The cheapest and fastest trains from Prague to Karlsruhe
Cheapest price
$41
Average price
$66
Fastest journey
8 h 17 m
Average duration
8 h 52 m
Trains per day
5
Distance
452 km
The best way to find a cheap train ticket from Prague to Karlsruhe is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Karlsruhe will cost around $66 if you buy it on the day, but the cheapest tickets can be found for only $41.
Of the 5 trains that leave Prague for Karlsruhe on Wed, Dec 03, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Dec 03 the direct trains cover the 452 km distance in an average of 8 h 52 m but if you time it right, some trains will get you there in just 8 h 17 m .
On Wed, Dec 03 the slowest trains will take 9 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare train and bus for Prague to Karlsruhe
Omio recommends booking the train as it is the most popular option from Prague to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from €25. For those with little time consider booking a bus which can get you there in 7h 6m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €25, and a train costs an average of €28.
Distance: 280 miles (452 km)
Compare train with
Most popular Train | Bus |
|---|---|
€72 Average price | €37 Average price Cheapest |
10h 13m Average total duration 9h 43m Onboard + 30m Additional time* | 7h 36m Average total duration Fastest 7h 6m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.1kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Karlsruhe train times
The table below shows live departures for Prague to Karlsruhe trains for today, Tuesday, December 2. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
EX 358 · ICE 26 · ICE 79 | On time 8:35 AM Prague hlavní nádraží | 9h34 | 6:09 PM Karlsruhe Hbf | 2 transfers | |
EC 358 · RE 3568 · R 88618 · ICE 1064 | On time 8:35 AM Prague hlavní nádraží | 8h45 | 5:20 PM Karlsruhe Hbf | 3 transfers | |
EX 358 · RE 3568 · RE 88618 · ICE 1064 | On time 8:35 AM Prague hlavní nádraží | 8h45 | 5:20 PM Karlsruhe Hbf | 3 transfers | |
EC 356 · RE 3572 · IC 2066 | On time 10:35 AM Prague hlavní nádraží | 9h18 | 7:53 PM Karlsruhe Hbf | 2 transfers | |
EX 356 · RE 3572 · RE 88620 · RE 19028 | On time 10:35 AM Prague hlavní nádraží | 8h50 | 7:25 PM Karlsruhe Hbf | 3 transfers | |
EX 356 · RE 3574 · IC 2066 | On time 10:35 AM Prague hlavní nádraží | 9h18 | 7:53 PM Karlsruhe Hbf | 2 transfers | |
EC 356 · RE 3572 · R 88620 · R 19028 | 10:35 AM Prague hlavní nádraží | 8h50 | 7:25 PM Karlsruhe Hbf | 3 transfers | |
EX 354 · ICE 22 · ICE 273 | On time 12:35 PM Prague hlavní nádraží | 9h46 | 10:21 PM Karlsruhe Hbf | 2 transfers | |
EC 354 · RE 3576 · R 88646 · RB 23448 | On time 12:35 PM Prague hlavní nádraží | 9h12 | 9:47 PM Karlsruhe Hbf | 4 transfers | |
EX 354 · RE 3576 · RE 88646 · RB 23448 | On time 12:35 PM Prague hlavní nádraží | 9h12 | 9:47 PM Karlsruhe Hbf | 4 transfers | |
EX 354 · RE 3576 · ICE 526 · ICE 205 | On time 12:35 PM Prague hlavní nádraží | 9h24 | 9:59 PM Karlsruhe Hbf | 3 transfers | |
EX 352 · RE 3580 · RE 26786 · RB 23450 | On time 2:35 PM Prague hlavní nádraží | 9h12 | 11:47 PM Karlsruhe Hbf | 4 transfers | |
EC 352 · RE 3580 · R 26786 · R 19036 | 2:35 PM Prague hlavní nádraží | 9h44 | 12:19 AM Karlsruhe Hbf | 3 transfers | |
EX 352 · RE 3580 · RE 26786 · RE 19036 | On time 2:35 PM Prague hlavní nádraží | 9h44 | 12:19 AM Karlsruhe Hbf | 3 transfers | |
