- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Cheapest price on Sep 19
$439
Average ticket price on Sep 19
$522
Fastest journey on Sep 19
3 d 6 h
Average journey duration on Sep 19
3 d 6 h
Buses on Sep 19
2
Distance
3911 km
The best way to find a cheap bus ticket from Syracuse, NY to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse, NY to San Francisco, CA will cost around $522 if you buy it on the day, but the cheapest tickets can be found for only $439.
On Sat, Sep 19, we found 2 buses from Syracuse, NY to San Francisco, CA, including 2 direct services.
On Sat, Sep 19 the direct buses cover the 3911 km distance in an average of 3 d 6 h but if you time it right, some buses will get you there in just 3 d 6 h .
On Sat, Sep 19 the slowest buses will take 3 d 6 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the flight as it is the most popular option from Syracuse, NY to San Francisco, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $547 For those with little time, consider booking a flight, which has an average total journey time of 9h 54m. Average ticket prices depend on the travel mode: a bus costs an average of $547, while a flight costs an average of $734.
Distance: 2430 miles (3911 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$547 Average price Cheapest | $734 Average price | $628 Average price | $632 Average price (fuel + tolls) |
65h 15m Average total duration 64h 45m Onboard + 30m Additional time* | 9h 54m Average total duration Fastest 7h 54m Onboard + 2h 0m Additional time* | 67h 29m Average total duration 66h 59m Onboard + 30m Additional time* | 40h 57m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Syracuse, NY to San Francisco, CA:
A bus is $82 (€67) less than a train for this route with tickets for a train from Syracuse, NY to San Francisco, CA costing on average $628 (€514).
A bus is $187 (€153) less than a flight for this route with tickets for a flight from Syracuse, NY to San Francisco, CA costing on average $734 (€600).
Other travel options to San Francisco, CA take longer:
Bus takes on average 64h 45m.
Train takes on average 66h 59m.
Tickets start at around $547 (€447) compared to roughly $632 (€517) in fuel and tolls — a saving of about $86 (€70). The journey takes 64h 45m versus 40h 57m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:20AM | Arrival Time 03:15PM | Duration 86h55 | Departure days Sat | Cheapest price $460 |
Operator Greyhound | Departure Time 01:00AM | Arrival Time 06:05PM | Duration 89h05 | Departure days Fri | Cheapest price $373 |
Operator Greyhound | Departure Time 03:55AM | Arrival Time 08:45AM | Duration 79h50 | Departure days Sun | Cheapest price $285 |
Operator Greyhound | Departure Time 01:25PM | Arrival Time 07:25PM | Duration 78h00 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $197 |
Operator Greyhound | Departure Time 02:25PM | Arrival Time 07:25PM | Duration 77h00 | Departure days Mon, Tue, Wed, Fri, Sat | Cheapest price $394 |
Operator Greyhound | Departure Time 07:35PM | Arrival Time 05:55PM | Duration 73h20 | Departure days Sun | Cheapest price $254 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 08:45AM | Duration 86h45 | Departure days Sun | Cheapest price $248 |
Operator Greyhound | Departure Time 11:35PM | Arrival Time 07:25PM | Duration 67h50 | Departure days Tue, Fri | Cheapest price $223 |
The table below shows live departures for Syracuse, NY to San Francisco, CA buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:25 PM Syracuse, NY | 78h00 | 7:25 PM San Francisco, CA | 0 transfersDirect | |
![]() | 2:25 PM Syracuse, NY | 77h00 | 7:25 PM San Francisco, CA | 0 transfersDirect | |
![]() | 11:35 PM Syracuse, NY | 67h50 | 7:25 PM San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Syracuse, NY to San Francisco, CA run on average 2 times per day, taking around 64h 45m. Cheap bus tickets for this journey start at $412 (€336) but you can travel from only $402 (€328) by flight.
The earliest bus runs at 06:30, the last at 23:25. The fastest bus covers the 2430 miles (3911 km) distance in 62h 40m.
Distance 2430 miles (3911 km) |
Average bus duration 64h 45m |
Cheapest ticket price $412 (€336) |
Buses per day 2 |
Fastest bus 62h 40m |
First bus 6:30 AM |
Last bus 11:25 PM |
Cheapest Month Jan |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Oct - Dec |
Discover the best of San Francisco, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco, CA trip today.
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
Find answers to the most common questions about traveling from Syracuse, NY to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

Most Syracuse, NY to San Francisco, CA buses use the Syracuse, Walsh Cir (Syracuse Bus Station) to San Francisco, Transit Center Bay 29 station pair, with some services arriving at San Francisco, Townsend Street / 5th Street. Use this guide to compare Syracuse, NY and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Syracuse, Walsh Cir (Syracuse Bus Station) is 3 km from Syracuse city centre. Public transport options include:
Syracuse, Walsh Cir (Syracuse Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available throughout the station. ATMs are aTMs are located near the entrance.
Ticket office support is available at Syracuse, Walsh Cir (Syracuse Bus Station).
Available at Syracuse, Walsh Cir (Syracuse Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Syracuse, Walsh Cir (Syracuse Bus Station): The station is wheelchair accessible.
San Francisco, Transit Center Bay 29 is 2 km from San Francisco city centre. Public transport options include:
San Francisco, Transit Center Bay 29 has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Francisco, Transit Center Bay 29. ATMs are available at San Francisco, Transit Center Bay 29.
Ticket office support is available at San Francisco, Transit Center Bay 29.
Available at San Francisco, Transit Center Bay 29: Parking, Taxis, WC.
Accessibility facilities are available at San Francisco, Transit Center Bay 29: Wheelchair accessible areas present.
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