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The cheapest and fastest trains from Prague to Brussels
Showing times and prices for Dec 17
Cheapest price
$118
Average price
$142
Fastest journey
10 h 55 m
Average duration
10 h 58 m
Trains per day
14
Distance
717 km
Cheap tickets
The best way to find a cheap train ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Brussels will cost around $142 if you buy it on the day, but the cheapest tickets can be found for only $118.
Fast trains
It's difficult to get from Prague to Brussels without transferring at least 2 times.
rj 382 · ICE 556 · ICE 1010:31AM10h55
Prague hlavní nádraží09:26PMBrussels-North
$1181One-way
2 transfers
rj 176 · ICE 554 · ICE 31812:31PM10h55
Prague hlavní nádraží11:26PMBrussels-North
$1181One-way
2 transfers
rj 178 · ICE 558 · ICE 1208:31AM10h55
Prague hlavní nádraží07:26PMBrussels-North
$1181One-way
2 transfers
RJ 176 · ICE 554 · ICE 31812:31PM11h04
Prague hlavní nádraží11:35PMBrussels-Midi
$1381One-way
2 transfers
rj 178 · ICE 558 · ICE 12 · R 399008:31AM11h03
Prague hlavní nádraží07:34PMBrussels-Central
$1471One-way
3 transfers
rj 382 · ICE 556 · ICE 1010:31AM10h55
Prague hlavní nádraží09:26PMBrussels-North
$1181One-way
2 transfers
rj 176 · ICE 554 · ICE 31812:31PM10h55
Prague hlavní nádraží11:26PMBrussels-North
$1181One-way
2 transfers
rj 178 · ICE 558 · ICE 1208:31AM10h55
Prague hlavní nádraží07:26PMBrussels-North
$1181One-way
2 transfers
rj 178 · ICE 558 · ICE 12 · R 399008:31AM11h03
Prague hlavní nádraží07:34PMBrussels-Central
$1471One-way
3 transfers
rj 382 · ICE 556 · ICE 10 · R 399210:31AM11h03
Prague hlavní nádraží09:34PMBrussels-Central
$1471One-way
3 transfers
Travel Information
Compare train, bus, and flight for Prague to Brussels
Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €27. For those with little time consider booking a flight which can get you there in 2h 27m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €27, and a flight costs an average of €34.
Distance: 445 miles (717 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
€161 Average price | €192 Average price | €66 Average price Cheapest |
13h 42m Average total duration 13h 12m Onboard + 30m Additional time* | 5h 27m Average total duration Fastest 2h 27m Onboard + 3h 0m Additional time* | 14h 9m Average total duration 13h 39m Onboard + 30m Additional time* |
0.2 - 0.6kg CO2 emissions Lowest | 2.2 - 4.3kg CO2 emissions | 0.7 - 1.8kg CO2 emissions |
Most popular train company |  Most popular airline |  Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Brussels train times
The table below shows live departures for Prague to Brussels trains for today, Tuesday, December 16. You can also manually refresh the results below to see updated train journeys.
Last updated at 12:01 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| EC 335 · NJ 468 | 1:21 PM Prague hlavní nádraží | 19h25 | 8:46 AM Brussels-North | 1 transfer | |
 452 | 5:00 PM Prague hlavní nádraží | 15h27 | 8:27 AM Brussels-Midi | 0 transfersDirect | |
| Wednesday, December 17 | |||||
| rj 178 · ICE 558 · ICE 12 · R 3990 | 7:31 AM Prague hlavní nádraží | 11h03 | 6:34 PM Brussels-Central | 3 transfers | |
| RJ 178 · ICE 558 · ICE 12 | On time 7:31 AM Prague hlavní nádraží | 11h04 | 6:35 PM Brussels-Midi | 2 transfers | |
| rj 178 · ICE 558 · ICE 12 | 7:31 AM Prague hlavní nádraží | 10h55 | 6:26 PM Brussels-North | 2 transfers | |
| rj 178 · ICE 558 · ICE 12 · R 1790 | 7:31 AM Prague hlavní nádraží | 11h18 | 6:49 PM Brussels Congress | 3 transfers | |
| rj 178 · ICE 558 · ICE 12 · R 3990 | 7:31 AM Prague hlavní nádraží | 11h13 | 6:44 PM Brussels Congress | 4 transfers | |
| RJ 382 · ICE 556 · ICE 10 | On time 9:31 AM Prague hlavní nádraží | 11h04 | 8:35 PM Brussels-Midi | 2 transfers | |
| rj 382 · ICE 556 · ICE 10 · R 1993 | 9:31 AM Prague hlavní nádraží | 11h44 | 9:15 PM Brussels Congress | 3 transfers | |
| rj 382 · ICE 556 · ICE 10 · R 3992 | 9:31 AM Prague hlavní nádraží | 11h03 | 8:34 PM Brussels-Central | 3 transfers | |
| rj 382 · ICE 556 · ICE 10 | 9:31 AM Prague hlavní nádraží | 10h55 | 8:26 PM Brussels-North | 2 transfers | |
| rj 382 · ICE 556 · ICE 10 · R 3992 | 9:31 AM Prague hlavní nádraží | 11h13 | 8:44 PM Brussels Congress | 4 transfers | |
| RJ 176 · ICE 554 · ICE 318 | 11:31 AM Prague hlavní nádraží | 11h04 | 10:35 PM Brussels-Midi | 2 transfers | |
| rj 176 · ICE 554 · ICE 318 | 11:31 AM Prague hlavní nádraží | 10h55 | 10:26 PM Brussels-North | 2 transfers | |
| rj 176 · ICE 554 · ICE 318 · IC 4544 | 11:31 AM Prague hlavní nádraží | 11h05 | 10:36 PM Brussels-Central | 3 transfers | |
| rj 176 · ICE 554 · ICE 318 · IC 4544 | 11:31 AM Prague hlavní nádraží | 11h13 | 10:44 PM Brussels Congress | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Prague to Brussels trains with Omio?
