- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Cheapest price on Sep 13
€87
Average ticket price on Sep 13
€90
Fastest journey on Sep 13
19 h 35 m
Average journey duration on Sep 13
20 h 54 m
Buses on Sep 13
4
Distance
1386 km
The best way to find a cheap bus ticket from Orlando, FL to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to St. Louis, MO will cost around €90 if you buy it on the day, but the cheapest tickets can be found for only €87.
It's difficult to get from Orlando, FL to St. Louis, MO without transferring at least once.
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Omio recommends booking the flight as it is the most popular option from Orlando, FL to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €117 For those with little time, consider booking a flight, which has an average total journey time of 7h 27m. Average ticket prices depend on the travel mode: a bus costs an average of €117, while a train costs an average of €605.
Distance: 861 miles (1386 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
€117 Average price Cheapest | €512 Average price | €605 Average price | €173 Average price (fuel + tolls) |
20h 43m Average total duration 20h 13m Onboard + 30m Additional time* | 7h 27m Average total duration Fastest 5h 27m Onboard + 2h 0m Additional time* | 44h 31m Average total duration 44h 1m Onboard + 30m Additional time* | 14h 23m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Orlando, FL to St. Louis, MO:
A bus is €395 less than a flight for this route with tickets for a flight from Orlando, FL to St. Louis, MO costing on average €512.
A bus is €488 less than a train for this route with tickets for a train from Orlando, FL to St. Louis, MO costing on average €605.
Other travel options to St. Louis, MO take longer:
Bus takes on average 20h 13m.
Train takes on average 44h 1m.
Tickets start at around €117 compared to roughly €173 in fuel and tolls — a saving of about €56. The journey takes 20h 13m versus 14h 23m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:35AM | Arrival Time 02:15PM | Duration 34h40 | Departure days Thu | Cheapest price €85 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 09:20AM | Duration 21h50 | Departure days Thu | Cheapest price €90 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 03:55PM | Duration 28h10 | Departure days Thu | Cheapest price €83 |
Operator Greyhound | Departure Time 01:05PM | Arrival Time 11:00PM | Duration 34h55 | Departure days Thu | Cheapest price €85 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 02:15PM | Duration 25h15 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price €82 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 02:15PM | Duration 24h30 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price €82 |
Operator FlixBus | Departure Time 08:50PM | Arrival Time 03:55PM | Duration 20h05 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price €86 |
Operator FlixBus | Departure Time 09:05PM | Arrival Time 03:55PM | Duration 19h50 | Departure days Sat | Cheapest price €82 |
Operator Greyhound | Departure Time 10:55PM | Arrival Time 09:30PM | Duration 23h35 | Departure days Everyday | Cheapest price €81 |
The table below shows live departures for Orlando, FL to St. Louis, MO buses for today, Saturday, September 12. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 2:00 PM Orlando, The Florida Mall, FL | 20h20 | 9:20 AM St. Louis, S 15th St (Civic center) | 1 transfer | |
FlixBus · FlixBus | 2:45 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 19h35 | 9:20 AM St. Louis, S 15th St (Civic center) | 1 transfer | |
FlixBus+ · | 9:05 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 19h50 | 3:55 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Orlando, FL to St. Louis, MO run on average 4 times per day, taking around 20h 13m. Cheap bus tickets for this journey start at €69 if you book in advance.
The earliest bus runs at 01:00, the last at 23:45. The fastest bus covers the 861 miles (1386 km) distance in 18h 40m.
Distance 861 miles (1386 km) |
Average bus duration 20h 13m |
Cheapest ticket price €69 |
Buses per day 4 |
Fastest bus 18h 40m |
First bus 1:00 AM |
Last bus 11:45 PM |
Cheapest Month Apr |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 35 days |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Find answers to the most common questions about traveling from Orlando, FL to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Orlando, FL to St. Louis, MO buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis, Lambert International Airport. Use this guide to compare Orlando, FL and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple dining options available in terminals.
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Ticket office support is available at St. Louis, Lambert International Airport.
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
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