Travel Information
Compare train and bus for Prague to Karlsruhe
Omio recommends booking the train as it is the most popular option from Prague to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from $33. For those with little time consider booking a bus which can get you there in 6h 43m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $33, and a train costs an average of $40.
Distance: 280 miles (452 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$106 Average price | $48 Average price Cheapest | $116 Average price (fuel + tolls) |
9h 29m Average total duration 8h 59m Onboard + 30m Additional time* | 7h 13m Average total duration Fastest 6h 43m Onboard + 30m Additional time* | 5h 2m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Karlsruhe:
A bus is $57 (€46) less than a train for this route with tickets for a train from Prague to Karlsruhe costing on average $106 (€86).
Other travel options to Karlsruhe take longer:
Train takes on average 8h 59m.
Travel optionsfrom Prague to Karlsruhe
How to get from Prague to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Prague to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBus6:40 AM8h35Praha, ÚAN Florenc3:15 PMKarlsruhe Hbf$591One-way0 transfers
Cheapest
FlixBus6:40 AM8h35Praha, ÚAN Florenc3:15 PMKarlsruhe Hbf$591One-way0 transfers
Fastest
DE4410+
ICE 919 · ICE 7312:00 PM3h23Prague Vaclav Havel Airport3:23 PMKarlsruhe Hbf$5831One-way2 transfers
Other options
EX 356 · 3574 · IC 206611:35 AM9h19Prague hlavní nádraží8:54 PMKarlsruhe Hbf$611One-way2 transfers
EX 356 · ICE 56011:35 AM10h17Prague hlavní nádraží9:52 PMKarlsruhe Hbf$681One-way1 transfer
EX 356 · 3572 · 88620 · ICE 26611:35 AM8h17Prague hlavní nádraží7:52 PMKarlsruhe Hbf$821One-way3 transfers
FlixBus10:25 PM8h10Praha, M. Horákové (Hradčanská)6:35 AMKarlsruhe Hbf$611One-way0 transfers
FlixBus10:00 PM8h35Praha, ÚAN Florenc6:35 AMKarlsruhe Hbf$611One-way0 transfers
FlixBus · FlixBus9:50 PM8h45Praha, Na Knížecí6:35 AMKarlsruhe Hbf$691One-way1 transfer
LH1393+
ICE 517 · ICE 3719:05 AM4h54Prague Vaclav Havel Airport1:59 PMKarlsruhe Hbf$2501One-way2 transfers
LH1393+
ICE 919 · ICE 739:05 AM6h18Prague Vaclav Havel Airport3:23 PMKarlsruhe Hbf$2501One-way2 transfers
LH1403+
ICE 513 · ICE 2776:00 AM3h59Prague Vaclav Havel Airport9:59 AMKarlsruhe Hbf$2621One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 25
May 26
May 27
May 28
May 29
May 30
May 31
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Prague to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Karlsruhe.

This is compared to other travel options from Prague to Karlsruhe:
A bus is $57 (€46) less than a train for this route with tickets for a train from Prague to Karlsruhe costing on average $106 (€86).
Other travel options to Karlsruhe take longer:
Train takes on average 8h 59m.
- Around 20 buses per day.
- Around 10 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Prague hlavní nádraží and arrive in Karlsruhe Hbf.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Karlsruhe Hbf.
- Travel with FlixBus, BlaBlaCar, Infobus to go to Karlsruhe by bus.
- Travel with Deutsche Bahn, České dráhy, ÖBB | Euro City (EC) to go to Karlsruhe by train.
- 8 direct buses per day with FlixBus, BlaBlaCar, Infobus.
- 0 direct trains per day with ÖBB | Euro City (EC).
Travelling from Prague to Karlsruhe: related information
Here are some other resources that might have the information you need
