Travel Information
Compare train and bus for Prague to Karlsruhe
Omio recommends booking the train as it is the most popular option from Prague to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a bus which can get you there in 6h 43m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $32, and a train costs an average of $40.
Distance: 280 miles (452 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$104 Average price | $48 Average price Cheapest | $114 Average price (fuel + tolls) |
9h 29m Average total duration 8h 59m Onboard + 30m Additional time* | 7h 13m Average total duration Fastest 6h 43m Onboard + 30m Additional time* | 5h 2m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Karlsruhe:
A bus is $56 (€46) less than a train for this route with tickets for a train from Prague to Karlsruhe costing on average $104 (€86).
Other travel options to Karlsruhe take longer:
Train takes on average 8h 59m.
Travel optionsfrom Prague to Karlsruhe
How to get from Prague to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Prague to Karlsruhe is by taking a train because it’s the best combination of price and speed.
EX 354 · 3578 · IC 20641:35 PM9h19Prague hlavní nádraží10:54 PMKarlsruhe Hbf$401One-way2 transfers
Cheapest
EX 354 · 3578 · IC 20641:35 PM9h19Prague hlavní nádraží10:54 PMKarlsruhe Hbf$401One-way2 transfers
Fastest
DE4410+
ICE 919 · ICE 7312:10 PM3h13Prague Vaclav Havel Airport3:23 PMKarlsruhe Hbf$2221One-way2 transfers
Other options
EX 352 · ICE 1060 · 190363:35 PM9h44Prague hlavní nádraží1:19 AMKarlsruhe Hbf$461One-way2 transfers
EX 356 · 3574 · IC 206611:35 AM9h19Prague hlavní nádraží8:54 PMKarlsruhe Hbf$661One-way2 transfers
EX 354 · 3433 · ICE 1163 · ICE 5601:35 PM8h17Prague hlavní nádraží9:52 PMKarlsruhe Hbf$721One-way3 transfers
FlixBus10:25 PM8h10Praha, M. Horákové (Hradčanská)6:35 AMKarlsruhe Hbf$551One-way0 transfers
FlixBus10:00 PM8h35Praha, ÚAN Florenc6:35 AMKarlsruhe Hbf$551One-way0 transfers
FlixBus3:10 PM8h40Praha, ÚAN Florenc11:50 PMKarlsruhe Hbf$551One-way0 transfers
LH1401+
ICE 2056:25 PM4h34Prague Vaclav Havel Airport10:59 PMKarlsruhe Hbf$1331One-way1 transfer
LH1401+
ICE 615 · ICE 3796:25 PM3h34Prague Vaclav Havel Airport9:59 PMKarlsruhe Hbf$1361One-way2 transfers
LH1397+
ICE 2052:30 PM8h29Prague Vaclav Havel Airport10:59 PMKarlsruhe Hbf$1541One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Prague to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Karlsruhe.

This is compared to other travel options from Prague to Karlsruhe:
A bus is $56 (€46) less than a train for this route with tickets for a train from Prague to Karlsruhe costing on average $104 (€86).
Other travel options to Karlsruhe take longer:
Train takes on average 8h 59m.
- Around 20 buses per day.
- Around 10 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Karlsruhe Hbf.
- Trains mostly depart from Prague hlavní nádraží and arrive in Karlsruhe Hbf.
- Travel with FlixBus, BlaBlaCar, Infobus to go to Karlsruhe by bus.
- Travel with Deutsche Bahn, České dráhy, ÖBB | Euro City (EC) to go to Karlsruhe by train.
- 8 direct buses per day with FlixBus, BlaBlaCar, Infobus.
- 0 direct trains per day with ÖBB | Euro City (EC).
Travelling from Prague to Karlsruhe: related information
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