- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price on Oct 22
$59
Average ticket price on Oct 22
$174
Fastest journey on Oct 22
8 h 16 m
Average journey duration on Oct 22
8 h 33 m
Trains on Oct 22
23
Distance
452 km
The best way to find a cheap train ticket from Karlsruhe to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Prague will cost around $174 if you buy it on the day, but the cheapest tickets can be found for only $59.
On Thu, Oct 22, we found 23 trains from Karlsruhe to Prague, including 1 direct services.
On Thu, Oct 22 the direct trains cover the 452 km distance in an average of 8 h 33 m but if you time it right, some trains will get you there in just 8 h 16 m .
On Thu, Oct 22 the slowest trains will take 8 h 49 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixTrain+
FlixBus
ICE 376 · RJ 383
ICE 376 · RJ 383
EC 459
S1 · EC 459
ICE 267 · R 89685 · R 3565 · EC 60357
ICE 202 · ICE 692 · IC 2443 · rj 383
STR 3 · ICE 200 · ICE 690 · IC 2441
STR 3 · ICE 202 · ICE 692 · IC 2443
R 19009 · R 88617 · R 3569 · EC 60359Trains from Karlsruhe to Prague run on average 10 times per day, taking around 8h 5m. Cheap train tickets for this journey start at $9 (€7) if you book in advance.
The earliest train runs at 00:19, the last at 23:51. The fastest train covers the 280 miles (452 km) distance in 7h 18m.
Distance 280 miles (452 km) |
Average train duration 8h 5m |
Cheapest ticket price $9 (€7) |
Trains per day 10 |
Fastest train 7h 18m |
First train 12:19 AM |
Last train 11:51 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sat |
Best time to book 42 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Karlsruhe to Prague.
The table below shows live departures for Karlsruhe to Prague trains for tomorrow, Thursday, October 22. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
ICE 376 · RJ 383 | On time 7:59 AM Karlsruhe | 9h26 | 5:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 376 · RJ 383 | On time 7:59 AM Karlsruhe Hbf | 9h26 | 5:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 267 · R 89685 · R 3565 · EC 60357 | On time 8:05 AM Karlsruhe Hbf | 8h16 | 4:21 PM Prague hlavní nádraží | 4 transfers | |
ICE 267 · 89685 · 3565 · Bus RE25 | On time 8:05 AM Karlsruhe Hbf | 12h16 | 8:21 PM Prague hlavní nádraží | 4 transfers | |
ICE 267 · 89685 · 3567 · Bus RE25 | On time 8:05 AM Karlsruhe Hbf | 10h16 | 6:21 PM Prague hlavní nádraží | 4 transfers | |
ICE 267 · 89685 · 3565 · Bus RE25 | On time 8:05 AM Karlsruhe Hbf | 10h16 | 6:21 PM Prague hlavní nádraží | 4 transfers | |
ECE 8 · ICE 529 · 3567 · Bus RE25 | On time 8:37 AM Karlsruhe Hbf | 9h44 | 6:21 PM Prague hlavní nádraží | 4 transfers | |
ECE 8 · ICE 529 · 3567 · Bus RE25 | On time 8:37 AM Karlsruhe Hbf | 11h44 | 8:21 PM Prague hlavní nádraží | 4 transfers | |
STR 3 · ICE 202 · ICE 692 · IC 2443 | On time 8:44 AM Europaplatz/Post Galerie (Karlstraße) | 8h41 | 5:25 PM Prague hlavní nádraží | 4 transfers | |
ICE 202 · ICE 692 · IC 2443 · rj 383 | On time 8:59 AM Karlsruhe Hbf | 8h26 | 5:25 PM Prague hlavní nádraží | 3 transfers | |
IC 2067 · 3567 · Bus RE25 · EX 359 | On time 9:06 AM Karlsruhe Hbf | 9h15 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
IC 2067 · R 3567 · EC 61359 · EC 359 | On time 9:06 AM Karlsruhe Hbf | 9h15 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
IC 2067 · 3567 · Bus RE25 · EX 361 | On time 9:06 AM Karlsruhe Hbf | 11h15 | 8:21 PM Prague hlavní nádraží | 3 transfers | |
STR 1 · 19009 · 88617 · 3569 | 9:21 AM Europaplatz/Post Galerie (Karlstraße) | 9h00 | 6:21 PM Prague hlavní nádraží | 5 transfers | |
R 19009 · R 88617 · R 3569 · EC 60359 | 9:32 AM Karlsruhe Hbf | 8h49 | 6:21 PM Prague hlavní nádraží | 4 transfers | |
STR 3 · ICE 374 · ICE 1559 · S1 | 9:44 AM Europaplatz/Post Galerie (Karlstraße) | 9h26 | 7:10 PM Prague hlavní nádraží | 5 transfers | |
STR 3 · ICE 374 · ICE 1559 · RJ 177 | On time 9:44 AM Europaplatz/Post Galerie (Karlstraße) | 9h31 | 7:15 PM Prague-Holešovice | 3 transfers | |
ICE 374 · ICE 1559 · S 31747 · Os 28010 | On time 9:59 AM Karlsruhe Hbf | 9h11 | 7:10 PM Prague hlavní nádraží | 4 transfers | |
