Pisa to Prague bus with FlixBus

Fri, Sep 04
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The cheapest and fastest buses from Pisa to Prague

Showing times, prices and bookable tickets for Sep 04

Cheapest price on Sep 04

$83

Average ticket price on Sep 04

$112

Fastest journey on Sep 04

16 h 15 m

Average journey duration on Sep 04

18 h 13 m

Buses on Sep 04

13

Distance

771 km

Cheap tickets

The best way to find a cheap bus ticket from Pisa to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Pisa to Prague will cost around $112 if you buy it on the day, but the cheapest tickets can be found for only $83.

Fast buses

On Fri, Sep 04, we found 13 buses from Pisa to Prague, including 1 direct services.

On Fri, Sep 04 the direct buses cover the 771 km distance in an average of 18 h 13 m but if you time it right, some buses will get you there in just 16 h 15 m .

On Fri, Sep 04 the slowest buses will take 19 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBusFlixBus
    5:10 PM16h15
    Pisa (Pisamover via San Giusto/Aurelia)
    9:25 AMPraha, ÚAN Florenc
    $831One-way
    0 transfers
  • FlixBusFlixBus · FlixBus · FlixBus
    5:10 PM18h20
    Pisa (Pisamover via San Giusto/Aurelia)
    11:30 AMPraha, Zličín
    $981One-way
    2 transfers
  • FlixBusFlixBus · FlixBus
    5:10 PM17h25
    Pisa (Pisamover via San Giusto/Aurelia)
    10:35 AMPrague, Central Train Station
    $991One-way
    1 transfer
  • FlixBusFlixBus · FlixBus · FlixBus
    9:40 AM20h05
    Pisa (Pisamover via San Giusto/Aurelia)
    5:45 AMPraha, ÚAN Florenc
    $1021One-way
    2 transfers
  • FlixBusFlixBus · FlixBus · FlixBus
    10:00 PM19h30
    Pisa (Pisamover via San Giusto/Aurelia)
    5:30 PMPrague, Central Train Station
    $1041One-way
    2 transfers

Travel Information

Compare train, bus, and flight for Pisa to Prague

Omio recommends booking the flight as it is the most popular option from Pisa to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $102 For those with little time, consider booking a flight, which has an average total journey time of 4h 11m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.8 - 1.9kg. Average ticket prices depend on the travel mode: a bus costs an average of $102, while a train costs an average of $262.

Distance: 479 miles (771 km)

Compare bus with

Bus
Most popular
Flight
Train
Driving

$102

Average price

Cheapest

$199

Average price

$262

Average price

$291

Average price

(fuel + tolls)

17h 8m

Average total duration

16h 38m

Onboard

+

30m

Additional time*

4h 11m

Average total duration

Fastest

2h 11m

Onboard

+

2h 0m

Additional time*

20h 33m

Average total duration

20h 3m

Onboard

+

30m

Additional time*

11h 54m

Average total duration

(door-to-door)

0.8 - 1.9kg

CO2 emissions

Lowest

2.3 - 4.6kg

CO2 emissions

-

CO2 emissions

-

CO2 emissions

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Pisa to Prague is a bus with an average price of $102 (€83).

This is compared to other travel options from Pisa to Prague:

A bus is $97 (€79) less than a flight for this route with tickets for a flight from Pisa to Prague costing on average $199 (€161).

A bus is $160 (€130) less than a train for this route with tickets for a train from Pisa to Prague costing on average $262 (€212).

The fastest way to travel from Pisa to Prague is by flight with an average journey time of 2h 11m.

Other travel options to Prague take longer:

Bus takes on average 16h 38m.

Train takes on average 20h 3m.

It's helpful to compare your options as there are 3 ways to travel between Pisa and Prague including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Pisa to Prague among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $102 (€83) compared to roughly $291 (€236) in fuel and tolls — a saving of about $190 (€154). The journey takes 16h 38m versus 11h 54m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Direct services are operated by FlixBus.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Pisa to Prague Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
06:25AM
Arrival Time
03:15AM
Duration
20h50
Departure days
Mon, Fri, Sat
Cheapest price
$125
Operator
FlixBus
Departure Time
07:15AM
Arrival Time
03:15AM
Duration
20h00
Departure days
Tue, Wed, Thu, Fri, Sat, Sun
Cheapest price
$108
Operator
FlixBus
Departure Time
09:40AM
Arrival Time
05:45AM
Duration
20h05
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$91
Operator
FlixBus
Departure Time
05:10PM
Arrival Time
09:25AM
Duration
16h15
Departure days
Everyday
Cheapest price
$80
Operator
FlixBus
Departure Time
06:10PM
Arrival Time
02:35PM
Duration
20h25
Departure days
Wed, Thu, Fri, Sat, Sun
Cheapest price
$104
Operator
FlixBus
Departure Time
10:00PM
Arrival Time
05:30PM
Duration
19h30
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$94

