- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price on Sep 05
$44
Average ticket price on Sep 05
$117
Fastest journey on Sep 05
8 h 16 m
Average journey duration on Sep 05
8 h 27 m
Trains on Sep 05
15
Distance
452 km
The best way to find a cheap train ticket from Karlsruhe to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Prague will cost around $117 if you buy it on the day, but the cheapest tickets can be found for only $44.
It's difficult to get from Karlsruhe to Prague without transferring at least 3 times.
FlixTrain+
FlixBus
S6 · ICE 699+
355
IC 60402 · ICE 619+
353
TGV 9593+
ICE 517+
363
ICE 204 · ICE 511+
357
ICE 200 · ICE 690 · IC 2441 · RJ 177
ICE 204 · ICE 694 · IC 2445 · RJ 175
ICE 202 · ICE 692 · IC 2443 · RJ 383
ICE 108 · ICE 598 · IC 2049 · RJ 385
19009 · 88617 · 3569+
359Omio recommends booking the train as it is the most popular option from Karlsruhe to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $58 For those with little time, consider booking a train, which has an average total journey time of 8h 36m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $58, while a train costs an average of $151.
Distance: 280 miles (452 km)
Most popular Train | Bus | Driving |
|---|---|---|
$151 Average price | $58 Average price Cheapest | $117 Average price (fuel + tolls) |
8h 36m Average total duration Fastest 8h 6m Onboard + 30m Additional time* | 9h 16m Average total duration 8h 46m Onboard + 30m Additional time* | 5h 45m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Prague:
A bus is $93 less than a train for this route with tickets for a train from Karlsruhe to Prague costing on average $151.
Other travel options to Prague take longer:
Bus takes on average 8h 46m.
Tickets start at around $151 compared to roughly $117 in fuel and tolls — a saving of about $-34.16. The journey takes 8h 6m versus 5h 45m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Karlsruhe to Prague trains for tomorrow, Saturday, September 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
S6 · ICE 618 · ICE 696 · IC 2447 | On time 2:13 AM Karlsruhe | 11h12 | 1:25 PM Prague hlavní nádraží | 4 transfers | |
S6 · ICE 699+ 355 | 2:13 AM Karlsruhe | 12h08 | 2:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 204 · ICE 694 · IC 2445 · RJ 175 | On time 6:59 AM Karlsruhe | 8h16 | 3:15 PM Prague-Holešovice | 3 transfers | |
ICE 204 · ICE 511+ 357 | On time 6:59 AM Karlsruhe | 9h22 | 4:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 202 · ICE 692 · IC 2443 · RJ 383 | On time 8:59 AM Karlsruhe | 8h26 | 5:25 PM Prague hlavní nádraží | 3 transfers | |
ICE 9585 · ICE 513+ 359 | Delayed 7:42 AM 9:28 AMKarlsruhe | 8h53 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
19009 · 88617 · 3569+ 359 | 9:32 AM Karlsruhe | 8h49 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
FlixTrain+ FlixBus | 10:26 AM Karlsruhe Hbf | 11h14 | 9:40 PM Praha, ÚAN Florenc | 1 transfer | |
ICE 200 · ICE 690 · IC 2441 · RJ 177 | On time 10:59 AM Karlsruhe | 8h16 | 7:15 PM Prague-Holešovice | 3 transfers | |
ICE 200 · ICE 515+ 361 | On time 10:59 AM Karlsruhe | 9h22 | 8:21 PM Prague hlavní nádraží | 2 transfers | |
19013 · 88619 · 3573+ 361 | 11:32 AM Karlsruhe | 8h49 | 8:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 108 · ICE 598 · IC 2049 · RJ 385 | On time 12:59 PM Karlsruhe | 8h26 | 9:25 PM Prague hlavní nádraží | 3 transfers | |
ICE 517+ TGV 9593+ 363 | Delayed 12:17 PM 1:27 PMKarlsruhe | 8h55 | 10:22 PM Prague hlavní nádraží | 2 transfers | |
19017 · 88621 · 3577+ 363 | 1:32 PM Karlsruhe | 8h50 | 10:22 PM Prague hlavní nádraží | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Karlsruhe to Prague run on average 10 times per day, taking around 8h 6m. Cheap train tickets for this journey start at $12 if you book in advance.
The earliest train runs at 00:19, the last at 23:51. The fastest train covers the 280 miles (452 km) distance in 7h 18m.
Distance 280 miles (452 km) |
Average train duration 8h 6m |
Cheapest ticket price $12 |
Trains per day 10 |
Fastest train 7h 18m |
First train 12:19 AM |
Last train 11:51 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sat |
Best time to book 42 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Praha hlavní nádraží -> Václavské náměstí, Prague
Find answers to the most common questions about traveling from Karlsruhe to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Karlsruhe to Prague trains use the Karlsruhe Hbf to Praha hlavní nádraží station pair, with some services arriving at Praha-Holesovice. Use this guide to compare Karlsruhe and Prague train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Karlsruhe Hbf is 1 km from Karlsruhe city centre. Public transport options include:
Karlsruhe Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Vinarte, Am Tiergarten, Panorama, Alter Brauhof
Wi-Fi is available at Karlsruhe Hbf. ATMs are available at Karlsruhe Hbf.
Ticket office support is available at Karlsruhe Hbf. Information desks are available at Karlsruhe Hbf.
Luggage storage is available at Karlsruhe Hbf. Lost and found is available at the station.
Available at Karlsruhe Hbf: Parking, Taxis, WC.
Available at Karlsruhe Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Karlsruhe Hbf.
Nearby hotels include Hotel Barbarossa, Hotel Avisa, Am Tiergarten, Aparthotel Aijana.
Karlsruhe-Durlach is 5 km from Karlsruhe city centre. Public transport options include:
Karlsruhe-Durlach has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Hubraum, Vogel Hausbräu Durlach, Asia Gourmet, Borsalino
Wi-Fi is available at Karlsruhe-Durlach. ATMs are available at Karlsruhe-Durlach.
Ticket office support is available at Karlsruhe-Durlach. Information desks are available at Karlsruhe-Durlach.
Luggage storage is available at Karlsruhe-Durlach. Lost and found is available at the station.
Available at Karlsruhe-Durlach: Parking, Taxis, WC.
Available at Karlsruhe-Durlach: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Karlsruhe-Durlach.
Nearby hotels include Hotel Große Linde, Zum Erwin, Der Blaue Reiter.
Karlsruhe-Mühlburg is 2 km from Karlsruhe city centre. Public transport options include:
Karlsruhe-Mühlburg has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Beim Schupi, McDonald's, Oberer See, Rhein Wok - Chinaimbiss
Wi-Fi is available at Karlsruhe-Mühlburg. ATMs are available at Karlsruhe-Mühlburg.
Ticket office support is available at Karlsruhe-Mühlburg. Information desks are available at Karlsruhe-Mühlburg.
Luggage storage is available at Karlsruhe-Mühlburg. Lost and found is available at the station.
Available at Karlsruhe-Mühlburg: Parking, Taxis, WC.
Available at Karlsruhe-Mühlburg: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Karlsruhe-Mühlburg.
Nearby hotels include Beim Schupi.
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Na Kovárně, Cross Club
Free. ATMs are available in the train station.
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Available at Praha-Holesovice: Parking, Taxis, WC.
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Kotleta, Café Imperial
Free. ATMs are available in the train station.
Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.
Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.
Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.
Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.
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