Brussels to Prague train with Deutsche Bahn (ICE,EC,IC,RE,RB)

Wed, Feb 25
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Deutsche Bahn
European Sleeper
České dráhy
Alex
European Sleeper
1,000+ travel companies
Deutsche Bahn
European Sleeper
České dráhy
Alex
European Sleeper
1,000+ travel companies
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The cheapest and fastest trains from Brussels to Prague

Showing times and prices for Feb 25

Cheapest price

$130

Average price

$181

Fastest journey

10 h 50 m

Average duration

11 h 50 m

Trains per day

5

Distance

717 km

Cheap tickets

The best way to find a cheap train ticket from Brussels to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Brussels to Prague will cost around $181 if you buy it on the day, but the cheapest tickets can be found for only $130.

Fast trains

Of the 5 trains that leave Brussels for Prague on Wed, Feb 25, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Wed, Feb 25 the direct trains cover the 717 km distance in an average of 11 h 50 m but if you time it right, some trains will get you there in just 10 h 50 m .

On Wed, Feb 25 the slowest trains will take 15 h 29 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

European Sleeper453
07:22PM15h29
Brussels-Midi
10:51AMPrague hlavní nádraží
$1301One-way
0 transfers
České dráhyICE 15 · ICE 549 · rj 385
10:25AM11h00
Brussels-Midi
09:25PMPrague hlavní nádraží
$1441One-way
2 transfers
České dráhyICE 13 · ICE 547 · rj 177
08:25AM10h50
Brussels-Midi
07:15PMPrague-Holešovice
$1441One-way
2 transfers
Deutsche BahnICE 15 · ICE 549 · RJ 385
10:25AM11h00
Brussels-Midi
09:25PMPrague hlavní nádraží
$2431One-way
2 transfers
Deutsche BahnICE 13 · ICE 547 · RJ 177
08:25AM10h50
Brussels-Midi
07:15PMPrague-Holešovice
$2431One-way
2 transfers

Travel Information

Compare train, bus, and flight for Brussels to Prague

Omio recommends booking the flight as it is the most popular option from Brussels to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $51. For those with little time consider booking a flight which can get you there in 2h 6m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $51, and a flight costs an average of $25.

Distance: 445 miles (717 km)

Compare train with

Train
Most popular
Flight
Bus

$145

Average price

$146

Average price

$83

Average price

Cheapest

13h 15m

Average total duration

12h 45m

Onboard

+

30m

Additional time*

5h 6m

Average total duration

Fastest

2h 6m

Onboard

+

3h 0m

Additional time*

15h 58m

Average total duration

15h 28m

Onboard

+

30m

Additional time*

0.2 - 0.6kg

CO2 emissions

Lowest

2.2 - 4.3kg

CO2 emissions

0.7 - 1.8kg

CO2 emissions

Deutsche Bahn

Most popular train company

Brussels Airlines

Most popular airline

FlixBus

Most popular bus company

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

Brussels to Prague train times

The table below shows live departures for Brussels to Prague trains for tomorrow, Wednesday, February 25. You can also manually refresh the results below to see updated train journeys.

Last updated at 11:43 PM
ProviderDepartsDurationArrivesTransfers
Tickets
czechrailwayICE 13 · ICE 547 · rj 177
On time
7:25 AM Brussels-Midi
10h50
6:15 PM Prague-Holešovice
2 transfers
deutsche_bahnICE 13 · ICE 547 · RJ 177
On time
7:25 AM Brussels-Midi
10h50
6:15 PM Prague-Holešovice
2 transfers
czechrailwayICE 15 · ICE 549 · rj 385
On time
9:25 AM Brussels-Midi
11h00
8:25 PM Prague hlavní nádraží
2 transfers
deutsche_bahnICE 15 · ICE 549 · RJ 385
On time
9:25 AM Brussels-Midi
11h00
8:25 PM Prague hlavní nádraží
2 transfers
esle4536:22 PM Brussels-Midi
15h29
9:51 AM Prague hlavní nádraží0 transfersDirect

Find all the dates and times for this journey

Compare prices and tickets Brussels to Prague by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Wed
Feb 25
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Why should you book Brussels to Prague trains with Omio?

Deutsche Bahn as well as European Sleeper, České dráhy, Alex, European Sleeper and more offer trains services from Brussels to Prague.
Omio is an official ticket reseller for all your travel options from Brussels to Prague.

Why book with Omio vs Deutsche Bahn?

  • Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of European Sleeper, České dráhy, Alex or European Sleeper to find the best option for your trip from Brussels to Prague.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Brussels to Prague.

