- Must visit
National Museum
Prague’s flagship museum on Wenceslas Square, with major natural history, history, and cultural collections in a monumental Neo-Renaissance building.
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The cheapest and fastest buses from Pisa to Prague
Showing times and prices for Jun 04
Cheapest price
$88
Average price
$107
Fastest journey
16 h 15 m
Average duration
18 h 1 m
Buses per day
12
Distance
771 km
Cheap tickets
The best way to find a cheap bus ticket from Pisa to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Prague will cost around $107 if you buy it on the day, but the cheapest tickets can be found for only $88.
Fast buses
Of the 12 buses that leave Pisa for Prague on Thu, Jun 04, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jun 04 the direct buses cover the 771 km distance in an average of 18 h 1 m but if you time it right, some buses will get you there in just 16 h 15 m .
On Thu, Jun 04 the slowest buses will take 19 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus5:10 PM16h15Pisa, Via delle Fiamme Gialle (Park Pietrasantina)9:25 AMPraha, ÚAN Florenc$881One-way0 transfers- FlixBus · FlixBus · FlixBus10:00 PM19h45Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:45 PMPraha, ÚAN Florenc$941One-way2 transfers
- FlixBus · FlixBus · FlixBus10:00 PM19h30Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:30 PMPrague, Central Train Station$941One-way2 transfers
- FlixBus · FlixBus · FlixBus9:40 AM21h20Pisa, Via delle Fiamme Gialle (Park Pietrasantina)7:00 AMPrague, Central Train Station$951One-way2 transfers
- FlixBus · FlixBus · FlixBus9:40 AM20h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:45 AMPraha, ÚAN Florenc$1011One-way2 transfers
- FlixBus5:10 PM16h15Pisa, Via delle Fiamme Gialle (Park Pietrasantina)9:25 AMPraha, ÚAN Florenc$881One-way0 transfers
- FlixBus · FlixBus5:10 PM17h25Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:35 AMPrague, Central Train Station$1021One-way1 transfer
- FlixBus · FlixBus · FlixBus5:10 PM18h20Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:30 AMPraha, Zličín$1011One-way2 transfers
- FlixBus · FlixBus · FlixBus5:10 PM18h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:45 AMPraha, Na Knížecí$1111One-way2 transfers
- FlixBus · FlixBus · FlixBus10:00 PM19h30Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:30 PMPrague, Central Train Station$941One-way2 transfers
Travel Information
Compare train, bus, and flight for Pisa to Prague
Omio recommends booking the flight as it is the most popular option from Pisa to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $63. For those with little time consider booking a flight which can get you there in 1h 52m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.8 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of $63, and a train costs an average of $242.
Distance: 479 miles (771 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$95 Average price Cheapest | $216 Average price | $262 Average price | $289 Average price (fuel + tolls) |
17h 16m Average total duration 16h 46m Onboard + 30m Additional time* | 4h 52m Average total duration Fastest 1h 52m Onboard + 3h 0m Additional time* | 20h 33m Average total duration 20h 3m Onboard + 30m Additional time* | 11h 54m Average total duration (door-to-door) |
0.8 - 1.9kg CO2 emissions Lowest | 2.3 - 4.6kg CO2 emissions | - CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Pisa to Prague is a bus with an average price of $95 (€77).
This is compared to other travel options from Pisa to Prague:
A bus is $121 (€97) less than a flight for this route with tickets for a flight from Pisa to Prague costing on average $216 (€175).
A bus is $167 (€135) less than a train for this route with tickets for a train from Pisa to Prague costing on average $262 (€212).
The fastest way to travel from Pisa to Prague is by flight with an average journey time of 1h 52m.
Other travel options to Prague take longer:
Bus takes on average 16h 46m.
