- Must visit
Pinacoteca di Brera
One of Italy’s leading art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the elegant Brera district.
Cheapest price
$227
Average price
$238
Fastest journey
21 h 24 m
Average duration
1 d 1 h 24 m
Trains per day
2
Distance
646 km
The best way to find a cheap train ticket from Prague to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Milan will cost around $238 if you buy it on the day, but the cheapest tickets can be found for only $227.
It's difficult to get from Prague to Milan without transferring at least 3 times.




Omio recommends booking the flight as it is the most popular option from Prague to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $58. For those with little time consider booking a flight which can get you there in 2h 38m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.6 - 1.6kg. The ticket price range depends on the travel mode: a bus costs an average of $58, and a flight costs an average of $34.
Distance: 401 miles (646 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$133 Average price | $177 Average price | $85 Average price Cheapest | $264 Average price (fuel + tolls) |
14h 39m Average total duration 14h 9m Onboard + 30m Additional time* | 5h 38m Average total duration Fastest 2h 38m Onboard + 3h 0m Additional time* | 16h 25m Average total duration 15h 55m Onboard + 30m Additional time* | 9h 2m Average total duration (door-to-door) |
- CO2 emissions | 1.9 - 3.9kg CO2 emissions | 0.6 - 1.6kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Milan:
A bus is $48 (€39) less than a train for this route with tickets for a train from Prague to Milan costing on average $133 (€108).
A bus is $91 (€74) less than a flight for this route with tickets for a flight from Prague to Milan costing on average $177 (€143).
Other travel options to Milan take longer:
Train takes on average 14h 9m.
Bus takes on average 15h 55m.
Tickets start at around $133 (€108) compared to roughly $264 (€213) in fuel and tolls — a saving of about $130 (€105). The journey takes 14h 9m versus 9h 2m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Prague to Milan trains for tomorrow, Thursday, May 28. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:21 AM Prague | 29h24 | 11:45 AM Milan | 3 transfers | |
![]() | 2:21 PM Prague | 21h24 | 11:45 AM Milan | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Prague to Milan run on average 3 times per day, taking around 14h 9m. Cheap train tickets for this journey start at $129 (€104) but you can travel from only $34 (€27) by flight.
The earliest train runs at 00:15, the last at 23:57. The fastest train covers the 401 miles (646 km) distance in 14h 9m.
Distance 401 miles (646 km) |
Average train duration 14h 9m |
Cheapest ticket price $129 (€104) |
Trains per day 3 |
Fastest train 14h 9m |
First train 12:15 AM |
Last train 11:57 PM |
Cheapest Month Sep |
Cheapest Day Fri |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 7 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
One of Italy’s leading art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the elegant Brera district.
A major museum of 20th-century Italian art facing Piazza del Duomo, with strong Futurist holdings and striking city views.
A contemporary museum focused on world cultures and major temporary exhibitions, popular for its modern architecture and changing shows.
Milan’s canal district, best known for waterside walks, photogenic bridges, and lively atmosphere day and night.
A charming historic neighborhood of narrow streets, galleries, boutiques, and classic Milan character, ideal for wandering.
Milan’s main square and the symbolic heart of the city, surrounded by major landmarks and constant urban energy.
Creamy saffron risotto, one of Milan's signature dishes, prized for its rich flavor and golden color.
Braised veal shank cooked slowly until tender, traditionally served with gremolata and often paired with risotto.
Breaded veal cutlet fried in butter, a classic Milanese specialty and one of the city's most famous dishes.
Celebrated fine dining restaurant offering creative haute cuisine with an elegant, Michelin-starred reputation.
Famous central bakery known for panzerotti, a beloved casual stop near the Duomo with constant local appeal.
Modern Milanese restaurant known for refined Lombard classics in a stylish contemporary setting.
Milan is pricier than most Italian cities, especially for hotels, central dining, and aperitivo areas.
Service is often included or covered by coperto. Tipping is not required, but rounding up or leaving EUR 1-5 for good service is appreciated. Taxis can be rounded up.
Official public transport app
Milan Centrale, Milan -> Duomo di Milano, Milan
Find answers to the most common questions about traveling from Prague to Milan by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

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