Travel Information
Compare train, bus, and flight for Pisa to Prague
Omio recommends booking the flight as it is the most popular option from Pisa to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $62. For those with little time consider booking a flight which can get you there in 1h 52m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.8 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of $62, and a train costs an average of $239.
Distance: 479 miles (771 km)
Compare flight with
Most popular Flight | Bus | Train | Driving |
|---|---|---|---|
$213 Average price | $94 Average price Cheapest | $259 Average price | $285 Average price (fuel + tolls) |
4h 52m Average total duration Fastest 1h 52m Onboard + 3h 0m Additional time* | 17h 16m Average total duration 16h 46m Onboard + 30m Additional time* | 20h 33m Average total duration 20h 3m Onboard + 30m Additional time* | 11h 54m Average total duration (door-to-door) |
2.3 - 4.6kg CO2 emissions | 0.8 - 1.9kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental | |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Prague:
A bus is $119 (€97) less than a flight for this route with tickets for a flight from Pisa to Prague costing on average $213 (€175).
A bus is $165 (€135) less than a train for this route with tickets for a train from Pisa to Prague costing on average $259 (€212).
Other travel options to Prague take longer:
Bus takes on average 16h 46m.
Train takes on average 20h 3m.
Travel optionsfrom Pisa to Prague
How to get from Pisa to Prague by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus · FlixBus10:00 PM19h30Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:30 PMPrague, Central Train Station$901One-way2 transfers
Cheapest
FlixBus · FlixBus · FlixBus10:00 PM19h30Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:30 PMPrague, Central Train Station$901One-way2 transfers
Fastest
LH7403+
LH14026:35 PM4h40Pisa International Airport11:15 PMPrague Vaclav Havel Airport$4371One-way1 transfer
Other options
FlixBus · FlixBus · FlixBus10:00 PM19h45Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:45 PMPraha, ÚAN Florenc$901One-way2 transfers
FlixBus · FlixBus · FlixBus9:40 AM21h20Pisa, Via delle Fiamme Gialle (Park Pietrasantina)7:00 AMPrague, Central Train Station$921One-way2 transfers
FlixBus · FlixBus · FlixBus10:00 PM22h20Pisa, Via delle Fiamme Gialle (Park Pietrasantina)8:20 PMPraha, Na Knížecí$951One-way2 transfers
Regionale Veloce 4125 · Regionale 20443+
QS10095:37 AM10h23Pisa Centrale4:00 PMPrague Vaclav Havel Airport$1551One-way2 transfers
Regionale Veloce 4125 · Regionale 20447+
QS10095:37 AM10h23Pisa Centrale4:00 PMPrague Vaclav Havel Airport$1551One-way2 transfers
InterCityNotte 799+
Regionale 20391+
QS10092:21 AM13h39Pisa Centrale4:00 PMPrague Vaclav Havel Airport$1591One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Pisa to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Prague.

This is compared to other travel options from Pisa to Prague:
A bus is $119 (€97) less than a flight for this route with tickets for a flight from Pisa to Prague costing on average $213 (€175).
A bus is $165 (€135) less than a train for this route with tickets for a train from Pisa to Prague costing on average $259 (€212).
Other travel options to Prague take longer:
Bus takes on average 16h 46m.
Train takes on average 20h 3m.
- Around 12 buses per day.
- Around 7 flights per day.
- Around 4 trains per day.
However, we recommend checking specific travel dates for your route between Pisa and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Prague Vaclav Havel Airport.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Prague, Central Train Station.
- Travel with Malta Air, Buzz, Ryanair, Air Dolomiti to go to Prague by flight.
- Travel with FlixBus to go to Prague by bus.
- Travel with Regionale to go to Prague by train.
- 1 direct flights per day with Malta Air, Buzz, Ryanair.
- 1 direct buses per day with FlixBus.
Travelling from Pisa to Prague: related information
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