- Must visit
Nasher Museum of Art
Major art museum at Duke with global collections, rotating exhibitions, and strong programs in modern and classical art.
Cheapest price on Oct 24
Kč 1,531
Average ticket price on Oct 24
Kč 1,793
Fastest journey on Oct 24
11 h
Average journey duration on Oct 24
11 h
Buses on Oct 24
2
Distance
548 km
The best way to find a cheap bus ticket from Philadelphia, PA to Durham, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Philadelphia, PA to Durham, NC will cost around Kč 1,793 if you buy it on the day, but the cheapest tickets can be found for only Kč 1,531.
On Sat, Oct 24, we found 2 buses from Philadelphia, PA to Durham, NC, including 2 direct services.
On Sat, Oct 24 the direct buses cover the 548 km distance in an average of 11 h but if you time it right, some buses will get you there in just 11 h .
On Sat, Oct 24 the slowest buses will take 11 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Buses from Philadelphia, PA to Durham, NC run on average 12 times per day, taking around 10h 3m. Cheap bus tickets for this journey start at Kč 1,331 but you can travel from only Kč 816 by flight.
There are 1 buses per day. The earliest bus runs at 00:50, the last at 23:20. The fastest bus covers the 340 miles (548 km) distance in 7h 50m.
Distance 340 miles (548 km) |
Average bus duration 10h 3m |
Cheapest ticket price Kč 1,331 |
Buses per day 12 |
Direct buses 1 |
Fastest bus 7h 50m |
First bus 12:50 AM |
Last bus 11:20 PM |
Cheapest Month Oct |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 21 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Philadelphia, PA to Durham, NC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:05AM | Arrival Time 02:10PM | Duration 11h05 | Departure days Thu, Fri, Sun | Cheapest price Kč 1,475 |
Operator FlixBus | Departure Time 05:00AM | Arrival Time 02:45PM | Duration 9h45 | Departure days Fri | Cheapest price Kč 1,661 |
Operator FlixBus | Departure Time 11:55AM | Arrival Time 10:00PM | Duration 10h05 | Departure days Thu, Fri, Sun | Cheapest price Kč 1,672 |
Operator FlixBus | Departure Time 01:45PM | Arrival Time 02:00AM | Duration 12h15 | Departure days Tue | Cheapest price Kč 1,493 |
Operator Greyhound | Departure Time 02:30PM | Arrival Time 01:30AM | Duration 11h00 | Departure days Thu, Fri, Sun | Cheapest price Kč 1,709 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 02:40AM | Duration 9h25 | Departure days Fri, Sun | Cheapest price Kč 1,661 |
Operator Greyhound | Departure Time 05:50PM | Arrival Time 04:50AM | Duration 11h00 | Departure days Thu, Fri, Sun | Cheapest price Kč 1,599 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 03:50AM | Duration 9h20 | Departure days Thu, Fri, Sun | Cheapest price Kč 1,475 |
Operator FlixBus | Departure Time 07:20PM | Arrival Time 08:25AM | Duration 13h05 | Departure days Thu | Cheapest price Kč 1,795 |
Operator Greyhound | Departure Time 09:50PM | Arrival Time 08:50AM | Duration 11h00 | Departure days Mon, Tue, Wed, Sat | Cheapest price Kč 1,531 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 08:25AM | Duration 10h25 | Departure days Fri, Sun | Cheapest price Kč 1,649 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 02:10PM | Duration 15h40 | Departure days Thu, Fri, Sun | Cheapest price Kč 1,549 |
Operator Greyhound | Departure Time 10:50PM | Arrival Time 09:50AM | Duration 11h00 | Departure days Mon, Sat | Cheapest price Kč 2,055 |
The table below shows live departures for Philadelphia, PA to Durham, NC buses for today, Friday, October 23. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ + FlixBus | 11:55 AM Philadelphia Bus Station | 10h05 | 10:00 PM Durham Station | 2 transfers | |
FlixBus+![]() | 2:30 PM Philadelphia Bus Station | 11h00 | 1:30 AM Durham Station | 1 transfer | |
FlixBus · FlixBus | 5:15 PM Philadelphia Bus Station | 9h25 | 2:40 AM Durham Station | 1 transfer | |
![]() | 5:50 PM Philadelphia Bus Station | 11h00 | 4:50 AM Durham Station | 0 transfersDirect | |
FlixBus · FlixBus | 6:30 PM Philadelphia Bus Station | 9h20 | 3:50 AM Durham Station | 1 transfer | |
FlixBus · FlixBus | 10:00 PM Philadelphia Bus Station | 10h25 | 8:25 AM Durham Station | 1 transfer | |
FlixBus+ · | 10:30 PM Philadelphia Bus Station | 15h40 | 2:10 PM Durham Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Durham, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Durham, NC trip today.
Major art museum at Duke with global collections, rotating exhibitions, and strong programs in modern and classical art.
Hands-on science museum with aerospace, physics, wildlife, and family exhibits in downtown Durham.
Historic site and museum exploring Washington Duke, tobacco farming, and Durham's industrial origins.
Beloved public garden with terraces, woodland paths, and seasonal blooms, ideal for a scenic walk near Duke.
Lively downtown district for walking among warehouses, public art, music venues, and restored tobacco-era spaces.
Scenic riverside greenway for walking and cycling, connecting downtown with quiet stretches of restored nature.
Eastern North Carolina chopped pork barbecue with a tangy vinegar-pepper sauce. A defining regional staple widely loved across Durham and the Triangle.
Slow-cooked pork shoulder or whole hog, often served on a plate with slaw and hush puppies. It reflects the area’s deep barbecue tradition.
Fried cornmeal batter balls served with barbecue or seafood. They are a classic Southern side found on many Durham menus.
Refined restaurant showcasing seasonal North Carolina ingredients with polished service. Known for elevated Southern cooking and a stylish setting.
Beloved local bakery and café serving excellent pastries, breads, and coffee. A dependable stop for breakfast, lunch, or a quick snack.
Popular casual spot for inventive biscuit sandwiches, shrimp and grits, and Southern brunch favorites in a lively downtown atmosphere.
Moderate for a US college city; hotels and dining are mid-priced, transit is limited, but many casual meals and coffee shops are affordable.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Durham, NC.
Find answers to the most common questions about traveling from Philadelphia, PA to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.

Most Philadelphia, PA to Durham, NC buses use the Philadelphia, Greyhound Bus Station to Durham, W Pettigrew St (Greyhound Bus Station) station pair. Use this guide to compare Philadelphia, PA and Durham, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Philadelphia, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bars and vending machines are available.
Free Wi-Fi available in the waiting area. ATMs are an ATM is available near the entrance.
Ticket office support is available at Philadelphia, Greyhound Bus Station.
Available at Philadelphia, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Greyhound Bus Station: The station is wheelchair accessible with ramps and elevators.
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) is 2 km from Philadelphia city centre. Public transport options include:
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park). ATMs are available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park).
Ticket office support is available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park).
Available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park): Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park): The bus stop is accessible with ramps.
Philadelphia, Schuylkill Ave (Cira Centre South) is 1 km from Philadelphia city centre. Public transport options include:
Philadelphia, Schuylkill Ave (Cira Centre South) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available in the waiting area. ATMs are available at Philadelphia, Schuylkill Ave (Cira Centre South).
Ticket office support is available at Philadelphia, Schuylkill Ave (Cira Centre South).
Available at Philadelphia, Schuylkill Ave (Cira Centre South): Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Schuylkill Ave (Cira Centre South): Wheelchair accessible area.
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