- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
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The cheapest and fastest buses from Chicago, IL to St. Louis, MO
Showing times, prices and bookable tickets for Oct 08
Cheapest price on Oct 08
€47
Average ticket price on Oct 08
€76
Fastest journey on Oct 08
5 h 55 m
Average journey duration on Oct 08
7 h 6 m
Buses on Oct 08
6
Distance
419 km
Cheap tickets
The best way to find a cheap bus ticket from Chicago, IL to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Chicago, IL to St. Louis, MO will cost around €76 if you buy it on the day, but the cheapest tickets can be found for only €47.
Fast buses
On Thu, Oct 08, we found 6 buses from Chicago, IL to St. Louis, MO, including 3 direct services.
On Thu, Oct 08 the direct buses cover the 419 km distance in an average of 7 h 6 m but if you time it right, some buses will get you there in just 5 h 55 m .
On Thu, Oct 08 the slowest buses will take 8 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus5:05 PM6h15Chicago, Greyhound Bus Station11:20 PMSt. Louis, S 15th St (Civic center)€471One-way0 transfers- FlixBus9:45 AM5h55Chicago, Greyhound Bus Station3:40 PMSt. Louis, S 15th St (Civic center)€551One-way0 transfers
- FlixBus12:15 AM6h05Chicago, Greyhound Bus Station6:20 AMSt. Louis, S 15th St (Civic center)€681One-way0 transfers
· 2:45 PM8h30Chicago, Greyhound Bus Station11:15 PMSt. Louis, S 15th St (Civic center)€681One-way1 transfer- · 11:10 PM8h45Chicago, Union Station (Amtrak), IL7:55 AMSt. Louis, S 15th St (Civic center)€1081One-way1 transfer
- FlixBus9:45 AM5h55Chicago, Greyhound Bus Station3:40 PMSt. Louis, S 15th St (Civic center)€551One-way0 transfers
- FlixBus12:15 AM6h05Chicago, Greyhound Bus Station6:20 AMSt. Louis, S 15th St (Civic center)€681One-way0 transfers
- FlixBus5:05 PM6h15Chicago, Greyhound Bus Station11:20 PMSt. Louis, S 15th St (Civic center)€471One-way0 transfers
- · 2:45 PM8h30Chicago, Greyhound Bus Station11:15 PMSt. Louis, S 15th St (Civic center)€681One-way1 transfer
- · 11:10 PM8h45Chicago, Union Station (Amtrak), IL7:55 AMSt. Louis, S 15th St (Civic center)€1081One-way1 transfer
Journey information
Overview: Bus from Chicago, IL to St. Louis, MO
USAUSA
Buses from Chicago, IL to St. Louis, MO run on average 6 times per day, taking around 7h 14m. Cheap bus tickets for this journey start at €23 but you can travel from only €21 by train.
There are 3 buses per day. The earliest bus runs at 00:15, the last at 23:45. The fastest bus covers the 260 miles (419 km) distance in 5h 50m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €21
Distance 260 miles (419 km) |
Average bus duration 7h 14m |
Cheapest ticket price €23 |
Buses per day 6 |
Direct buses 3 |
Fastest bus 5h 50m |
First bus 12:15 AM |
Last bus 11:45 PM |
Cheapest Month May |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Tue |
Best time to book 42 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €21
Chicago, IL to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:15AM | Arrival Time 06:20AM | Duration 6h05 | Departure days Mon, Thu, Sat | Cheapest price €44 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 03:40PM | Duration 5h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €47 |
Operator Greyhound | Departure Time 10:15AM | Arrival Time 11:15PM | Duration 13h00 | Departure days Tue | Cheapest price €63 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 11:15PM | Duration 8h30 | Departure days Everyday | Cheapest price €58 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 11:20PM | Duration 6h15 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €44 |
Operator Greyhound | Departure Time 10:50PM | Arrival Time 07:55AM | Duration 9h05 | Departure days Everyday | Cheapest price €60 |
Operator Greyhound | Departure Time 11:10PM | Arrival Time 07:55AM | Duration 8h45 | Departure days Everyday | Cheapest price €60 |
Live departures
Chicago, IL to St. Louis, MO bus times
The table below shows live departures for Chicago, IL to St. Louis, MO buses for today, Wednesday, October 7. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · | 10:50 PM Chicago, Greyhound Bus Station | 9h05 | 7:55 AM St. Louis, S 15th St (Civic center) | 1 transfer | |
| · | 11:10 PM Chicago, Union Station (Amtrak), IL | 8h45 | 7:55 AM St. Louis, S 15th St (Civic center) | 1 transfer | |
| Thursday, October 8 | |||||
| FlixBus | 12:15 AM Chicago, Greyhound Bus Station | 6h05 | 6:20 AM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| FlixBus | 9:45 AM Chicago, Greyhound Bus Station | 5h55 | 3:40 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| · | 2:45 PM Chicago, Greyhound Bus Station | 8h30 | 11:15 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
| FlixBus | 5:05 PM Chicago, Greyhound Bus Station | 6h15 | 11:20 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Chicago, IL to St. Louis, MO buses with Omio?
Greyhound as well as FlixBus offer buses services from Chicago, IL to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Chicago, IL to St. Louis, MO.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Chicago, IL to St. Louis, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Chicago, IL to St. Louis, MO.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Chicago, IL to St. Louis, MO.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Chicago, IL to St. Louis, MO.
