Orlando, FL to St. Louis, MO bus with Greyhound

Thu, Nov 06
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Greyhound
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Alsa
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Rede Expressos
1,000+ travel companies
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Travel Information

Compare train, bus, and flight for Orlando, FL to St. Louis, MO

Omio recommends booking the flight as it is the most popular option from Orlando, FL to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from €100. For those with little time consider booking a flight which can get you there in 3h 21m. The ticket price range depends on the travel mode: a bus costs an average of €100, and a train costs an average of €140.

Distance: 861 miles (1386 km)

Compare bus with

Bus
Most popular
Flight
Train

€128

Average price

Cheapest

€128

Average price

€238

Average price

21h 25m

Average total duration

20h 55m

Onboard

+

30m

Additional time*

6h 21m

Average total duration

Fastest

3h 21m

Onboard

+

3h 0m

Additional time*

54h 49m

Average total duration

54h 19m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

Live departures

Orlando, FL to St. Louis, MO bus times

The table below shows live departures for Orlando, FL to St. Louis, MO buses for today, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.

Last updated at 2:57 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus6:00 PM Orlando, FL
26h45
8:45 PM St. Louis, MO0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Orlando, FL to St. Louis, MO by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Nov 07
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Journey information

Overview: Bus from Orlando, FL to St. Louis, MO

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Buses from Orlando, FL to St. Louis, MO run on average 5 times per day, taking around 20h 55m. Cheap bus tickets for this journey start at $122 (€100) but you can travel from only $91 (€74) by flight.

The earliest bus runs at 01:00, the last at 23:30. The fastest bus covers the 861 miles (1386 km) distance in 21h 55m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $91 (€74)
Distance
861 miles (1386 km)
Average bus duration
20h 55m
Cheapest ticket price
$122 (€100)
Buses per day
5
Fastest bus
21h 55m
First bus
01:00
Last bus
23:30
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $91 (€74)

Bus providers: Greyhound, FlixBus from Orlando, FL to St. Louis, MOYou can travel by bus between Orlando, FL to St. Louis, MO with Greyhound, FlixBus for as low as $91 (€74). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Learn more about FlixBus
Luggage & cancellation policy
Average Duration
21h 55m
Cheapest Price
$80 (€65)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Learn more about Greyhound
Luggage & cancellation policy
Average Duration
21h 55m
Cheapest Price
$97 (€80)
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Orlando, FL to St. Louis, MO

Find answers to the most common questions about traveling from Orlando, FL to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Orlando, FL to St. Louis, MO can start from as little as $173 (€141) when you book in advance. The average bus ticket price for Orlando, FL to St. Louis, MO is $220 (€179); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Orlando, FL to St. Louis, MO bus time is 21 h 55 min   covering the 859 mile (1386 km) long journey, but the journey time can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Orlando, FL to St. Louis, MO leaves at 1: 00AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Orlando, FL to St. Louis, MO leaves at 11: 15PM.
There are 5 buses a day from Orlando, FL to St. Louis, MO which require at least one change with Greyhound or FlixBus. Schedules can vary on holidays or weekends with fewer buses.
For the route from Orlando, FL to St. Louis, MO you can take a bus with Greyhound or FlixBus. Be sure to check out all possible bus companies that offer services between Orlando, FL and St. Louis, MO on Omio to compare what amenities they may have.
The cheapest month to travel from Orlando, FL to St. Louis, MO by bus is November.
You have options as you can travel to St. Louis, MO from Orlando, FL 2 different ways: train or bus.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to St. Louis, MO:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to St. Louis, MO for bus companies Greyhound and FlixBus.
Yes, bikes are allowed on board the bus with bus providers Greyhound and FlixBus.
Whether you can cancel your bus ticket from Orlando, FL to St. Louis, MO depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

To find the cheapest bus tickets for your trip from Orlando, FL to St. Louis, MO, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Orlando, FL to St. Louis, MO.
    Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to St. Louis, MO:
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to St. Louis, MO:
    • Greyhound
      • $15 per additional bag.
    • FlixBus
      • Additional luggage can be purchased for a fee.
    Yes, you can bring your pet on the bus from Orlando, FL to St. Louis, MO. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Orlando, FL to St. Louis, MO with the following bus providers: Greyhound and FlixBus
    Yes, there are USB plugs on board the bus from Orlando, FL to St. Louis, MO with the following bus companies: Greyhound and FlixBus.
    Yes, there is Wifi on board the bus from Orlando, FL to St. Louis, MO with the following bus companies: Greyhound and FlixBus.

    popular bus stations

    Popular bus stations from Orlando, FL to St. Louis, MO

    Orlando
    St. Louis
    The major bus station for departures in Orlando is Orlando, The Florida Mall. Find all the information you need to know about services, amenities and connections at Orlando, The Florida Mall for your trip from Orlando to St. Louis.
    Orlando, The Florida Mall
    information
    address
    Address
    Orlando Florida Mall Ave,Florida Mall Ave 1632,32809
    Orlando, N John Young Pkwy (Greyhound Bus Station)
    information

    More options for your journey from Orlando, FL to St. Louis, MO

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