Travel Information
Compare train and bus for Prague to Karlsruhe
Omio recommends booking the train as it is the most popular option from Prague to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from kr203. For those with little time consider booking a bus which can get you there in 6h 41m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of kr203, and a train costs an average of kr276.
Distance: 280 miles (452 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
kr585 Average price | kr305 Average price Cheapest | kr755 Average price (fuel + tolls) |
9h 35m Average total duration 9h 5m Onboard + 30m Additional time* | 7h 11m Average total duration Fastest 6h 41m Onboard + 30m Additional time* | 5h 2m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Karlsruhe:
A bus is kr280 less than a train for this route with tickets for a train from Prague to Karlsruhe costing on average kr585.
Other travel options to Karlsruhe take longer:
Train takes on average 9h 5m.
Travel optionsfrom Prague to Karlsruhe
How to get from Prague to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Prague to Karlsruhe is by taking a train because it’s the best combination of price and speed.
EX 354 · 3578 · IC 20641:35 PM9h19Prague hlavní nádraží10:54 PMKarlsruhe Hbfkr2311One-way2 transfers
Cheapest
EX 354 · 3578 · IC 20641:35 PM9h19Prague hlavní nádraží10:54 PMKarlsruhe Hbfkr2311One-way2 transfers
Fastest
FlixBus10:25 PM8h10Praha, M. Horákové (Hradčanská)6:35 AMKarlsruhe Hbfkr3341One-way0 transfers
Other options
EX 354 · 3578 · IC 20641:35 PM9h19Prague hlavní nádraží10:54 PMKarlsruhekr2871One-way2 transfers
EC 458 · ICE 699 · IC 604036:31 PM9h29Prague hlavní nádraží4:00 AMKarlsruhe Hbfkr3101One-way2 transfers
R 676 · Os 28015 · S1 · 165386:47 PM14h06Prague hlavní nádraží8:53 AMKarlsruhe Hbfkr3101One-way5 transfers
FlixBus3:10 PM8h40Praha, ÚAN Florenc11:50 PMKarlsruhe Hbfkr3261One-way0 transfers
FlixBus2:30 PM9h20Praha, Černý Most11:50 PMKarlsruhe Hbfkr3261One-way0 transfers
FlixBus10:00 PM8h35Praha, ÚAN Florenc6:35 AMKarlsruhe Hbfkr3341One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Prague to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Karlsruhe.

This is compared to other travel options from Prague to Karlsruhe:
A bus is kr280 less than a train for this route with tickets for a train from Prague to Karlsruhe costing on average kr585.
Other travel options to Karlsruhe take longer:
Train takes on average 9h 5m.
- Around 19 buses per day.
- Around 10 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Prague hlavní nádraží and arrive in Karlsruhe Hbf.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Karlsruhe Hbf.
- Travel with Deutsche Bahn, České dráhy, ÖBB | Euro City (EC) to go to Karlsruhe by train.
- Travel with FlixBus, BlaBlaCar, Infobus to go to Karlsruhe by bus.
- 0 direct trains per day with ÖBB | Euro City (EC).
- 8 direct buses per day with FlixBus, BlaBlaCar, Infobus.
Travelling from Prague to Karlsruhe: related information
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