- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.







Cheapest price
$31
Average price
$126
Fastest journey
7h 40m
Average duration
9h 15m
Trains per day
7
Distance
410 km
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $15. For those with little time consider booking a flight which can get you there in 3h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $15, and a flight costs an average of $176.
Distance: 254 miles (409 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$116 Average price | $43 Average price Cheapest | $279 Average price | $112 Average price (fuel + tolls) |
6h 32m Average total duration 6h 2m Onboard + 30m Additional time* | 7h 36m Average total duration 7h 6m Onboard + 30m Additional time* | 6h 19m Average total duration Fastest 3h 19m Onboard + 3h 0m Additional time* | 5h 38m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.2 - 2.5kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Prague:
A bus is $73 (€60) less than a train for this route with tickets for a train from Frankfurt am Main to Prague costing on average $116 (€95).
A bus is $235 (€193) less than a flight for this route with tickets for a flight from Frankfurt am Main to Prague costing on average $279 (€228).
Other travel options to Prague take longer:
Train takes on average 6h 2m.
Bus takes on average 7h 6m.
Tickets start at around $116 (€95) compared to roughly $112 (€92) in fuel and tolls — a saving of about $-4.03 (€-3.30). The journey takes 6h 2m versus 5h 38m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Frankfurt am Main to Prague trains for today, Thursday, July 16. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
ICE 1653 · RJ 179 | On time 2:31 PM Frankfurt (Main) Hbf | 9h00 | 11:31 PM Prague hlavní nádraží | 1 transfer | |
ICE 1653 · rj 179 | On time 2:31 PM Frankfurt (Main) Hbf | 9h00 | 11:31 PM Prague hlavní nádraží | 1 transfer | |
ICE 629 · R 3597 · EC 363 | Delayed 1:07 PM 2:41 PMFrankfurt Airport long-distance station | 7h40 | 10:21 PM Prague hlavní nádraží | 2 transfers | |
LE235 | 3:03 PM Frankfurt South station | 10h04 | 1:07 AM Prague hlavní nádraží | 0 transfersDirect | |
LE235 | 3:03 PM Frankfurt South station | 10h18 | 1:21 AM Praha-Vršovice | 0 transfersDirect | |
ICE 1655 · NJ 457 | On time 4:31 PM Frankfurt (Main) Hbf | 7h45 | 12:16 AM Prague-Holešovice | 1 transfer | |
ICE 2506 · rj 479 | On time 6:30 PM Frankfurt (Main) Hbf | 10h55 | 5:25 AM Prague hlavní nádraží | 1 transfer | |
| Friday, July 17 | |||||
ICE 1272 · EC 459 | Delayed 12:04 AM Frankfurt Airport long-distance station | 9h21 | 7:25 AM 7:25 AMPrague hlavní nádraží | 1 transfer | |
ICE 698 · RJ 173 | 3:09 AM Frankfurt Airport long-distance station | 10h16 | 1:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 2824 · RJ 173 | 3:09 AM Frankfurt Airport long-distance station | 10h16 | 1:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 698 · RJ 173 | 3:31 AM Frankfurt (Main) Hbf | 9h54 | 1:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 2824 · RJ 173 | 3:31 AM Frankfurt (Main) Hbf | 9h54 | 1:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 698 · 58203 · 3557+ 355 | 3:31 AM Frankfurt (Main) Hbf | 10h50 | 2:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 698 · 58203 · 3557+ 359 | 3:31 AM Frankfurt (Main) Hbf | 14h50 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 698 · 58203 · 3557+ 357 | 3:31 AM Frankfurt (Main) Hbf | 12h50 | 4:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 827 · 3557+ 353 | On time 4:38 AM Frankfurt Airport long-distance station | 7h43 | 12:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 827 · R 3557 · EC 353 | On time 4:38 AM Frankfurt Airport long-distance station | 7h43 | 12:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 827 · 3557+ 353 | On time 4:54 AM Frankfurt (Main) Hbf | 7h27 | 12:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 827 · 3557+ 355 | On time 4:54 AM Frankfurt (Main) Hbf | 9h27 | 2:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 827 · 3557+ 359 | On time 4:54 AM Frankfurt (Main) Hbf | 13h27 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 827 · 3557+ 357 | On time 4:54 AM Frankfurt (Main) Hbf | 11h27 | 4:21 PM Prague hlavní nádraží | 2 transfers | |
S8 · ICE 1555 · ICE 581 · 3561 | 6:00 AM Frankfurt am Main Flughafen | 8h21 | 2:21 PM Prague hlavní nádraží | 4 transfers | |
ICE 1555 · rj 175 | On time 6:28 AM Frankfurt (Main) Hbf | 8h47 | 3:15 PM Prague-Holešovice | 1 transfer | |
4603 · ICE 581 · 3561+ 357 | 6:35 AM Frankfurt (Main) Hbf | 9h46 | 4:21 PM Prague hlavní nádraží | 3 transfers | |
