Brussels to Prague train with Deutsche Bahn (ICE,EC,RE)

Wed, May 27
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Deutsche Bahn
Alibus
České dráhy
alex-Länderbahn und Vogtlandbahn-GmbH
European Sleeper
2,000+ travel companies
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Alibus
České dráhy
alex-Länderbahn und Vogtlandbahn-GmbH
European Sleeper
2,000+ travel companies
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The cheapest and fastest trains from Brussels to Prague

Showing times and prices for May 27

Cheapest price

$16

Average price

$230

Fastest journey

11 h 56 m

Average duration

11 h 56 m

Trains per day

42

Distance

717 km

Cheap tickets

The best way to find a cheap train ticket from Brussels to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Brussels to Prague will cost around $230 if you buy it on the day, but the cheapest tickets can be found for only $16.

Fast trains

Of the 42 trains that leave Brussels for Prague on Wed, May 27, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Wed, May 27 the direct trains cover the 717 km distance in an average of 11 h 56 m but if you time it right, some trains will get you there in just 11 h 56 m .

On Wed, May 27 the slowest trains will take 11 h 56 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • České dráhyNJ 469 · EC 334
    7:06 PM20h33
    Brussels-Midi
    3:39 PMPrague hlavní nádraží
    $161One-way
    1 transfer
  • Deutsche BahnICE 319 · 10342 · ICE 1541 · RJX 251
    8:18 PM14h04
    Brussels-Midi
    10:22 AMPrague-Holešovice
    $1071One-way
    3 transfers
  • Deutsche BahnICE 317 · ICE 590 · 16501 · S1
    4:22 PM16h48
    Brussels-Midi
    9:10 AMPrague hlavní nádraží
    $1071One-way
    5 transfers
  • Deutsche BahnICE 19 · 15542 · EC 459
    6:25 PM15h00
    Brussels-Midi
    9:25 AMPrague hlavní nádraží
    $1131One-way
    2 transfers
  • České dráhyICE 13 · ICE 1651 · rj 385
    8:25 AM13h00
    Brussels-Midi
    9:25 PMPrague hlavní nádraží
    $1181One-way
    2 transfers

Travel Information

Compare train, bus, and flight for Brussels to Prague

Omio recommends booking the flight as it is the most popular option from Brussels to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $59. For those with little time consider booking a flight which can get you there in 2h 5m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $59, and a flight costs an average of $33.

Distance: 445 miles (717 km)

Compare train with

Train
Most popular
Flight
Bus
Driving

$130

Average price

$197

Average price

$86

Average price

Cheapest

$184

Average price

(fuel + tolls)

13h 20m

Average total duration

12h 50m

Onboard

+

30m

Additional time*

5h 5m

Average total duration

Fastest

2h 5m

Onboard

+

3h 0m

Additional time*

15h 45m

Average total duration

15h 15m

Onboard

+

30m

Additional time*

8h 38m

Average total duration

(door-to-door)

0.2 - 0.6kg

CO2 emissions

Lowest

2.2 - 4.3kg

CO2 emissions

0.7 - 1.8kg

CO2 emissions

-

CO2 emissions

Deutsche Bahn

Most popular train company

Ryanair

Most popular airline

FlixBus

Most popular bus company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Brussels to Prague is a bus with an average price of $86 (€69).

This is compared to other travel options from Brussels to Prague:

A bus is $45 (€36) less than a train for this route with tickets for a train from Brussels to Prague costing on average $130 (€105).

A bus is $111 (€90) less than a flight for this route with tickets for a flight from Brussels to Prague costing on average $197 (€159).

The fastest way to travel from Brussels to Prague is by flight with an average journey time of 2h 5m.

Other travel options to Prague take longer:

Train takes on average 12h 50m.

Bus takes on average 15h 15m.

It's helpful to compare your options as there are 3 ways to travel between Brussels and Prague including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Brussels to Prague among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.

Tickets start at around {cheapestPrice} compared to roughly {drivingPriceInCents} in fuel and tolls — a saving of about {savingsAmount}. The journey takes {durationInMinutes} versus {drivingDurationInMinutes} by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.

Direct services run with Alibus, European Sleeper.

Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.

