The cheapest and fastest trains from Lyon to Prague
Cheapest price
$325
Average price
$345
Fastest journey
21 h 20 m
Average duration
21 h 45 m
Trains per day
2
Distance
860 km
The best way to find a cheap train ticket from Lyon to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Prague will cost around $345 if you buy it on the day, but the cheapest tickets can be found for only $325.
It's difficult to get from Lyon to Prague without transferring at least 4 times.
TGV 9583+
ICE 1229 · Bus EV · 383510:01 AM21h20Lyon Part Dieu7:21 AMPrague hlavní nádraží$3251One-way5 transfers
TGV 9583+
ICE 2517 · S1 · 2801810:01 AM22h09Lyon Part Dieu8:10 AMPrague hlavní nádraží$3641One-way4 transfers
TGV 9583+
ICE 1229 · Bus EV · 383510:01 AM21h20Lyon Part Dieu7:21 AMPrague hlavní nádraží$3251One-way5 transfers
TGV 9583+
ICE 2517 · S1 · 2801810:01 AM22h09Lyon Part Dieu8:10 AMPrague hlavní nádraží$3641One-way4 transfers
Travel Information
Compare bus, train, and flight for Lyon to Prague
Omio recommends booking the flight as it is the most popular option from Lyon to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $60. For those with little time consider booking a flight which can get you there in 2h 38m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $60, and a train costs an average of $284.
Distance: 534 miles (860 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
$319 Average price | $195 Average price | $88 Average price Cheapest |
12h 54m Average total duration 12h 24m Onboard + 30m Additional time* | 5h 38m Average total duration Fastest 2h 38m Onboard + 3h 0m Additional time* | 16h 49m Average total duration 16h 19m Onboard + 30m Additional time* |
- CO2 emissions | 2.6 - 5.2kg CO2 emissions | 0.9 - 2.1kg CO2 emissions Lowest |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Lyon to Prague train times
The table below shows live departures for Lyon to Prague trains for tomorrow, Wednesday, April 15. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
TGV 9583+ ICE 2517 · S1 · 28018 | On time 8:01 AM Lyon Part Dieu | 22h09 | 6:10 AM Prague hlavní nádraží | 4 transfers | |
TGV 9583+ ICE 1229 · Bus EV · 3835 | On time 8:01 AM Lyon Part Dieu | 21h20 | 5:21 AM Prague hlavní nádraží | 5 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Prague by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Lyon to Prague
Trains from Lyon to Prague run on average 1 times per day, taking around 12h 24m. Cheap train tickets for this journey start at $284 (€226) but you can travel from only $55 (€44) by flight.
The earliest train runs at 05:05, the last at 17:00. The fastest train covers the 534 miles (860 km) distance in 13h 18m.
Distance 534 miles (860 km) |
Average train duration 12h 24m |
Cheapest ticket price $284 (€226) |
Trains per day 1 |
Fastest train 13h 18m |
First train 5:05 AM |
Last train 5:00 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Sat |
Least Busy Day Tue |
Best time to book 49 days |
Train companies: TGV from Lyon to Prague trainsTGV trains will get you between Lyon and Prague from $55 (€44). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
TGV
FAQs: Trains from Lyon to Prague
Find answers to the most common questions about traveling from Lyon to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Lyon to Prague
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Free unlimited WiFi.
- Luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk.
- Alto Café
- Paul
- Paul The Café
- Starbucks
- Exki
- Sushi Shop
- Carrefour
- Complimentary personalized care is available.
- Radisson Blu Hotel Lyon
- Mercure Lyon Center
- ibis Styles Lyon Center
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Located in the station's main hall.
- Metro lines: A, B, C, D
- Tram lines: T4, K240, T3, K100
- Bus lines: 2960, C2, C3, C6, C9
- Train lines: TGV, TGV Lyria, TGV INOUI, OUIGO, TER, Intercités, Eurostar, AVE
- Mon - Fri: 10:00 - 18:00
- Free, unlimited Wi-Fi is available after creating an account and connecting to "CONNECTION."
- PAUL
- Hearing, mobility, and visual disability assistance. Accessibility available with elevator, ramp or step-free access, barrier-free toilets.
- Mercure Lyon Centre Chateau Perrache
- Hotel De Normandie
- InterContinental Lyon-Hotel Dieu
- Mon - Fri: 10:00 - 18:00
- Information services are available at the ticket office, located in Hall Level 2.
- Metro lines: A, B, C, D
- Bus lines: 8, 31, 46, 49, 55, 60, 63, S1, C19, C21, C22
- Tram lines: 1, 2
- Train lines: TGV, TGV INOUI, OUIGO, TER Auvergne-Rhône-Alpes, Intercités
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
More options for your journey from Lyon to Prague
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