- Must visit
Nasher Museum of Art
Major art museum at Duke with global collections, rotating exhibitions, and strong programs in modern and classical art.
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The cheapest and fastest buses from Orlando, FL to Durham, NC
Showing times, prices and bookable tickets for Sep 09
Cheapest price on Sep 09
$186
Average ticket price on Sep 09
$186
Fastest journey on Sep 09
17 h 10 m
Average journey duration on Sep 09
17 h 10 m
Buses on Sep 09
1
Distance
861 km
Cheap tickets
The best way to find a cheap bus ticket from Orlando, FL to Durham, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Durham, NC will cost around $186 if you buy it on the day, but the cheapest tickets can be found for only $186.
Fast buses
On Wed, Sep 09, we found 1 buses from Orlando, FL to Durham, NC, including 1 direct services.
On Wed, Sep 09 the direct buses cover the 861 km distance in an average of 17 h 10 m but if you time it right, some buses will get you there in just 17 h 10 m .
On Wed, Sep 09 the slowest buses will take 17 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
8:00 AM17h10Orlando, FL1:10 AMDurham, NC$1861One-way0 transfers
- 8:00 AM17h10Orlando, FL1:10 AMDurham, NC$1861One-way0 transfers
Travel Information
Compare train, bus, and flight for Orlando, FL to Durham, NC
Omio recommends booking the flight as it is the most popular option from Orlando, FL to Durham, NC among Omio's users. If you are prioritising price, take the train, with an average ticket price of $153 For those with little time, consider booking a flight, which has an average total journey time of 6h 30m. Average ticket prices depend on the travel mode: a train costs an average of $153, while a flight costs an average of $635.
Distance: 535 miles (861 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$188 Average price | $635 Average price | $153 Average price Cheapest | $124 Average price (fuel + tolls) |
15h 40m Average total duration 15h 10m Onboard + 30m Additional time* | 6h 30m Average total duration Fastest 4h 30m Onboard + 2h 0m Additional time* | 14h 39m Average total duration 14h 9m Onboard + 30m Additional time* | 8h 51m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Orlando, FL to Durham, NC is a train with an average price of $153.
This is compared to other travel options from Orlando, FL to Durham, NC:
A train is $35 less than a bus for this route with tickets for a bus from Orlando, FL to Durham, NC costing on average $188.
A train is $482 less than a flight for this route with tickets for a flight from Orlando, FL to Durham, NC costing on average $635.
The fastest way to travel from Orlando, FL to Durham, NC is by flight with an average journey time of 4h 30m.
Other travel options to Durham, NC take longer:
Train takes on average 14h 9m.
Bus takes on average 15h 10m.
It's helpful to compare your options as there are 3 ways to travel between Orlando, FL and Durham, NC including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Orlando, FL to Durham, NC among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $188 compared to roughly $124 in fuel and tolls — a saving of about $-63.76. The journey takes 15h 10m versus 8h 51m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Orlando, FL to Durham, NC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:55AM | Arrival Time 09:00PM | Duration 18h05 | Departure days Fri | Cheapest price $206 |
Operator FlixBus | Departure Time 03:55AM | Arrival Time 02:10AM | Duration 22h15 | Departure days Wed, Fri, Sat | Cheapest price $158 |
Operator FlixBus | Departure Time 04:45AM | Arrival Time 09:10PM | Duration 16h25 | Departure days Mon | Cheapest price $94 |
Operator Greyhound | Departure Time 04:45AM | Arrival Time 09:10PM | Duration 16h25 | Departure days Sun | Cheapest price $108 |
Operator Greyhound | Departure Time 06:00AM | Arrival Time 10:00PM | Duration 16h00 | Departure days Mon | Cheapest price $93 |
Operator FlixBus | Departure Time 08:00AM | Arrival Time 01:10AM | Duration 17h10 | Departure days Wed | Cheapest price $186 |
Operator FlixBus | Departure Time 08:45AM | Arrival Time 01:10AM | Duration 16h25 | Departure days Sat | Cheapest price $221 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 02:10AM | Duration 17h10 | Departure days Mon | Cheapest price $92 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 02:10AM | Duration 16h40 | Departure days Sun | Cheapest price $108 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 04:50AM | Duration 16h05 | Departure days Sun | Cheapest price $107 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 09:00AM | Duration 19h00 | Departure days Mon, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 03:45AM | Duration 13h15 | Departure days Mon, Sun | Cheapest price $93 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 04:50AM | Duration 13h10 | Departure days Mon, Sun | Cheapest price $109 |
