- Must visit
National Museum
Prague’s main museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, science, and history collections.
Cheapest price
$110
Average price
$218
Fastest journey
10 h 56 m
Average duration
11 h 12 m
Trains per day
39
Distance
717 km
The best way to find a cheap train ticket from Brussels to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Prague will cost around $218 if you buy it on the day, but the cheapest tickets can be found for only $110.
It's difficult to get from Brussels to Prague without transferring at least 2 times.
ICE 315 · ICE 651 · RJ 179
ICE 315 · ICE 721 · 5293 · IC 567
ICE 11 · ICE 759 · rj 177
ICE 11 · ICE 759 · rj 177
ICE 15 · ICE 1653 · rj 179
ICE 315 · ICE 721 · 5293 · IC 567
ICE 11 · ICE 555 · rj 383
ICE 315 · ICE 651 · RJ 179
ICE 315 · ICE 651 · rj 179
ICE 315 · ICE 1655 · NJ 457Omio recommends booking the flight as it is the most popular option from Brussels to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $57. For those with little time consider booking a flight which can get you there in 2h 5m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $57, and a flight costs an average of $33.
Distance: 445 miles (717 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$128 Average price | $194 Average price | $84 Average price Cheapest | $181 Average price (fuel + tolls) |
13h 20m Average total duration 12h 50m Onboard + 30m Additional time* | 5h 5m Average total duration Fastest 2h 5m Onboard + 3h 0m Additional time* | 15h 45m Average total duration 15h 15m Onboard + 30m Additional time* | 8h 38m Average total duration (door-to-door) |
0.2 - 0.6kg CO2 emissions Lowest | 2.2 - 4.3kg CO2 emissions | 0.7 - 1.8kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Brussels to Prague:
A bus is $44 (€36) less than a train for this route with tickets for a train from Brussels to Prague costing on average $128 (€105).
A bus is $110 (€90) less than a flight for this route with tickets for a flight from Brussels to Prague costing on average $194 (€159).
Other travel options to Prague take longer:
Train takes on average 12h 50m.
Bus takes on average 15h 15m.
Tickets start at around {cheapestPrice} compared to roughly {drivingPriceInCents} in fuel and tolls — a saving of about {savingsAmount}. The journey takes {durationInMinutes} versus {drivingDurationInMinutes} by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Direct services run with Alibus, European Sleeper.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Brussels to Prague trains for today, Friday, July 10. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
453 | 7:22 PM Brussels-Midi | 16h23 | 11:45 AM Prague hlavní nádraží | 0 transfersDirect | |
ICE 319 · ICE 698 · S 37559 · IC 2449 | On time 8:22 PM Brussels-Midi | 15h03 | 11:25 AM Prague hlavní nádraží | 4 transfers | |
ICE 319 · ICE 698 · S5 · IC 2449 | On time 8:22 PM Brussels-Midi | 15h03 | 11:25 AM Prague hlavní nádraží | 4 transfers | |
ICE 319 · ICE 619+ 353 | On time 8:22 PM Brussels-Midi | 15h59 | 12:21 PM Prague hlavní nádraží | 2 transfers | |
| Saturday, July 11 | |||||
IC 522 · R 5005 · RE 26809 · ICE 555 | 12:20 AM Brussels-Midi | 17h05 | 5:25 PM Prague hlavní nádraží | 4 transfers | |
IC 522 · R 5005 · 26809 · ICE 555 | On time 12:20 AM Brussels-Midi | 17h05 | 5:25 PM Prague hlavní nádraží | 4 transfers | |
IC 522 · R 5005 · R 10312 · ICE 545 | 12:20 AM Brussels-Midi | 17h05 | 5:25 PM Prague hlavní nádraží | 4 transfers | |
ICE 11 · ICE 555 · rj 383 | 6:23 AM Brussels-Midi | 11h02 | 5:25 PM Prague hlavní nádraží | 2 transfers | |
ICE 11 · ICE 759 · rj 177 | On time 6:23 AM Brussels-Midi | 12h52 | 7:15 PM Prague-Holešovice | 2 transfers | |
ICE 11 · ICE 621 · R 3569 · EC 359 | On time 6:23 AM Brussels-Midi | 11h58 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 11 · ICE 621 · 3569+ 359 | On time 6:23 AM Brussels-Midi | 11h58 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 11 · ICE 759 · rj 177 | On time 6:23 AM Brussels-Midi | 12h52 | 7:15 PM Prague-Holešovice | 2 transfers | |
ICE 11 · ICE 621 · R 3569 · EC 359 | On time 6:23 AM Brussels-Midi | 11h58 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 11 · ICE 621 · R 3569 · EC 359 | On time 6:23 AM Brussels-Midi | 11h58 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 11 · ICE 759 · rj 177 | On time 6:23 AM Brussels-Midi | 12h52 | 7:15 PM Prague-Holešovice | 2 transfers | |
ICE 11 · S12 · ICE 557 · RJ 177 | On time 6:23 AM Brussels-Midi | 12h52 | 7:15 PM Prague-Holešovice | 3 transfers | |
ICE 11 · ICE 621 · 3569+ 359 | On time 6:23 AM Brussels-Midi | 11h58 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
IC 505 · R 18921 · RE 26413 · ICE 547 | 6:56 AM Brussels-Midi | 12h19 | 7:15 PM Prague-Holešovice | 4 transfers | |
