The cheapest and fastest buses from Prague to Karlsruhe
Cheapest price
$36
Average price
$41
Fastest journey
8 h 40 m
Average duration
9 h 4 m
Buses per day
5
Distance
452 km
The best way to find a cheap bus ticket from Prague to Karlsruhe is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Karlsruhe will cost around $41 if you buy it on the day, but the cheapest tickets can be found for only $36.
Of the 5 buses that leave Prague for Karlsruhe on Mon, Dec 01, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Dec 01 the direct buses cover the 452 km distance in an average of 9 h 4 m but if you time it right, some buses will get you there in just 8 h 40 m .
On Mon, Dec 01 the slowest buses will take 9 h 21 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare train and bus for Prague to Karlsruhe
Omio recommends booking the train as it is the most popular option from Prague to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from €25. For those with little time consider booking a bus which can get you there in 7h 6m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €25, and a train costs an average of €28.
Distance: 280 miles (452 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€37 Average price Cheapest | €72 Average price |
7h 36m Average total duration Fastest 7h 6m Onboard + 30m Additional time* | 10h 13m Average total duration 9h 43m Onboard + 30m Additional time* |
0.5 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Prague to Karlsruhe Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:50AM | Arrival Time 03:15PM | Duration 11h25 | Departure days Thu, Fri, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 04:10AM | Arrival Time 03:15PM | Duration 11h05 | Departure days Thu, Fri, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 06:40AM | Arrival Time 03:15PM | Duration 8h35 | Departure days Thu, Fri, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 07:35AM | Arrival Time 07:06PM | Duration 11h31 | Departure days Thu, Fri, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 07:55AM | Arrival Time 07:06PM | Duration 11h11 | Departure days Thu, Fri, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 07:35PM | Duration 10h35 | Departure days Thu, Fri, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 07:35PM | Duration 9h55 | Departure days Thu, Fri, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 10:30AM | Arrival Time 09:20PM | Duration 10h50 | Departure days Thu, Fri, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 09:20PM | Duration 10h25 | Departure days Thu, Fri, Sun | Cheapest price $65 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 09:55PM | Duration 9h05 | Departure days Thu, Fri, Sun | Cheapest price $52 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 11:50PM | Duration 10h55 | Departure days Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 09:55PM | Duration 8h50 | Departure days Thu, Fri, Sun | Cheapest price $52 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 11:50PM | Duration 9h20 | Departure days Thu, Fri, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 11:50PM | Duration 8h45 | Departure days Thu | Cheapest price $52 |
Operator FlixBus | Departure Time 03:10PM | Arrival Time 11:50PM | Duration 8h40 | Departure days Thu, Fri, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 03:40AM | Duration 10h25 | Departure days Thu, Fri, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 07:25PM | Arrival Time 06:35AM | Duration 11h10 | Departure days Thu | Cheapest price $120 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 06:35AM | Duration 10h15 | Departure days Thu, Fri, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 06:35AM | Duration 10h10 | Departure days Fri | Cheapest price $58 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 09:27AM | Duration 12h02 | Departure days Thu, Fri | Cheapest price $51 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 09:27AM | Duration 11h37 | Departure days Thu, Fri, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 09:55PM | Arrival Time 06:35AM | Duration 8h40 | Departure days Thu, Fri, Sun | Cheapest price $48 |
Operator FlixBus | Departure Time 10:15PM | Arrival Time 06:35AM | Duration 8h20 | Departure days Thu, Fri, Sun | Cheapest price $48 |
Operator FlixBus | Departure Time 10:25PM | Arrival Time 06:35AM | Duration 8h10 | Departure days Sun | Cheapest price $128 |
Live departures
Prague to Karlsruhe bus times
The table below shows live departures for Prague to Karlsruhe buses for today, Sunday, November 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 7:20 PM Prague, Central Train Station | 10h15 | 5:35 AM Karlsruhe Hbf | 1 transfer | |
FlixBus+ FlixTrain | 8:50 PM Praha, Na Knížecí | 11h37 | 8:27 AM Karlsruhe Hbf | 1 transfer | |
FlixBus | 8:55 PM Praha, ÚAN Florenc | 8h40 | 5:35 AM Karlsruhe Hbf | 0 transfersDirect | |
FlixBus | 9:15 PM Praha, Na Knížecí | 8h20 | 5:35 AM Karlsruhe Hbf | 0 transfersDirect | |
FlixBus · FlixBus | 9:25 PM Praha, Zličín | 8h10 | 5:35 AM Karlsruhe Hbf | 1 transfer | |
![]() | 5:55 AM Prague | 9h21 | 3:16 PM Karlsruhe | 0 transfersDirect | |
![]() | 12:30 PM Prague | 9h20 | 9:50 PM Karlsruhe | 0 transfersDirect | |
![]() | 5:25 PM Prague | 11h10 | 4:35 AM Karlsruhe | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Karlsruhe by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 01
Dec 02
Dec 03
Dec 04
Dec 05
Dec 06
Dec 07
Dec 08
Dec 09
Dec 10
Dec 11
Dec 12
Dec 13
Dec 14
Journey information
Overview: Bus from Prague to Karlsruhe
Buses from Prague to Karlsruhe run on average 20 times per day, taking around 7h 6m. Cheap bus tickets for this journey start at $31 (€25) if you book in advance.
There are 8 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 280 miles (452 km) distance in 8h 35m.
Distance 280 miles (452 km) |
Average bus duration 7h 6m |
Cheapest ticket price $31 (€25) |
Buses per day 20 |
Direct buses 8 |
Fastest bus 8h 35m |
First bus 00:05 |
Last bus 23:55 |
Bus providers: FlixBus, BlaBlaCar from Prague to KarlsruheYou can travel by bus between Prague to Karlsruhe with FlixBus, BlaBlaCar for as low as $31 (€25). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
FAQs: Bus from Prague to Karlsruhe
Find answers to the most common questions about traveling from Prague to Karlsruhe by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Karlsruhe, this guide helps you travel smarter and with confidence.

Passengers board the bus most frequently from Prague, Central Train Station, which is located around 1.8 miles (2.9 km) away from the city centre, and they get off the bus at Karlsruhe Hbf, located 1.7 miles (2.8 km) away from the city centre.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Prague to Karlsruhe, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Prague to Karlsruhe
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- 00:00-23:59
- Free Wi-Fi
- Cafeteria Černý Most (in the station)
- Czech Bistro (in the station)
- Fast Food Express (in the station).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 177, 195, 201 Metro: B
- Bus: 131, 174, 180 Metro: A Train: S4, S5
More options for your journey from Prague to Karlsruhe
Here are some other resources that might have the information you need