Why book with Omio over Trainline, Wanderu or Raileurope?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of European Sleeper, České dráhy, Alex or European Sleeper to find the best option for your trip from Brussels to Prague.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Brussels to Prague.

How far in advance should I book train tickets from Brussels to Prague?

The best time to book your train from Brussels to Prague is 91 days before departure. See how prices for trains change on the Brussels to Prague route.
Prices are for one-way tickets for one passenger from Brussels to Prague per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from Brussels to Prague.

Journey information

Overview: Train from Brussels to Prague

BelgiumBelgium
CzechiaCzechia
Icon of train

Trains from Brussels to Prague run on average 6 times per day, taking around 12h 45m. Cheap train tickets for this journey start at $19 (€15) if you book in advance.

The earliest train runs at 00:20, the last at 23:58. The fastest train covers the 445 miles (717 km) distance in 10h 41m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
445 miles (717 km)
Average train duration
12h 45m
Cheapest ticket price
$19 (€15)
Trains per day
6
Fastest train
10h 41m
First train
00:20
Last train
23:58
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Train companies: Deutsche Bahn, European Sleeper, České dráhy, Alex from Brussels to Prague trainsDeutsche Bahn, European Sleeper, České dráhy, Alex trains will get you between Brussels and Prague from $19 (€15). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Deutsche Bahn

About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Duration
10h 50m
Cheapest Price
$94 (€75)
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone

European Sleeper

About
European Sleeper is a Belgian-Dutch train company launched in 2021, operating night train services between Germany and Belgium three times a week, with plans to expand to daily service and extend routes to cities such as Dresden and Prague. Passengers can choose from standard seats, couchettes, or sleeper cabins. Couchettes include free drinks and power outlets, while sleeper cabins offer power outlets and complimentary meals. All tickets are sold as Flex Night fares, which are non-exchangeable but can be canceled up to 48 hours before departure.
Luggage & cancellation policy
Average Duration
15h 29m
Cheapest Price
$100 (€80)
Luggage included
1 piece of hand luggage and 2 pieces of hold luggage included in ticket price
Luggage storage
Luggage racks above seats and at end of carriages
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car serving breakfast, drinks and snacks available for purchase
Seat reservation
Seat or berth reservation mandatory and included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces available, accessible toilets, staff assistance
Pets
Small pets in carriers allowed for free, larger dogs require paid ticket
Quiet zone

Alex

About
agilis is a railway company operating regional trains based in Regensburg in Bavaria since 2010. It operates in the German state of Bavaria connecting cities like Ulm, Ingolstadt, Regensburg and Plattling. They offer single tickets and comfortable trains with some popular routes covering Ulm to Regensburg, Neumarkt to Passau and Ingolstadt to Plattling.
Luggage & cancellation policy
Alex frequency
1 a day
Luggage included
One piece of hand luggage and one larger piece included
Luggage storage
Overhead racks and designated luggage areas
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund for canceled services
Amenities on board the train
Wifi
Food sold onboard
Snack and beverage service available on some routes
Seat reservation
Seat reservations available for additional fee
Toilets
USB plugs
Accessibility
Wheelchair spaces available, assistance for boarding/alighting
Pets
Small pets in carriers travel free, larger dogs require ticket and muzzle
Quiet zone

České dráhy

About
Czech Railways (České dráhy, ČD) is the largest railway company in the Czech Republic, connecting major cities, small towns, and even international destinations across Europe. Its extensive fleet of modern trains ranges from comfortable regional services with A/C and onboard WiFi to high-speed trains offering dining cars, power outlets, and premium seating for long-distance journeys. Czech Railways combines affordability and convenience, making it a popular choice for travelers exploring the Czech Republic and beyond.
Luggage & cancellation policy
Average Duration
10h 41m
Cheapest Price
$19 (€15)
Luggage included
You can transport briefcases, laptops, rucksacks, trolley bags and suitcases on board at no charge.
Additional luggage
Items of luggage must not be so big or heavy that they cannot be carried by a single person, with a generous maximum size of 90 x 60 x 40 cm and a maximum weight of 50kg.
Luggage storage
Luggage can be stored above or below the seat, on the passenger's lap, or in special luggage racks in certain carriages.
Cancellation Policy
Tickets purchased online can be returned free of charge up to 15 minutes before the train's departure.
Refund
If a train is completely canceled, booking fees are refundable, and compensation may be due directly from the rail operator.
Pregnant on board
Being pregnant on board is allowed.
Unaccompagned minor
Automatic compensation for online ČD domestic tickets applies if the system registers a delay of more than 60 minutes at the destination and the ticket was checked by the conductor.
Amenities on board the train
Food sold onboard
A hearty breakfast is included in the ticket price for sleeper carriage services.
Seat reservation
Seat reservations are included with tickets and adjacent seats are booked wherever possible.
Accessibility
Czech Railways is continuously expanding its fleet of wheelchair-accessible carriages and offers assistance for passengers with limited mobility.
Pets
Small pets are allowed on board, but cannot be transported in 1st class, restaurant, or bistro cars.

