- Must visit
Saint Louis Art Museum
Major art museum in Forest Park with strong collections spanning ancient to contemporary works. A top cultural stop in the city.
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The cheapest and fastest buses from Philadelphia, PA to St. Louis, MO
Showing times and prices for Jun 10
Cheapest price
$123
Average price
$123
Fastest journey
22 h 50 m
Average duration
22 h 50 m
Buses per day
1
Distance
1301 km
Cheap tickets
The best way to find a cheap bus ticket from Philadelphia, PA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Philadelphia, PA to St. Louis, MO will cost around $123 if you buy it on the day, but the cheapest tickets can be found for only $123.
Fast buses
Of the 1 buses that leave Philadelphia, PA for St. Louis, MO on Wed, Jun 10, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jun 10 the direct buses cover the 1301 km distance in an average of 22 h 50 m but if you time it right, some buses will get you there in just 22 h 50 m .
On Wed, Jun 10 the slowest buses will take 22 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
9:30 PM22h50Philadelphia, PA8:20 PMSt. Louis, MO$1231One-way0 transfers
- 9:30 PM22h50Philadelphia, PA8:20 PMSt. Louis, MO$1231One-way0 transfers
Travel Information
Compare bus, train, and flight for Philadelphia, PA to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Philadelphia, PA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $96. For those with little time consider booking a flight which can get you there in 2h 23m. The ticket price range depends on the travel mode: a bus costs an average of $96, and a flight costs an average of $154.
Distance: 808 miles (1301 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$148 Average price Cheapest | $346 Average price | $492 Average price | $258 Average price (fuel + tolls) |
22h 27m Average total duration 21h 57m Onboard + 30m Additional time* | 24h 2m Average total duration 23h 32m Onboard + 30m Additional time* | 5h 23m Average total duration Fastest 2h 23m Onboard + 3h 0m Additional time* | 14h 7m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Philadelphia, PA to St. Louis, MO is a bus with an average price of $148 (€121).
This is compared to other travel options from Philadelphia, PA to St. Louis, MO:
A bus is $197 (€161) less than a train for this route with tickets for a train from Philadelphia, PA to St. Louis, MO costing on average $346 (€281).
A bus is $343 (€280) less than a flight for this route with tickets for a flight from Philadelphia, PA to St. Louis, MO costing on average $492 (€400).
The fastest way to travel from Philadelphia, PA to St. Louis, MO is by flight with an average journey time of 2h 23m.
Other travel options to St. Louis, MO take longer:
Bus takes on average 21h 57m.
Train takes on average 23h 32m.
It's helpful to compare your options as there are 3 ways to travel between Philadelphia, PA and St. Louis, MO including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Philadelphia, PA to St. Louis, MO among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $148 (€121) compared to roughly $258 (€210) in fuel and tolls — a saving of about $110 (€89). The journey takes 21h 57m versus 14h 7m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Philadelphia, PA to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 11:15PM | Duration 20h50 | Departure days Sun | Cheapest price $133 |
Operator FlixBus | Departure Time 03:55AM | Arrival Time 04:45AM | Duration 24h50 | Departure days Wed | Cheapest price $212 |
Operator Greyhound | Departure Time 12:05PM | Arrival Time 07:55AM | Duration 20h50 | Departure days Sun | Cheapest price $120 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 05:25AM | Duration 37h25 | Departure days Mon | Cheapest price $226 |
Operator Greyhound | Departure Time 04:05PM | Arrival Time 12:55PM | Duration 20h50 | Departure days Fri | Cheapest price $103 |
Operator Greyhound | Departure Time 05:35PM | Arrival Time 03:10PM | Duration 22h35 | Departure days Sun | Cheapest price $120 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 08:20PM | Duration 22h50 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $96 |
Operator Greyhound | Departure Time 09:35PM | Arrival Time 08:10PM | Duration 22h35 | Departure days Mon, Tue, Fri, Sat | Cheapest price $117 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 09:20PM | Duration 22h50 | Departure days Tue, Thu, Fri, Sat | Cheapest price $130 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 11:15PM | Duration 24h20 | Departure days Sun | Cheapest price $117 |
Live departures
Philadelphia, PA to St. Louis, MO bus times
The table below shows live departures for Philadelphia, PA to St. Louis, MO buses for today, Tuesday, June 9. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 3:55 AM Philadelphia, PA | 24h50 | 4:45 AM St. Louis, MO | 0 transfersDirect | |
| 9:30 PM Philadelphia, PA | 22h50 | 8:20 PM St. Louis, MO | 0 transfersDirect | |
| 9:35 PM Philadelphia, PA | 22h35 | 8:10 PM St. Louis, MO | 0 transfersDirect | |
| 10:30 PM Philadelphia, PA | 22h50 | 9:20 PM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Philadelphia, PA to St. Louis, MO by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Philadelphia, PA to St. Louis, MO buses with Omio?
Greyhound operates all buses services from Philadelphia, PA to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Philadelphia, PA to St. Louis, MO.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Philadelphia, PA to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Philadelphia, PA to St. Louis, MO.
Journey information
Overview: Bus from Philadelphia, PA to St. Louis, MO
USAUSA
Buses from Philadelphia, PA to St. Louis, MO run on average 12 times per day, taking around 21h 57m. Cheap bus tickets for this journey start at $96 (€78) if you book in advance.