Live departures

Pisa to Prague bus times

The table below shows live departures for Pisa to Prague buses for today, Thursday, September 3. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus · FlixBus · FlixBus7:15 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
20h00
3:15 AM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus · FlixBus9:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
21h20
7:00 AM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus · FlixBus9:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
20h05
5:45 AM Praha, ÚAN Florenc2 transfers
FlixBusFlixBus5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
16h15
9:25 AM Praha, ÚAN Florenc0 transfersDirect
FlixBusFlixBus · FlixBus5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
17h25
10:35 AM Prague, Central Train Station1 transfer
FlixBusFlixBus · FlixBus · FlixBus5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
23h00
4:10 PM Praha, Černý Most2 transfers
FlixBusFlixBus · FlixBus · FlixBus5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
18h35
11:45 AM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus · FlixBus5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
18h20
11:30 AM Praha, Zličín2 transfers
FlixBusFlixBus · FlixBus · FlixBus6:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
20h25
2:35 PM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus · FlixBus10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
22h20
8:20 PM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus · FlixBus10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
19h45
5:45 PM Praha, ÚAN Florenc2 transfers
FlixBusFlixBus · FlixBus · FlixBus10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
19h30
5:30 PM Prague, Central Train Station2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Pisa to Prague by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
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Sep 24

Why should you book Pisa to Prague buses with Omio?

FlixBus operates all buses services from Pisa to Prague.
Omio is an official ticket reseller for all your travel options from Pisa to Prague.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Prague.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Prague.

Journey information

Overview: Bus from Pisa to Prague

ItalyItaly
CzechiaCzechia
Icon of bus

Buses from Pisa to Prague run on average 11 times per day, taking around 16h 38m. Cheap bus tickets for this journey start at $72 (€58) but you can travel from only $23 (€19) by flight.

There are 1 buses per day. The earliest bus runs at 01:00, the last at 23:50. The fastest bus covers the 479 miles (771 km) distance in 16h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $23 (€19)
Distance
479 miles (771 km)
Average bus duration
16h 38m
Cheapest ticket price
$72 (€58)
Buses per day
11
Direct buses
1
Fastest bus
16h 5m
First bus
1:00 AM
Last bus
11:50 PM
Cheapest Month
Jul
Cheapest Day
Mon
High Season
Oct - Dec
Low Season
Jan - Mar
Busiest Day
Wed
Least Busy Day
Sun
Best time to book
28 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $23 (€19)

Bus providers: FlixBus from Pisa to PragueYou can travel by bus between Pisa to Prague with FlixBus for as low as $23 (€19). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
16h 5m
Cheapest FlixBus Price
$72 (€58)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Complete guide to Prague

Things to do in Prague

Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.

  • Must visit

National Museum

Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.

  • Must visit

Jewish Museum in Prague

Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.

  • Recommended

National Gallery Prague – Schwarzenberg Palace

Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.

Czech koruna (Kč)

Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.

Average meal costs

Budget
Kč150-Kč250 for fast food or street food.
Mid-range
Kč300-Kč600 per person for a meal.
Fine dining
Kč1,200+ per person for upscale restaurants.
Coffee
Kč55-Kč85 for cappuccino.

Tipping culture

Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.

