- Must visit
The State Museum of Pennsylvania
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
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The cheapest and fastest trains from Florence, SC to Harrisburg, PA
Showing times, prices and bookable tickets for Sep 20
Cheapest price on Sep 20
€317
Average ticket price on Sep 20
€317
Fastest journey on Sep 20
14 h 13 m
Average journey duration on Sep 20
14 h 13 m
Trains on Sep 20
1
Distance
722 km
Cheap tickets
The best way to find a cheap train ticket from Florence, SC to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Harrisburg, PA will cost around €317 if you buy it on the day, but the cheapest tickets can be found for only €317.
Fast trains
On Sun, Sep 20, we found 1 trains from Florence, SC to Harrisburg, PA, including 1 direct services.
On Sun, Sep 20 the direct trains cover the 722 km distance in an average of 14 h 13 m but if you time it right, some trains will get you there in just 14 h 13 m .
On Sun, Sep 20 the slowest trains will take 14 h 13 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2:32 AM14h13Florence, SC4:45 PMHarrisburg, PA€3171One-way0 transfers
- 2:32 AM14h13Florence, SC4:45 PMHarrisburg, PA€3171One-way0 transfers
Travel Information
Compare bus for Florence, SC to Harrisburg, PA
Omio recommends booking the train as it is the most popular option from Florence, SC to Harrisburg, PA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €165 For those with little time, consider booking a bus, which has an average total journey time of 11h 53m. Average ticket prices depend on the travel mode: a bus costs an average of €165, while a train costs an average of €249.
Distance: 448 miles (722 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
€249 Average price | €165 Average price Cheapest | €85 Average price (fuel + tolls) |
13h 1m Average total duration 12h 31m Onboard + 30m Additional time* | 11h 53m Average total duration Fastest 11h 23m Onboard + 30m Additional time* | 8h 12m Average total duration (door-to-door) |
Most popular train company |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Florence, SC to Harrisburg, PA is a bus with an average price of €165.
This is compared to other travel options from Florence, SC to Harrisburg, PA:
A bus is €84 less than a train for this route with tickets for a train from Florence, SC to Harrisburg, PA costing on average €249.
The fastest way to travel from Florence, SC to Harrisburg, PA is by bus with an average journey time of 11h 23m.
Other travel options to Harrisburg, PA take longer:
Train takes on average 12h 31m.
Yes, you can take a bus between Florence, SC and Harrisburg, PA.
We recommend using the train as it is the most popular way to get from Florence, SC to Harrisburg, PA among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around €249 compared to roughly €85 in fuel and tolls — a saving of about €-163.41. The journey takes 12h 31m versus 8h 12m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Florence, SC to Harrisburg, PA train times
The table below shows live departures for Florence, SC to Harrisburg, PA trains for tomorrow, Saturday, September 19. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 2:32 AM Florence, SC | 14h13 | 4:45 PM Harrisburg, PA | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Harrisburg, PA by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Florence, SC to Harrisburg, PA
USAUSA
Trains from Florence, SC to Harrisburg, PA run on average 2 times per day, taking around 12h 31m. Cheap train tickets for this journey start at €231 but you can travel from only €101 by bus.
The earliest train runs at 05:00, the last at 23:32. The fastest train covers the 448 miles (722 km) distance in 12h 27m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €101
Distance 448 miles (722 km) |
Average train duration 12h 31m |
Cheapest ticket price €231 |
Trains per day 2 |
Fastest train 12h 27m |
First train 5:00 AM |
Last train 11:32 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 2 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €101
Train companies: Amtrak from Florence, SC to Harrisburg, PA trainsAmtrak trains will get you between Florence, SC and Harrisburg, PA from €101. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Amtrak Duration
12h 27m
Cheapest Amtrak Price
€231
Amtrak frequency
2 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone
Complete guide to Harrisburg, PA
Things to do in Harrisburg, PA
Discover the best of Harrisburg, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg, PA trip today.
- Must visit
National Civil War Museum
National Civil War museum with broad exhibits on soldiers, civilians, and the war's legacy. It is one of the city's most important history stops.
- Recommended
Fort Hunter Mansion and Park Museum
Museum at Fort Hunter highlighting local river history, mansion life, and the Susquehanna landscape. A quieter favorite with a scenic setting.
- Must visit
Riverfront Park
Riverfront promenade and park system with skyline views, paths, and event spaces. It is one of the most pleasant walks in central Harrisburg.
- Recommended
City Island
Car-free island in the Susquehanna with walking paths, recreation, and broad water views. A classic local escape close to downtown.
- Recommended
Midtown
Victorian neighborhood known for colorful homes, local shops, and a creative atmosphere. It is ideal for strolling and seeing everyday Harrisburg charm.
Pennsylvania Dutch Chicken Pot Pie
Pennsylvania Dutch chicken pot pie is a rich stew with square noodles, chicken, and vegetables. It is a regional comfort food common around Harrisburg.
- Vegetarian
Shoofly Pie
Shoofly pie is a classic Pennsylvania Dutch dessert made with molasses crumb filling. Its deep sweetness makes it a traditional local bakery staple.
- Vegetarian
Whoopie Pie
Whoopie pie features two soft chocolate cake rounds with creamy filling. It is a beloved Amish and Pennsylvania Dutch treat found across the region.
Rubicon
Long-running local favorite serving creative American dishes and seafood in a comfortable, polished neighborhood setting.
Broad Street Market
Historic market with many established local vendors for Pennsylvania Dutch baked goods, pretzels, sandwiches, and regional specialties in a lively setting.
Zeroday Brewing Company
Popular casual tavern and brewery pouring local beer with pub fare. It is well known for a relaxed atmosphere and central location.