Live departures

Brussels to Prague train times

The table below shows live departures for Brussels to Prague trains for today, Tuesday, May 26. You can also manually refresh the results below to see updated train journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
České dráhyICE 19 · R 4542 · EC 459
On time
6:25 PM Brussels-Midi
15h00
9:25 AM Prague hlavní nádraží		2 transfers
České dráhyICE 319 · ICE 698 · IC 2449 · rj 387
On time
8:25 PM Brussels-Midi
15h00
11:25 AM Prague hlavní nádraží		3 transfers
Deutsche BahnICE 319 · 10342 · ICE 1541 · RJX 251
On time
8:25 PM Brussels-Midi
13h57
10:22 AM Prague-Holešovice		3 transfers
Deutsche BahnICE 319 · ICE 698 · IC 2449 · RJ 387
On time
8:25 PM Brussels-Midi
15h00
11:25 AM Prague hlavní nádraží		3 transfers
Deutsche BahnIC 520 · 18981 · 26401 · ICE 541
On time
9:56 PM Brussels-Midi
15h29
1:25 PM Prague hlavní nádraží		4 transfers
České dráhyIC 520 · R 18981 · RE 26401 · ICE 5419:56 PM Brussels-Midi
15h29
1:25 PM Prague hlavní nádraží4 transfers
Wednesday, May 27
České dráhyIC 522 · R 5005 · ICE 1545 · rj 38312:20 AM Brussels-Midi
17h05
5:25 PM Prague hlavní nádraží3 transfers
České dráhyICE 11 · ICE 759 · rj 177
On time
6:23 AM Brussels-Midi
12h52
7:15 PM Prague-Holešovice		2 transfers
České dráhyICE 11 · ICE 621 · R 3569 · EC 359
On time
6:23 AM Brussels-Midi
11h58
6:21 PM Prague hlavní nádraží		3 transfers
České dráhyICE 11 · ICE 621 · R 3469 · R 3569
On time
6:23 AM Brussels-Midi
11h58
6:21 PM Prague hlavní nádraží		4 transfers
České dráhyICE 11 · ICE 621 · R 3469 · R 3569
On time
6:23 AM Brussels-Midi
11h58
6:21 PM Prague hlavní nádraží		4 transfers
České dráhyICE 11 · ICE 759 · rj 177
On time
6:23 AM Brussels-Midi
12h52
7:15 PM Prague-Holešovice		2 transfers
Deutsche BahnICE 11 · ICE 621 · 3469+alex-Länderbahn und Vogtlandbahn-GmbH359
On time
6:23 AM Brussels-Midi
11h58
6:21 PM Prague hlavní nádraží		3 transfers
České dráhyIC 505 · R 18921 · RE 26413 · ICE 5476:56 AM Brussels-Midi
12h19
7:15 PM Prague-Holešovice4 transfers
Deutsche BahnIC 505 · 18921 · 26413 · ICE 547
On time
6:56 AM Brussels-Midi
12h18
7:14 PM Prague-Holešovice		4 transfers
České dráhyICE 13 · ICE 625 · R 3573 · EC 361
On time
8:25 AM Brussels-Midi
11h56
8:21 PM Prague hlavní nádraží		3 transfers
Deutsche BahnICE 13 · ICE 625 · 3573+alex-Länderbahn und Vogtlandbahn-GmbH361
On time
8:25 AM Brussels-Midi
11h56
