4.9
4.6The cheapest and fastest buses from Chicago, IL to St. Louis, MO
Cheapest price
$81
Average price
$123
Fastest journey
6 h
Average duration
7 h 12 m
Buses per day
6
Distance
419 km
The best way to find a cheap bus ticket from Chicago, IL to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Chicago, IL to St. Louis, MO will cost around $123 if you buy it on the day, but the cheapest tickets can be found for only $81.
Of the 6 buses that leave Chicago, IL for St. Louis, MO on Tue, Nov 25, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Nov 25 the direct buses cover the 419 km distance in an average of 7 h 12 m but if you time it right, some buses will get you there in just 6 h .
On Tue, Nov 25 the slowest buses will take 8 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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Travel Information
Compare train, bus, and flight for Chicago, IL to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Chicago, IL to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from €40. For those with little time consider booking a flight which can get you there in 1h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €40, and a flight costs an average of €288.
Distance: 260 miles (419 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€51 Average price Cheapest | €58 Average price | €301 Average price |
6h 48m Average total duration 6h 18m Onboard + 30m Additional time* | 5h 29m Average total duration 4h 59m Onboard + 30m Additional time* | 4h 19m Average total duration Fastest 1h 19m Onboard + 3h 0m Additional time* |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.5kg CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Chicago, IL to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:15AM | Arrival Time 06:25AM | Duration 6h10 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $61 |
Operator Greyhound | Departure Time 06:10AM | Arrival Time 03:20PM | Duration 9h10 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $80 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 03:45PM | Duration 6h00 | Departure days Everyday | Cheapest price $72 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 11:10PM | Duration 6h40 | Departure days Everyday | Cheapest price $59 |
Operator Greyhound | Departure Time 09:40PM | Arrival Time 06:25AM | Duration 8h45 | Departure days Everyday | Cheapest price $89 |
Operator Greyhound | Departure Time 10:00PM | Arrival Time 06:25AM | Duration 8h25 | Departure days Everyday | Cheapest price $89 |
Live departures
Chicago, IL to St. Louis, MO bus times
The table below shows live departures for Chicago, IL to St. Louis, MO buses for today, Monday, November 24. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus | 3:45 PM Chicago, Greyhound Bus Station | 6h00 | 9:45 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| FlixBus | 10:30 PM Chicago, Greyhound Bus Station | 6h40 | 5:10 AM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| Tuesday, November 25 | |||||
| undefined · undefined | 3:40 AM Chicago, Greyhound Bus Station | 8h45 | 12:25 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
| undefined · undefined | 4:00 AM Chicago, Union Station (Amtrak), IL | 8h25 | 12:25 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
| FlixBus | 6:15 AM Chicago, Greyhound Bus Station | 6h10 | 12:25 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| undefined · undefined | 12:10 PM Chicago, Greyhound Bus Station | 9h10 | 9:20 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Chicago, IL to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Nov 30
Dec 01
Journey information
Overview: Bus from Chicago, IL to St. Louis, MO
USAUSA
Buses from Chicago, IL to St. Louis, MO run on average 5 times per day, taking around 6h 18m. Cheap bus tickets for this journey start at $50 (€40) but you can travel from only $44 (€35) by train.
There are 2 buses per day. The earliest bus runs at 00:15, the last at 23:45. The fastest bus covers the 260 miles (419 km) distance in 6h 0m.
Distance 260 miles (419 km) |
Average bus duration 6h 18m |
Cheapest ticket price $50 (€40) |
Buses per day 5 |
Direct buses 2 |
Fastest bus 6h 0m |
First bus 00:15 |
Last bus 23:45 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Chicago, IL to St. Louis, MO start from as low as $50 (€40) if booked well in advance.
- Standard Fares: Typically, trains cost $62 (€51) depending on the train type and class.
Journey Duration & Frequency
- On average there are 5 daily trains from Chicago, IL to St. Louis, MO with 2 direct service.
- The fastest trains can take as little as 6h 0m but the average duration is 6h 18m
Train Operators
- Travel from Chicago, IL to St. Louis, MO with Greyhound and FlixBus
- The most booked train company for this route on Omio is Greyhound.
Stations & Schedule
- Most trains depart from Chicago, Greyhound Bus Station and arrive in St. Louis, S 15th St (Civic center)
- First train typically departs at 12:15 AM and the last at 11:45 PM
Bus providers: Greyhound, FlixBus from Chicago, IL to St. Louis, MOYou can travel by bus between Chicago, IL to St. Louis, MO with Greyhound, FlixBus for as low as $44 (€35). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Chicago, IL to St. Louis, MO
Find answers to the most common questions about traveling from Chicago, IL to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Chicago, IL to St. Louis, MO, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Chicago, IL to St. Louis, MO
Most popular bus connections from Chicago, IL
More options for your journey from Chicago, IL to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Chicago, IL
Most popular bus connections to St. Louis, MO
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