The cheapest and fastest trains from Prague to Karlsruhe
Cheapest price
$47
Average price
$121
Fastest journey
8 h 28 m
Average duration
8 h 35 m
Trains per day
10
Distance
452 km
The best way to find a cheap train ticket from Prague to Karlsruhe is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Karlsruhe will cost around $121 if you buy it on the day, but the cheapest tickets can be found for only $47.
It's difficult to get from Prague to Karlsruhe without transferring at least 3 times.
FlixBus+
FlixTrain
EX 358 · 3568 · 88618 · ICE 1064
EX 358 · 3570 · IC 2068
RJ 382 · IC 2442 · ICE 691 · ICE 201
RJ 178 · IC 2440 · ICE 599 · ICE 109
RJ 382 · IC 2442 · ICE 691 · ICE 201
RJ 178 · IC 2440 · ICE 599 · ICE 109
rj 382 · IC 2442 · ICE 691 · ICE 201
EX 358 · 3568 · 88618 · ICE 1064
EC 358 · R 3568 · R 88618 · ICE 1064Travel Information
Compare train and bus for Prague to Karlsruhe
Omio recommends booking the train as it is the most popular option from Prague to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from €25. For those with little time consider booking a bus which can get you there in 7h 6m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €25, and a train costs an average of €28.
Distance: 280 miles (452 km)
Compare train with
Most popular Train | Bus |
|---|---|
€72 Average price | €37 Average price Cheapest |
10h 13m Average total duration 9h 43m Onboard + 30m Additional time* | 7h 36m Average total duration Fastest 7h 6m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.1kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Karlsruhe train times
The table below shows live departures for Prague to Karlsruhe trains for tomorrow, Saturday, January 17. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ FlixTrain | 2:30 AM Prague, Central Train Station | 11h56 | 2:26 PM Karlsruhe Hbf | 1 transfer | |
RJ 178 · IC 2440 · ICE 599 · ICE 109 | On time 7:31 AM Prague hlavní nádraží | 8h28 | 3:59 PM Karlsruhe Hbf | 3 transfers | |
RJ 178 · ICE 1558 · ICE 375 | On time 7:31 AM Prague hlavní nádraží | 9h27 | 4:58 PM Karlsruhe Hbf | 2 transfers | |
EC 358 · R 3568 · R 88618 · ICE 1064 | On time 8:35 AM Prague hlavní nádraží | 8h46 | 5:21 PM Karlsruhe Hbf | 3 transfers | |
EC 358 · R 3568 · IC 2068 | 8:35 AM Prague hlavní nádraží | 9h18 | 5:53 PM Karlsruhe Hbf | 2 transfers | |
EX 358 · 3568 · 88618 · ICE 1064 | On time 8:35 AM Prague hlavní nádraží | 8h46 | 5:21 PM Karlsruhe Hbf | 3 transfers | |
EX 358 · 3570 · IC 2068 | On time 8:35 AM Prague hlavní nádraží | 9h18 | 5:53 PM Karlsruhe Hbf | 2 transfers | |
RJ 382 · ICE 1556 · ICE 377 | On time 9:31 AM Prague hlavní nádraží | 9h28 | 6:59 PM Karlsruhe Hbf | 2 transfers | |
RJ 382 · IC 2442 · ICE 691 · ICE 201 | On time 9:31 AM Prague hlavní nádraží | 8h28 | 5:59 PM Karlsruhe Hbf | 3 transfers | |
rj 382 · IC 2442 · ICE 691 · ICE 201 | 9:31 AM Prague hlavní nádraží | 8h28 | 5:59 PM Karlsruhe Hbf | 3 transfers | |
Find all the dates and times for this journey
Compare prices and tickets Prague to Karlsruhe by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 17
Jan 18
Jan 19
Jan 20
Jan 21
Jan 22
Jan 23
Why should you book Prague to Karlsruhe trains with Omio?
Deutsche Bahn (RE,ICE,IC,EC) as well as ÖBB | Euro City (EC) offer trains services from Prague to Karlsruhe. Omio is an official ticket reseller for all your travel options from Prague to Karlsruhe.
Why book with Omio vs Deutsche Bahn (RE,ICE,IC,EC)?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn (RE,ICE,IC,EC), but also compare tickets for the likes of ÖBB | Euro City (EC) to find the best option for your trip from Prague to Karlsruhe.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn (RE,ICE,IC,EC) with all available travel options, which are train and bus to ensure you get the best deal for traveling from Prague to Karlsruhe.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Deutsche Bahn (RE,ICE,IC,EC) tickets can be bought on Deutsche Bahn (RE,ICE,IC,EC)'s website or third party sellers, Omio allows you to compare with the likes of ÖBB | Euro City (EC) to help you choose the right option for your journey from Prague to Karlsruhe.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Prague to Karlsruhe.
How far in advance should I book train tickets from Prague to Karlsruhe?
Journey information
Overview: Train from Prague to Karlsruhe
Train Ticket Prices
- Budget Options: Train tickets from Prague to Karlsruhe start from as low as $35 (€28) if booked well in advance.
- Standard Fares: Typically, trains cost $89 (€72) depending on the train type and class.
Journey Duration & Frequency
- On average there are 10 daily trains from Prague to Karlsruhe with 0 direct service.
- The fastest trains can take as little as 8h 7m but the average duration is 9h 43m
Train Operators
- Travel from Prague to Karlsruhe with Deutsche Bahn and ÖBB | Euro City (EC)
- The most booked train company for this route on Omio is Deutsche Bahn.
Stations & Schedule
- Most trains depart from Prague hlavní nádraží and arrive in Karlsruhe Hbf
- First train typically departs at 12:11 AM and the last at 11:54 PM
Distance 280 miles (452 km) |
Average train duration 9h 43m |
Cheapest ticket price $35 (€28) |
Trains per day 10 |
Fastest train 8h 7m |
First train 00:11 |
Last train 23:54 |
Train companies: Deutsche Bahn, ÖBB | Euro City (EC) from Prague to Karlsruhe trainsDeutsche Bahn, ÖBB | Euro City (EC) trains will get you between Prague and Karlsruhe from $32 (€25). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
ÖBB | Euro City (EC)
FAQs: Trains from Prague to Karlsruhe
Find answers to the most common questions about traveling from Prague to Karlsruhe by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Karlsruhe, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Prague to Karlsruhe
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
- Monday: 08:00 13:30 - 12:30 18:00
- Tuesday: 08:00 13:30 - 12:30 18:00
- Wednesday: 08:00 13:30 - 12:30 18:00
- Thursday: 08:00 13:30 - 12:30 18:00
- Friday: 08:00 13:30 - 12:30 18:00
- Saturday: 09:00 - 13:00
- Hubraum
- Vogel Hausbräu Durlach
- Asia Gourmet
- Borsalino
- Hotel Große Linde
- Zum Erwin
- Der Blaue Reiter
- Beim Schupi
- Rosenstüble 2.0
- Saloniki
- Rote Taube
- Beim Schupi
More options for your journey from Prague to Karlsruhe
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