Travel Information
Compare train, bus, and flight for Pisa to Prague
Omio recommends booking the flight as it is the most popular option from Pisa to Prague among Omio's users. If you are prioritising price, take the train, with an average ticket price of $12 For those with little time, consider booking a flight, which has an average total journey time of 5h 23m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.8 - 1.9kg. Average ticket prices depend on the travel mode: a train costs an average of $12, while a flight costs an average of $553.
Distance: 479 miles (771 km)
Compare flight with
Most popular Flight | Bus | Train | Driving |
|---|---|---|---|
$553 Average price | $122 Average price | $12 Average price Cheapest | $283 Average price (fuel + tolls) |
5h 23m Average total duration Fastest 3h 23m Onboard + 2h 0m Additional time* | 17h 24m Average total duration 16h 54m Onboard + 30m Additional time* | 14h 43m Average total duration 14h 13m Onboard + 30m Additional time* | 11h 54m Average total duration (door-to-door) |
2.3 - 4.6kg CO2 emissions | 0.8 - 1.9kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Pisa to Prague
Compare the available ways to get from Pisa to Prague, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Pisa to Prague:
A train is $110 (€92) less than a bus for this route with tickets for a bus from Pisa to Prague costing on average $122 (€102).
A train is $541 (€453) less than a flight for this route with tickets for a flight from Pisa to Prague costing on average $553 (€462).
Other travel options to Prague take longer:
Train takes on average 14h 43m.
Bus takes on average 17h 24m.
You'll arrive about 8h 31m sooner (3h 23m by flight vs 11h 54m by car). Tickets start at around $553 (€462) compared to roughly $283 (€237) in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Pisa to Prague
How to get from Pisa to Prague by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus5:10 PM 16h15 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 9:25 AM Praha, ÚAN Florenc $85 1 One-way 0 transfers
Cheapest
FlixBus5:10 PM 16h15 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 9:25 AM Praha, ÚAN Florenc $85 1 One-way 0 transfers
Fastest
Regionale 18260+
FRECCIAROSSA 9401+
Regionale 20445+
QS10096:29 AM 9h31 Pisa Centrale 4:00 PM Prague Vaclav Havel Airport $181 1 One-way 3 transfers
Other options
FlixBus · FlixBus · FlixBus7:15 AM 20h00 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 3:15 AM Prague, Central Train Station $129 1 One-way 2 transfers
FlixBus · FlixBus · FlixBus9:40 AM 21h20 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 7:00 AM Prague, Central Train Station $133 1 One-way 2 transfers
FlixBus · FlixBus · FlixBus9:40 AM 20h05 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 5:45 AM Praha, ÚAN Florenc $134 1 One-way 2 transfers
Regionale Veloce 4125 · Regionale 20443+
QS10095:45 AM 10h15 Pisa Centrale 4:00 PM Prague Vaclav Havel Airport $153 1 One-way 2 transfers
InterCityNotte 899+
Regionale 12503 · Regionale 5046+
QS10092:21 AM 13h39 Pisa Centrale 4:00 PM Prague Vaclav Havel Airport $156 1 One-way 3 transfers
InterCityNotte 899+
Regionale 20391+
QS10092:21 AM 13h39 Pisa Centrale 4:00 PM Prague Vaclav Havel Airport $156 1 One-way 2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Pisa to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Prague.

This is compared to other travel options from Pisa to Prague:
A train is $110 (€92) less than a bus for this route with tickets for a bus from Pisa to Prague costing on average $122 (€102).
A train is $541 (€453) less than a flight for this route with tickets for a flight from Pisa to Prague costing on average $553 (€462).
Other travel options to Prague take longer:
Train takes on average 14h 43m.
Bus takes on average 17h 24m.
- Around 21 trains per day.
- Around 11 flights per day.
- Around 10 buses per day.
However, we recommend checking specific travel dates for your route between Pisa and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Pisa Centrale and arrive in Prague hlavní nádraží.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Prague, Central Train Station.
- Travel with FlixBus to go to Prague by bus.
- Travel with Deutsche Bahn to go to Prague by train.
- Travel with Transavia France, Air Dolomiti, British Airways, Eurowings, Malta Air, Buzz, Ryanair to go to Prague by flight.
- 1 direct buses per day with FlixBus.
- 1 direct flights per day with Malta Air, Buzz, Ryanair.
Travelling from Pisa to Prague: related information
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