The cheapest and fastest trains from Prague to Brussels
Cheapest price
$146
Average price
$231
Fastest journey
11 h 4 m
Average duration
11 h 4 m
Trains per day
11
Distance
717 km
The best way to find a cheap train ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Brussels will cost around $231 if you buy it on the day, but the cheapest tickets can be found for only $146.
It's difficult to get from Prague to Brussels without transferring at least 2 times.
rj 176 · ICE 554 · ICE 318
rj 382 · ICE 556 · ICE 10
rj 178 · ICE 558 · ICE 12
EX 352 · 3580 · ICE 522 · 26840
EX 352 · 3580 · ICE 522 · ICE 920
rj 176 · ICE 554 · ICE 318
rj 382 · ICE 556 · ICE 10
rj 178 · ICE 558 · ICE 12
RJ 176 · IC 2444 · ICE 693 · ICE 318
RJ 382 · IC 2442 · ICE 691 · ICE 10Travel Information
Compare train, bus, and flight for Prague to Brussels
Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €27. For those with little time consider booking a flight which can get you there in 2h 27m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €27, and a flight costs an average of €34.
Distance: 445 miles (717 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
€161 Average price | €192 Average price | €66 Average price Cheapest |
13h 42m Average total duration 13h 12m Onboard + 30m Additional time* | 5h 27m Average total duration Fastest 2h 27m Onboard + 3h 0m Additional time* | 14h 9m Average total duration 13h 39m Onboard + 30m Additional time* |
0.2 - 0.6kg CO2 emissions Lowest | 2.2 - 4.3kg CO2 emissions | 0.7 - 1.8kg CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Brussels train times
The table below shows live departures for Prague to Brussels trains for today, Friday, January 30. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:28 PM Prague | 18h07 | 1:35 PM Brussels | 0 transfersDirect | |
| Saturday, January 31 | |||||
rj 178 · ICE 558 · ICE 12 | On time 7:31 AM Prague hlavní nádraží | 11h04 | 6:35 PM Brussels-Midi | 2 transfers | |
RJ 178 · IC 2440 · ICE 599 · ICE 12 | On time 7:31 AM Prague hlavní nádraží | 11h04 | 6:35 PM Brussels-Midi | 3 transfers | |
EX 358 · ICE 26 · ICE 10 | On time 8:35 AM Prague hlavní nádraží | 12h00 | 8:35 PM Brussels-Midi | 2 transfers | |
rj 382 · ICE 556 · ICE 10 | 9:31 AM Prague hlavní nádraží | 11h04 | 8:35 PM Brussels-Midi | 2 transfers | |
RJ 382 · IC 2442 · ICE 691 · ICE 10 | On time 9:31 AM Prague hlavní nádraží | 11h04 | 8:35 PM Brussels-Midi | 3 transfers | |
EX 356 · ICE 24 · ICE 318 | 10:35 AM Prague hlavní nádraží | 12h00 | 10:35 PM Brussels-Midi | 2 transfers | |
rj 176 · ICE 554 · ICE 318 | 11:31 AM Prague hlavní nádraží | 11h04 | 10:35 PM Brussels-Midi | 2 transfers | |
RJ 176 · IC 2444 · ICE 693 · ICE 318 | On time 11:31 AM Prague hlavní nádraží | 11h04 | 10:35 PM Brussels-Midi | 3 transfers | |
EX 352 · 3580 · ICE 522 · 26840 | On time 2:35 PM Prague hlavní nádraží | 17h25 | 8:00 AM Brussels-Midi | 5 transfers | |
EX 352 · 3580 · ICE 522 · ICE 920 | On time 2:35 PM Prague hlavní nádraží | 17h25 | 8:00 AM Brussels-Midi | 6 transfers | |
EC 458 · EC 10458 · ICE 2508 · ICE 699 | On time 5:31 PM Prague hlavní nádraží | 15h04 | 8:35 AM Brussels-Midi | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 31
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Why should you book Prague to Brussels trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of European Sleeper or European Sleeper to find the best option for your trip from Prague to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Brussels.
Why book with Omio over Trainline or Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of European Sleeper or European Sleeper to find the best option for your trip from Prague to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Brussels.
How far in advance should I book train tickets from Prague to Brussels?
Journey information
Overview: Train from Prague to Brussels
Trains from Prague to Brussels run on average 5 times per day, taking around 13h 12m. Cheap train tickets for this journey start at $112 (€88) but you can travel from only $34 (€27) by bus.
The earliest train runs at 00:10, the last at 23:50. The fastest train covers the 445 miles (717 km) distance in 10h 55m.
Distance 445 miles (717 km) |
Average train duration 13h 12m |
Cheapest ticket price $112 (€88) |
Trains per day 5 |
Fastest train 10h 55m |
First train 00:10 |
Last train 23:50 |
Train companies: Deutsche Bahn, European Sleeper from Prague to Brussels trainsDeutsche Bahn, European Sleeper trains will get you between Prague and Brussels from $34 (€27). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
European Sleeper
FAQs: Trains from Prague to Brussels
Find answers to the most common questions about traveling from Prague to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Prague to Brussels
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
- Mon - Sun: 05:45 - 21:30
- Wi-Fi is available for a fee.
- Baggage storage facility is located across from the Thalys business lounge.
- Pullman Hotel Bar
- Quick Gare du Midi
- Subway
- EXKi Zuid
- Starbucks
- Häagen-Dazs
- Sbarro
- The Coffee Club
- The Belgian Chocolate House
- PAUL
- & many more
- Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Les Lofts De Styliste
- Park Inn by Radisson Brussels Midi
- Pullman Brussels Centre Midi
- Located in the main concourse and next to the international platforms.
- Mon - Sun: 06:15 - 22:00
- Free Wi-Fi available in Starbucks.
- Luggage lockers are located on Level 0 near Platforms 1 and 2.
- Starbucks
- Brasserie 28 Brewery
- Panos
- Delitraiteur Eat & Go
- Station has a wide range of facilities for passengers with limited mobility: elevators and escalators to platforms, wheelchair lifts and mobile ramps, barrier-free toilets and accessible parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Hilton Brussels Grand Palace
- Hotel NH Brussels Carrefour de l'Europe
- Hôtel The Moon
- Mon - Sun: 06:15 - 22:00
- Travel Center / information desk is located on the left side from the main entrance.
- Metro lines: 1, 5
- Train lines: IC, Intercity Direct 9200, RER (S1, S2, S3, S6, S8, S10)
More options for your journey from Prague to Brussels
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