8:21 PM Prague hlavní nádraží		3 transfers
České dráhyICE 13 · ICE 1651 · rj 385
On time
8:25 AM Brussels-Midi
13h00
9:25 PM Prague hlavní nádraží		2 transfers
Deutsche BahnICE 13 · ICE 625 · 3473+alex-Länderbahn und Vogtlandbahn-GmbH361
On time
8:25 AM Brussels-Midi
11h56
8:21 PM Prague hlavní nádraží		3 transfers
České dráhyICE 13 · ICE 625 · R 3473 · R 3573
On time
8:25 AM Brussels-Midi
11h56
8:21 PM Prague hlavní nádraží		4 transfers
Deutsche BahnICE 13 · ICE 1651 · ECE 385
On time
8:25 AM Brussels-Midi
13h00
9:25 PM Prague hlavní nádraží		2 transfers
Deutsche BahnICE 13 · ICE 1651 · ECE 385
On time
8:25 AM Brussels-Midi
13h00
9:25 PM Prague hlavní nádraží		2 transfers
Deutsche BahnICE 13 · ICE 625 · 3473+alex-Länderbahn und Vogtlandbahn-GmbH361
On time
8:25 AM Brussels-Midi
11h56
8:21 PM Prague hlavní nádraží		3 transfers
České dráhyICE 13 · ICE 625 · R 3473 · R 3573
On time
8:25 AM Brussels-Midi
11h56
8:21 PM Prague hlavní nádraží		4 transfers
České dráhyICE 13 · ICE 1651 · rj 385
On time
8:25 AM Brussels-Midi
13h00
9:25 PM Prague hlavní nádraží		2 transfers
Deutsche BahnICE 13 · ICE 1651 · RJ 385
On time
8:25 AM Brussels-Midi
13h00
9:25 PM Prague hlavní nádraží		2 transfers
Deutsche BahnICE 13 · ICE 2461 · RJ 393
On time
8:25 AM Brussels-Midi
13h00
9:25 PM Prague hlavní nádraží		2 transfers
České dráhyICE 15 · ICE 1549 · rj 179
On time
10:25 AM Brussels-Midi
13h06
11:31 PM Prague hlavní nádraží		2 transfers
Deutsche BahnICE 15 · 28518 · ICE 629 · 3577
On time
10:25 AM Brussels-Midi
11h57
10:22 PM Prague hlavní nádraží		4 transfers
Deutsche BahnICE 15 · ICE 1549 · RJ 179
On time
10:25 AM Brussels-Midi
13h06
11:31 PM Prague hlavní nádraží		2 transfers
České dráhyICE 15 · RE 28518 · ICE 629 · R 3597
On time
10:25 AM Brussels-Midi
11h57
10:22 PM Prague hlavní nádraží		4 transfers
České dráhyICE 315 · ICE 611 · ICE 1655 · NJ 457
On time
12:25 PM Brussels-Midi
12h01
12:26 AM Prague hlavní nádraží		3 transfers
Deutsche BahnICE 17 · ICE 1657 · S1 · 280182:25 PM Brussels-Midi
17h45
8:10 AM Prague hlavní nádraží4 transfers
Deutsche BahnICE 17 · 28526 · ICE 727 · ICE 1657
On time
2:25 PM Brussels-Midi
17h45
8:10 AM Prague hlavní nádraží		6 transfers
Deutsche BahnICE 317 · ICE 590 · 16501 · S1
On time
4:22 PM Brussels-Midi
16h48
9:10 AM Prague hlavní nádraží		5 transfers
České dráhyNJ 469 · EC 334
On time
7:06 PM Brussels-Midi
20h33
3:39 PM Prague hlavní nádraží		1 transfer