Train takes on average 20h 3m.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Prague including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Pisa to Prague among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $95 (€77) compared to roughly $289 (€234) in fuel and tolls — a saving of about $194 (€156). The journey takes 16h 46m versus 11h 54m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Pisa to Prague Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:45AM | Arrival Time 03:15AM | Duration 22h30 | Departure days Fri | Cheapest price $107 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 03:15AM | Duration 20h50 | Departure days Mon, Sun | Cheapest price $155 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 03:15AM | Duration 20h00 | Departure days Everyday | Cheapest price $77 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 07:00AM | Duration 21h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $82 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 12:10PM | Duration 19h00 | Departure days Everyday | Cheapest price $72 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 02:35PM | Duration 20h25 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $117 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 05:45PM | Duration 19h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $82 |
Live departures
Pisa to Prague bus times
The table below shows live departures for Pisa to Prague buses for today, Wednesday, June 3. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 24h25 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 26h00 | 7:10 PM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h00 | 12:10 PM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h15 | 12:25 PM Praha, ÚAN Florenc | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 26h50 | 8:00 PM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 6:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h25 | 2:35 PM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 6:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h35 | 2:45 PM Praha, ÚAN Florenc | 2 transfers | |
| Thursday, June 4 | |||||
| FlixBus · FlixBus · FlixBus | 7:15 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h00 | 3:15 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 9:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 21h20 | 7:00 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 9:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h05 | 5:45 AM Praha, ÚAN Florenc | 2 transfers | |
Find all the dates and times for this journey
Compare prices and tickets Pisa to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Pisa to Prague buses with Omio?
FlixBus operates all buses services from Pisa to Prague.
Omio is an official ticket reseller for all your travel options from Pisa to Prague.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Prague.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Prague.
Journey information
Overview: Bus from Pisa to Prague
Italy
Czechia
Buses from Pisa to Prague run on average 12 times per day, taking around 16h 46m. Cheap bus tickets for this journey start at $63 (€51) but you can travel from only $28 (€23) by flight.
There are 1 buses per day. The earliest bus runs at 01:00, the last at 23:50. The fastest bus covers the 479 miles (771 km) distance in 16h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $28 (€23)
Distance 479 miles (771 km) |
Average bus duration 16h 46m |
Cheapest ticket price $63 (€51) |
Buses per day 12 |
Direct buses 1 |
Fastest bus 16h 5m |
First bus 1:00 AM |
Last bus 11:50 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Wed |
Least Busy Day Sat |
Best time to book 42 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $28 (€23)
Bus providers: FlixBus from Pisa to PragueYou can travel by bus between Pisa to Prague with FlixBus for as low as $28 (€23). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
16h 5m
Cheapest Price
$63 (€51)
FlixBus frequency
12 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Prague
Things to do in Prague
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
- Must visit
Jewish Museum in Prague
A major museum complex preserving Prague’s Jewish heritage through synagogues, ceremonial objects, archives, and cemetery access.
- Recommended
DOX Centre for Contemporary Art
A leading contemporary art venue in Holešovice known for ambitious exhibitions, design, and the striking Gulliver airship installation.
- Must visit
Old Town Square
Prague’s historic central square, surrounded by major landmarks and lively at all hours, making it an essential first stop.
- Must visit
Malá Strana
A picturesque district of Baroque streets, embassies, gardens, and hidden corners beneath Prague Castle, ideal for walking and photography.
- Recommended
Wenceslas Square
A broad boulevard-like square central to modern Czech history, shopping, and city life, anchored by the National Museum.
Svíčková Na Smetaně
Marinated beef sirloin with creamy root-vegetable sauce, bread dumplings, cranberry sauce, and whipped cream. One of the most classic Czech celebratory dishes.
Vepřo Knedlo Zelo
Roast pork served with bread dumplings and braised cabbage. A cornerstone of traditional Czech home cooking and pub menus.
Guláš
Czech-style goulash, usually beef, slower-cooked and less soupy than the Hungarian version, commonly served with dumplings. A staple in Prague pubs.
Field
Michelin-starred restaurant offering contemporary Czech fine dining with seasonal ingredients and a sophisticated atmosphere.
Mincovna
Well-known restaurant near Old Town Square offering refined Czech classics in a polished but approachable setting.
Café Savoy
Elegant grand cafe and restaurant known for excellent breakfasts, pastries, and upscale Czech and Central European dishes.
Czech Koruna
Moderate by European standards. Beer, transit, and casual meals are affordable; central hotels cost more.
Average meal costs
- Budget
- CZK 150-250 for street food or a simple lunch.
- Mid-range
- CZK 300-600 per person at a mid-range restaurant.
- Fine dining
- CZK 1,000+ per person at upscale restaurants.
- Coffee
- CZK 55-85 for a cappuccino.
Tipping culture
Around 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. Not expected for counter service, but appreciated.
