The cheapest and fastest buses from Philadelphia, PA to Durham, NC
Cheapest price
$103
Average price
$121
Fastest journey
9 h 20 m
Average duration
10 h 58 m
Buses per day
15
Distance
548 km
The best way to find a cheap bus ticket from Philadelphia, PA to Durham, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Philadelphia, PA to Durham, NC will cost around $121 if you buy it on the day, but the cheapest tickets can be found for only $103.
Of the 15 buses that leave Philadelphia, PA for Durham, NC on Thu, Apr 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Apr 23 the direct buses cover the 548 km distance in an average of 10 h 58 m but if you time it right, some buses will get you there in just 9 h 20 m .
On Thu, Apr 23 the slowest buses will take 12 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
5:50 PM11h00Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA4:50 AMDurham Station$1031One-way0 transfers
FlixBus+
11:45 AM13h20Philadelphia, Schuylkill Ave (Cira Centre South), PA1:05 AMDurham Station$1161One-way1 transfer
FlixBus · FlixBus6:45 PM13h40Philadelphia, Schuylkill Ave (Cira Centre South), PA8:25 AMDurham Station$1171One-way1 transfer
+
FlixBus8:30 PM11h55Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA8:25 AMDurham Station$1171One-way1 transfer
undefined · undefined12:45 PM12h20Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA1:05 AMDurham Station$1181One-way1 transfer
FlixBus · FlixBus6:30 PM9h20Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA3:50 AMDurham Station$1241One-way1 transfer
FlixBus+
2:30 PM10h35Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA1:05 AMDurham Station$1201One-way1 transfer
5:50 PM11h00Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA4:50 AMDurham Station$1031One-way0 transfers
+
FlixBus8:30 PM11h55Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA8:25 AMDurham Station$1171One-way1 transfer
FlixBus · FlixBus10:00 AM12h00Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA10:00 PMDurham Station$1241One-way1 transfer
Travel Information
Compare train, bus, and flight for Philadelphia, PA to Durham, NC
Omio recommends booking the train as it is the most popular option from Philadelphia, PA to Durham, NC among Omio's users. If you are prioritising price take the bus with prices starting from $64. For those with little time consider booking a flight which can get you there in 5h 32m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $64, and a flight costs an average of $181.
Distance: 340 miles (548 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$94 Average price Cheapest | $168 Average price | $298 Average price |
10h 15m Average total duration 9h 45m Onboard + 30m Additional time* | 10h 1m Average total duration 9h 31m Onboard + 30m Additional time* | 8h 32m Average total duration Fastest 5h 32m Onboard + 3h 0m Additional time* |
0.5 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.6 - 3.3kg CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Philadelphia, PA to Durham, NC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:50AM | Arrival Time 02:10PM | Duration 12h20 | Departure days Thu | Cheapest price $123 |
Operator Greyhound | Departure Time 02:00AM | Arrival Time 02:10PM | Duration 12h10 | Departure days Thu | Cheapest price $123 |
Operator FlixBus | Departure Time 06:00AM | Arrival Time 10:00PM | Duration 16h00 | Departure days Thu | Cheapest price $121 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 10:00PM | Duration 12h15 | Departure days Thu | Cheapest price $121 |
Operator FlixBus | Departure Time 10:00AM | Arrival Time 10:00PM | Duration 12h00 | Departure days Thu | Cheapest price $124 |
Operator Greyhound | Departure Time 11:45AM | Arrival Time 01:05AM | Duration 13h20 | Departure days Thu | Cheapest price $116 |
Operator Greyhound | Departure Time 12:45PM | Arrival Time 01:05AM | Duration 12h20 | Departure days Thu | Cheapest price $118 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 03:50AM | Duration 13h35 | Departure days Thu | Cheapest price $138 |
Operator Greyhound | Departure Time 02:30PM | Arrival Time 01:05AM | Duration 10h35 | Departure days Thu | Cheapest price $120 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 03:50AM | Duration 12h20 | Departure days Thu | Cheapest price $124 |
Operator Greyhound | Departure Time 05:50PM | Arrival Time 04:50AM | Duration 11h00 | Departure days Thu | Cheapest price $103 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 03:50AM | Duration 9h20 | Departure days Thu | Cheapest price $124 |
Operator FlixBus | Departure Time 06:45PM | Arrival Time 08:25AM | Duration 13h40 | Departure days Thu | Cheapest price $117 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 08:25AM | Duration 11h55 | Departure days Thu | Cheapest price $117 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 02:10PM | Duration 15h40 | Departure days Thu | Cheapest price $121 |
Live departures
Philadelphia, PA to Durham, NC bus times
The table below shows live departures for Philadelphia, PA to Durham, NC buses for today, Wednesday, April 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:50 PM Philadelphia, PA | 11h00 | 4:50 AM Durham, NC | 0 transfersDirect | |
![]() | 6:30 PM Philadelphia, PA | 9h20 | 3:50 AM Durham, NC | 1 transfer | |
| Thursday, April 23 | |||||
FlixBus+ undefined · undefined | 1:50 AM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 12h20 | 2:10 PM Durham Station | 2 transfers | |
undefined · undefined · undefined | 2:00 AM Philadelphia, Schuylkill Ave (Cira Centre South), PA | 12h10 | 2:10 PM Durham Station | 2 transfers | |
+ FlixBus | 6:00 AM Philadelphia, Schuylkill Ave (Cira Centre South), PA | 16h00 | 10:00 PM Durham Station | 1 transfer | |
undefined · undefined+ FlixBus | 9:45 AM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 12h15 | 10:00 PM Durham Station | 2 transfers | |
FlixBus · FlixBus | 10:00 AM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 12h00 | 10:00 PM Durham Station | 1 transfer | |
FlixBus+![]() | 11:45 AM Philadelphia, Schuylkill Ave (Cira Centre South), PA | 13h20 | 1:05 AM Durham Station | 1 transfer | |
undefined · undefined | 12:45 PM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 12h20 | 1:05 AM Durham Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Philadelphia, PA to Durham, NC by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Apr 26
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Apr 28
Apr 29
Why should you book Philadelphia, PA to Durham, NC buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Philadelphia, PA to Durham, NC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Philadelphia, PA to Durham, NC.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Philadelphia, PA to Durham, NC.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Philadelphia, PA to Durham, NC.
Journey information
Overview: Bus from Philadelphia, PA to Durham, NC
Buses from Philadelphia, PA to Durham, NC run on average 17 times per day, taking around 9h 45m. Cheap bus tickets for this journey start at $64 (€51) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:50, the last at 23:30. The fastest bus covers the 340 miles (548 km) distance in 10h 35m.
Distance 340 miles (548 km) |
Average bus duration 9h 45m |
Cheapest ticket price $64 (€51) |
Buses per day 17 |
Direct buses 1 |
Fastest bus 10h 35m |
First bus 12:50 AM |
Last bus 11:30 PM |
Cheapest Month Aug |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 28 days |
Bus providers: FlixBus, Greyhound from Philadelphia, PA to Durham, NCYou can travel by bus between Philadelphia, PA to Durham, NC with FlixBus, Greyhound for as low as $64 (€51). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Philadelphia, PA to Durham, NC
Find answers to the most common questions about traveling from Philadelphia, PA to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Philadelphia, PA to Durham, NC
Most popular bus connections from Philadelphia, PA
More options for your journey from Philadelphia, PA to Durham, NC
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