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Brussels to Prague by train, bus, or flight

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Why should you book Brussels to Prague trains with Omio?

Deutsche Bahn as well as Alibus, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH, European Sleeper and more offer trains services from Brussels to Prague.
Omio is an official ticket reseller for all your travel options from Brussels to Prague.

Why book with Omio vs Deutsche Bahn?

  • Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of Alibus, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH or European Sleeper to find the best option for your trip from Brussels to Prague.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Brussels to Prague.

Why book with Omio over Trainline, Wanderu or Raileurope?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Alibus, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH or European Sleeper to find the best option for your trip from Brussels to Prague.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Brussels to Prague.

How far in advance should I book train tickets from Brussels to Prague?

The best time to book your train from Brussels to Prague is 91 days before departure. See how prices for trains change on the Brussels to Prague route.
Prices are for one-way tickets for one passenger from Brussels to Prague per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from Brussels to Prague.

Journey information

Overview: Train from Brussels to Prague

BelgiumBelgium
CzechiaCzechia
Icon of train

Trains from Brussels to Prague run on average 6 times per day, taking around 12h 50m. Cheap train tickets for this journey start at $13 (€11) if you book in advance.

The earliest train runs at 00:33, the last at 23:58. The fastest train covers the 445 miles (717 km) distance in 10h 50m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
445 miles (717 km)
Average train duration
12h 50m
Cheapest ticket price
$13 (€11)
Trains per day
6
Fastest train
10h 50m
First train
12:33 AM
Last train
11:58 PM
Cheapest Month
Jul
Cheapest Day
Mon
High Season
Oct - Dec
Low Season
Jan - Mar
Busiest Day
Sat
Least Busy Day
Sun
Best time to book
77 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Train companies: Deutsche Bahn, Alibus, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH, European Sleeper from Brussels to Prague trainsDeutsche Bahn, Alibus, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH, European Sleeper trains will get you between Brussels and Prague from $13 (€11). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Deutsche Bahn

About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Duration
14h 45m
Cheapest Price
$161 (€130)
Deutsche Bahn frequency
3 a day
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone
Learn more about Deutsche Bahn

Alibus

About
European Sleeper is a Belgian-Dutch train company launched in 2021, operating night train services between Germany and Belgium three times a week, with plans to expand to daily service and extend routes to cities such as Dresden and Prague. Passengers can choose from standard seats, couchettes, or sleeper cabins. Couchettes include free drinks and power outlets, while sleeper cabins offer power outlets and complimentary meals. All tickets are sold as Flex Night fares, which are non-exchangeable but can be canceled up to 48 hours before departure.
Luggage & cancellation policy
Average Duration
15h 29m
Cheapest Price
$99 (€80)
Alibus frequency
1 a day
Luggage included
1 piece of hand luggage and 2 pieces of hold luggage included in ticket price
Luggage storage
Luggage racks above seats and at end of carriages
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car serving breakfast, drinks and snacks available for purchase
Seat reservation
Seat or berth reservation mandatory and included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces available, accessible toilets, staff assistance
Pets
Small pets in carriers allowed for free, larger dogs require paid ticket
Quiet zone
Learn more about Alibus

alex-Länderbahn und Vogtlandbahn-GmbH

About
agilis is a railway company operating regional trains based in Regensburg in Bavaria since 2010. It operates in the German state of Bavaria connecting cities like Ulm, Ingolstadt, Regensburg and Plattling. They offer single tickets and comfortable trains with some popular routes covering Ulm to Regensburg, Neumarkt to Passau and Ingolstadt to Plattling.
Luggage & cancellation policy
alex-Länderbahn und Vogtlandbahn-GmbH frequency
1 a day
Luggage included
One piece of hand luggage and one larger piece included
Luggage storage
Overhead racks and designated luggage areas
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund for canceled services
Amenities on board the train
Wifi
Food sold onboard
Snack and beverage service available on some routes
Seat reservation
Seat reservations available for additional fee
Toilets
USB plugs
Accessibility
Wheelchair spaces available, assistance for boarding/alighting
Pets
Small pets in carriers travel free, larger dogs require ticket and muzzle
Quiet zone
Learn more about alex-Länderbahn und Vogtlandbahn-GmbH

České dráhy

About
Czech Railways (České dráhy, ČD) is the largest railway company in the Czech Republic, connecting major cities, small towns, and even international destinations across Europe. Its extensive fleet of modern trains ranges from comfortable regional services with A/C and onboard WiFi to high-speed trains offering dining cars, power outlets, and premium seating for long-distance journeys. Czech Railways combines affordability and convenience, making it a popular choice for travelers exploring the Czech Republic and beyond.
Luggage & cancellation policy
Average Duration
10h 50m
Cheapest Price
$13 (€11)
České dráhy frequency
6 a day
Luggage included
You can transport briefcases, laptops, rucksacks, trolley bags and suitcases on board at no charge.
Additional luggage
Items of luggage must not be so big or heavy that they cannot be carried by a single person, with a generous maximum size of 90 x 60 x 40 cm and a maximum weight of 50kg.
Luggage storage
Luggage can be stored above or below the seat, on the passenger's lap, or in special luggage racks in certain carriages.
Cancellation Policy
Tickets purchased online can be returned free of charge up to 15 minutes before the train's departure.
Refund
If a train is completely canceled, booking fees are refundable, and compensation may be due directly from the rail operator.
Pregnant on board
Being pregnant on board is allowed.
Unaccompagned minor
Automatic compensation for online ČD domestic tickets applies if the system registers a delay of more than 60 minutes at the destination and the ticket was checked by the conductor.
Amenities on board the train
Food sold onboard
A hearty breakfast is included in the ticket price for sleeper carriage services.
Seat reservation
Seat reservations are included with tickets and adjacent seats are booked wherever possible.
Accessibility
Czech Railways is continuously expanding its fleet of wheelchair-accessible carriages and offers assistance for passengers with limited mobility.
Pets
Small pets are allowed on board, but cannot be transported in 1st class, restaurant, or bistro cars.
Learn more about České dráhy

European Sleeper

Luggage & cancellation policy
Average Duration
12h 34m
Cheapest Price
$74 (€60)
European Sleeper frequency
1 a day

Complete guide to Prague

Things to do in Prague

Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.