ICE 13 · ICE 1651 · RJ 385 | On time 8:25 AM Brussels-Midi | 13h00 | 9:25 PM Prague hlavní nádraží | 2 transfers | |
ICE 13 · ICE 625 · 3573+ 361 | On time 8:25 AM Brussels-Midi | 11h56 | 8:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 13 · ICE 1651 · rj 385 | On time 8:25 AM Brussels-Midi | 13h00 | 9:25 PM Prague hlavní nádraží | 2 transfers | |
ICE 13 · ICE 625 · R 3573 · EC 361 | On time 8:25 AM Brussels-Midi | 11h56 | 8:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 15 · ICE 1653 · RJ 179 | On time 10:25 AM Brussels-Midi | 13h06 | 11:31 PM Prague hlavní nádraží | 2 transfers | |
ICE 15 · ICE 629 · 3577+ 363 | On time 10:25 AM Brussels-Midi | 11h57 | 10:22 PM Prague hlavní nádraží | 3 transfers | |
ICE 15 · ICE 629 · R 3577 · EC 363 | On time 10:25 AM Brussels-Midi | 11h59 | 10:24 PM Prague hlavní nádraží | 4 transfers | |
ICE 15 · ICE 1653 · rj 179 | On time 10:25 AM Brussels-Midi | 13h06 | 11:31 PM Prague hlavní nádraží | 2 transfers | |
ICE 315 · ICE 651 · RJ 179 | 12:25 PM Brussels-Midi | 11h06 | 11:31 PM Prague hlavní nádraží | 2 transfers | |
ICE 315 · ICE 721 · 5293 · IC 567 | On time 12:25 PM Brussels-Midi | 10h56 | 11:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 315 · ICE 651 · rj 179 | 12:25 PM Brussels-Midi | 11h06 | 11:31 PM Prague hlavní nádraží | 2 transfers | |
ICE 315 · ICE 1655 · NJ 457 | On time 12:25 PM Brussels-Midi | 12h01 | 12:26 AM Prague hlavní nádraží | 2 transfers | |
ICE 315 · ICE 1655 · NJ 457 | On time 12:25 PM Brussels-Midi | 12h01 | 12:26 AM Prague hlavní nádraží | 2 transfers | |
ICE 315 · ICE 1655 · NJ 457 | On time 12:25 PM Brussels-Midi | 11h51 | 12:16 AM Prague-Holešovice | 2 transfers | |
ICE 317 · S12 · ICE 957 · RJ 479 | On time 4:25 PM Brussels-Midi | 13h00 | 5:25 AM Prague hlavní nádraží | 3 transfers | |
ICE 317 · RE 26431 · ICE 957 · rj 479 | On time 4:25 PM Brussels-Midi | 13h00 | 5:25 AM Prague hlavní nádraží | 4 transfers | |
ICE 19+ 24369+ EC 459 | On time 6:25 PM Brussels-Midi | 15h00 | 9:25 AM Prague hlavní nádraží | 2 transfers | |
ICE 19 · R 4542 · EC 459 | On time 6:25 PM Brussels-Midi | 15h00 | 9:25 AM Prague hlavní nádraží | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Brussels to Prague run on average 6 times per day, taking around 12h 50m. Cheap train tickets for this journey start at $13 (€11) if you book in advance.
The earliest train runs at 00:33, the last at 23:58. The fastest train covers the 445 miles (717 km) distance in 10h 50m.
Distance 445 miles (717 km) |
Average train duration 12h 50m |
Cheapest ticket price $13 (€11) |
Trains per day 6 |
Fastest train 10h 50m |
First train 12:33 AM |
Last train 11:58 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Sun |
Best time to book 77 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s main museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, science, and history collections.
One of Prague’s most significant museum institutions, preserving Jewish history through synagogues, exhibitions, and the Old Jewish Cemetery.
A leading city gallery in a Gothic landmark on Old Town Square, hosting major modern and contemporary art exhibitions.
Prague’s historic heart, surrounded by major monuments and lively at all times of day; essential for first-time visitors.
A picturesque Baroque district below Prague Castle with quiet lanes, embassies, gardens, and classic city charm.
A major boulevard-like square central to modern Czech history, shopping, and the city’s urban energy.
Marinated beef sirloin with a creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the most iconic Czech Sunday and festive dishes.
Roast pork served with bread dumplings and braised sauerkraut. This is a classic Czech pub and home-style meal strongly associated with Bohemian cooking.
Czech goulash is a rich beef stew seasoned with onion and paprika, usually served with bread dumplings. It is a staple of traditional Prague taverns and beer halls.
A Michelin-starred restaurant offering contemporary Czech fine dining with seasonal ingredients, tasting menus, and a sophisticated modern atmosphere.
An elegant grand café offering refined Czech and Central European dishes, excellent breakfasts, and classic pastries in a beautifully restored interior.
A well-regarded Old Town restaurant focused on updated Czech cuisine, including svíčková and goulash, in a polished but approachable setting.
Moderate for Europe: beer, transit, and casual meals are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. No tip is expected for fast food, but small change is appreciated in cafés.
Official public transport app
Prague hlavní nádraží, Prague -> Old Town Square, Prague
Find answers to the most common questions about traveling from Brussels to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

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