4603 · ICE 581 · 3561+ 359 | 6:35 AM Frankfurt (Main) Hbf | 11h46 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 523 · 3561+ 355 | On time 6:41 AM Frankfurt Airport long-distance station | 7h40 | 2:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 523 · R 3561 · EC 355 | On time 6:41 AM Frankfurt Airport long-distance station | 7h40 | 2:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 523 · 3561+ 355 | On time 6:57 AM Frankfurt (Main) Hbf | 7h24 | 2:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 523 · 3561+ 359 | On time 6:57 AM Frankfurt (Main) Hbf | 11h24 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 523 · 3561+ 357 | On time 6:57 AM Frankfurt (Main) Hbf | 9h24 | 4:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 378 · IC 2445 · RJ 175 | On time 7:15 AM Frankfurt (Main) Hbf | 8h00 | 3:15 PM Prague-Holešovice | 2 transfers | |
ICE 525 · 3563+ 357 | On time 7:57 AM Frankfurt (Main) Hbf | 8h24 | 4:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 525 · 3567+ 359 | On time 7:57 AM Frankfurt (Main) Hbf | 10h24 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 525 · 3565+ 359 | On time 7:57 AM Frankfurt (Main) Hbf | 10h24 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 1557 · RJ 383 | On time 8:31 AM Frankfurt (Main) Hbf | 8h54 | 5:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 1557 · rj 383 | On time 8:31 AM Frankfurt (Main) Hbf | 8h54 | 5:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 527 · 3565+ 357 | On time 8:41 AM Frankfurt Airport long-distance station | 7h40 | 4:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 527 · R 3565 · EC 357 | On time 8:41 AM Frankfurt Airport long-distance station | 7h40 | 4:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 527 · 3565+ 357 | On time 8:57 AM Frankfurt (Main) Hbf | 7h24 | 4:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 527 · 3567+ 361 | On time 8:57 AM Frankfurt (Main) Hbf | 11h24 | 8:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 527 · 3567+ 359 | On time 8:57 AM Frankfurt (Main) Hbf | 9h24 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 527 · 3565+ 359 | On time 8:57 AM Frankfurt (Main) Hbf | 9h24 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 376 · IC 2443 · RJ 383 | On time 9:15 AM Frankfurt (Main) Hbf | 8h10 | 5:25 PM Prague hlavní nádraží | 2 transfers | |
4609 · ICE 785 · 3567+ 359 | 9:28 AM Frankfurt (Main) Hbf | 8h53 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
4609 · ICE 785 · 3567+ 361 | 9:28 AM Frankfurt (Main) Hbf | 10h53 | 8:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 529 · 3567+ 359 | On time 9:57 AM Frankfurt (Main) Hbf | 8h24 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 529 · 3567+ 361 | On time 9:57 AM Frankfurt (Main) Hbf | 10h24 | 8:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 759 · rj 177 | On time 10:28 AM Frankfurt (Main) Hbf | 8h47 | 7:15 PM Prague-Holešovice | 1 transfer | |
ICE 621 · 3569+ 359 | On time 10:41 AM Frankfurt Airport long-distance station | 7h40 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 621 · R 3569 · EC 359 | On time 10:41 AM Frankfurt Airport long-distance station | 7h40 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 621 · 3569+ 359 | On time 10:57 AM Frankfurt (Main) Hbf | 7h24 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 374 · IC 2441 · RJ 177 | On time 11:15 AM Frankfurt (Main) Hbf | 8h00 | 7:15 PM Prague-Holešovice | 2 transfers | |
ICE 27 · 3499+ 361 | 12:02 PM Frankfurt Airport long-distance station | 8h19 | 8:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 1651 · RJ 385 | On time 12:28 PM Frankfurt (Main) Hbf | 8h57 | 9:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 1651 · rj 385 | On time 12:28 PM Frankfurt (Main) Hbf | 8h57 | 9:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 2571 · RJ 385 | On time 12:28 PM Frankfurt (Main) Hbf | 8h57 | 9:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 625 · 3499+ 361 | On time 12:41 PM Frankfurt Airport long-distance station | 7h40 | 8:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 625 · R 3499 · EC 361 | On time 12:41 PM Frankfurt Airport long-distance station | 7h40 | 8:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 625 · 3499+ 361 | On time 12:57 PM Frankfurt (Main) Hbf | 7h24 | 8:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 372 · IC 2049 · RJ 385 | On time 1:15 PM Frankfurt (Main) Hbf | 8h10 | 9:25 PM Prague hlavní nádraží | 2 transfers | |
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Frankfurt am Main to Prague run on average 16 times per day, taking around 6h 2m. Cheap train tickets for this journey start at $36 (€30) but you can travel from only $15 (€13) by bus.
