, Florence, SC 29506, USA+1 800-872-7245
City-centre transport
Getting to Florence Station from Florence city centre
BusGreyhound services available nearby
Florence Station train station facilities and services
Florence Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Information Desk, and Luggage Carts.
Food and drink
Food and drink options are available at Florence Station.
Tickets and information
Ticket office support is available at Florence Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Florence Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at Florence Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence Station: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Aloft Florence, Hyatt Place Florence Downtown, Hotel Florence, Tapestry Collection by Hilton.
Which Harrisburg, PA station do trains from Florence, SC arrive at?
Trains from Florence, SC to Harrisburg, PA arrive at Harrisburg Station. Harrisburg Station is 0 miles (1 km) from Harrisburg, PA city centre.
Harrisburg Station4th and Chestnut Streets, Harrisburg, PA 17101, USA+1 800-872-7245
City-centre transport
Getting to Harrisburg Station from Harrisburg city centre
Harrisburg Station is 1 km from Harrisburg city centre. Public transport options include:
Bus2, 7, 81X, A, B, C, D, M, E, 322 · 6m · $2 · every ~6 min
2, M, 7, D, A, B, 81X, C, 322, E · 7m · $2 · every ~6 min
Hbg Com Kng B · 15m · $2
Harrisburg Station train station facilities and services
Harrisburg Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: The Millworks, Bricco
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Harrisburg Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Harrisburg Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at Harrisburg Station: Parking, Taxis, WC.
Bike and car services
Available at Harrisburg Station: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Harrisburg Station: Elevators, ramps, restrooms.
Shops, hotels and contact
Nearby hotels include Hilton Harrisburg, Crowne Plaza Harrisburg-Hershey, Radisson Hotel Harrisburg.
Most popular train connections from Florence, SC
More options for your journey from Florence, SC to Harrisburg, PA
Here are some other resources that might have the information you need
Most popular trains to and from Harrisburg, PA and Florence, SC
Most popular train connections to Harrisburg, PA
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
