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Karlsruhe to Prague train with Deutsche Bahn (RE,IC,EC,ICE)

Sat, Jan 17
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Deutsche Bahn
Alex
Regionale
iryo
Italo
1,000+ travel companies
Deutsche Bahn
Alex
Regionale
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Italo
1,000+ travel companies
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The cheapest and fastest trains from Karlsruhe to Prague

Showing times and prices for Jan 19

Cheapest price

$37

Average price

$145

Fastest journey

8 h 16 m

Average duration

8 h 27 m

Trains per day

18

Distance

452 km

Cheap tickets

The best way to find a cheap train ticket from Karlsruhe to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Karlsruhe to Prague will cost around $145 if you buy it on the day, but the cheapest tickets can be found for only $37.

Fast trains

It's difficult to get from Karlsruhe to Prague without transferring at least 3 times.

FlixTrainFlixTrain+FlixBusFlixBus
02:23PM11h17
Karlsruhe Hbf
01:40AMPrague, Central Train Station
$371One-way
1 transfer
FlixTrainFlixTrain+FlixBusFlixBus
10:26AM11h14
Karlsruhe Hbf
09:40PMPraha, ÚAN Florenc
$371One-way
1 transfer
Deutsche BahnIC 2067 · 3569+Alex359
09:06AM9h15
Karlsruhe Hbf
06:21PMPrague hlavní nádraží
$721One-way
2 transfers
České dráhyICE 202 · ICE 692 · IC 2443 · rj 383
08:59AM8h26
Karlsruhe Hbf
05:25PMPrague hlavní nádraží
$891One-way
3 transfers
Deutsche BahnICE 376 · ICE 1557 · RJ 383
07:59AM9h26
Karlsruhe Hbf
05:25PMPrague hlavní nádraží
$931One-way
2 transfers

Travel Information

Compare bus and train for Karlsruhe to Prague

Omio recommends booking the train as it is the most popular option from Karlsruhe to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €26. For those with little time consider booking a bus which can get you there in 7h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €26, and a train costs an average of €28.

Distance: 280 miles (452 km)

Compare train with

Most popular
Train
Bus

€79

Average price

€43

Average price

Cheapest

9h 25m

Average total duration

8h 55m

Onboard

+

30m

Additional time*

7h 49m

Average total duration

Fastest

7h 19m

Onboard

+

30m

Additional time*

0.1 - 0.4kg

CO2 emissions

Lowest

0.5 - 1.1kg

CO2 emissions

Deutsche Bahn

Most popular train company

FlixBus

Most popular bus company

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

Karlsruhe to Prague train times

The table below shows live departures for Karlsruhe to Prague trains for today, Sunday, January 18. You can also manually refresh the results below to see updated train journeys.

Last updated at 12:22 AM
ProviderDepartsDurationArrivesTransfers
Tickets
deutsche_bahn6:51 AM Karlsruhe
8h31
3:22 PM Prague0 transfersDirect
deutsche_bahn7:06 AM Karlsruhe
9h16
4:22 PM Prague0 transfersDirect
deutsche_bahn7:28 AM Karlsruhe
8h54
4:22 PM Prague0 transfersDirect
deutsche_bahn9:05 AM Karlsruhe
8h17
5:22 PM Prague0 transfersDirect
deutsche_bahn9:32 AM Karlsruhe
8h50
6:22 PM Prague0 transfersDirect

Find all the dates and times for this journey

Compare prices and tickets Karlsruhe to Prague by bus or train

Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Jan 19
Tue
Jan 20
Wed
Jan 21
Thu
Jan 22
Fri
Jan 23
Sat
Jan 24
Sun
Jan 25

Why should you book Karlsruhe to Prague trains with Omio?

Deutsche Bahn (RE,IC,EC,ICE) as well as Alex offer trains services from Karlsruhe to Prague. Omio is an official ticket reseller for all your travel options from Karlsruhe to Prague.