FAQs: Trains from Brussels to Prague

Find answers to the most common questions about traveling from Brussels to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

FAQs
Train ticket prices from Brussels to Prague can vary. The cheapest ticket starts at $19 (€15), while the average price is around $145 (€116).
The train from Brussels to Prague takes 10h 41m and runs 6 per day.
The distance by train from Brussels to Prague is 445 miles (717 km).
The first train from Brussels to Prague leaves at 12:20 AM.
The last train from Brussels to Prague leaves at 11:58 PM.
Yes, there is a direct train from Brussels to Prague. This service operates 0 times per day, provided by European Sleeper.
Yes, there is a night train from Brussels to Prague.
The train station in Brussels that goes to Prague is Brussels-Midi, which connects to Prague hlavní nádraží.
The cheapest way to get from Brussels to Prague is by train, with a cost of around $19 (€15).
The train journey from Brussels to Prague is moderately scenic, featuring views of rolling hills, quaint villages, and lush forests, particularly as you travel through Germany's countryside.
A day trip from Brussels to Prague is not feasible as the journey takes 10h 41m. The distance between the two cities is 445 miles (717 km) and there are 4 train trips available per day.
In Prague, you can enjoy panoramic views from Petrin Hill and visit attractions like the Petrin Tower and Mirror Maze. Experience the vibrant nightlife in Vinohrady with its trendy bars and cafes, or take a boat cruise on the Vltava River for unique views of the city's landmarks. Delve into Czech history at the National Museum, and enjoy a classical music concert in one of the city's historic venues. Must-see sights include Prague Castle, Charles Bridge, Old Town Square with the Astronomical Clock, St. Vitus Cathedral, and the historic Jewish Quarter.
To fully experience Prague, 3 to 4 days are recommended, allowing time to explore key attractions like Prague Castle, Charles Bridge, Old Town Square, and the Jewish Quarter, as well as enjoy local cuisine and culture.
Yes, you can take the train from Brussels to Prague.

popular train stations

Popular train stations from Brussels to Prague

Brussels
Prague
The major train station for departures in Brussels is Bruxelles-Midi. Find all the information you need to know about services, amenities and connections at Bruxelles-Midi for your trip from Brussels to Prague.
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
ticketOfficeHours
Ticket Office Hours
  • Mon - Sun: 05:45 - 21:30
Wifi
Wifi
  • Wi-Fi is available for a fee.
Lockers
Lockers
  • Baggage storage facility is located across from the Thalys business lounge.
Dining
Dining
  • Pullman Hotel Bar
  • Quick Gare du Midi
  • Subway
  • EXKi Zuid
  • Starbucks
  • Häagen-Dazs
  • Sbarro
  • The Coffee Club
  • The Belgian Chocolate House
  • PAUL
  • & many more
Accessibility
Accessibility
  • Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Hotel
Hotel
  • Les Lofts De Styliste
  • Park Inn by Radisson Brussels Midi
  • Pullman Brussels Centre Midi
Information Desk
Information Desk
  • Located in the main concourse and next to the international platforms.
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • Mon - Sun: 06:15 - 22:00
Wifi
Wifi
  • Free Wi-Fi available in Starbucks.
Lockers
Lockers
  • Luggage lockers are located on Level 0 near Platforms 1 and 2.
Dining
Dining
  • Starbucks
  • Brasserie 28 Brewery
  • Panos
  • Delitraiteur Eat & Go
Accessibility
Accessibility
  • Station has a wide range of facilities for passengers with limited mobility: elevators and escalators to platforms, wheelchair lifts and mobile ramps, barrier-free toilets and accessible parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Hotel
Hotel
  • Hilton Brussels Grand Palace
  • Hotel NH Brussels Carrefour de l'Europe
  • Hôtel The Moon
Ticket Office
Ticket Office
  • Mon - Sun: 06:15 - 22:00
Information Desk
Information Desk
  • Travel Center / information desk is located on the left side from the main entrance.
Public transit options for Bruxelles-Central
  • Metro lines: 1, 5
  • Train lines: IC, Intercity Direct 9200, RER (S1, S2, S3, S6, S8, S10)
Bruxelles-CongresParkingDiningATMTaxisAccessibilityWCHotelBike ParkingBike Rental
Amenities at train station
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Bike ParkingBike Parking
Bike RentalBike Rental
information

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