US dollar ($)
Moderate for US state capitals; hotels and dining are usually below major East Coast cities, while transit needs and limited cheap tourist areas can raise daily costs.
Average meal costs
- Budget
- $10-15 for fast food or a simple lunch.
- Mid-range
- $18-35 per person for a casual restaurant meal.
- Fine dining
- $50+ per person for upscale dining.
- Coffee
- $3-5 for coffee or a cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
FAQs: Trains from Florence, SC to Harrisburg, PA
Find answers to the most common questions about traveling from Florence, SC to Harrisburg, PA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.
Train ticket prices from Florence, SC to Harrisburg, PA can vary. The cheapest ticket starts at €231, while the average price is around €249.
The train from Florence, SC to Harrisburg, PA takes 12h 27m and runs 2 per day.
The first train from Florence, SC to Harrisburg, PA leaves at 5:00 AM.
The distance by train from Florence, SC to Harrisburg, PA is 448 miles (722 km).
The last train from Florence, SC to Harrisburg, PA leaves at 11:32 PM.
There is no high speed train available from Florence, SC to Harrisburg, PA.
There is no direct train service currently available from Florence, SC to Harrisburg, PA.
Unfortunately, there is no night train available from Florence, SC to Harrisburg, PA.
The train station in Florence, SC that goes to Harrisburg, PA is Florence Station, Florence, SC, which connects to Harrisburg Station, Harrisburg, PA.
The cheapest way to get from Florence, SC to Harrisburg, PA is by bus, with a cost of around €101.
The train journey from Florence, SC to Harrisburg, PA offers views of diverse landscapes, including rural countryside, small towns, and sections of the Appalachian Mountains, providing a moderately scenic experience.
A day trip from Florence, SC to Harrisburg, PA is not feasible as the journey duration is 12h 27m. The trip frequency is 2 per day for trains, and the distance is 448 miles (722 km).
In Harrisburg, PA, you can explore City Island for sports and riverboat cruises, visit the Whitaker Center for interactive science exhibits and live performances, and enjoy local foods at the Broad Street Market. Art enthusiasts can visit the Susquehanna Art Museum, while outdoor lovers will appreciate Riverfront Park's scenic views. Key sights include the Pennsylvania State Capitol, the National Civil War Museum, The State Museum of Pennsylvania, Fort Hunter Mansion and Park, and Wildwood Park for nature trails and wildlife observation.
For a fulfilling visit to Harrisburg, PA, 2 to 3 days are ideal to explore key attractions such as the Pennsylvania State Capitol, the National Civil War Museum, and City Island, as well as to enjoy local dining and cultural experiences.
Yes, you can take the train from Florence, SC to Harrisburg, PA.
Since neither Florence, SC nor Harrisburg, PA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
Popular day trips by train from Harrisburg, PA include Lancaster, PA, Ardmore, PA, Exton, PA, Middletown, PA, Downingtown, PA.
We recommend using the train as it is the most popular way to get from Florence, SC to Harrisburg, PA among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Harrisburg, PA, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Common scams include overpriced taxi services and fraudulent ticket sellers near popular attractions. Staying aware of surroundings and using authorized transportation options helps enhance safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Florence, SC to Harrisburg, PA
Most Florence, SC to Harrisburg, PA trains use the Florence Station to Harrisburg Station station pair. Use this guide to compare Florence, SC and Harrisburg, PA train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in Florence
Arrival train stations in Harrisburg
Which Florence, SC station do trains to Harrisburg, PA leave from?
Trains from Florence, SC to Harrisburg, PA leave from Florence Station. The station is 0 miles (1 km) from Florence, SC city centre at 805 East Day Street, Florence, SC 29506, USA.
Florence Station805 East Day Street, Florence, SC 29506, USA+1 800-872-7245
City-centre transport
Getting to Florence Station from Florence city centre
BusGreyhound services available nearby
Florence Station train station facilities and services
Florence Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Information Desk, and Luggage Carts.
Food and drink
Food and drink options are available at Florence Station.
Tickets and information
Ticket office support is available at Florence Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Florence Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at Florence Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence Station: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Aloft Florence, Hyatt Place Florence Downtown, Hotel Florence, Tapestry Collection by Hilton.
Which Harrisburg, PA station do trains from Florence, SC arrive at?
Trains from Florence, SC to Harrisburg, PA arrive at Harrisburg Station. Harrisburg Station is 0 miles (1 km) from Harrisburg, PA city centre.
Harrisburg Station4th and Chestnut Streets, Harrisburg, PA 17101, USA+1 800-872-7245
City-centre transport
Getting to Harrisburg Station from Harrisburg city centre
Harrisburg Station is 1 km from Harrisburg city centre. Public transport options include:
Bus2, 7, 81X, A, B, C, D, M, E, 322 · 6m · €2 · every ~6 min
2, M, 7, D, A, B, 81X, C, 322, E · 7m · €2 · every ~6 min
Hbg Com Kng B · 15m · €2
Harrisburg Station train station facilities and services
Harrisburg Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: The Millworks, Bricco
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Harrisburg Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Harrisburg Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at Harrisburg Station: Parking, Taxis, WC.
Bike and car services
Available at Harrisburg Station: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Harrisburg Station: Elevators, ramps, restrooms.
Shops, hotels and contact
Nearby hotels include Hilton Harrisburg, Crowne Plaza Harrisburg-Hershey, Radisson Hotel Harrisburg.
Most popular train connections from Florence, SC
More options for your journey from Florence, SC to Harrisburg, PA
Here are some other resources that might have the information you need
Most popular trains to and from Harrisburg, PA and Florence, SC
Most popular train connections to Harrisburg, PA
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