- Must visit
Nasher Museum of Art
Major art museum at Duke with global collections, rotating exhibitions, and strong programs in modern and classical art.
Cheapest price
$63
Average price
$70
Fastest journey
9 h 20 m
Average duration
9 h 52 m
Buses per day
9
Distance
548 km
The best way to find a cheap bus ticket from Philadelphia, PA to Durham, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Philadelphia, PA to Durham, NC will cost around $70 if you buy it on the day, but the cheapest tickets can be found for only $63.
Of the 9 buses that leave Philadelphia, PA for Durham, NC on Sun, Jul 26, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jul 26 the direct buses cover the 548 km distance in an average of 9 h 52 m but if you time it right, some buses will get you there in just 9 h 20 m .
On Sun, Jul 26 the slowest buses will take 10 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus+
Omio recommends booking the train as it is the most popular option from Philadelphia, PA to Durham, NC among Omio's users. If you are prioritising price take the bus with prices starting from $53. For those with little time consider booking a flight which can get you there in 4h 32m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $53, and a flight costs an average of $159.
Distance: 340 miles (548 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$75 Average price Cheapest | $146 Average price | $328 Average price | $70 Average price (fuel + tolls) |
10h 15m Average total duration 9h 45m Onboard + 30m Additional time* | 10h 1m Average total duration 9h 31m Onboard + 30m Additional time* | 7h 32m Average total duration Fastest 4h 32m Onboard + 3h 0m Additional time* | 7h 58m Average total duration (door-to-door) |
0.5 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.6 - 3.3kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Philadelphia, PA to Durham, NC:
A bus is $71 (€71) less than a train for this route with tickets for a train from Philadelphia, PA to Durham, NC costing on average $146 (€146).
A bus is $253 (€253) less than a flight for this route with tickets for a flight from Philadelphia, PA to Durham, NC costing on average $328 (€328).
Other travel options to Durham, NC take longer:
Train takes on average 9h 31m.
Bus takes on average 9h 45m.
You'll arrive about -2h -47m sooner (9h 45m by bus vs 7h 58m by car) and save roughly $-5.24 (€-5.24) compared to fuel and tolls ($75 (€75) vs $70 (€70)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Greyhound.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:10AM | Arrival Time 02:10PM | Duration 11h00 | Departure days Sun | Cheapest price $71 |
Operator FlixBus | Departure Time 05:00AM | Arrival Time 02:35PM | Duration 9h35 | Departure days Sun | Cheapest price $65 |
Operator FlixBus | Departure Time 10:00AM | Arrival Time 10:00PM | Duration 12h00 | Departure days Sun | Cheapest price $76 |
Operator FlixBus | Departure Time 01:45PM | Arrival Time 02:00AM | Duration 12h15 | Departure days Tue | Cheapest price $58 |
Operator Greyhound | Departure Time 02:30PM | Arrival Time 01:05AM | Duration 10h35 | Departure days Sun | Cheapest price $75 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 02:40AM | Duration 9h25 | Departure days Sun | Cheapest price $65 |
Operator Greyhound | Departure Time 05:50PM | Arrival Time 04:50AM | Duration 11h00 | Departure days Sun | Cheapest price $63 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 03:50AM | Duration 9h20 | Departure days Sun | Cheapest price $65 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 08:50AM | Duration 12h20 | Departure days Thu | Cheapest price $53 |
Operator Greyhound | Departure Time 09:50PM | Arrival Time 08:50AM | Duration 11h00 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $59 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 08:25AM | Duration 10h25 | Departure days Sun | Cheapest price $67 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 02:10PM | Duration 15h40 | Departure days Sun | Cheapest price $79 |
Operator Greyhound | Departure Time 10:50PM | Arrival Time 09:50AM | Duration 11h00 | Departure days Mon, Sat | Cheapest price $79 |
The table below shows live departures for Philadelphia, PA to Durham, NC buses for today, Saturday, July 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:50 PM Philadelphia, PA | 11h00 | 8:50 AM Durham, NC | 0 transfersDirect | |
![]() | 10:50 PM Philadelphia, PA | 11h00 | 9:50 AM Durham, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Philadelphia, PA to Durham, NC run on average 17 times per day, taking around 9h 45m. Cheap bus tickets for this journey start at $53 (€53) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:50, the last at 23:20. The fastest bus covers the 340 miles (548 km) distance in 10h 55m.
Distance 340 miles (548 km) |
Average bus duration 9h 45m |
Cheapest ticket price $53 (€53) |
Buses per day 17 |
Direct buses 1 |
Fastest bus 10h 55m |
First bus 12:50 AM |
Last bus 11:20 PM |
Cheapest Month Aug |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 28 days |
Discover the best of Durham, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Durham, NC trip today.
Major art museum at Duke with global collections, rotating exhibitions, and strong programs in modern and classical art.
Hands-on science museum with aerospace, physics, wildlife, and family exhibits in downtown Durham.
Historic site and museum exploring Washington Duke, tobacco farming, and Durham's industrial origins.
Beloved public garden with terraces, woodland paths, and seasonal blooms, ideal for a scenic walk near Duke.
Lively downtown district for walking among warehouses, public art, music venues, and restored tobacco-era spaces.
Scenic riverside greenway for walking and cycling, connecting downtown with quiet stretches of restored nature.
Eastern North Carolina chopped pork barbecue with a tangy vinegar-pepper sauce. A defining regional staple widely loved across Durham and the Triangle.
Slow-cooked pork shoulder or whole hog, often served on a plate with slaw and hush puppies. It reflects the area’s deep barbecue tradition.
Fried cornmeal batter balls served with barbecue or seafood. They are a classic Southern side found on many Durham menus.
Refined restaurant showcasing seasonal North Carolina ingredients with polished service. Known for elevated Southern cooking and a stylish setting.
Beloved local bakery and café serving excellent pastries, breads, and coffee. A dependable stop for breakfast, lunch, or a quick snack.
Popular casual spot for inventive biscuit sandwiches, shrimp and grits, and Southern brunch favorites in a lively downtown atmosphere.
Moderate for a US college city; hotels and dining are mid-priced, transit is limited, but many casual meals and coffee shops are affordable.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
Find answers to the most common questions about traveling from Philadelphia, PA to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.

Most Philadelphia, PA to Durham, NC buses use the Philadelphia, Schuylkill Ave (Cira Centre South) to Durham, W Pettigrew St (Greyhound Bus Station) station pair. Use this guide to compare Philadelphia, PA and Durham, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need