STR 3 · IC 2069 · 3571 · Bus RE25 | 10:44 AM Europaplatz/Post Galerie (Karlstraße) | 9h37 | 8:21 PM Prague hlavní nádraží | 4 transfers | |
STR 3 · ICE 200 · ICE 690 · IC 2441 | On time 10:44 AM Europaplatz/Post Galerie (Karlstraße) | 8h31 | 7:15 PM Prague-Holešovice | 4 transfers | |
FlixTrain+ FlixBus | 2:23 PM Karlsruhe Hbf | 11h17 | 1:40 AM Prague, Central Train Station | 1 transfer | |
S1 · EC 459 | On time 10:43 PM Europaplatz/Post Galerie (Karlstraße) | 10h42 | 9:25 AM Prague hlavní nádraží | 1 transfer | |
EC 459 | On time 11:09 PM Karlsruhe Hbf | 10h16 | 9:25 AM Prague hlavní nádraží | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Praha hlavní nádraží -> Václavské náměstí, Prague
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Prague.
Find answers to the most common questions about traveling from Karlsruhe to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Karlsruhe to Prague trains use the Karlsruhe Hbf to Praha hlavní nádraží station pair, with some services arriving at Praha-Holesovice. Use this guide to compare Karlsruhe and Prague train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Karlsruhe Hbf is 1 km from Karlsruhe city centre. Public transport options include:
Karlsruhe Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Vinarte, Am Tiergarten, Panorama, Alter Brauhof
Wi-Fi is available at Karlsruhe Hbf. ATMs are available at Karlsruhe Hbf.
Ticket office support is available at Karlsruhe Hbf. Information desks are available at Karlsruhe Hbf.
Luggage storage is available at Karlsruhe Hbf. Lost and found is available at the station.
Available at Karlsruhe Hbf: Parking, Taxis, WC.
Available at Karlsruhe Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Karlsruhe Hbf.
Nearby hotels include Hotel Barbarossa, Hotel Avisa, Am Tiergarten, Aparthotel Aijana.
Karlsruhe-Mühlburg is 2 km from Karlsruhe city centre. Public transport options include:
Karlsruhe-Mühlburg has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Beim Schupi, McDonald's, Oberer See, Rhein Wok - Chinaimbiss
Wi-Fi is available at Karlsruhe-Mühlburg. ATMs are available at Karlsruhe-Mühlburg.
Ticket office support is available at Karlsruhe-Mühlburg. Information desks are available at Karlsruhe-Mühlburg.
Luggage storage is available at Karlsruhe-Mühlburg. Lost and found is available at the station.
Available at Karlsruhe-Mühlburg: Parking, Taxis, WC.
Available at Karlsruhe-Mühlburg: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Karlsruhe-Mühlburg.
Nearby hotels include Beim Schupi.
Europaplatz/Post Galerie (Karlstraße) has practical services for this route, including Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Bike Parking, Bike Rental, and Car Rental.
Food and drink options are available at Europaplatz/Post Galerie (Karlstraße).
ATMs are available at Europaplatz/Post Galerie (Karlstraße).
Available at Europaplatz/Post Galerie (Karlstraße): Parking, Taxis, WC.
Available at Europaplatz/Post Galerie (Karlstraße): Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Europaplatz/Post Galerie (Karlstraße).
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Na Kovárně, Cross Club
Free. ATMs are available in the train station.
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Available at Praha-Holesovice: Parking, Taxis, WC.
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Praha-Smichov is 3 km from Prague city centre. Public transport options include:
Praha-Smichov has practical services for this route, including Parking, Dining, ATM, Accessibility, WC, Hotel, Bike Parking, and Bike Rental.
Food and drink options are available at Praha-Smichov.
ATMs are available at Praha-Smichov.
Available at Praha-Smichov: Parking, WC.
Available at Praha-Smichov: Bike Parking, Bike Rental.
Accessibility facilities are available at Praha-Smichov.
Check train stations information for Karlsruhe and Prague, including where trains depart and arrive on this route.
Here are some other resources that might have the information you need