Why book with Omio vs Deutsche Bahn (RE,IC,EC,ICE)?

  • Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn (RE,IC,EC,ICE), but also compare tickets for the likes of Alex to find the best option for your trip from Karlsruhe to Prague.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Deutsche Bahn (RE,IC,EC,ICE) with all available travel options, which are bus and train to ensure you get the best deal for traveling from Karlsruhe to Prague.

Why book with Omio over Trainline and Rail Europe?

Multiple modes of transport
  • Multiple travel company options: While Deutsche Bahn (RE,IC,EC,ICE) tickets can be bought on Deutsche Bahn (RE,IC,EC,ICE)'s website or third party sellers, Omio allows you to compare with the likes of Alex to help you choose the right option for your journey from Karlsruhe to Prague.
  • Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Karlsruhe to Prague.

How far in advance should I book train tickets from Karlsruhe to Prague?

The best time to book your train from Karlsruhe to Prague is 63 days before departure. See how prices for trains change on the Karlsruhe to Prague route.
Prices are for one-way tickets for one passenger from Karlsruhe to Prague per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from Karlsruhe to Prague.

Journey information

Overview: Train from Karlsruhe to Prague

GermanyGermany
CzechiaCzechia
Train Ticket Prices
  • Budget Options: Train tickets from Karlsruhe to Prague start from as low as $35 (€28) if booked well in advance.
  • Standard Fares: Typically, trains cost $97 (€79) depending on the train type and class.
Journey Duration & Frequency
  • On average there are 8 daily trains from Karlsruhe to Prague with 0 direct service.
  • The fastest trains can take as little as 8h 16m but the average duration is 8h 55m
Train Operators
  • Travel from Karlsruhe to Prague with Deutsche Bahn and Alex
  • The most booked train company for this route on Omio is Deutsche Bahn.
Stations & Schedule
  • Most trains depart from Karlsruhe Hbf and arrive in Prague hlavní nádraží
  • First train typically departs at 12:19 AM and the last at 11:50 PM
Distance
280 miles (452 km)
Average train duration
8h 55m
Cheapest ticket price
$35 (€28)
Trains per day
8
Fastest train
8h 16m
First train
00:19
Last train
23:50
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $32 (€26)
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $32 (€26)

Train companies: Deutsche Bahn, Alex from Karlsruhe to Prague trainsDeutsche Bahn, Alex trains will get you between Karlsruhe and Prague from $32 (€26). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Deutsche Bahn

About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Duration
8h 16m
Cheapest Price
$35 (€28)
Deutsche Bahn frequency
4 a day
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone

Alex

About
agilis is a railway company operating regional trains based in Regensburg in Bavaria since 2010. It operates in the German state of Bavaria connecting cities like Ulm, Ingolstadt, Regensburg and Plattling. They offer single tickets and comfortable trains with some popular routes covering Ulm to Regensburg, Neumarkt to Passau and Ingolstadt to Plattling.
Luggage & cancellation policy
Alex frequency
4 a day
Luggage included
One piece of hand luggage and one larger piece included
Luggage storage
Overhead racks and designated luggage areas
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund for canceled services
Amenities on board the train
Wifi
Food sold onboard
Snack and beverage service available on some routes
Seat reservation
Seat reservations available for additional fee
Toilets
USB plugs
Accessibility
Wheelchair spaces available, assistance for boarding/alighting
Pets
Small pets in carriers travel free, larger dogs require ticket and muzzle
Quiet zone

FAQs: Trains from Karlsruhe to Prague

Find answers to the most common questions about traveling from Karlsruhe to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

