- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Cheapest price
$111
Average price
$166
Fastest journey
11 h 4 m
Average duration
11 h 4 m
Trains per day
17
Distance
717 km
The best way to find a cheap train ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Brussels will cost around $166 if you buy it on the day, but the cheapest tickets can be found for only $111.
It's difficult to get from Prague to Brussels without transferring at least 3 times.
R 676 · Os 28015 · S1 · 16538
rj 176 · ICE 554 · ICE 318
rj 178 · IC 2440 · ICE 2589 · ICE 12
rj 384 · IC 2048 · ICE 2587 · ICE 14
rj 382 · IC 2442 · ICE 2591 · ICE 10
rj 178 · IC 2440 · ICE 2589 · ICE 12
rj 384 · IC 2048 · ICE 2587 · ICE 14
rj 382 · IC 2442 · ICE 2591 · ICE 10
RJ 382 · IC 2442 · ICE 2591 · ICE 10
RJ 178 · IC 2440 · ICE 2589 · ICE 12Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $49. For those with little time consider booking a flight which can get you there in 3h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $49, and a flight costs an average of $26.
Distance: 445 miles (717 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$123 Average price | $155 Average price | $84 Average price Cheapest | $183 Average price (fuel + tolls) |
12h 20m Average total duration 11h 50m Onboard + 30m Additional time* | 6h 21m Average total duration Fastest 3h 21m Onboard + 3h 0m Additional time* | 15h 24m Average total duration 14h 54m Onboard + 30m Additional time* | 8h 49m Average total duration (door-to-door) |
0.2 - 0.6kg CO2 emissions Lowest | 2.2 - 4.3kg CO2 emissions | 0.7 - 1.8kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Brussels:
A bus is $39 (€32) less than a train for this route with tickets for a train from Prague to Brussels costing on average $123 (€101).
A bus is $71 (€58) less than a flight for this route with tickets for a flight from Prague to Brussels costing on average $155 (€127).
Other travel options to Brussels take longer:
Train takes on average 11h 50m.
Bus takes on average 14h 54m.
Tickets start at around $123 (€101) compared to roughly $183 (€150) in fuel and tolls — a saving of about $59 (€49). The journey takes 11h 50m versus 8h 49m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Direct services run with Alibus.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Prague to Brussels trains for today, Thursday, July 30. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
NJ 456 · ICE 1654 · ICE 314 | Delayed 1:53 AM 3:14 AMPrague hlavní nádraží | 12h21 | 2:23 PM 2:23 PMBrussels-Midi | 2 transfers | |
| Friday, July 31 | |||||
rj 384 · IC 2048 · ICE 2587 · ICE 14 | Delayed 6:31 AM Prague hlavní nádraží | 11h04 | 4:28 PM 4:28 PMBrussels-Midi | 3 transfers | |
RJ 384 · IC 2048 · ICE 2587 · ICE 14 | Delayed 6:31 AM Prague hlavní nádraží | 11h04 | 4:28 PM 4:28 PMBrussels-Midi | 3 transfers | |
rj 384 · ICE 1650 · ICE 12 | Delayed 6:31 AM Prague hlavní nádraží | 13h04 | 6:29 PM 6:29 PMBrussels-Midi | 2 transfers | |
RJ 384 · ICE 650 · ICE 12 | Delayed 6:31 AM Prague hlavní nádraží | 13h04 | 6:29 PM 6:29 PMBrussels-Midi | 2 transfers | |
EX 360 · 3564 · ICE 628 · ICE 122 | Delayed 7:35 AM Prague hlavní nádraží | 12h00 | 6:29 PM 6:29 PMBrussels-Midi | 4 transfers | |
rj 178 · IC 2440 · ICE 2589 · ICE 12 | Delayed 8:31 AM Prague hlavní nádraží | 11h04 | 6:29 PM 6:29 PMBrussels-Midi | 3 transfers | |
RJ 178 · IC 2440 · ICE 2589 · ICE 12 | Delayed 8:31 AM Prague hlavní nádraží | 11h04 | 6:29 PM 6:29 PMBrussels-Midi | 3 transfers | |
EX 358 · 3568 · ICE 624 · ICE 224 | Delayed 9:35 AM Prague hlavní nádraží | 12h00 | 8:27 PM 8:27 PMBrussels-Midi | 4 transfers | |
rj 382 · IC 2442 · ICE 2591 · ICE 10 | Delayed 10:31 AM Prague hlavní nádraží | 11h04 | 8:27 PM 8:27 PMBrussels-Midi | 3 transfers | |
RJ 382 · IC 2442 · ICE 2591 · ICE 10 | Delayed 10:31 AM Prague hlavní nádraží | 11h04 | 8:27 PM 8:27 PMBrussels-Midi | 3 transfers | |
RJ 176 · ICE 554 · ICE 318 | On time 12:31 PM Prague hlavní nádraží | 11h23 | 11:54 PM Brussels-Midi | 2 transfers | |
rj 176 · ICE 554 · ICE 318 | On time 12:31 PM Prague hlavní nádraží | 11h23 | 11:54 PM Brussels-Midi | 2 transfers | |
RJ 176 · IC 2444 · ICE 2593 · ICE 318 | On time 12:31 PM Prague hlavní nádraží | 11h23 | 11:54 PM Brussels-Midi | 3 transfers | |