FAQs: Bus from Pisa to Prague

Find answers to the most common questions about traveling from Pisa to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Pisa to Prague can start from as little as $72 (€58) when you book in advance. The average bus ticket price for Pisa to Prague is $102 (€83) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Pisa to Prague is 16h 5m to travel the 479 miles (771 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Pisa to Prague leaves at 1:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Pisa to Prague leaves at 11:50 PM.
Yes, there are 1 direct buses a day from Pisa to Prague with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Pisa to Prague, you can count on FlixBus for the best way to get you to Prague. You can also check all possible bus companies who offer a service between Pisa and Prague and compare the amenities they offer before buying a bus ticket.
When departing from Pisa , you have various bus station options to start your journey from including Pisa, Via delle Fiamme Gialle (Park Pietrasantina), Pisa (Pisamover via San Giusto/Aurelia) . When arriving in Prague , you can end your journey in bus stations like Prague, Central Train Station, Praha, ÚAN Florenc, Praha, Na Knížecí, Praha, Černý Most, Praha, Zličín, Praha, Roztyly, Praha, M. Horákové (Hradčanská), Praha, Letiště Václava Havla .Passengers board the bus most frequently from Pisa, Via delle Fiamme Gialle (Park Pietrasantina), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Prague, Central Train Station, located 1 away from the city centre.
A trip to Prague from Pisa is worth doing but not as a day trip with a journey time of 16h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Pisa to Prague is July.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Prague including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Pisa to Prague:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Pisa to Prague for bus company FlixBus.
Some of the most interesting sights to explore in Prague are:
  • Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
  • Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
  • Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
  • St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
  • The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
The best things to do in Prague include:
  • Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
  • Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
  • Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
  • Visit the National Museum to delve into Czech history and culture
  • Enjoy a classical music concert in one of Prague's historic churches or concert halls.
Whether you can cancel your bus ticket from Pisa to Prague depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Pisa to Prague.
Yes, the following luggage options are included when booking a bus ticket from Pisa to Prague:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Prague:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Pisa to Prague. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Pisa to Prague with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Pisa to Prague with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Pisa to Prague with the following bus company: FlixBus.
Since both Pisa and Prague are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Pisa to Prague among Omio's users.
The currency used in Czechia is the Czech koruna (CZK). While many places accept card payments, cash is still widely used, especially in smaller shops and markets, so travelers should carry some cash but can also use cards conveniently in most urban areas.
In Prague, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, Old Town Square, and major tourist sites. Common scams include overpriced taxi rides without meters, street vendors selling fake tickets or souvenirs, and distraction techniques used by thieves. It's advisable to use official taxis or ride-hailing apps, keep valuables secure, and be wary of strangers offering unsolicited help.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Pisa to Prague

Most Pisa to Prague buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Pisa and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Pisa
Arrival bus stations in Prague

Which Pisa station do buses to Prague leave from?

Buses from Pisa to Prague leave from Pisa, Via delle Fiamme Gialle (Park Pietrasantina). The station is 1 miles (2 km) from Pisa city centre at Pisa Pietrasantina Parking, 56123 Pisa PI, Italy.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)Pisa Pietrasantina Parking, 56123 Pisa PI, ItalyWifiParkingATMTaxisAccessibilityWCShowerTicket OfficeBike ParkingBike Rental
City-centre transport

Getting to Pisa, Via delle Fiamme Gialle (Park Pietrasantina) from Pisa city centre

Pisa, Via delle Fiamme Gialle (Park Pietrasantina) is 1 km from Pisa city centre. Public transport options include:

Bus21, E24, 1+ · 12m · $1 · every ~10 min
1+, 21 · 14m · $1 · every ~9 min
1+ · 24m · $2 · every ~9 min
21 · 30m · $2

Pisa, Via delle Fiamme Gialle (Park Pietrasantina) bus station facilities and services

Pisa, Via delle Fiamme Gialle (Park Pietrasantina) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, Ticket Office, Bike Parking, and Bike Rental.

Wi-Fi and ATMs

Wi-Fi is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina). ATMs are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).

Tickets and information

Ticket office support is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).

Parking, taxis and toilets

Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Parking, Taxis, WC.

Bike and car services

Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Bike Parking, Bike Rental.

Accessibility

Accessibility facilities are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): The station is accessible for people with reduced mobility.

Pisa (Pisamover via San Giusto/Aurelia)Via S. Giusto, 56121 Pisa PI, ItalyWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Pisa (Pisamover via San Giusto/Aurelia) from Pisa city centre

Pisa (Pisamover via San Giusto/Aurelia) is 1 km from Pisa city centre. Public transport options include:

Bus15 · 5m · $1 · every ~3 min
15 · 7m · $1 · every ~3 min
15 · 9m · $1 · every ~3 min

Pisa (Pisamover via San Giusto/Aurelia) bus station facilities and services

Pisa (Pisamover via San Giusto/Aurelia) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Pisa (Pisamover via San Giusto/Aurelia). ATMs are available at Pisa (Pisamover via San Giusto/Aurelia).

Tickets and information

Ticket office support is available at Pisa (Pisamover via San Giusto/Aurelia).

Parking, taxis and toilets

Available at Pisa (Pisamover via San Giusto/Aurelia): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Pisa (Pisamover via San Giusto/Aurelia): Wheelchair accessible with assistance.

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