Operator Greyhound | Departure Time 04:45PM | Arrival Time 06:10PM | Duration 25h25 | Departure days Tue | Cheapest price $319 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 08:50AM | Duration 16h05 | Departure days Fri | Cheapest price $215 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 07:45AM | Duration 13h15 | Departure days Fri | Cheapest price $191 |
Operator FlixBus | Departure Time 06:45PM | Arrival Time 01:00PM | Duration 18h15 | Departure days Tue | Cheapest price $268 |
Operator FlixBus | Departure Time 07:30PM | Arrival Time 08:45AM | Duration 13h15 | Departure days Thu | Cheapest price $157 |
Operator FlixBus | Departure Time 08:40PM | Arrival Time 09:50AM | Duration 13h10 | Departure days Sat | Cheapest price $244 |
Operator Greyhound | Departure Time 08:50PM | Arrival Time 02:10PM | Duration 17h20 | Departure days Sun | Cheapest price $112 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 05:35PM | Duration 18h40 | Departure days Sun | Cheapest price $108 |
Live departures
Orlando, FL to Durham, NC bus times
The table below shows live departures for Orlando, FL to Durham, NC buses for today, Tuesday, September 8. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 4:45 PM Orlando, FL | 25h25 | 6:10 PM Durham, NC | 0 transfersDirect | |
| 6:45 PM Orlando, FL | 18h15 | 1:00 PM Durham, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Orlando, FL to Durham, NC by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Orlando, FL to Durham, NC buses with Omio?
FlixBus operates all buses services from Orlando, FL to Durham, NC.
Omio is an official ticket reseller for all your travel options from Orlando, FL to Durham, NC.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Orlando, FL to Durham, NC.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Orlando, FL to Durham, NC.
Journey information
Overview: Bus from Orlando, FL to Durham, NC
USAUSA
Buses from Orlando, FL to Durham, NC run on average 7 times per day, taking around 15h 10m. Cheap bus tickets for this journey start at $109 but you can travel from only $53 by flight.
The earliest bus runs at 00:50, the last at 23:40. The fastest bus covers the 535 miles (861 km) distance in 10h 40m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $53
Distance 535 miles (861 km) |
Average bus duration 15h 10m |
Cheapest ticket price $109 |
Buses per day 7 |
Fastest bus 10h 40m |
First bus 12:50 AM |
Last bus 11:40 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jul - Sep |
Best time to book 1 day |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $53
Bus providers: FlixBus, Greyhound from Orlando, FL to Durham, NCYou can travel by bus between Orlando, FL to Durham, NC with FlixBus, Greyhound for as low as $53. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
10h 40m
Cheapest FlixBus Price
$109
FlixBus frequency
6 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
15h 50m
Cheapest Greyhound Price
$110
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Durham, NC
Things to do in Durham, NC
Discover the best of Durham, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Durham, NC trip today.
- Must visit
Museum of Life and Science
Hands-on science museum with aerospace, physics, wildlife, and family exhibits in downtown Durham.
- Recommended
Duke Homestead State Historic Site
Historic site and museum exploring Washington Duke, tobacco farming, and Durham's industrial origins.
- Must visit
Sarah P. Duke Gardens
Beloved public garden with terraces, woodland paths, and seasonal blooms, ideal for a scenic walk near Duke.
- Must visit
Downtown Durham
Lively downtown district for walking among warehouses, public art, music venues, and restored tobacco-era spaces.
- Must visit
American Tobacco Trail
Scenic riverside greenway for walking and cycling, connecting downtown with quiet stretches of restored nature.
- Gluten-free
Eastern NC Pork Barbecue
Eastern North Carolina chopped pork barbecue with a tangy vinegar-pepper sauce. A defining regional staple widely loved across Durham and the Triangle.
Pulled Pork Plate
Slow-cooked pork shoulder or whole hog, often served on a plate with slaw and hush puppies. It reflects the area’s deep barbecue tradition.
- Vegetarian
Hush Puppies
Fried cornmeal batter balls served with barbecue or seafood. They are a classic Southern side found on many Durham menus.
M Pocha
Refined restaurant showcasing seasonal North Carolina ingredients with polished service. Known for elevated Southern cooking and a stylish setting.
