- Must visit
San Antonio Museum of Art
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
The best way to find a cheap bus ticket from Rochester, NY to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rochester, NY to San Antonio, TX will cost around €314 if you buy it on the day, but the cheapest tickets can be found for only €279.
On Thu, Nov 05, we found 2 buses from Rochester, NY to San Antonio, TX, including 2 direct services.
On Thu, Nov 05 the direct buses cover the 2403 km distance in an average of 2 d 12 h 50 m but if you time it right, some buses will get you there in just 2 d 3 h 5 m .
On Thu, Nov 05 the slowest buses will take 2 d 22 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Rochester, NY to San Antonio, TX run on average 5 times per day, taking around 46h 25m. Cheap bus tickets for this journey start at €130 if you book in advance.
The earliest bus runs at 01:20, the last at 23:35. The fastest bus covers the 1493 miles (2403 km) distance in 37h 20m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Rochester, NY to San Antonio, TX.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:35AM | Arrival Time 02:10AM | Duration 70h35 | Departure days Thu | Cheapest price €279 |
Operator Greyhound USA | Departure Time 06:10AM | Arrival Time 01:18PM | Duration 55h08 | Departure days Fri, Sat | Cheapest price €412 |
Operator Greyhound | Departure Time 10:10AM | Arrival Time 04:55AM | Duration 42h45 | Departure days Thu | Cheapest price €225 |
Operator Greyhound | Departure Time 07:30PM | Arrival Time 10:35PM | Duration 51h05 | Departure days Wed | Cheapest price €349 |
Buses from Rochester, NY to San Antonio, TX with Greyhound and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of San Antonio, TX — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio, TX trip today.
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
This leading Latinx art museum showcases contemporary and historic works, making it one of the city’s most distinctive cultural stops.
Housed in a former brewery, this contemporary art museum presents rotating exhibitions in one of San Antonio’s most atmospheric spaces.
The city’s signature pedestrian corridor links shops, boats, bridges, and historic architecture, making it San Antonio’s essential walking experience.
This artsy, fast-evolving district mixes galleries, murals, boutiques, and nightlife with a strong local identity near the river.
A lively downtown plaza framed by major civic buildings, it is best known for events, fountains, and the nightly cathedral light show nearby.
Puffy tacos are San Antonio’s signature dish: crisp, airy fried corn tortillas filled with picadillo, chicken, or beans, rooted in local Tex-Mex history.
Barbacoa is slow-cooked beef, often served on weekends in breakfast tacos. It is a beloved South Texas tradition with deep Mexican roots.
Breakfast tacos are a daily staple in San Antonio, usually filled with egg, potato, bean, bacon, or chorizo in flour or corn tortillas.
Refined River Walk restaurant serving upscale South Texas and Mexican cuisine. Elegant atmosphere with a long-standing fine dining reputation.
Popular breakfast and lunch spot known for house-made tortillas, tacos, and classic San Antonio Tex-Mex in a relaxed setting.
Beloved market restaurant for authentic Mexican dishes, fresh tortillas, and bakery items. Bustling, traditional atmosphere.
Moderate for a major U.S. city. Hotels and dining are usually cheaper than New York or San Francisco, while car use can add costs because transit is limited.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-$2 per drink or coffee if there is table or bar service.
Official public transport app
UTSA East Campus Lot 1 -> Downtown San Antonio
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in San Antonio, TX.
Find answers to the most common questions about traveling from Rochester, NY to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

Most Rochester, NY to San Antonio, TX buses use the Rochester, Pleasant St (Greyhound Stop) to San Antonio, N St Mary's St (Greyhound) station pair, with some services arriving at San Antonio, Avenue A / Pearl Pkwy. Use this guide to compare Rochester, NY and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Rochester, Pleasant St (Greyhound Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Rochester, Pleasant St (Greyhound Stop). ATMs are available at Rochester, Pleasant St (Greyhound Stop).
Ticket office support is available at Rochester, Pleasant St (Greyhound Stop).
Available at Rochester, Pleasant St (Greyhound Stop): Parking, Taxis, WC.
Accessibility facilities are available at Rochester, Pleasant St (Greyhound Stop): Accessible for disabled passengers.
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
Check bus stations information for Rochester, NY and San Antonio, TX, including where buses depart and arrive on this route.