Bus providers: Greyhound, FlixBus from Chicago, IL to St. Louis, MOYou can travel by bus between Chicago, IL to St. Louis, MO with Greyhound, FlixBus for as low as €21. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
5h 50m
Cheapest FlixBus Price
€23
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
6h 50m
Cheapest Greyhound Price
€31
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to St. Louis, MO
Things to do in St. Louis, MO
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
- Recommended
Missouri History Museum
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
- Recommended
Saint Louis Science Center
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
- Must visit
Gateway Arch National Park Grounds
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
- Must visit
Forest Park
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
- Recommended
Tower Grove Park
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
- Vegetarian
St. Louis-Style Pizza
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
- Vegetarian
Toasted Ravioli
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
- Vegetarian
Gooey Butter Cake
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Bulrush
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Ted Drewes Frozen Custard
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Pappy's Smokehouse
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
United States dollar ($)
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-35 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $3-5 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
FAQs: Bus from Chicago, IL to St. Louis, MO
Find answers to the most common questions about traveling from Chicago, IL to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Chicago, IL to St. Louis, MO can start from as little as €23 when you book in advance. The average bus ticket price for Chicago, IL to St. Louis, MO is €56 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Chicago, IL to St. Louis, MO is 5h 50m to travel the 260 miles (419 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Chicago, IL to St. Louis, MO leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Chicago, IL to St. Louis, MO leaves at 11:45 PM.
Yes, there are 3 direct buses a day from Chicago, IL to St. Louis, MO with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Chicago, IL to St. Louis, MO, you can count on Greyhound, FlixBus for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Chicago, IL and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
When departing from Chicago, IL , you have various bus station options to start your journey from including Chicago, Greyhound Bus Station, Chicago, Union Station (Amtrak), IL, Chicago, 95th Red Line Station . When arriving in St. Louis, MO , you can end your journey in bus stations like St. Louis, S 15th St (Civic center) .Passengers board the bus most frequently from Chicago, Greyhound Bus Station, which is located around 1 miles (2 km) away from the city centre, and they get off the bus at St. Louis, S 15th St (Civic center), located 0 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between Chicago, IL and St. Louis, MO including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Chicago, IL to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Chicago, IL to St. Louis, MO for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Chicago, IL to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Chicago, IL to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Chicago, IL to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Chicago, IL to St. Louis, MO:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Chicago, IL to St. Louis, MO. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Chicago, IL to St. Louis, MO with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Chicago, IL to St. Louis, MO with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Chicago, IL to St. Louis, MO with the following bus company: Greyhound, FlixBus.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Chicago, IL to St. Louis, MO
Most Chicago, IL to St. Louis, MO buses use the Chicago, Greyhound Bus Station to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Chicago, IL and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Chicago
Arrival bus stations in St. Louis
Which Chicago, IL station do buses to St. Louis, MO leave from?
Buses from Chicago, IL to St. Louis, MO leave from Chicago, Greyhound Bus Station. The station is 1 miles (3 km) from Chicago, IL city centre at 630 W Harrison St, Chicago, IL 60607, USA.
Chicago, Greyhound Bus Station630 W Harrison St, Chicago, IL 60607, USA
City-centre transport
Getting to Chicago, Greyhound Bus Station from Chicago city centre
Chicago, Greyhound Bus Station is 2 km from Chicago city centre. Public transport options include:
Bus7 · 8m · €3 · every ~6 min
Chicago, Greyhound Bus Station bus station facilities and services
Chicago, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Snack shop and vending machines available
Wi-Fi and ATMs
Free Wi-Fi in waiting area. ATMs are located near entrance.
Tickets and information
Ticket office support is available at Chicago, Greyhound Bus Station.
Parking, taxis and toilets
Available at Chicago, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Greyhound Bus Station: Wheelchair accessible entrances and seating.
Chicago, Union Station (Amtrak)Chicago Union Station, 225 S Canal St, Chicago, IL 60606, USA
City-centre transport
Getting to Chicago, Union Station (Amtrak) from Chicago city centre
Chicago, Union Station (Amtrak) is 3 km from Chicago city centre. Public transport options include:
Bus28, 151 · 7m · €3 · every ~13 min
Chicago, Union Station (Amtrak) bus station facilities and services
Chicago, Union Station (Amtrak) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Multiple dining options are available inside the station.
Wi-Fi and ATMs
Free Wi-Fi is available in waiting areas. ATMs are aTMs are located near the main entrance.
Tickets and information
Ticket office support is available at Chicago, Union Station (Amtrak).
Parking, taxis and toilets
Available at Chicago, Union Station (Amtrak): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Union Station (Amtrak): Station is accessible with elevators and ramps.
Chicago, 95th Red Line Station95th Red Line Station, Chicago, IL 60620, USA
City-centre transport
Getting to Chicago, 95th Red Line Station from Chicago city centre
Chicago, 95th Red Line Station is 14 km from Chicago city centre. Public transport options include:
BusGreyhound US0100 · 20m · €2
29 · 47m · €3 · every ~11 min
29 · 48m · €3 · every ~11 min
SubwayRed Line · 24m · €5 · every ~23 min
Red Line · 25m · €5 · every ~23 min
Chicago, 95th Red Line Station bus station facilities and services
Chicago, 95th Red Line Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Chicago, 95th Red Line Station. ATMs are available at Chicago, 95th Red Line Station.
Tickets and information
Ticket office support is available at Chicago, 95th Red Line Station.
Parking, taxis and toilets
Available at Chicago, 95th Red Line Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, 95th Red Line Station: Wheelchair accessible entrances available.
Which St. Louis, MO station do buses from Chicago, IL arrive at?
Buses from Chicago, IL to St. Louis, MO arrive at St. Louis, S 15th St (Civic center). St. Louis, S 15th St (Civic center) is 0 miles (1 km) from St. Louis, MO city centre.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · €3 · every ~14 min
Bus19, 32, 40 · 8m · €1 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Most popular bus connections from Chicago, IL
More options for your journey from Chicago, IL to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Chicago, IL
Most popular bus connections to St. Louis, MO
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