PisaPrague
Mon, Jul 20, 1 adult
Mon, Jul 20
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Mon, Jul 20
+ Add return

FlixBus
05:10PM18h35m11:45AM
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
Praha, Na Knížecí
$1581One-way
FlixBus
05:10PM18h20m11:30AM
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
Praha, Zličín
$1801One-way
FlixBus
05:10PM17h25m10:35AM
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
Prague, Central Train Station
$1831One-way
Fastest
FlixBus
05:10PM16h15m09:25AM
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
Praha, ÚAN Florenc
$1451One-way
2nd cheapest
FlixBus
05:10PM23h0m04:10PM
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
Praha, Černý Most
$1671One-way
FlixBus
06:10PM20h25m02:35PM
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
Prague, Central Train Station
$1381One-way
Cheapest, 2nd Fastest
FlixBus
10:00PM19h30m05:30PM
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
Prague, Central Train Station
$1311One-way
Cheapest
FlixBus
10:00PM19h45m05:45PM
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
Praha, ÚAN Florenc
$1311One-way
FlixBus
10:00PM22h20m08:20PM
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
Praha, Na Knížecí
$1941One-way

The cheapest and fastest busesfrom Pisa to PragueShowing times and prices for Jul 19

Cheapest price

$131

Average price

$158

Fastest journey

16h 15m

Average duration

19h 31m

Buses per day

9

Distance

301 km

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Prices include taxes and may change depending on availability. Any additional fees can be reviewed before payment. The total price will be finalized once the purchase is completed.

Pisa to Prague bus with FlixBus

Travel Information

Compare train, bus, and flight for Pisa to Prague

Omio recommends booking the flight as it is the most popular option from Pisa to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $62. For those with little time consider booking a flight which can get you there in 1h 52m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.8 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of $62, and a train costs an average of $239.

Distance: 479 miles (771 km)

Compare bus with

Bus
Most popular
Flight
Train
Driving

$94

Average price

Cheapest

$213

Average price

$258

Average price

$284

Average price

(fuel + tolls)

17h 16m

Average total duration

16h 46m

Onboard

+

30m

Additional time*

4h 52m

Average total duration

Fastest

1h 52m

Onboard

+

3h 0m

Additional time*

20h 33m

Average total duration

20h 3m

Onboard

+

30m

Additional time*

11h 54m

Average total duration

(door-to-door)

0.8 - 1.9kg

CO2 emissions

Lowest

2.3 - 4.6kg

CO2 emissions

-

CO2 emissions

-

CO2 emissions

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Pisa to Prague is a bus with an average price of $94 (€77).

This is compared to other travel options from Pisa to Prague:

A bus is $119 (€97) less than a flight for this route with tickets for a flight from Pisa to Prague costing on average $213 (€175).

A bus is $165 (€135) less than a train for this route with tickets for a train from Pisa to Prague costing on average $258 (€212).

The fastest way to travel from Pisa to Prague is by flight with an average journey time of 1h 52m.

Other travel options to Prague take longer:

Bus takes on average 16h 46m.

Train takes on average 20h 3m.

It's helpful to compare your options as there are 3 ways to travel between Pisa and Prague including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Pisa to Prague among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $94 (€77) compared to roughly $284 (€234) in fuel and tolls — a saving of about $191 (€156). The journey takes 16h 46m versus 11h 54m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Direct services are operated by FlixBus.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Pisa to Prague Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
06:25AM
Arrival Time
03:15AM
Duration
20h50
Departure days
Mon, Sun
Cheapest price
$209
Operator
FlixBus
Departure Time
07:15AM
Arrival Time
03:15AM
Duration
20h00
Departure days
Tue, Thu, Fri, Sat
Cheapest price
$166
Operator
FlixBus
Departure Time
09:40AM
Arrival Time
07:00AM
Duration
21h20
Departure days
Everyday
Cheapest price
$102
Operator
FlixBus
Departure Time
05:10PM
Arrival Time
11:30AM
Duration
18h20
Departure days
Everyday
Cheapest price
$95
Operator
FlixBus
Departure Time
06:10PM
Arrival Time
02:35PM
Duration
20h25
Departure days
Wed, Thu, Fri, Sat, Sun
Cheapest price
$117
Operator
FlixBus
Departure Time
10:00PM
Arrival Time
08:20PM
Duration
22h20
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$122

Live departures

Pisa to Prague bus times

The table below shows live departures for Pisa to Prague buses for today, Sunday, July 19. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus · FlixBus · FlixBus5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
18h35
11:45 AM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus · FlixBus5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
18h20
11:30 AM Praha, Zličín2 transfers
FlixBusFlixBus · FlixBus5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
17h25
10:35 AM Prague, Central Train Station1 transfer
FlixBusFlixBus5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
16h15
9:25 AM Praha, ÚAN Florenc0 transfersDirect
FlixBusFlixBus · FlixBus · FlixBus5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
23h00
4:10 PM Praha, Černý Most2 transfers
FlixBusFlixBus · FlixBus · FlixBus6:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
20h25
2:35 PM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus · FlixBus10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
19h30
5:30 PM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus · FlixBus10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
19h45
5:45 PM Praha, ÚAN Florenc2 transfers
FlixBusFlixBus · FlixBus · FlixBus10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
22h20
8:20 PM Praha, Na Knížecí2 transfers
Monday, July 20
FlixBusFlixBus · FlixBus · FlixBus6:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
20h50
3:15 AM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus · FlixBus9:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
20h05
5:45 AM Praha, ÚAN Florenc2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Pisa to Prague by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Pisa to Prague buses with Omio?

