- Must visit
The State Museum of Pennsylvania
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
Cheapest price
$170
Average price
$246
Fastest journey
14 h 17 m
Average duration
15 h 6 m
Trains per day
2
Distance
722 km
The best way to find a cheap train ticket from Florence, SC to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Harrisburg, PA will cost around $246 if you buy it on the day, but the cheapest tickets can be found for only $170.
Of the 2 trains that leave Florence, SC for Harrisburg, PA on Thu, Aug 06, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 06 the direct trains cover the 722 km distance in an average of 15 h 6 m but if you time it right, some trains will get you there in just 14 h 17 m .
On Thu, Aug 06 the slowest trains will take 15 h 54 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Trains from Florence, SC to Harrisburg, PA run on average 2 times per day, taking around 12h 9m. Cheap train tickets for this journey start at $170 but you can travel from only $121 by bus.
The earliest train runs at 05:00, the last at 23:32. The fastest train covers the 448 miles (722 km) distance in 14h 13m.
Distance 448 miles (722 km) |
Average train duration 12h 9m |
Cheapest ticket price $170 |
Trains per day 2 |
Fastest train 14h 13m |
First train 5:00 AM |
Last train 11:32 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 2 days |
The table below shows live departures for Florence, SC to Harrisburg, PA trains for tomorrow, Wednesday, August 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:32 AM Florence, SC | 14h17 | 4:49 PM Harrisburg, PA | 0 transfersDirect | |
![]() | 3:32 AM Florence, SC | 15h54 | 7:26 PM Harrisburg, PA | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Discover the best of Harrisburg, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg, PA trip today.
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
National Civil War museum with broad exhibits on soldiers, civilians, and the war's legacy. It is one of the city's most important history stops.
Museum at Fort Hunter highlighting local river history, mansion life, and the Susquehanna landscape. A quieter favorite with a scenic setting.
Riverfront promenade and park system with skyline views, paths, and event spaces. It is one of the most pleasant walks in central Harrisburg.
Car-free island in the Susquehanna with walking paths, recreation, and broad water views. A classic local escape close to downtown.
Victorian neighborhood known for colorful homes, local shops, and a creative atmosphere. It is ideal for strolling and seeing everyday Harrisburg charm.
Pennsylvania Dutch chicken pot pie is a rich stew with square noodles, chicken, and vegetables. It is a regional comfort food common around Harrisburg.
Shoofly pie is a classic Pennsylvania Dutch dessert made with molasses crumb filling. Its deep sweetness makes it a traditional local bakery staple.
Whoopie pie features two soft chocolate cake rounds with creamy filling. It is a beloved Amish and Pennsylvania Dutch treat found across the region.
Long-running local favorite serving creative American dishes and seafood in a comfortable, polished neighborhood setting.
Historic market with many established local vendors for Pennsylvania Dutch baked goods, pretzels, sandwiches, and regional specialties in a lively setting.
Popular casual tavern and brewery pouring local beer with pub fare. It is well known for a relaxed atmosphere and central location.
Moderate for US state capitals; hotels and dining are usually below major East Coast cities, while transit needs and limited cheap tourist areas can raise daily costs.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
Find answers to the most common questions about traveling from Florence, SC to Harrisburg, PA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

Most Florence, SC to Harrisburg, PA trains use the Florence Station to Harrisburg Station station pair. Use this guide to compare Florence, SC and Harrisburg, PA train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Florence Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Information Desk, and Luggage Carts.
Food and drink options are available at Florence Station.
Ticket office support is available at Florence Station. Information desks are located in the main hall.
Luggage storage is available at Florence Station. Lost and found is available at the station.
Available at Florence Station: Parking, Taxis, WC.
Accessibility facilities are available at Florence Station: Elevators, ramps.
Nearby hotels include Aloft Florence, Hyatt Place Florence Downtown, Hotel Florence, Tapestry Collection by Hilton.
Harrisburg Station is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: The Millworks, Bricco
Free. ATMs are available in the train station.
Ticket office support is available at Harrisburg Station. Information desks are located in the main hall.
Luggage storage is available at Harrisburg Station. Lost and found is available at the station.
Available at Harrisburg Station: Parking, Taxis, WC.
Available at Harrisburg Station: Bike Parking, Car Rental.
Accessibility facilities are available at Harrisburg Station: Elevators, ramps, restrooms.
Nearby hotels include Hilton Harrisburg, Crowne Plaza Harrisburg-Hershey, Radisson Hotel Harrisburg.
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