Deutsche Bahn (ICE,EC,IC,RE,RB) as well as European Sleeper offer trains services from Prague to Brussels. Omio is an official ticket reseller for all your travel options from Prague to Brussels.
Why book with Omio vs Deutsche Bahn (ICE,EC,IC,RE,RB)?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn (ICE,EC,IC,RE,RB), but also compare tickets for the likes of European Sleeper to find the best option for your trip from Prague to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn (ICE,EC,IC,RE,RB) with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Brussels.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Deutsche Bahn (ICE,EC,IC,RE,RB) tickets can be bought on Deutsche Bahn (ICE,EC,IC,RE,RB)'s website or third party sellers, Omio allows you to compare with the likes of European Sleeper to help you choose the right option for your journey from Prague to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Brussels.
How far in advance should I book train tickets from Prague to Brussels?
The best time to book your train from Prague to Brussels is 77 days before departure. See how prices for trains change on the Prague to Brussels route.
Prices are for one-way tickets for one passenger from Prague to Brussels per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from Prague to Brussels.
Trains
from $109Buses
from $71Flights
from $234Journey information
Overview: Train from Prague to Brussels
Czechia
Belgium
Trains from Prague to Brussels run on average 5 times per day, taking around 13h 12m. Cheap train tickets for this journey start at $110 (€88) but you can travel from only $34 (€27) by bus.
The earliest train runs at 00:10, the last at 23:50. The fastest train covers the 445 miles (717 km) distance in 10h 55m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $34 (€27)
Distance 445 miles (717 km) |
Average train duration 13h 12m |
Cheapest ticket price $110 (€88) |
Trains per day 5 |
Fastest train 10h 55m |
First train 00:10 |
Last train 23:50 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $34 (€27)
Train companies: Deutsche Bahn, European Sleeper from Prague to Brussels trainsDeutsche Bahn, European Sleeper trains will get you between Prague and Brussels from $34 (€27). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Duration
10h 55m
Cheapest Price
$125 (€100)
Deutsche Bahn frequency
4 a day
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone
European Sleeper
About
European Sleeper is a Belgian-Dutch train company launched in 2021, operating night train services between Germany and Belgium three times a week, with plans to expand to daily service and extend routes to cities such as Dresden and Prague. Passengers can choose from standard seats, couchettes, or sleeper cabins. Couchettes include free drinks and power outlets, while sleeper cabins offer power outlets and complimentary meals. All tickets are sold as Flex Night fares, which are non-exchangeable but can be canceled up to 48 hours before departure.
Luggage & cancellation policy
Average Duration
15h 25m
Cheapest Price
$63 (€50)
European Sleeper frequency
1 a day
Luggage included
1 piece of hand luggage and 2 pieces of hold luggage included in ticket price
Luggage storage
Luggage racks above seats and at end of carriages
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car serving breakfast, drinks and snacks available for purchase
Seat reservation
Seat or berth reservation mandatory and included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces available, accessible toilets, staff assistance
Pets
Small pets in carriers allowed for free, larger dogs require paid ticket
Quiet zone
FAQs: Trains from Prague to Brussels
Find answers to the most common questions about traveling from Prague to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
Train ticket prices from Prague to Brussels can vary. The cheapest ticket starts at $110 (€88), while the average price is around $202 (€161).
For a fulfilling experience in Brussels, plan on spending 2 to 3 days to explore key attractions such as the Grand Place, Atomium, and various museums, as well as to enjoy the local cuisine and vibrant neighborhoods.
The cheapest way to get from Prague to Brussels is by bus, with a cost of around $34 (€27).
The train from Prague to Brussels takes 10h 55m and runs 5 per day.
In Brussels, explore the vibrant Marolles district with its antique shops and street art, and enjoy a stroll through Parc du Cinquantenaire with its impressive arches and museums. Sample Belgian chocolates at the city's renowned chocolatiers, and experience the lively Saint-Géry district's trendy bars and cafes. Attend a performance at the historic La Monnaie opera house. Don't miss top sights like the opulent Grand Place, Atomium for panoramic views, the iconic Manneken Pis statue, the Royal Palace of Brussels, and the Magritte Museum.