  • Must visit

National Museum

Prague’s flagship museum on Wenceslas Square, with major natural history, history, and cultural collections in a monumental Neo-Renaissance building.

View on mapVisit website
  • Must visit

Jewish Museum in Prague

A major museum complex preserving Prague’s Jewish heritage through synagogues, ceremonial objects, archives, and cemetery access.

View on mapVisit website
  • Recommended

DOX Centre for Contemporary Art

A leading contemporary art venue in Holešovice known for ambitious exhibitions, design, and the striking Gulliver airship installation.

View on mapVisit website

Czech Koruna

Moderate by European standards. Beer, transit, and casual meals are affordable; central hotels cost more.

Average meal costs

Budget
CZK 150-250 for street food or a simple lunch.
Mid-range
CZK 300-600 per person at a mid-range restaurant.
Fine dining
CZK 1,000+ per person at upscale restaurants.
Coffee
CZK 55-85 for a cappuccino.

Tipping culture

Around 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. Not expected for counter service, but appreciated.

FAQs: Trains from Brussels to Prague

Find answers to the most common questions about traveling from Brussels to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

FAQs
Train ticket prices from Brussels to Prague can vary. The cheapest ticket starts at $13 (€11), while the average price is around $130 (€105).
The train from Brussels to Prague takes 10h 50m and runs 6 per day.
The distance by train from Brussels to Prague is 445 miles (717 km).
The first train from Brussels to Prague leaves at 12:33 AM.
The last train from Brussels to Prague leaves at 11:58 PM.
Yes, there is a direct train from Brussels to Prague. This service operates 0 times per day, provided by Alibus, European Sleeper.
Yes, there is a night train from Brussels to Prague.
The train station in Brussels that goes to Prague is Brussels-Midi, which connects to Prague hlavní nádraží.
The cheapest way to get from Brussels to Prague is by train, with a cost of around $13 (€11).
The train journey from Brussels to Prague is moderately scenic, featuring views of rolling hills, quaint villages, and lush forests, particularly as you travel through Germany's countryside.
A day trip from Brussels to Prague is not feasible as the journey takes 10h 50m. The distance between the two cities is 445 miles (717 km) and there are 4 train trips available per day.
In Prague, you can enjoy panoramic views from Petrin Hill and visit attractions like the Petrin Tower and Mirror Maze. Experience the vibrant nightlife in Vinohrady with its trendy bars and cafes, or take a boat cruise on the Vltava River for unique views of the city's landmarks. Delve into Czech history at the National Museum, and enjoy a classical music concert in one of the city's historic venues. Must-see sights include Prague Castle, Charles Bridge, Old Town Square with the Astronomical Clock, St. Vitus Cathedral, and the historic Jewish Quarter.
To fully experience Prague, 3 to 4 days are recommended, allowing time to explore key attractions like Prague Castle, Charles Bridge, Old Town Square, and the Jewish Quarter, as well as enjoy local cuisine and culture.
Yes, you can take the train from Brussels to Prague.
Since both Brussels and Prague are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Prague include Kutná Hora, Plzeň, Pardubice, Hradec Králové, Karlštejn.
We recommend using the flight as it is the most popular way to get from Brussels to Prague among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in Czechia is the Czech koruna (CZK). While many places accept card payments, cash is still widely used, especially in smaller shops and markets, so travelers should carry some cash but can also use cards conveniently in most urban areas.
In Prague, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, Old Town Square, and major tourist sites. Common scams include overpriced taxi rides without meters, street vendors selling fake tickets or souvenirs, and distraction techniques used by thieves. It's advisable to use official taxis or ride-hailing apps, keep valuables secure, and be wary of strangers offering unsolicited help.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular train stations