PID Lítačka
Get the appOfficial public transport app
Prices
- Single ticket
- 30 CZK
- Day pass
- 120 CZK
To the city center
Prague Main Railway Station, Prague -> Old Town Square, Prague
- Distance
- 2 km
- Travel time
- 10 min
- Validate paper tickets before first use; app tickets must usually be activated before boarding.
- Card payment is available in Prague Metro stations and in many trams and buses, but carry a backup payment method.
FAQs: Bus from Pisa to Prague
Find answers to the most common questions about traveling from Pisa to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Pisa to Prague can start from as little as $63 (€51) when you book in advance. The average bus ticket price for Pisa to Prague is $95 (€77) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Pisa to Prague is 16h 5m to travel the 479 miles (771 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Pisa to Prague leaves at 1:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Pisa to Prague leaves at 11:50 PM.
Yes, there are 1 direct buses a day from Pisa to Prague with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Pisa to Prague, you can count on FlixBus for the best way to get you to Prague. You can also check all possible bus companies who offer a service between Pisa and Prague and compare the amenities they offer before buying a bus ticket.
When departing from Pisa , you have various bus station options to start your journey from including Pisa, Via delle Fiamme Gialle (Park Pietrasantina), Pisa, Aeroporto Parcheggio Aurelia . When arriving in Prague , you can end your journey in bus stations like Prague, Central Train Station, Praha, ÚAN Florenc, Praha, Na Knížecí, Praha, Černý Most, Praha, Zličín, Praha, Roztyly, Praha, M. Horákové (Hradčanská), Praha, Letiště Václava Havla .Passengers board the bus most frequently from Pisa, Via delle Fiamme Gialle (Park Pietrasantina), which is located around 0 away from the city centre, and they get off the bus at Prague, Central Train Station, located 1 away from the city centre.
A trip to Prague from Pisa is worth doing but not as a day trip with a journey time of 16h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Pisa to Prague is July.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Prague including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Pisa to Prague:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Pisa to Prague for bus company FlixBus.
Some of the most interesting sights to explore in Prague are:
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
The best things to do in Prague include:
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
Whether you can cancel your bus ticket from Pisa to Prague depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Pisa to Prague.
Yes, the following luggage options are included when booking a bus ticket from Pisa to Prague:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Prague:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Pisa to Prague. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Pisa to Prague with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Pisa to Prague with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Pisa to Prague with the following bus company: FlixBus.
Since both Pisa and Prague are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Pisa to Prague among Omio's users.
The currency used in Czechia is the Czech koruna (CZK). While many places accept card payments, cash is still widely used, especially in smaller shops and markets, so travelers should carry some cash but can also use cards conveniently in most urban areas.
In Prague, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, Old Town Square, and major tourist sites. Common scams include overpriced taxi rides without meters, street vendors selling fake tickets or souvenirs, and distraction techniques used by thieves. It's advisable to use official taxis or ride-hailing apps, keep valuables secure, and be wary of strangers offering unsolicited help.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Pisa to Prague
Pisa
Prague
The major bus station for departures in Pisa is Pisa, Via delle Fiamme Gialle (Park Pietrasantina). Find all the information you need to know about services, amenities and connections at Pisa, Via delle Fiamme Gialle (Park Pietrasantina) for your trip from Pisa to Prague.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
information
Pisa, Aeroporto Parcheggio Aurelia
information
The major bus station for arrivals in Prague is Praha, Hlavní Nádraží. Find all the information you need to know about services, amenities and connections at Praha, Hlavní Nádraží for your trip to Prague from Pisa.
Amenities at bus station
Wifi
Parking
Dining
ATM
Taxis
Accessibility
WC
Ticket Officeinformation
Ticket Office Hours
- 00:00-23:59
Distance to city center
1 km
Car connection
WilsonovaWifi
- Free Wi-Fi
Dining
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, Hlavní Nádraží
- Bus: 135, 175, 207 Metro: C Train: All major s
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 kmCar connection
KřižíkovaWifi
- Free Wi-Fi
Dining
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, ÚAN Florenc
- Bus: 133, 135, 175, 207 Metro: B, C
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCinformation
Distance to city center
2 kmCar connection
OstrovskéhoWifi
- Free Wi-Fi
Dining
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, Na Knížecí
- Bus: 137, 176, 191 Metro: B
Most popular bus connections from Pisa
More options for your journey from Pisa to Prague
Here are some other resources that might have the information you need
Most popular buses to and from Prague and Pisa
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