- Must visit
National Museum
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
Cheapest price
$0.00
Average price
$188
Fastest journey
14 h 59 m
Average duration
16 h 32 m
Trains per day
3
Distance
771 km
The best way to find a cheap train ticket from Pisa to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
It's difficult to get from Pisa to Prague without transferring at least 3 times.






Omio recommends booking the flight as it is the most popular option from Pisa to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $63. For those with little time consider booking a flight which can get you there in 1h 52m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.8 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of $63, and a train costs an average of $242.
Distance: 479 miles (771 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$262 Average price | $216 Average price | $95 Average price Cheapest | $289 Average price (fuel + tolls) |
20h 33m Average total duration 20h 3m Onboard + 30m Additional time* | 4h 52m Average total duration Fastest 1h 52m Onboard + 3h 0m Additional time* | 17h 16m Average total duration 16h 46m Onboard + 30m Additional time* | 11h 54m Average total duration (door-to-door) |
- CO2 emissions | 2.3 - 4.6kg CO2 emissions | 0.8 - 1.9kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Prague:
A bus is $121 (€97) less than a flight for this route with tickets for a flight from Pisa to Prague costing on average $216 (€175).
A bus is $167 (€135) less than a train for this route with tickets for a train from Pisa to Prague costing on average $262 (€212).
Other travel options to Prague take longer:
Bus takes on average 16h 46m.
Train takes on average 20h 3m.
Tickets start at around $262 (€212) compared to roughly $289 (€234) in fuel and tolls — a saving of about $26 (€21). The journey takes 20h 3m versus 11h 54m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Pisa to Prague trains for tomorrow, Tuesday, June 16. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:22 AM Pisa | 14h59 | 8:21 PM Prague | 3 transfers | |
![]() | 5:47 AM Pisa | 17h45 | 11:32 PM Prague | 4 transfers | |
![]() | 6:50 AM Pisa | 16h52 | 11:42 PM Prague | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Pisa to Prague run on average 4 times per day, taking around 20h 3m. Cheap train tickets for this journey start at $242 (€196) but you can travel from only $28 (€23) by flight.
The earliest train runs at 01:05, the last at 17:40. The fastest train covers the 479 miles (771 km) distance in 14h 59m.
Distance 479 miles (771 km) |
Average train duration 20h 3m |
Cheapest ticket price $242 (€196) |
Trains per day 4 |
Fastest train 14h 59m |
First train 1:05 AM |
Last train 5:40 PM |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Wed |
Least Busy Day Sat |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
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Prague’s ceremonial heart, surrounded by historic facades, churches, and major landmarks; essential for first-time visitors.
A picturesque historic district below Prague Castle with baroque streets, embassies, gardens, and a romantic atmosphere.
A major boulevard-like square central to modern Czech history, shopping, and public life, anchored by the National Museum.
Marinated beef sirloin with creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the best-known classic Czech festive dishes.
Roast pork served with dumplings and braised cabbage. This is a cornerstone of traditional Czech home-style cooking and pub menus.
Czech-style goulash is usually a rich beef stew with onions, paprika, and bread dumplings. It is a hearty staple often eaten in historic Prague pubs.
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Well-known Old Town restaurant offering polished Czech classics and seasonal dishes in a stylish but approachable atmosphere.
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Moderate by European standards. Beer, transit, and casual meals are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. No tip needed for counter service, though small change is appreciated.
Official public transport app
Prague hlavní nádraží -> Old Town Square, Prague
Find answers to the most common questions about traveling from Pisa to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

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