FAQs
Train ticket prices from Karlsruhe to Prague can vary. The cheapest ticket starts at $35 (€28), while the average price is around $97 (€79).
The train from Karlsruhe to Prague takes 8h 16m and runs 8 per day.
The distance by train from Karlsruhe to Prague is 280 miles (452 km).
The first train from Karlsruhe to Prague leaves at 12:19 AM.
The last train from Karlsruhe to Prague leaves at 11:50 PM.
There is no direct train service currently available from Karlsruhe to Prague.
Unfortunately, there is no night train available from Karlsruhe to Prague.
The train station in Karlsruhe that goes to Prague is Karlsruhe Hbf, which connects to Prague hlavní nádraží.
The cheapest way to get from Karlsruhe to Prague is by bus, with a cost of around $32 (€26).
The train journey from Karlsruhe to Prague offers scenic views of the German countryside, including lush forests and charming villages, as well as picturesque landscapes along the Elbe River as you approach Prague.
A day trip from Karlsruhe to Prague is not feasible as the journey takes 8h 16m. However, there are 8 trains per day covering the 280 miles (452 km) route.
In Prague, you can enjoy panoramic views from Petrin Hill and visit attractions like the Petrin Tower and Mirror Maze. Experience the vibrant nightlife in Vinohrady with its trendy bars and cafes, or take a boat cruise on the Vltava River for unique views of the city's landmarks. Delve into Czech history at the National Museum, and enjoy a classical music concert in one of the city's historic venues. Must-see sights include Prague Castle, Charles Bridge, Old Town Square with the Astronomical Clock, St. Vitus Cathedral, and the historic Jewish Quarter.
To fully experience Prague, 3 to 4 days are recommended, allowing time to explore key attractions like Prague Castle, Charles Bridge, Old Town Square, and the Jewish Quarter, as well as enjoy local cuisine and culture.
Yes, you can take the train from Karlsruhe to Prague.

popular train stations

Popular train stations from Karlsruhe to Prague

Karlsruhe
Prague
The major train station for departures in Karlsruhe is Karlsruhe Hbf. Find all the information you need to know about services, amenities and connections at Karlsruhe Hbf for your trip from Karlsruhe to Prague.
Amenities at train station
WifiWifi
LockersLockers
ShoppingShopping
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
LoungeLounge
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
ticketOfficeHours
Ticket Office Hours
  • Monday: 06:30 - 21:00
  • Tuesday: 06:30 - 21:00
  • Wednesday: 06:30 - 21:00
  • Thursday: 06:30 - 21:00
  • Friday: 06:30 - 21:00
  • Saturday: 08:00 - 19:00
  • Sunday: 09:00 - 20:00
ticketOfficeHours
Distance to city center
1 km
Dining
Dining
  • Vinarte
  • Am Tiergarten
  • Panorama
  • Alter Brauhof
Hotel
Hotel
  • Hotel Barbarossa
  • Hotel Avisa
  • Am Tiergarten
  • Aparthotel Aijana
Amenities at train station
WifiWifi
LockersLockers
ShoppingShopping
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
LoungeLounge
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
ticketOfficeHours
Ticket Office Hours
  • Monday: 08:00 13:30 - 12:30 18:00
  • Tuesday: 08:00 13:30 - 12:30 18:00
  • Wednesday: 08:00 13:30 - 12:30 18:00
  • Thursday: 08:00 13:30 - 12:30 18:00
  • Friday: 08:00 13:30 - 12:30 18:00
  • Saturday: 09:00 - 13:00
ticketOfficeHours
Distance to city center
5 km
Dining
Dining
  • Hubraum
  • Vogel Hausbräu Durlach
  • Asia Gourmet
  • Borsalino
Hotel
Hotel
  • Hotel Große Linde
  • Zum Erwin
  • Der Blaue Reiter
Karlsruhe WestWifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
Amenities at train station
WifiWifi
LockersLockers
ShoppingShopping
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
LoungeLounge
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
ticketOfficeHours
Distance to city center
1 km
Dining
Dining
  • Beim Schupi
  • Rosenstüble 2.0
  • Saloniki
  • Rote Taube
Hotel
Hotel
  • Beim Schupi

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