Guglhupf Bakery & Cafe
Beloved local bakery and café serving excellent pastries, breads, and coffee. A dependable stop for breakfast, lunch, or a quick snack.
True Flavors Diner
Popular casual spot for inventive biscuit sandwiches, shrimp and grits, and Southern brunch favorites in a lively downtown atmosphere.
US Dollar ($)
Moderate for a US college city; hotels and dining are mid-priced, transit is limited, but many casual meals and coffee shops are affordable.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-40 per person for a mid-range meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
FAQs: Bus from Orlando, FL to Durham, NC
Find answers to the most common questions about traveling from Orlando, FL to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Orlando, FL to Durham, NC can start from as little as $109 when you book in advance. The average bus ticket price for Orlando, FL to Durham, NC is $188 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Orlando, FL to Durham, NC is 10h 40m to travel the 535 miles (861 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Orlando, FL to Durham, NC leaves at 12:50 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Orlando, FL to Durham, NC leaves at 11:40 PM.
There are 7 buses a day from Orlando, FL to Durham, NC which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Orlando, FL to Durham, NC, you can count on FlixBus for the best way to get you to Durham, NC. You can also check all possible bus companies who offer a service between Orlando, FL and Durham, NC and compare the amenities they offer before buying a bus ticket.
When departing from Orlando, FL , you have various bus station options to start your journey from including Orlando, N John Young Pkwy (Greyhound Bus Station), Orlando, The Florida Mall, FL, Buena Ventura Lakes, Kissimmee . When arriving in Durham, NC , you can end your journey in bus stations like Durham Station, Chapel Hill, Myrica St / Eubanks Rd, NC .Passengers board the bus most frequently from Orlando, N John Young Pkwy (Greyhound Bus Station), which is located around 1 miles (3 km) away from the city centre, and they get off the bus at Durham Station, located 0 away from the city centre.
A trip to Durham, NC from Orlando, FL is worth doing but not as a day trip with a journey time of 10h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Orlando, FL to Durham, NC is September.
It's helpful to compare your options as there are 3 ways to travel between Orlando, FL and Durham, NC including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Durham, NC:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to Durham, NC for bus company FlixBus.
Whether you can cancel your bus ticket from Orlando, FL to Durham, NC depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Orlando, FL to Durham, NC.
Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Durham, NC:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Durham, NC:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Orlando, FL to Durham, NC. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Orlando, FL to Durham, NC with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Orlando, FL to Durham, NC with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Orlando, FL to Durham, NC with the following bus company: FlixBus.
Since neither Orlando, FL nor Durham, NC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Orlando, FL to Durham, NC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Durham, NC, travelers should stay alert to common urban safety concerns such as petty theft, especially in crowded areas and public transit. Scams may include overcharging by unofficial taxi services or ride-share drivers, so using reputable transportation apps is advised. It's also important to avoid isolated areas after dark and keep personal belongings secure to reduce risk.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Orlando, FL to Durham, NC
Most Orlando, FL to Durham, NC buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Durham, W Pettigrew St (Greyhound Bus Station) station pair. Use this guide to compare Orlando, FL and Durham, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Orlando
Arrival bus stations in Durham
Which Orlando, FL station do buses to Durham, NC leave from?
Buses from Orlando, FL to Durham, NC leave from Orlando, N John Young Pkwy (Greyhound Bus Station). The station is 1 miles (3 km) from Orlando, FL city centre at 555 John Young Pkwy, Orlando, FL 32805, USA.
Orlando, N John Young Pkwy (Greyhound Bus Station)555 John Young Pkwy, Orlando, FL 32805, USA
City-centre transport
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Bus125 · 40m · $2 · every ~6 min
125 · 41m · $2 · every ~6 min
Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Parking, taxis and toilets
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Orlando, The Florida MallOrlando Florida Mall Ave,Florida Mall Ave 1632,32809
City-centre transport
Getting to Orlando, The Florida Mall from Orlando city centre
Bus42 · 26m · $2 · every ~5 min
Durham, W Pettigrew St (Greyhound Bus Station)Durham W Pettigrew St Bus Station,515 W Pettigrew St,27701
City-centre transport
Getting to Durham, W Pettigrew St (Greyhound Bus Station) from Durham city centre
Bus2, 9, 12, 12B · 5m · $1 · every ~12 min
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Durham, NC
Here are some other resources that might have the information you need
Most popular buses to and from Durham, NC and Orlando, FL
Most popular bus connections to Durham, NC
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