The cheapest and fastest buses from Pisa to Prague
Cheapest price
$122
Average price
$163
Fastest journey
19 h 25 m
Average duration
19 h 53 m
Buses per day
16
Distance
771 km
The best way to find a cheap bus ticket from Pisa to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Prague will cost around $163 if you buy it on the day, but the cheapest tickets can be found for only $122.
It's difficult to get from Pisa to Prague without transferring at least 2 times.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBusTravel Information
Compare bus, train, and flight for Pisa to Prague
Omio recommends booking the flight as it is the most popular option from Pisa to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €51. For those with little time consider booking a flight which can get you there in 2h 26m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.8 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of €51, and a flight costs an average of €25.
Distance: 479 miles (771 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€95 Average price Cheapest | €273 Average price | €213 Average price |
17h 17m Average total duration 16h 47m Onboard + 30m Additional time* | 5h 26m Average total duration Fastest 2h 26m Onboard + 3h 0m Additional time* | 20h 44m Average total duration 20h 14m Onboard + 30m Additional time* |
0.8 - 1.9kg CO2 emissions Lowest | 2.3 - 4.6kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Pisa to Prague Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:50AM | Arrival Time 03:15AM | Duration 22h25 | Departure days Fri | Cheapest price $166 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 06:00AM | Duration 23h35 | Departure days Thu, Fri | Cheapest price $111 |
Operator FlixBus | Departure Time 07:10AM | Arrival Time 05:45AM | Duration 22h35 | Departure days Thu, Fri, Sat | Cheapest price $113 |
Operator FlixBus | Departure Time 11:30AM | Arrival Time 08:15AM | Duration 20h45 | Departure days Thu, Fri, Sat | Cheapest price $117 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 11:30AM | Duration 21h50 | Departure days Thu, Fri | Cheapest price $143 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 09:25AM | Duration 16h40 | Departure days Thu, Fri, Sat | Cheapest price $104 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 03:20PM | Duration 21h05 | Departure days Thu, Fri, Sat | Cheapest price $112 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 08:20PM | Duration 22h20 | Departure days Thu, Fri, Sat | Cheapest price $112 |
Live departures
Pisa to Prague bus times
The table below shows live departures for Pisa to Prague buses for today, Thursday, December 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 5:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h50 | 2:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:10 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 22h35 | 4:45 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:10 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 22h50 | 5:00 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:30 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 23h05 | 9:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:40 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 21h50 | 10:30 AM Praha, Zličín | 2 transfers | |
FlixBus | 3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h40 | 8:25 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 23h25 | 3:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus | 3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h25 | 11:10 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:15 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 21h05 | 2:20 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h45 | 4:45 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h30 | 4:30 PM Prague, Central Train Station | 2 transfers | |
| Friday, December 5 | |||||
FlixBus · FlixBus · FlixBus | 3:50 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 22h25 | 2:15 AM Prague, Central Train Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Prague by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 05
Dec 06
Dec 07
Dec 08
Dec 09
Dec 10
Dec 11
Journey information
Overview: Bus from Pisa to Prague
Buses from Pisa to Prague run on average 12 times per day, taking around 16h 47m. Cheap bus tickets for this journey start at $63 (€51) but you can travel from only $31 (€25) by flight.
There are 1 buses per day. The earliest bus runs at 01:00, the last at 23:50. The fastest bus covers the 479 miles (771 km) distance in 16h 40m.
Distance 479 miles (771 km) |
Average bus duration 16h 47m |
Cheapest ticket price $63 (€51) |
Buses per day 12 |
Direct buses 1 |
Fastest bus 16h 40m |
First bus 01:00 |
Last bus 23:50 |
Bus providers: FlixBus from Pisa to PragueYou can travel by bus between Pisa to Prague with FlixBus for as low as $31 (€25). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Pisa to Prague
Find answers to the most common questions about traveling from Pisa to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Pisa to Prague, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Pisa to Prague
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
Most popular bus connections from Pisa
More options for your journey from Pisa to Prague
Here are some other resources that might have the information you need
