- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price on Oct 19
$76
Average ticket price on Oct 19
$86
Fastest journey on Oct 19
16 h 15 m
Average journey duration on Oct 19
17 h 8 m
Buses on Oct 19
22
Distance
771 km
The best way to find a cheap bus ticket from Pisa to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Prague will cost around $86 if you buy it on the day, but the cheapest tickets can be found for only $76.
On Mon, Oct 19, we found 22 buses from Pisa to Prague, including 2 direct services.
On Mon, Oct 19 the direct buses cover the 771 km distance in an average of 17 h 8 m but if you time it right, some buses will get you there in just 16 h 15 m .
On Mon, Oct 19 the slowest buses will take 18 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
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FlixBus · FlixBus · FlixBusBuses from Pisa to Prague run on average 10 times per day, taking around 16h 59m. Cheap bus tickets for this journey start at $58 (€48) but you can travel from only $12 (€10) by train.
There are 1 buses per day. The earliest bus runs at 01:00, the last at 23:50. The fastest bus covers the 479 miles (771 km) distance in 14h 40m.
Distance 479 miles (771 km) |
Average bus duration 16h 59m |
Cheapest ticket price $58 (€48) |
Buses per day 10 |
Direct buses 1 |
Fastest bus 14h 40m |
First bus 1:00 AM |
Last bus 11:50 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 28 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:45AM | Arrival Time 03:15AM | Duration 22h30 | Departure days Tue | Cheapest price $79 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 03:15AM | Duration 20h50 | Departure days Mon | Cheapest price $106 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 03:15AM | Duration 20h00 | Departure days Everyday | Cheapest price $81 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 05:45AM | Duration 20h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $80 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 11:30AM | Duration 18h20 | Departure days Everyday | Cheapest price $76 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 02:35PM | Duration 20h25 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $115 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 05:45PM | Duration 19h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $82 |
The table below shows live departures for Pisa to Prague buses for today, Sunday, October 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 23h00 | 4:10 PM Praha, Černý Most | 2 transfers | |
FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h15 | 9:25 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 17h25 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h35 | 12:45 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 18h20 | 11:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h25 | 2:35 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 22h20 | 8:20 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h30 | 5:30 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h45 | 5:45 PM Praha, ÚAN Florenc | 2 transfers | |
| Monday, October 19 | |||||
FlixBus · FlixBus · FlixBus | 6:25 AM Pisa (Pisamover via San Giusto/Aurelia) | 20h50 | 3:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h50 | 3:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 7:15 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 22h30 | 5:45 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:40 AM Pisa (Pisamover via San Giusto/Aurelia) | 20h05 | 5:45 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 21h20 | 7:00 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h05 | 5:45 AM Praha, ÚAN Florenc | 2 transfers | |
Find all the dates and times for this journey
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Pisa to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Pisa to Prague buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Pisa and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) is 1 km from Pisa city centre. Public transport options include:
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, Ticket Office, Bike Parking, and Bike Rental.
Wi-Fi is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina). ATMs are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Ticket office support is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Parking, Taxis, WC.
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): The station is accessible for people with reduced mobility.
Pisa (Pisamover via San Giusto/Aurelia) is 1 km from Pisa city centre. Public transport options include:
Pisa (Pisamover via San Giusto/Aurelia) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Pisa (Pisamover via San Giusto/Aurelia). ATMs are available at Pisa (Pisamover via San Giusto/Aurelia).
Ticket office support is available at Pisa (Pisamover via San Giusto/Aurelia).
Available at Pisa (Pisamover via San Giusto/Aurelia): Parking, Taxis, WC.
Accessibility facilities are available at Pisa (Pisamover via San Giusto/Aurelia): Wheelchair accessible with assistance.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
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