- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price on Oct 30
$0
Average ticket price on Oct 30
$155
Fastest journey on Oct 30
14 h 59 m
Average journey duration on Oct 30
19 h 21 m
Trains on Oct 30
5
Distance
771 km
The best way to find a cheap train ticket from Pisa to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
It's difficult to get from Pisa to Prague without transferring at least 3 times.

| Find prices | ||||||||

| Find prices | ||||||||

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||

| Find prices | ||||||||

|
| ||||||||||||

|
| ||||||||||||

| Find prices | ||||||||

|
| ||||||||||||
Trains from Pisa to Prague run on average 21 times per day, taking around 14h 13m. Cheap train tickets for this journey start at $12 (€10) if you book in advance.
The earliest train runs at 01:05, the last at 17:40. The fastest train covers the 479 miles (771 km) distance in 13h 59m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Pisa to Prague.
The table below shows live departures for Pisa to Prague trains for today, Thursday, October 29. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:02 AM Pisa | 23h37 | 10:39 AM Prague | 4 transfers | |
![]() | 11:25 AM Pisa | 28h56 | 4:21 PM Prague | 3 transfers | |
![]() | 1:09 PM Pisa | 24h14 | 1:23 PM Prague | 4 transfers | |
| Friday, October 30 | |||||
![]() | 5:22 AM Pisa | 14h59 | 8:21 PM Prague | 3 transfers | |
![]() | 5:47 AM Pisa | 17h45 | 11:32 PM Prague | 4 transfers | |
![]() | 6:50 AM Pisa | 16h52 | 11:42 PM Prague | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Trains from Pisa to Prague with Deutsche Bahn. Night trains available on this route with Deutsche Bahn. High-speed trains available on this route with Deutsche Bahn. Regional trains available on this route with Deutsche Bahn. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Praha hlavní nádraží -> Václavské náměstí, Prague
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Prague.
Find answers to the most common questions about traveling from Pisa to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Pisa to Prague trains use the Pisa Centrale to Praha hlavní nádraží station pair. Use this guide to compare Pisa and Prague train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Pisa Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, and Information Desk.
Food options include: McDonald's, Panetteria Binario 1
There is free Wi-Fi available at the McDonald's.
The ticket office is open Mon - Sun: 06:00 - 20:30. Information desks are located just outside the station on Piazza Vittorio Emanuele II.
Luggage storage is there is a luggage storage office near the end of Platform 1.
Available at Pisa Centrale: Parking, Taxis, WC.
Available at Pisa Centrale: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa Centrale: Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Nearby hotels include Hotel NH Pisa, Hotel La Pace, Hotel Maria.
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Check train stations information for Pisa and Prague, including where trains depart and arrive on this route.