FlixBus operates all buses services from Pisa to Prague.
Omio is an official ticket reseller for all your travel options from Pisa to Prague.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Prague.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Prague.

Journey information

Overview: Bus from Pisa to Prague

ItalyItaly
CzechiaCzechia
Icon of bus

Buses from Pisa to Prague run on average 12 times per day, taking around 16h 46m. Cheap bus tickets for this journey start at $62 (€51) but you can travel from only $28 (€23) by flight.

There are 1 buses per day. The earliest bus runs at 01:00, the last at 23:50. The fastest bus covers the 479 miles (771 km) distance in 16h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $28 (€23)
Distance
479 miles (771 km)
Average bus duration
16h 46m
Cheapest ticket price
$62 (€51)
Buses per day
12
Direct buses
1
Fastest bus
16h 5m
First bus
1:00 AM
Last bus
11:50 PM
Cheapest Month
Jul
Cheapest Day
Mon
High Season
Oct - Dec
Low Season
Apr - Jun
Busiest Day
Wed
Least Busy Day
Sat
Best time to book
42 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $28 (€23)

Bus providers: FlixBus from Pisa to PragueYou can travel by bus between Pisa to Prague with FlixBus for as low as $28 (€23). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
16h 5m
Cheapest Price
$62 (€51)
FlixBus frequency
12 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Complete guide to Prague

Things to do in Prague

Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.

  • Must visit

National Museum

Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.

  • Must visit

Jewish Museum in Prague

Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.

  • Recommended

National Gallery Prague – Schwarzenberg Palace

Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.

Czech koruna (Kč)

Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.

Average meal costs

Budget
Kč150-Kč250 for fast food or street food.
Mid-range
Kč300-Kč600 per person for a meal.
Fine dining
Kč1,200+ per person for upscale restaurants.
Coffee
Kč55-Kč85 for cappuccino.

Tipping culture

Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.

FAQs: Bus from Pisa to Prague

Find answers to the most common questions about traveling from Pisa to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Pisa to Prague can start from as little as $62 (€51) when you book in advance. The average bus ticket price for Pisa to Prague is $94 (€77) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Pisa to Prague is 16h 5m to travel the 479 miles (771 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Pisa to Prague leaves at 1:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Pisa to Prague leaves at 11:50 PM.
Yes, there are 1 direct buses a day from Pisa to Prague with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Pisa to Prague, you can count on FlixBus for the best way to get you to Prague. You can also check all possible bus companies who offer a service between Pisa and Prague and compare the amenities they offer before buying a bus ticket.
When departing from Pisa , you have various bus station options to start your journey from including Pisa, Via delle Fiamme Gialle (Park Pietrasantina), Pisa (Pisamover via San Giusto/Aurelia) . When arriving in Prague , you can end your journey in bus stations like Prague, Central Train Station, Praha, ÚAN Florenc, Praha, Na Knížecí, Praha, Černý Most, Praha, Zličín, Praha, Roztyly, Praha, M. Horákové (Hradčanská), Praha, Letiště Václava Havla .Passengers board the bus most frequently from Pisa, Via delle Fiamme Gialle (Park Pietrasantina), which is located around away from the city centre, and they get off the bus at Prague, Central Train Station, located 1 away from the city centre.
A trip to Prague from Pisa is worth doing but not as a day trip with a journey time of 16h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Pisa to Prague is July.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Prague including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Pisa to Prague:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Pisa to Prague for bus company FlixBus.
Some of the most interesting sights to explore in Prague are:
  • Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
  • Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
  • Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
  • St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
  • The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
The best things to do in Prague include:
  • Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
  • Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
  • Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
  • Visit the National Museum to delve into Czech history and culture
  • Enjoy a classical music concert in one of Prague's historic churches or concert halls.
Whether you can cancel your bus ticket from Pisa to Prague depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Pisa to Prague.
Yes, the following luggage options are included when booking a bus ticket from Pisa to Prague:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Prague:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Pisa to Prague. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Pisa to Prague with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Pisa to Prague with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Pisa to Prague with the following bus company: FlixBus.
Since both Pisa and Prague are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Pisa to Prague among Omio's users.
The currency used in Czechia is the Czech koruna (CZK). While many places accept card payments, cash is still widely used, especially in smaller shops and markets, so travelers should carry some cash but can also use cards conveniently in most urban areas.
In Prague, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, Old Town Square, and major tourist sites. Common scams include overpriced taxi rides without meters, street vendors selling fake tickets or souvenirs, and distraction techniques used by thieves. It's advisable to use official taxis or ride-hailing apps, keep valuables secure, and be wary of strangers offering unsolicited help.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Pisa to Prague

Most Pisa to Prague buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Pisa and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Pisa
Arrival bus stations in Prague
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)Pisa Pietrasantina Parking, Via delle Fiamme Gialle 390, 56123
City-centre transport

Getting to Pisa, Via delle Fiamme Gialle (Park Pietrasantina) from Pisa city centre

Bus21, E24, 1+ · 12m · $1 · every ~10 min
1+, 21 · 14m · $1 · every ~9 min
1+ · 24m · $2 · every ~9 min
21 · 30m · $2
Pisa, Aeroporto Parcheggio Aurelia
City-centre transport

Getting to Pisa, Aeroporto Parcheggio Aurelia from Pisa city centre

Bus15 · 5m · $1 · every ~3 min
15 · 7m · $1 · every ~3 min
15 · 9m · $1 · every ~3 min

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