The cheapest and fastest buses from Pisa to Prague
Cheapest price
$62
Average price
$107
Fastest journey
16 h 5 m
Average duration
19 h 5 m
Buses per day
5
Distance
771 km
The best way to find a cheap bus ticket from Pisa to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Prague will cost around $107 if you buy it on the day, but the cheapest tickets can be found for only $62.
Of the 5 buses that leave Pisa for Prague on Thu, Mar 05, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Mar 05 the direct buses cover the 771 km distance in an average of 19 h 5 m but if you time it right, some buses will get you there in just 16 h 5 m .
On Thu, Mar 05 the slowest buses will take 21 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare train, bus, and flight for Pisa to Prague
Omio recommends booking the flight as it is the most popular option from Pisa to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $61. For those with little time consider booking a flight which can get you there in 2h 26m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.8 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of $61, and a train costs an average of $227.
Distance: 479 miles (771 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$100 Average price Cheapest | $126 Average price | $260 Average price |
17h 16m Average total duration 16h 46m Onboard + 30m Additional time* | 5h 26m Average total duration Fastest 2h 26m Onboard + 3h 0m Additional time* | 20h 44m Average total duration 20h 14m Onboard + 30m Additional time* |
0.8 - 1.9kg CO2 emissions Lowest | 2.3 - 4.6kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Pisa to Prague Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:45AM | Arrival Time 03:15AM | Duration 22h30 | Departure days Fri | Cheapest price $98 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 03:15AM | Duration 20h50 | Departure days Mon, Sat | Cheapest price $74 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 05:45AM | Duration 22h30 | Departure days Mon, Fri, Sat | Cheapest price $77 |
Operator FlixBus | Departure Time 01:50PM | Arrival Time 10:35AM | Duration 20h45 | Departure days Mon | Cheapest price $74 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 08:00PM | Duration 26h40 | Departure days Mon, Wed, Fri, Sat | Cheapest price $78 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 05:45PM | Duration 23h35 | Departure days Wed, Fri, Sat | Cheapest price $96 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 05:45PM | Duration 19h45 | Departure days Mon, Fri, Sat | Cheapest price $74 |
Live departures
Pisa to Prague bus times
The table below shows live departures for Pisa to Prague buses for tomorrow, Thursday, March 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:45 AM Pisa | 21h30 | 2:15 AM Prague | 0 transfersDirect | |
![]() | 5:25 AM Pisa | 20h50 | 2:15 AM Prague | 0 transfersDirect | |
![]() | 8:40 AM Pisa | 20h20 | 5:00 AM Prague | 0 transfersDirect | |
![]() | 3:45 PM Pisa | 16h40 | 8:25 AM Prague | 0 transfersDirect | |
![]() | 4:20 PM Pisa | 16h05 | 8:25 AM Prague | 0 transfersDirect |
Find all the dates and times for this journey
Compare prices and tickets Pisa to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 05
Mar 06
Mar 07
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Mar 13
Mar 14
Mar 15
Mar 16
Mar 17
Mar 18
Mar 19
Mar 20
Mar 21
Mar 22
Mar 23
Mar 24
Mar 25
Why should you book Pisa to Prague buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Prague.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Prague.
Journey information
Overview: Bus from Pisa to Prague
Buses from Pisa to Prague run on average 12 times per day, taking around 16h 46m. Cheap bus tickets for this journey start at $61 (€49) but you can travel from only $25 (€20) by flight.
There are 1 buses per day. The earliest bus runs at 01:00, the last at 23:50. The fastest bus covers the 479 miles (771 km) distance in 16h 5m.
Distance 479 miles (771 km) |
Average bus duration 16h 46m |
Cheapest ticket price $61 (€49) |
Buses per day 12 |
Direct buses 1 |
Fastest bus 16h 5m |
First bus 01:00 |
Last bus 23:50 |
Bus providers: FlixBus from Pisa to PragueYou can travel by bus between Pisa to Prague with FlixBus for as low as $25 (€20). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Pisa to Prague
Find answers to the most common questions about traveling from Pisa to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Pisa to Prague
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
Most popular bus connections from Pisa
More options for your journey from Pisa to Prague
Here are some other resources that might have the information you need
