- Must visit
Uffizi Gallery
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
The best way to find a cheap train ticket from Orlando, FL to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Florence, SC will cost around $216 if you buy it on the day, but the cheapest tickets can be found for only $216.
On Tue, Nov 03, we found 1 trains from Orlando, FL to Florence, SC, including 1 direct services.
On Tue, Nov 03 the direct trains cover the 647 km distance in an average of 9 h 46 m but if you time it right, some trains will get you there in just 9 h 46 m .
On Tue, Nov 03 the slowest trains will take 9 h 46 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Trains from Orlando, FL to Florence, SC run on average 2 times per day, taking around 9h 32m. Cheap train tickets for this journey start at $81 but you can travel from only $66 by bus.
There are 1 trains per day. The earliest train runs at 03:18, the last at 20:48. The fastest train covers the 402 miles (647 km) distance in 9h 17m.
Distance 402 miles (647 km) |
Average train duration 9h 32m |
Cheapest ticket price $81 |
Trains per day 2 |
Direct trains 1 |
Fastest train 9h 17m |
First train 3:18 AM |
Last train 8:48 PM |
Cheapest Month Nov |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 63 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Orlando, FL to Florence, SC.
The table below shows live departures for Orlando, FL to Florence, SC trains for today, Monday, November 2. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:50 PM Orlando, FL | 15h59 | 2:49 PM Florence, SC | 0 transfersDirect | |
| Tuesday, November 3 | |||||
![]() | 1:36 PM Orlando, FL | 9h46 | 11:22 PM Florence, SC | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Florence, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence, SC trip today.
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
Museum centered on Michelangelo’s David, plus sculptures and paintings. Essential for seeing one of Florence’s most famous masterpieces up close.
Interactive museum inside the cathedral complex exploring Brunelleschi’s dome, tools, and original artworks. Ideal for understanding Florence’s cathedral story.
Grand civic square framed by Palazzo Vecchio and open-air sculptures. It is one of Florence’s key meeting points and a natural starting place for exploration.
Hilltop terrace with sweeping city views, especially at sunset. A classic Florence panorama and a rewarding walk or short bus ride from the center.
Large formal garden behind Pitti Palace with paths, fountains, and viewpoints. Excellent for a slower visit combining greenery, sculpture, and city vistas.
Pulled pork barbecue is a Pee Dee staple, slow-smoked until tender and served with the region's tangy vinegar-pepper sauce.
Smoked pork ribs are common at local barbecue joints, seasoned simply and cooked low and slow for deep smoke flavor.
Shrimp and grits is a South Carolina classic: local shrimp over creamy grits, often enriched with bacon, gravy, or butter.
Upscale downtown restaurant serving refined Southern dishes, steaks, seafood, and cocktails in a polished space.
Casual local favorite for Carolina barbecue, ribs, and classic Southern sides in a relaxed family setting.
Popular casual spot known for barbecue plates, pulled pork, and generous Southern comfort food portions.
Moderate by U.S. small-city standards. Hotels are usually cheaper than major tourist cities, while dining and car-based transport remain fairly typical for the region.
Tip 15-20% at restaurants. Round up or add 10-15% for taxis if service is good. Small change is fine at cafes.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Florence, SC.
Find answers to the most common questions about traveling from Orlando, FL to Florence, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

Most Orlando, FL to Florence, SC trains use the Orlando Station to Florence Station station pair. Use this guide to compare Orlando, FL and Florence, SC train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Orlando Station is 1 km from Orlando city centre. Public transport options include:
Orlando Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Information Desk, and Luggage Carts.
Food options include: Mary Mary Bar, The Boheme
Ticket office support is available at Orlando Station. Information desks are located in the main hall.
Luggage storage is available at Orlando Station. Lost and found is available at the station.
Available at Orlando Station: Parking, Taxis, WC.
Available at Orlando Station: Bike Parking.
Accessibility facilities are available at Orlando Station: Elevators, ramps, restrooms.
Nearby hotels include Orlando World Center Marriott, Grand Bohemian Hotel Orlando, Aloft Orlando Downtown.
Florence Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Information Desk, and Luggage Carts.
Food and drink options are available at Florence Station.
Ticket office support is available at Florence Station. Information desks are located in the main hall.
Luggage storage is available at Florence Station. Lost and found is available at the station.
Available at Florence Station: Parking, Taxis, WC.
Accessibility facilities are available at Florence Station: Elevators, ramps.
Nearby hotels include Aloft Florence, Hyatt Place Florence Downtown, Hotel Florence, Tapestry Collection by Hilton.
Check train stations information for Orlando, FL and Florence, SC, including where trains depart and arrive on this route.
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