There are 3 buses per day. The earliest bus runs at 01:00, the last at 23:55. The fastest bus covers the 808 miles (1301 km) distance in 20h 50m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 808 miles (1301 km) |
Average bus duration 21h 57m |
Cheapest ticket price $96 (€78) |
Buses per day 12 |
Direct buses 3 |
Fastest bus 20h 50m |
First bus 1:00 AM |
Last bus 11:55 PM |
Cheapest Month Oct |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Sun |
Best time to book 21 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Philadelphia, PA to St. Louis, MOYou can travel by bus between Philadelphia, PA to St. Louis, MO with Greyhound for as low as $96 (€78). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
20h 50m
Cheapest Price
$96 (€78)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to St. Louis
Things to do in St. Louis
Discover the best of St. Louis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis trip today.
- Must visit
City Museum
Highly original artist-built museum and playground with architectural salvage, tunnels, slides, and installations. One of St. Louis's most famous attractions.
- Recommended
Missouri History Museum
History museum in Forest Park covering St. Louis, Missouri, and regional stories through permanent and rotating exhibitions.
- Must visit
Forest Park
Huge urban park with museums, trails, lakes, and major attractions. One of the city's essential places for walking and relaxing.
- Recommended
Laclede's Landing
Historic riverfront district with cobblestone streets, old warehouses, and easy access to the Arch and Mississippi views.
- Recommended
Delmar Loop
Popular entertainment and walking district known for public art, music history, shops, and a lively street atmosphere.
- Vegetarian
St. Louis-Style Pizza
A local pizza style with a very thin, cracker-like crust, square-cut slices, and signature Provel cheese. It is one of the city’s most recognizable comfort foods.
Toasted Ravioli
Breaded and fried ravioli, usually filled with meat or cheese and served with marinara. Despite the name, it is fried, not toasted, and is a classic St. Louis starter.
- Vegetarian
Gooey Butter Cake
A rich, sweet cake with a dense, buttery topping over a soft base. It is a beloved St. Louis dessert found in bakeries across the city.
Pappy's Smokehouse
Popular barbecue restaurant known for Memphis-style ribs, pulled pork, and smoky sides in a lively, casual setting.
Ted Drewes Frozen Custard
Historic St. Louis dessert stand famous for frozen custard concretes and a nostalgic roadside feel.
Sidney Street Cafe
Established fine-dining restaurant serving refined American cuisine in a polished but welcoming atmosphere.
United States Dollar
St. Louis is generally affordable by U.S. city standards, with moderate hotel and restaurant prices and many low-cost attractions.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 20-40 per person at a casual sit-down restaurant.
- Fine dining
- USD 75+ per person at upscale restaurants.
- Coffee
- USD 4-6 for a latte or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 20%+ for great service. Tip bartenders USD 1-2 per drink, round up taxis, and tip hotel staff and delivery drivers.
FAQs: Bus from Philadelphia, PA to St. Louis, MO
Find answers to the most common questions about traveling from Philadelphia, PA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Philadelphia, PA to St. Louis, MO can start from as little as $96 (€78) when you book in advance. The average bus ticket price for Philadelphia, PA to St. Louis, MO is $148 (€121) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Philadelphia, PA to St. Louis, MO is 20h 50m to travel the 808 miles (1301 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Philadelphia, PA to St. Louis, MO leaves at 1:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Philadelphia, PA to St. Louis, MO leaves at 11:55 PM.
Yes, there are 3 direct buses a day from Philadelphia, PA to St. Louis, MO with Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Philadelphia, PA to St. Louis, MO, you can count on Greyhound for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Philadelphia, PA and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
A trip to St. Louis, MO from Philadelphia, PA is worth doing but not as a day trip with a journey time of 20h 50m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Philadelphia, PA to St. Louis, MO is October.
It's helpful to compare your options as there are 3 ways to travel between Philadelphia, PA and St. Louis, MO including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Philadelphia, PA to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Philadelphia, PA to St. Louis, MO for bus company Greyhound.
Whether you can cancel your bus ticket from Philadelphia, PA to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Philadelphia, PA to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Philadelphia, PA to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Philadelphia, PA to St. Louis, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Philadelphia, PA to St. Louis, MO.
You can reserve your seat on the bus from Philadelphia, PA to St. Louis, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Philadelphia, PA to St. Louis, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Philadelphia, PA to St. Louis, MO with the following bus company: Greyhound.
Since neither Philadelphia, PA nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Philadelphia, PA to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Philadelphia, PA to St. Louis, MO
Philadelphia
St. Louis
The major bus station for departures in Philadelphia is Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park). Find all the information you need to know about services, amenities and connections at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) for your trip from Philadelphia to St. Louis.
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park)
information
Philadelphia, Schuylkill Ave (Cira Centre South)
information
Philadelphia, Greyhound Bus Station
information
The major bus station for arrivals in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip to St. Louis from Philadelphia.
St. Louis, S 15th St (Civic center)
information
Most popular bus connections from Philadelphia, PA
More options for your journey from Philadelphia, PA to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Philadelphia, PA
Most popular bus connections to St. Louis, MO
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