Travel Information
Compare train, bus, and flight for Pisa to Prague
Omio recommends booking the flight as it is the most popular option from Pisa to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $62. For those with little time consider booking a flight which can get you there in 2h 26m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.8 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of $62, and a train costs an average of $229.
Distance: 479 miles (771 km)
Compare flight with
Most popular Flight | Bus | Train | Driving |
|---|---|---|---|
$127 Average price | $101 Average price Cheapest | $263 Average price | $294 Average price (fuel + tolls) |
5h 26m Average total duration Fastest 2h 26m Onboard + 3h 0m Additional time* | 17h 16m Average total duration 16h 46m Onboard + 30m Additional time* | 20h 44m Average total duration 20h 14m Onboard + 30m Additional time* | 11h 54m Average total duration (door-to-door) |
2.3 - 4.6kg CO2 emissions | 0.8 - 1.9kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental | |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Prague:
A bus is $26 (€21) less than a flight for this route with tickets for a flight from Pisa to Prague costing on average $127 (€102).
A bus is $162 (€129) less than a train for this route with tickets for a train from Pisa to Prague costing on average $263 (€210).
Other travel options to Prague take longer:
Bus takes on average 16h 46m.
Train takes on average 20h 14m.
Travel optionsfrom Pisa to Prague
How to get from Pisa to Prague by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Prague is by taking a bus because it’s the best combination of price and speed.
4:20 PM16h05Pisa8:25 AMPrague$831One-way0 transfers
Cheapest
4:20 PM16h05Pisa8:25 AMPrague$831One-way0 transfers
Fastest
4:20 PM16h05Pisa8:25 AMPrague$831One-way0 transfers
Other options
3:45 PM16h40Pisa8:25 AMPrague$841One-way0 transfers
9:00 PM19h45Pisa4:45 PMPrague$1231One-way0 transfers
5:10 PM20h25Pisa1:35 PMPrague$1321One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Pisa to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Prague.

This is compared to other travel options from Pisa to Prague:
A bus is $26 (€21) less than a flight for this route with tickets for a flight from Pisa to Prague costing on average $127 (€102).
A bus is $162 (€129) less than a train for this route with tickets for a train from Pisa to Prague costing on average $263 (€210).
Other travel options to Prague take longer:
Bus takes on average 16h 46m.
Train takes on average 20h 14m.
- Around 12 buses per day.
- Around 7 flights per day.
- Around 5 trains per day.
However, we recommend checking specific travel dates for your route between Pisa and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Prague Vaclav Havel Airport.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Prague, Central Train Station.
- Travel with FlixBus to go to Prague by bus.
- Travel with Regionale to go to Prague by train.
- Travel with Malta Air, Buzz, Ryanair, Norwegian Air Shuttle, Air Dolomiti to go to Prague by flight.
- 1 direct buses per day with FlixBus.
- 1 direct flights per day with Malta Air, Buzz.
Travelling from Pisa to Prague: related information
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