- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price
$0.00
Average price
$147
Fastest journey
14 h 59 m
Average duration
21 h 15 m
Trains per day
5
Distance
771 km
The best way to find a cheap train ticket from Pisa to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
It's difficult to get from Pisa to Prague without transferring at least 3 times.










Trains from Pisa to Prague run on average 4 times per day, taking around 20h 3m. Cheap train tickets for this journey start at $241 (€196) but you can travel from only $28 (€23) by flight.
The earliest train runs at 01:05, the last at 17:40. The fastest train covers the 479 miles (771 km) distance in 14h 59m.
Distance 479 miles (771 km) |
Average train duration 20h 3m |
Cheapest ticket price $241 (€196) |
Trains per day 4 |
Fastest train 14h 59m |
First train 1:05 AM |
Last train 5:40 PM |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Wed |
Least Busy Day Sat |
The table below shows live departures for Pisa to Prague trains for today, Friday, July 31. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:22 AM Pisa | 14h59 | 8:21 PM Prague | 3 transfers | |
![]() | 5:47 AM Pisa | 17h45 | 11:32 PM Prague | 4 transfers | |
![]() | 6:50 AM Pisa | 16h52 | 11:42 PM Prague | 4 transfers | |
![]() | 11:25 AM Pisa | 22h56 | 10:21 AM Prague | 3 transfers | |
![]() | 1:09 PM Pisa | 24h14 | 1:23 PM Prague | 4 transfers |
Find all the dates and times for this journey
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Praha hlavní nádraží -> Václavské náměstí, Prague
Find answers to the most common questions about traveling from Pisa to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

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