Popular train stations from Brussels to Prague

Brussels
Prague
The major train station for departures in Brussels is Bruxelles-Midi. Find all the information you need to know about services, amenities and connections at Bruxelles-Midi for your trip from Brussels to Prague.
Bruxelles-MidiWifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
address
Address
47B Avenue Fonsny, 1060 Brussels, Belgium
ticketOfficeHours
Ticket Office Hours
  • Mon - Sun: 05:45 - 21:30
Wifi
Wifi
  • Wi-Fi is available for a fee.
Lockers
Lockers
  • Baggage storage facility is located across from the Thalys business lounge.
Dining
Dining
  • Pullman Hotel Bar
  • Quick Gare du Midi
  • Subway
  • EXKi Zuid
  • Starbucks
  • Häagen-Dazs
  • Sbarro
  • The Coffee Club
  • The Belgian Chocolate House
  • PAUL
  • & many more
Accessibility
Accessibility
  • Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Hotel
Hotel
  • Les Lofts De Styliste
  • Park Inn by Radisson Brussels Midi
  • Pullman Brussels Centre Midi
Information Desk
Information Desk
  • Located in the main concourse and next to the international platforms.
Bruxelles-CentralWifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
address
Address
Carr de l'Europe, 1000 Bruxelles, Belgium
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • Mon - Sun: 06:15 - 22:00
Wifi
Wifi
  • Free Wi-Fi available in Starbucks.
Lockers
Lockers
  • Luggage lockers are located on Level 0 near Platforms 1 and 2.
Dining
Dining
  • Starbucks
  • Brasserie 28 Brewery
  • Panos
  • Delitraiteur Eat & Go
Accessibility
Accessibility
  • Station has a wide range of facilities for passengers with limited mobility: elevators and escalators to platforms, wheelchair lifts and mobile ramps, barrier-free toilets and accessible parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Hotel
Hotel
  • Hilton Brussels Grand Palace
  • Hotel NH Brussels Carrefour de l'Europe
  • Hôtel The Moon
Ticket Office
Ticket Office
  • Mon - Sun: 06:15 - 22:00
Information Desk
Information Desk
  • Travel Center / information desk is located on the left side from the main entrance.
Public transit options for Bruxelles-Central
  • Metro lines: 1, 5
  • Train lines: IC, Intercity Direct 9200, RER (S1, S2, S3, S6, S8, S10)
Bruxelles-CongresParkingDiningATMTaxisAccessibilityWCHotelBike ParkingBike Rental
Amenities at train station
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Bike ParkingBike Parking
Bike RentalBike Rental
information
address
Address
1050 Bruxelles, Belgium

More options for your journey from Brussels to Prague

Here are some other resources that might have the information you need

Return journeys for trains from Prague to Brussels
Buses from Brussels to Prague
Flights from Brussels to Prague
Compare all journeys between Brussels and Prague
Tickets and more information for trains to Brussels
Tickets and more information for trains to Prague

Most popular trains to and from Prague and Brussels

Train Brussels - Bouillon
Train Brussels - Landgraaf
Train Brussels - Saint-Ghislain
Train Ehingen (Donau) - Prague
Train Brussels - Lichtervelde
Train Hradec Králové - Prague
Train Rybnik - Prague
Train Pula - Prague
Train Spišská Nová Ves - Prague
Train Neumarkt am Wallersee - Prague
Train Brussels - Estrées-Deniécourt
Train Brussels - Nieuwpoort
Train Brussels - Kingersheim
Train Apolda - Prague
Train Brussels - Billund Airport
Train Vilshofen - Prague
Train Oswiecim - Prague
Train Liptovský Mikuláš - Prague
Train Brussels - Ciney
Train Mühlhausen (Thür) - Prague
Train Brussels - Enghien
Train Brussels - Kontich
Train Brussels - Wevelgem
Train Brussels - Brasschaat
Train Brussels - De Haan
Train Kulmbach - Prague
Train Maintal - Prague
Train Piestany - Prague
Train Brussels - Brake
Train Brussels - Karlstadt am Main
Train Brussels - Monschau
Train Brussels - Ninove
Train Zlín - Prague
Train Bolesławiec - Prague
Train Schärding - Prague
Train Brussels - Virton
Train Brussels - Merchtem
Train Cadca - Prague
Train Altenmarkt im Pongau - Prague
Train Brussels - Normandy
Train Trnava - Prague
Train Amberg - Prague
Train Brussels - Stendal
Train Ružomberok - Prague
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