rj 176 · ICE 544 · ICE 318 | On time 12:31 PM Prague hlavní nádraží | 11h23 | 11:54 PM Brussels-Midi | 2 transfers | |
EC 458 · ICE 699 · ICE 18 | On time 6:31 PM Prague hlavní nádraží | 15h04 | 9:35 AM Brussels-Midi | 2 transfers | |
R 676 · Os 28015 · S1 · 16538 | On time 6:47 PM Prague hlavní nádraží | 16h48 | 11:35 AM Brussels-Midi | 6 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Prague to Brussels run on average 7 times per day, taking around 11h 50m. Cheap train tickets for this journey start at $16 (€13) if you book in advance.
The earliest train runs at 00:10, the last at 23:55. The fastest train covers the 445 miles (717 km) distance in 11h 4m.
Distance 445 miles (717 km) |
Average train duration 11h 50m |
Cheapest ticket price $16 (€13) |
Trains per day 7 |
Fastest train 11h 4m |
First train 12:10 AM |
Last train 11:55 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Sat |
Best time to book 77 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels-Midi -> Brussels-Central
Find answers to the most common questions about traveling from Prague to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Prague to Brussels trains use the Praha hlavní nádraží to Bruxelles-Midi station pair, with some services arriving at Bruxelles-Central. Use this guide to compare Prague and Brussels train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Kotleta, Café Imperial
Free. ATMs are available in the train station.
Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.
Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.
Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.
Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Na Kovárně, Cross Club
Free. ATMs are available in the train station.
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Available at Praha-Holesovice: Parking, Taxis, WC.
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Bruxelles-Midi has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Pullman Hotel Bar, Quick Gare du Midi, Subway, EXKi Zuid, Starbucks, Häagen-Dazs, Sbarro, The Coffee Club, The Belgian Chocolate House, PAUL, & many more
Wi-Fi is available for a fee. ATMs are available at Bruxelles-Midi.
Ticket office support is available at Bruxelles-Midi. Information desks are located in the main concourse and next to the international platforms.
Luggage storage is baggage storage facility is located across from the Thalys business lounge.
Available at Bruxelles-Midi: Parking, Taxis, WC.
Available at Bruxelles-Midi: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Bruxelles-Midi: Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Nearby hotels include Les Lofts De Styliste, Park Inn by Radisson Brussels Midi, Pullman Brussels Centre Midi.
Bruxelles-Central has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Starbucks, Brasserie 28 Brewery, Panos, Delitraiteur Eat & Go
Free Wi-Fi available in Starbucks. ATMs are aTM machine is downstairs from the main entrance on the right side.
The ticket office is open Mon - Sun: 06:15 - 22:00. Information desks are travel Center / information desk is located on the left side from the main entrance.
Luggage storage is luggage lockers are located on Level 0 near Platforms 1 and 2.
Available at Bruxelles-Central: Parking, Taxis, WC.
Available at Bruxelles-Central: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Bruxelles-Central: Station has a wide range of facilities for passengers with limited mobility: elevators and escalators to platforms, wheelchair lifts and mobile ramps, barrier-free toilets and accessible parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Nearby hotels include Hilton Brussels Grand Palace, Hotel NH Brussels Carrefour de l'Europe, Hôtel The Moon.
Bruxelles-Congres has practical services for this route, including Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Bike Parking, and Bike Rental.
Food and drink options are available at Bruxelles-Congres.
ATMs are available at Bruxelles-Congres.
Available at Bruxelles-Congres: Parking, Taxis, WC.
Available at Bruxelles-Congres: Bike Parking, Bike Rental.
Accessibility facilities are available at Bruxelles-Congres.
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