Travel Information
Compare train and bus for Prague to Karlsruhe
Omio recommends booking the train as it is the most popular option from Prague to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from €25. For those with little time consider booking a bus which can get you there in 7h 6m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €25, and a train costs an average of €28.
Distance: 280 miles (452 km)
Compare train with
Most popular Train | Bus |
|---|---|
€72 Average price | €37 Average price Cheapest |
10h 13m Average total duration 9h 43m Onboard + 30m Additional time* | 7h 36m Average total duration Fastest 7h 6m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.1kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Prague to Karlsruhe
How to get from Prague to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Prague to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
FlixBusFastest
DE4408+
ICE 915 · ICE 71Other options
EX 358 · 3568 · 88618 · ICE 1064
EX 358 · 3570 · IC 2068
EX 358 · ICE 266
FlixBus
FlixBus
FlixBus
DE4406+
ICE 203
DE4406+
ICE 205
DE4406+
ICE 615 · ICE 379Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Prague to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Karlsruhe.

There are 2 ways to get from Prague to Karlsruhe: train or bus.
The cheapest way to travel to Karlsruhe from Prague is a train with an average price of $23 (€21).
This is compared to other travel options from Prague to Karlsruhe:
Taking a train costs $6 (€5) less than taking a bus, which average ticket prices of $29 (€26).
Taking a train costs () less than taking a flight, which costs on average () for the same trip.
The fastest way to get to Karlsruhe from Prague is by bus with an average travel time of 8 h 5 min.
Other travel options to Karlsruhe take longer:
Getting to Karlsruhe by train takes 8 h 17 min on average.
The distance from Prague to Karlsruhe is approximately 280 miles (451 km).
The average frequency per day from Prague to Karlsruhe is:
- Around 19 buses per day.
- 51 flights per day.
- 8 trains a day.
However, we recommend checking specific travel dates for your route to Karlsruhe from Prague as scheduled services by train or bus can vary by season or day of the week.
These are the most popular departure and arrival points when traveling from Prague to Karlsruhe:
- Most travelers board their bus from Prague, Central Train Station and arrive in Karlsruhe Hbf.
- Most travelers who buy a train ticket from Prague to Karlsruhe depart from Prague hlavní nádraží to Karlsruhe Hbf.
The following travel companies offer services from Prague to Karlsruhe:
- Travel with FlixBus to go to Karlsruhe by bus. For a good deal on tickets, you can find FlixBus Prague to Karlsruhe tickets on Omio for $29 (€26).
- Travel with Deutsche Bahn or ÖBB | Euro City (EC) to go to Karlsruhe by train. For a good deal on tickets, you can find Deutsche Bahn Prague to Karlsruhe tickets on Omio for $23 (€21).
Yes, there are direct services available from Prague to Karlsruhe with the following travel companies:
- 7 direct buses per day with FlixBus.
Direct services tend to save you time and add more convenience in getting you to Karlsruhe as you won't need to transfer at another stop in between, so it's worth paying attention to before booking your tickets to Karlsruhe from Prague.
Travelling from Prague to Karlsruhe: related information
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