The Prague to Brussels train journey offers scenic views, especially as it passes through the picturesque landscapes of the Czech Republic and parts of Germany, showcasing rolling hills, charming villages, and lush forests. However, urban and industrial areas also feature along the route, particularly as the train approaches Brussels.
A day trip from Prague to Brussels is not feasible, as the journey takes 10h 55m and covers 445 miles (717 km). Trains operate 5 times per day.
The train station in Prague that goes to Brussels is Prague hlavní nádraží, which connects to Brussels-Midi.
The distance by train from Prague to Brussels is 445 miles (717 km).
Yes, you can take the train from Prague to Brussels.
The first train from Prague to Brussels leaves at 12:10 AM.
The last train from Prague to Brussels leaves at 11:50 PM.
Yes, there is a direct train from Prague to Brussels. This service operates 0 times per day, provided by European Sleeper, European Sleeper.
Yes, there is a night train from Prague to Brussels.
popular train stations
Popular train stations from Prague to Brussels
Prague
Brussels
The major train station for departures in Prague is Praha hlavní nádraží. Find all the information you need to know about services, amenities and connections at Praha hlavní nádraží for your trip from Prague to Brussels.
Amenities at train station
Wifi
Lockers
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Shower
Lounge
Lost and Found Office
Ticket Office
Bike Parking
Bike Rental
Car Rental
Information Desk
Luggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
1 km
Number of platforms
7Wifi
- Free
Parking
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
Dining
- Restaurant Fantova Kavárna
- Sushi Time
Taxis
- Outside the main entrance.
Accessibility
- Elevators, ramps.
WC
- CZK 10
Hotel
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
Shower
- Cost CZK 100
Lounge
- Located in the main hall
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Europcar
- Hertz
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
Public transit options for Praha hlavní nádraží
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
Praha Masarykovo Nádraží
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Number of platforms
5Wifi
- Free
Parking
- Parking is available nearby with several public parking options.
Dining
- Restaurant Kotleta
- Café Imperial
Taxis
- Outside the main entrance.
Accessibility
- Ramps.
WC
- CZK 10
Hotel
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Europcar
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
Public transit options for Praha Masarykovo Nádraží
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
Praha-Holesovice
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
2 kmNumber of platforms
4Wifi
- Free
Parking
- Parking is available 24/7 with access from Partyzánská street.
Dining
- Restaurant Na Kovárně
- Cross Club
Taxis
- Outside the main entrance.
Accessibility
- Ramps, restrooms.
WC
- CZK 10
Hotel
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Budget
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
Public transit options for Praha-Holesovice
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
The major train station for arrivals in Brussels is Bruxelles-Midi. Find all the information you need to know about services, amenities and connections at Bruxelles-Midi for your journey to Brussels from Prague.
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Ticket Office Hours
- Mon - Sun: 05:45 - 21:30
Wifi
- Wi-Fi is available for a fee.
Lockers
- Baggage storage facility is located across from the Thalys business lounge.
Dining
- Pullman Hotel Bar
- Quick Gare du Midi
- Subway
- EXKi Zuid
- Starbucks
- Häagen-Dazs
- Sbarro
- The Coffee Club
- The Belgian Chocolate House
- PAUL
- & many more
Accessibility
- Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Hotel
- Les Lofts De Styliste
- Park Inn by Radisson Brussels Midi
- Pullman Brussels Centre Midi
Information Desk
- Located in the main concourse and next to the international platforms.
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Ticket Office Hours
- Mon - Sun: 06:15 - 22:00
Wifi
- Free Wi-Fi available in Starbucks.
Lockers
- Luggage lockers are located on Level 0 near Platforms 1 and 2.
Dining
- Starbucks
- Brasserie 28 Brewery
- Panos
- Delitraiteur Eat & Go
Accessibility
- Station has a wide range of facilities for passengers with limited mobility: elevators and escalators to platforms, wheelchair lifts and mobile ramps, barrier-free toilets and accessible parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Hotel
- Hilton Brussels Grand Palace
- Hotel NH Brussels Carrefour de l'Europe
- Hôtel The Moon
Ticket Office
- Mon - Sun: 06:15 - 22:00
Information Desk
- Travel Center / information desk is located on the left side from the main entrance.
Public transit options for Bruxelles-Central
- Metro lines: 1, 5
- Train lines: IC, Intercity Direct 9200, RER (S1, S2, S3, S6, S8, S10)
Bruxelles-Congres
Amenities at train station
ParkingDiningATMTaxisAccessibilityWCHotelBike ParkingBike Rentalinformation
More options for your journey from Prague to Brussels
Here are some other resources that might have the information you need
Most popular trains to and from Brussels and Prague
Most popular train connections to Brussels
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