EC 352 · RE 3580 · R 26786 · RB 23450 | On time 2:35 PM Prague hlavní nádraží | 9h12 | 11:47 PM Karlsruhe Hbf | 4 transfers | |
EX 364 · RE 3584 · RE 88652 · IC 2326 | 4:35 PM Prague hlavní nádraží | 9h52 | 2:27 AM Karlsruhe Hbf | 3 transfers | |
R 756 · Os 7554+ 83952+ RE 4093 | On time 5:05 PM Prague hlavní nádraží | 13h20 | 6:25 AM Karlsruhe Hbf | 6 transfers | |
R 756 · Os 7554+ 83952+ RE 4093 | On time 5:05 PM Prague hlavní nádraží | 13h48 | 6:53 AM Karlsruhe Hbf | 5 transfers | |
R 676 · RB 28015 · S 1 · RE 16536 | 5:45 PM Prague hlavní nádraží | 14h13 | 7:58 AM Karlsruhe Hbf | 7 transfers | |
R 676 · RB 28015 · S 1 · RE 16536 | 5:45 PM Prague hlavní nádraží | 14h24 | 8:09 AM Karlsruhe Hbf | 6 transfers | |
R 672 · Bus U28 · Bus S1 · IC 2044 | 7:45 PM Prague hlavní nádraží | 16h02 | 11:47 AM Karlsruhe Hbf | 7 transfers | |
R 672 · Bus U28 · S 1 · ICE 1654 | On time 7:45 PM Prague hlavní nádraží | 16h06 | 11:51 AM Karlsruhe Hbf | 4 transfers | |
R 672 · Bus U28 · Bus S1 · IC 2044 | On time 7:45 PM Prague hlavní nádraží | 15h59 | 11:44 AM Karlsruhe Hbf | 8 transfers | |
R 670 · Sp 1940 · Os 7050 · Os 7020 | On time 10:35 PM Prague hlavní nádraží | 13h23 | 11:58 AM Karlsruhe Hbf | 8 transfers | |
R 670 · Sp 1940 · Os 7050 · Os 7020 | On time 10:35 PM Prague hlavní nádraží | 13h34 | 12:09 PM Karlsruhe Hbf | 7 transfers | |
R 670 · Os 28017 · S 1 · IC 2046 | On time 10:35 PM Prague hlavní nádraží | 14h23 | 12:58 PM Karlsruhe Hbf | 5 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Karlsruhe by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 03
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Dec 23
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Journey information
Overview: Train from Prague to Karlsruhe
Trains from Prague to Karlsruhe run on average 10 times per day, taking around 9h 43m. Cheap train tickets for this journey start at $35 (€28) but you can travel from only $32 (€25) by bus.
The earliest train runs at 00:11, the last at 23:54. The fastest train covers the 280 miles (452 km) distance in 8h 7m.
Distance 280 miles (452 km) |
Average train duration 9h 43m |
Cheapest ticket price $35 (€28) |
Trains per day 10 |
Fastest train 8h 7m |
First train 00:11 |
Last train 23:54 |
Train companies: Deutsche Bahn, ÖBB | Euro City (EC) from Prague to Karlsruhe trainsDeutsche Bahn, ÖBB | Euro City (EC) trains will get you between Prague and Karlsruhe from $32 (€25). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
ÖBB | Euro City (EC)
FAQs: Trains from Prague to Karlsruhe
Find answers to the most common questions about traveling from Prague to Karlsruhe by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Karlsruhe, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Prague to Karlsruhe
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
- Beim Schupi
- Rosenstüble 2.0
- Saloniki
- Rote Taube
- Beim Schupi
- Monday: 08:00 13:30 - 12:30 18:00
- Tuesday: 08:00 13:30 - 12:30 18:00
- Wednesday: 08:00 13:30 - 12:30 18:00
- Thursday: 08:00 13:30 - 12:30 18:00
- Friday: 08:00 13:30 - 12:30 18:00
- Saturday: 09:00 - 13:00
- Hubraum
- Vogel Hausbräu Durlach
- Asia Gourmet
- Borsalino
- Hotel Große Linde
- Zum Erwin
- Der Blaue Reiter
More options for your journey from Prague to Karlsruhe
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