- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Cheapest price on Sep 05
Kč2524
Average ticket price on Sep 05
Kč2646
Fastest journey on Sep 05
20 h 45 m
Average journey duration on Sep 05
22 h 41 m
Buses on Sep 05
7
Distance
1276 km
The best way to find a cheap bus ticket from San Antonio, TX to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to St. Louis, MO will cost around Kč2646 if you buy it on the day, but the cheapest tickets can be found for only Kč2524.
It's difficult to get from San Antonio, TX to St. Louis, MO without transferring at least 2 times.
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· Omio recommends booking the train as it is the most popular option from San Antonio, TX to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of Kč2915 For those with little time, consider booking a flight, which has an average total journey time of 6h 42m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.4 - 1.1kg. Average ticket prices depend on the travel mode: a bus costs an average of Kč2915, while a flight costs an average of Kč6161.
Distance: 792 miles (1276 km)
| Bus | Most popular Train | Flight |
|---|---|---|
Kč2915 Average price Cheapest | Kč3738 Average price | Kč6161 Average price |
21h 42m Average total duration 21h 12m Onboard + 30m Additional time* | 25h 36m Average total duration 25h 6m Onboard + 30m Additional time* | 6h 42m Average total duration Fastest 4h 42m Onboard + 2h 0m Additional time* |
1.3 - 3.2kg CO2 emissions | 0.4 - 1.1kg CO2 emissions Lowest | 3.8 - 7.7kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from San Antonio, TX to St. Louis, MO:
A bus is Kč822 less than a train for this route with tickets for a train from San Antonio, TX to St. Louis, MO costing on average Kč3738.
A bus is Kč3246 less than a flight for this route with tickets for a flight from San Antonio, TX to St. Louis, MO costing on average Kč6161.
Other travel options to St. Louis, MO take longer:
Bus takes on average 21h 12m.
Train takes on average 25h 6m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:30AM | Arrival Time 10:45PM | Duration 21h15 | Departure days Everyday | Cheapest price Kč2292 |
Operator Greyhound | Departure Time 07:30AM | Arrival Time 07:10AM | Duration 23h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price Kč2447 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 07:10AM | Duration 23h25 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price Kč2447 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 12:55PM | Duration 24h20 | Departure days Everyday | Cheapest price Kč2318 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 10:45PM | Duration 25h45 | Departure days Wed, Thu | Cheapest price Kč2344 |
Operator Greyhound | Departure Time 09:55PM | Arrival Time 10:15PM | Duration 24h20 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price Kč2486 |
The table below shows live departures for San Antonio, TX to St. Louis, MO buses for today, Friday, September 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ · | 9:55 PM San Antonio, N St Mary's St (Greyhound), TX | 24h20 | 10:15 PM St. Louis, Lambert International Airport | 2 transfers | |
FlixBus+ · | 9:55 PM San Antonio, N St Mary's St (Greyhound), TX | 24h50 | 10:45 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
| Saturday, September 5 | |||||
· · | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 21h15 | 10:45 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
· · | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 20h45 | 10:15 PM St. Louis, Lambert International Airport | 2 transfers | |
FlixBus · FlixBus+![]() | 7:30 AM San Antonio, N St Mary's St (Greyhound), TX | 23h40 | 7:10 AM St. Louis, S 15th St (Civic center) | 2 transfers | |
FlixBus · FlixBus+![]() | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 23h25 | 7:10 AM St. Louis, S 15th St (Civic center) | 2 transfers | |
· · | 12:35 PM San Antonio, N St Mary's St (Greyhound), TX | 24h20 | 12:55 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from San Antonio, TX to St. Louis, MO run on average 6 times per day, taking around 21h 12m. Cheap bus tickets for this journey start at Kč2202 if you book in advance.
The earliest bus runs at 01:00, the last at 23:45. The fastest bus covers the 792 miles (1276 km) distance in 20h 45m.
Distance 792 miles (1276 km) |
Average bus duration 21h 12m |
Cheapest ticket price Kč2202 |
Buses per day 6 |
Fastest bus 20h 45m |
First bus 1:00 AM |
Last bus 11:45 PM |
Cheapest Month Jun |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 3 days |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Find answers to the most common questions about traveling from San Antonio, TX to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most San Antonio, TX to St. Louis, MO buses use the San Antonio, N St Mary's St (Greyhound) to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis, Lambert International Airport. Use this guide to compare San Antonio, TX and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple dining options available in terminals.
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Ticket office support is available at St. Louis, Lambert International Airport.
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
Here are some other resources that might have the information you need