The earliest train runs at 00:04, the last at 23:57. The fastest train covers the 254 miles (409 km) distance in 6h 59m.
Distance 254 miles (409 km) |
Average train duration 6h 2m |
Cheapest ticket price $36 (€30) |
Trains per day 16 |
Fastest train 6h 59m |
First train 12:04 AM |
Last train 11:57 PM |
Cheapest Month Dec |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sat |
Best time to book 84 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Praha hlavní nádraží -> Václavské náměstí, Prague
Find answers to the most common questions about traveling from Frankfurt am Main to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Frankfurt am Main to Prague trains use the Frankfurt (Main) Hbf to Praha hlavní nádraží station pair, with some services arriving at Praha-Holesovice. Use this guide to compare Frankfurt am Main and Prague train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Frankfurt (Main) Hbf is 1 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt (Main) Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: asiagourmet, Burger King, Ciao Bella, Coffee Fellows, Crepes de France Express, dean&david, Starbucks, Uddin's Sky Sportsbar, McDonald's, Dunkin Donuts, & many more
Free Wi-Fi in the station. ATMs are available at Frankfurt (Main) Hbf.
Ticket office support is available at Frankfurt (Main) Hbf. Information desks are located opposite Platforms 12 and 13.
Luggage storage is luggage lockers are located in the main hall. Lost and found is available at the station.
Available at Frankfurt (Main) Hbf: Parking, Taxis, WC.
Available at Frankfurt (Main) Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Frankfurt (Main) Hbf: Step-free access and step markings. Contact the Mobility Service Centre at +49 3065212888 or [email protected].
Nearby hotels include Hotel Cristall, Grand Hotel Empire, Hotel Carlton.
Frankfurt (Main) Süd is 1 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt (Main) Süd has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Merals Imbiss, Bootshaus am Eisernen Steg, Freigut, Holbein's
Wi-Fi is available at Frankfurt (Main) Süd. ATMs are available at Frankfurt (Main) Süd.
Ticket office support is available at Frankfurt (Main) Süd. Information desks are available at Frankfurt (Main) Süd.
Luggage storage is available at Frankfurt (Main) Süd. Lost and found is available at the station.
Available at Frankfurt (Main) Süd: Parking, Taxis, WC.
Available at Frankfurt (Main) Süd: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Frankfurt (Main) Süd.
Nearby hotels include Hotel am Berg, Leonardo Royal Hotel Frankfurt, Hotel Ritter, Lindner Main Plaza.
Frankfurt Flughafen Fernbf is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt Flughafen Fernbf has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Käfer's, McDonald's, Asia Snack Box
Free. ATMs are available in the train station.
Ticket office support is available at Frankfurt Flughafen Fernbf. Information desks are located in the main hall.
Luggage storage is available at Frankfurt Flughafen Fernbf. Lost and found is available at the station.
Available at Frankfurt Flughafen Fernbf: Parking, Taxis, WC.
Available at Frankfurt Flughafen Fernbf: Bike Parking, Car Rental.
Accessibility facilities are available at Frankfurt Flughafen Fernbf: Elevators, ramps.
Nearby hotels include Sheraton Frankfurt Airport Hotel, Hilton Frankfurt Airport, Hilton Garden Inn Frankfurt Airport.
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Na Kovárně, Cross Club
Free. ATMs are available in the train station.
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Available at Praha-Holesovice: Parking, Taxis, WC.
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Kotleta, Café Imperial
Free. ATMs are available in the train station.
Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.
Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.
Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.
Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.
Here are some other resources that might have the information you need