- Must visit
Uffizi Gallery
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
Flights from Washington, DC to Florence, SC depart on average 24 times per day, taking around 3h 14m. Cheap flight tickets for this journey start at $484 but you can travel from only $61 by bus.
The earliest flight runs at 14:06, the last at 23:24. The fastest flight covers the 357 miles (576 km) distance in 2h 24m. June is the cheapest month to fly.
Distance 357 miles (576 km) |
Average flight duration 3h 14m |
Cheapest ticket price $484 |
Flights per day 24 |
Fastest flight 2h 24m |
First flight 2:06 PM |
Last flight 11:24 PM |
Cheapest Month Jun |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Sun |
Least Busy Day Sun |
Omio recommends booking the train as it is the most popular option from Washington, DC to Florence, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $106 For those with little time, consider booking a flight, which has an average total journey time of 5h 14m. Average ticket prices depend on the travel mode: a bus costs an average of $106, while a flight costs an average of $745.
Distance: 357 miles (576 km)
| Flight | Most popular Train | Bus |
|---|---|---|
$745 Average price | $222 Average price | $106 Average price Cheapest |
5h 14m Average total duration Fastest 3h 14m Onboard + 2h 0m Additional time* | 8h 18m Average total duration 7h 48m Onboard + 30m Additional time* | 8h 25m Average total duration 7h 55m Onboard + 30m Additional time* |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Washington, DC to Florence, SC:
A bus is $116 less than a train for this route with tickets for a train from Washington, DC to Florence, SC costing on average $222.
A bus is $639 less than a flight for this route with tickets for a flight from Washington, DC to Florence, SC costing on average $745.
Other travel options to Florence, SC take longer:
Train takes on average 7h 48m.
Bus takes on average 7h 55m.
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Florence, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence, SC trip today.
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
Museum centered on Michelangelo’s David, plus sculptures and paintings. Essential for seeing one of Florence’s most famous masterpieces up close.
Interactive museum inside the cathedral complex exploring Brunelleschi’s dome, tools, and original artworks. Ideal for understanding Florence’s cathedral story.
Grand civic square framed by Palazzo Vecchio and open-air sculptures. It is one of Florence’s key meeting points and a natural starting place for exploration.
Hilltop terrace with sweeping city views, especially at sunset. A classic Florence panorama and a rewarding walk or short bus ride from the center.
Large formal garden behind Pitti Palace with paths, fountains, and viewpoints. Excellent for a slower visit combining greenery, sculpture, and city vistas.
Find answers to the most common questions about traveling from Washington, DC to Florence, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

Most Washington, DC to Florence, SC flights use the Ronald Reagan National Airport to Florence Regional Airport airport pair. Use this guide to compare Washington, DC and Florence, SC airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Ronald Reagan National Airport is 4 km from Washington city centre. Public transport options include:
Ronald Reagan National Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants are located in all terminals, offering American, Italian, and fast food options; top choices include Legal Sea Foods and Five Guys.
Free Wi-Fi available throughout the airport. ATMs are located throughout the airport, near ticketingas and baggage claim.
Lost and found is available at the station.
Available at Ronald Reagan National Airport: Parking, Taxis, WC.
Available at Ronald Reagan National Airport: Car Rental.
Accessibility facilities are available at Ronald Reagan National Airport: Elevators, ramps, assistance.
Nearby hotels include Hotels within walking distance, including the Crystal Gateway Marriott..
Dulles International Airport is 3 km from Washington city centre. Public transport options include:
Dulles International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants located in all concourses; options include fast food, cafes, and sit-down dining like Five Guys and Chipotle.
Free Wi-Fi available throughout the airport. ATMs are located throughout the airport in all terminals.
Lost and found is available at the station.
Available at Dulles International Airport: Parking, Taxis, WC.
Available at Dulles International Airport: Car Rental.
Accessibility facilities are available at Dulles International Airport: Elevators, ramps, assistance.
Nearby hotels include Hotels nearby include Washington Dulles Airport Marriott within walking distance..
Florence Regional Airport is 3 km from Florence city centre. Public transport options include:
Florence Regional Airport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi is available throughout the terminal. ATMs are aTM available inside the terminal.
Ticket office support is available at Florence Regional Airport.
Available at Florence Regional Airport: Parking, Taxis, WC.
Accessibility facilities are available at Florence Regional Airport: Facilities are accessible to passengers with reduced mobility.
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