- Must visit
Nasher Museum of Art
Major art museum at Duke with global collections, rotating exhibitions, and strong programs in modern and classical art.
Cheapest price on Sep 09
$142
Average ticket price on Sep 09
$146
Fastest journey on Sep 09
15 h 55 m
Average journey duration on Sep 09
21 h 58 m
Buses on Sep 09
5
Distance
658 km
The best way to find a cheap bus ticket from Cleveland, OH to Durham, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Cleveland, OH to Durham, NC will cost around $146 if you buy it on the day, but the cheapest tickets can be found for only $142.
It's difficult to get from Cleveland, OH to Durham, NC without transferring at least once.










Omio recommends booking the bus as it is the most popular option from Cleveland, OH to Durham, NC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $146 For those with little time, consider booking a bus, which has an average total journey time of 21h 52m. Average ticket prices depend on the travel mode: a bus costs an average of $146, while a train costs an average of $243.
Distance: 408 miles (658 km)
Most popular Bus | Train | Driving |
|---|---|---|
$146 Average price Cheapest | $243 Average price | $110 Average price (fuel + tolls) |
21h 52m Average total duration Fastest 21h 22m Onboard + 30m Additional time* | 29h 36m Average total duration 29h 6m Onboard + 30m Additional time* | 8h 19m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Cleveland, OH to Durham, NC:
A bus is $97 (€78) less than a train for this route with tickets for a train from Cleveland, OH to Durham, NC costing on average $243 (€196).
Other travel options to Durham, NC take longer:
Bus takes on average 21h 22m.
Train takes on average 29h 6m.
Tickets start at around $146 (€118) compared to roughly $110 (€89) in fuel and tolls — a saving of about $-35.52 (€-28.69). The journey takes 21h 22m versus 8h 19m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 02:40AM | Arrival Time 10:00PM | Duration 19h20 | Departure days Mon, Wed, Sun | Cheapest price $146 |
Operator Greyhound | Departure Time 07:40AM | Arrival Time 03:00AM | Duration 19h20 | Departure days Sat | Cheapest price $166 |
Operator Greyhound | Departure Time 03:50PM | Arrival Time 02:10PM | Duration 22h20 | Departure days Fri | Cheapest price $99 |
Operator Greyhound USA | Departure Time 04:30PM | Arrival Time 08:25AM | Duration 15h55 | Departure days Tue, Wed, Sun | Cheapest price $146 |
Operator Barons Bus | Departure Time 05:40PM | Arrival Time 09:00AM | Duration 39h20 | Departure days Tue, Wed | Cheapest price $142 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 10:00PM | Duration 25h40 | Departure days Fri | Cheapest price $102 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 06:10PM | Duration 21h40 | Departure days Thu | Cheapest price $160 |
The table below shows live departures for Cleveland, OH to Durham, NC buses for today, Tuesday, September 8. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:30 PM Cleveland, OH | 15h55 | 8:25 AM Durham, NC | 2 transfers | |
![]() | 4:30 PM Cleveland, OH | 15h55 | 8:25 AM Durham, NC | 1 transfer | |
![]() | 5:40 PM Cleveland, OH | 39h20 | 9:00 AM Durham, NC | 2 transfers | |
| Wednesday, September 9 | |||||
![]() | 2:40 AM Cleveland, OH | 19h20 | 10:00 PM Durham, NC | 2 transfers | |
![]() | 2:40 AM Cleveland, OH | 19h20 | 10:00 PM Durham, NC | 1 transfer | |
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Cleveland, OH to Durham, NC run on average 3 times per day, taking around 21h 22m. Cheap bus tickets for this journey start at $142 (€115) if you book in advance.
The earliest bus runs at 01:20, the last at 22:10. The fastest bus covers the 408 miles (658 km) distance in 15h 55m.
Distance 408 miles (658 km) |
Average bus duration 21h 22m |
Cheapest ticket price $142 (€115) |
Buses per day 3 |
Fastest bus 15h 55m |
First bus 1:20 AM |
Last bus 10:10 PM |
Cheapest Month Oct |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Durham, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Durham, NC trip today.
Major art museum at Duke with global collections, rotating exhibitions, and strong programs in modern and classical art.
Hands-on science museum with aerospace, physics, wildlife, and family exhibits in downtown Durham.
Historic site and museum exploring Washington Duke, tobacco farming, and Durham's industrial origins.
Beloved public garden with terraces, woodland paths, and seasonal blooms, ideal for a scenic walk near Duke.
Lively downtown district for walking among warehouses, public art, music venues, and restored tobacco-era spaces.
Scenic riverside greenway for walking and cycling, connecting downtown with quiet stretches of restored nature.
Eastern North Carolina chopped pork barbecue with a tangy vinegar-pepper sauce. A defining regional staple widely loved across Durham and the Triangle.
Slow-cooked pork shoulder or whole hog, often served on a plate with slaw and hush puppies. It reflects the area’s deep barbecue tradition.
Fried cornmeal batter balls served with barbecue or seafood. They are a classic Southern side found on many Durham menus.
Refined restaurant showcasing seasonal North Carolina ingredients with polished service. Known for elevated Southern cooking and a stylish setting.
Beloved local bakery and café serving excellent pastries, breads, and coffee. A dependable stop for breakfast, lunch, or a quick snack.
Popular casual spot for inventive biscuit sandwiches, shrimp and grits, and Southern brunch favorites in a lively downtown atmosphere.
Moderate for a US college city; hotels and dining are mid-priced, transit is limited, but many casual meals and coffee shops are affordable.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
Find answers to the most common questions about traveling from Cleveland, OH to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.

Most Cleveland, OH to Durham, NC buses use the Cleveland, Chester Ave At the Greyhound Station (South Side) to Durham, W Pettigrew St (Greyhound Bus Station) station pair. Use this guide to compare Cleveland, OH and Durham, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Cleveland, Chester Ave At the Greyhound Station (South Side) is 1 km from Cleveland city centre. Public transport options include:
Cleveland, Chester Ave At the Greyhound Station (South Side) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bar available onsite.
Free WiFi available for passengers. ATMs are available at Cleveland, Chester Ave At the Greyhound Station (South Side).
Ticket office support is available at Cleveland, Chester Ave At the Greyhound Station (South Side).
Available at Cleveland, Chester Ave At the Greyhound Station (South Side): Parking, Taxis, WC.
Accessibility facilities are available at Cleveland, Chester Ave At the Greyhound Station (South Side): Station is wheelchair accessible.
Here are some other resources that might have the information you need