- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Cheapest price on Sep 06
$121
Average ticket price on Sep 06
$126
Fastest journey on Sep 06
1 d 20 m
Average journey duration on Sep 06
1 d 1 h 13 m
Buses on Sep 06
9
Distance
1387 km
The best way to find a cheap bus ticket from Tampa, FL to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Tampa, FL to St. Louis, MO will cost around $126 if you buy it on the day, but the cheapest tickets can be found for only $121.
It's difficult to get from Tampa, FL to St. Louis, MO without transferring at least once.
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Omio recommends booking the bus as it is the most popular option from Tampa, FL to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $167 For those with little time, consider booking a flight, which has an average total journey time of 7h 12m. Average ticket prices depend on the travel mode: a bus costs an average of $167, while a flight costs an average of $477.
Distance: 861 miles (1387 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$167 Average price Cheapest | $363 Average price | $477 Average price | $209 Average price (fuel + tolls) |
24h 33m Average total duration 24h 3m Onboard + 30m Additional time* | 46h 33m Average total duration 46h 3m Onboard + 30m Additional time* | 7h 12m Average total duration Fastest 5h 12m Onboard + 2h 0m Additional time* | 14h 37m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Tampa, FL to St. Louis, MO:
A bus is $196 (€158) less than a train for this route with tickets for a train from Tampa, FL to St. Louis, MO costing on average $363 (€293).
A bus is $310 (€250) less than a flight for this route with tickets for a flight from Tampa, FL to St. Louis, MO costing on average $477 (€385).
Other travel options to St. Louis, MO take longer:
Bus takes on average 24h 3m.
Train takes on average 46h 3m.
Tickets start at around $167 (€135) compared to roughly $209 (€169) in fuel and tolls — a saving of about $42 (€34). The journey takes 24h 3m versus 14h 37m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:10AM | Arrival Time 10:15PM | Duration 41h05 | Departure days Everyday | Cheapest price $99 |
Operator Greyhound | Departure Time 06:20AM | Arrival Time 03:10PM | Duration 33h50 | Departure days Tue | Cheapest price $106 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 09:20AM | Duration 27h30 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $98 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 02:15PM | Duration 28h05 | Departure days Everyday | Cheapest price $99 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 03:55PM | Duration 24h55 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $103 |
Operator FlixBus | Departure Time 04:35PM | Arrival Time 03:55PM | Duration 24h20 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $103 |
Operator FlixBus | Departure Time 04:55PM | Arrival Time 03:55PM | Duration 24h00 | Departure days Tue | Cheapest price $107 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 03:55PM | Duration 23h30 | Departure days Tue | Cheapest price $108 |
Operator Greyhound | Departure Time 09:35PM | Arrival Time 09:30PM | Duration 24h55 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $96 |
Operator Greyhound | Departure Time 10:05PM | Arrival Time 09:30PM | Duration 24h25 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $96 |
Operator Greyhound | Departure Time 10:25PM | Arrival Time 09:20AM | Duration 35h55 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $103 |
Operator Greyhound | Departure Time 10:35PM | Arrival Time 09:20AM | Duration 35h45 | Departure days Everyday | Cheapest price $103 |
The table below shows live departures for Tampa, FL to St. Louis, MO buses for today, Saturday, September 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · · | 6:10 AM Tampa, Marion Transit Center | 41h05 | 10:15 PM St. Louis, Lambert International Airport | 4 transfers | |
+ FlixBus · FlixBus | 6:50 AM Tampa, Marion Transit Center | 27h30 | 9:20 AM St. Louis, S 15th St (Civic center) | 2 transfers | |
+ FlixBus+ + FlixBus | 11:10 AM Tampa, Marion Transit Center | 28h05 | 2:15 PM St. Louis, S 15th St (Civic center) | 3 transfers | |
FlixBus · FlixBus+ · | 4:00 PM Tampa, Marion Transit Center | 24h55 | 3:55 PM St. Louis, S 15th St (Civic center) | 3 transfers | |
FlixBus · FlixBus+ · | 4:35 PM Tampa, USF Holly Drive (Central Plant), FL | 24h20 | 3:55 PM St. Louis, S 15th St (Civic center) | 3 transfers |
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Tampa, FL to St. Louis, MO run on average 7 times per day, taking around 24h 3m. Cheap bus tickets for this journey start at $108 (€87) if you book in advance.
The earliest bus runs at 00:55, the last at 23:45. The fastest bus covers the 861 miles (1387 km) distance in 19h 40m.
Distance 861 miles (1387 km) |
Average bus duration 24h 3m |
Cheapest ticket price $108 (€87) |
Buses per day 7 |
Fastest bus 19h 40m |
First bus 12:55 AM |
Last bus 11:45 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 28 days |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Find answers to the most common questions about traveling from Tampa, FL to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Tampa, FL to St. Louis, MO buses use the Tampa, Marion Transit Center to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis, Lambert International Airport. Use this guide to compare Tampa, FL and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Tampa, Marion Transit Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Tampa, Marion Transit Center. ATMs are available at Tampa, Marion Transit Center.
Ticket office support is available at Tampa, Marion Transit Center.
Available at Tampa, Marion Transit Center: Parking, Taxis, WC.
Accessibility facilities are available at Tampa, Marion Transit Center: Wheelchair accessible with ramps.
Tampa, USF Holly Drive (Central Plant) is 13 km from Tampa city centre. Public transport options include:
Tampa, USF Holly Drive (Central Plant) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Tampa, USF Holly Drive (Central Plant). ATMs are available at Tampa, USF Holly Drive (Central Plant).
Ticket office support is available at Tampa, USF Holly Drive (Central Plant).
Available at Tampa, USF Holly Drive (Central Plant): Parking, Taxis, WC.
Accessibility facilities are available at Tampa, USF Holly Drive (Central Plant): Wheelchair accessible facilities.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple dining options available in terminals.
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Ticket office support is available at St. Louis, Lambert International Airport.
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
Here are some other resources that might have the information you need