4.9
4.6The cheapest and fastest buses from Philadelphia, PA to St. Louis, MO
Cheapest price
$121
Average price
$185
Fastest journey
20 h 30 m
Average duration
23 h 25 m
Buses per day
9
Distance
1301 km
The best way to find a cheap bus ticket from Philadelphia, PA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Philadelphia, PA to St. Louis, MO will cost around $185 if you buy it on the day, but the cheapest tickets can be found for only $121.
Of the 9 buses that leave Philadelphia, PA for St. Louis, MO on Wed, Mar 11, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Mar 11 the direct buses cover the 1301 km distance in an average of 23 h 25 m but if you time it right, some buses will get you there in just 20 h 30 m .
On Wed, Mar 11 the slowest buses will take 1 d 2 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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Travel Information
Compare bus, train, and flight for Philadelphia, PA to St. Louis, MO
Omio recommends booking the bus as it is the most popular option from Philadelphia, PA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $101. For those with little time consider booking a flight which can get you there in 2h 23m. The ticket price range depends on the travel mode: a bus costs an average of $101, and a flight costs an average of $252.
Distance: 808 miles (1301 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$151 Average price Cheapest | $276 Average price | $456 Average price |
22h 27m Average total duration 21h 57m Onboard + 30m Additional time* | 25h 39m Average total duration 25h 9m Onboard + 30m Additional time* | 5h 23m Average total duration Fastest 2h 23m Onboard + 3h 0m Additional time* |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Philadelphia, PA to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:55AM | Arrival Time 11:25PM | Duration 20h30 | Departure days Tue, Wed | Cheapest price $119 |
Operator Greyhound | Departure Time 05:00AM | Arrival Time 07:55AM | Duration 27h55 | Departure days Tue, Wed | Cheapest price $168 |
Operator Greyhound | Departure Time 06:00AM | Arrival Time 07:55AM | Duration 26h55 | Departure days Tue, Wed | Cheapest price $167 |
Operator Greyhound | Departure Time 12:05PM | Arrival Time 07:55AM | Duration 20h50 | Departure days Tue, Wed | Cheapest price $105 |
Operator Greyhound | Departure Time 01:45PM | Arrival Time 03:20PM | Duration 26h35 | Departure days Tue, Wed | Cheapest price $200 |
Operator Greyhound | Departure Time 02:00PM | Arrival Time 03:20PM | Duration 26h20 | Departure days Tue, Wed | Cheapest price $200 |
Operator Greyhound | Departure Time 05:30PM | Arrival Time 03:20PM | Duration 22h50 | Departure days Tue, Wed | Cheapest price $96 |
Operator Greyhound | Departure Time 06:30PM | Arrival Time 11:25PM | Duration 29h55 | Departure days Wed | Cheapest price $244 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 11:25PM | Duration 27h55 | Departure days Tue, Wed | Cheapest price $167 |
Operator Greyhound | Departure Time 10:00PM | Arrival Time 11:25PM | Duration 26h25 | Departure days Tue | Cheapest price $167 |
Live departures
Philadelphia, PA to St. Louis, MO bus times
The table below shows live departures for Philadelphia, PA to St. Louis, MO buses for today, Tuesday, March 10. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 7:55 AM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 20h30 | 4:25 AM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| FlixBus+undefined · undefined | 9:00 AM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 27h55 | 12:55 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
| +FlixBus+ | 10:00 AM Philadelphia, Schuylkill Ave (Cira Centre South), PA | 26h55 | 12:55 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
| 4:05 PM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 20h50 | 12:55 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| FlixBus+undefined · undefined | 5:45 PM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 26h35 | 8:20 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
| undefined · undefined · undefined | 6:00 PM Philadelphia, Schuylkill Ave (Cira Centre South), PA | 26h20 | 8:20 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
| 9:30 PM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 22h50 | 8:20 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| Wednesday, March 11 | |||||
| undefined · undefined · undefined | 12:30 AM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 27h55 | 4:25 AM St. Louis, S 15th St (Civic center) | 2 transfers | |
| FlixBus+undefined · undefined | 2:00 AM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 26h25 | 4:25 AM St. Louis, S 15th St (Civic center) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Philadelphia, PA to St. Louis, MO by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Philadelphia, PA to St. Louis, MO buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Philadelphia, PA to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Philadelphia, PA to St. Louis, MO.
Journey information
Overview: Bus from Philadelphia, PA to St. Louis, MO
USAUSA
Buses from Philadelphia, PA to St. Louis, MO run on average 13 times per day, taking around 21h 57m. Cheap bus tickets for this journey start at $101 (€82) if you book in advance.
There are 2 buses per day. The earliest bus runs at 01:00, the last at 23:30. The fastest bus covers the 808 miles (1301 km) distance in 20h 30m.
Distance 808 miles (1301 km) |
Average bus duration 21h 57m |
Cheapest ticket price $101 (€82) |
Buses per day 13 |
Direct buses 2 |
Fastest bus 20h 30m |
First bus 01:00 |
Last bus 23:30 |
Cheapest month Oct |
Cheapest day Tue |
High season Apr - Jun |
Low season Jan - Mar |
Busiest day Sun |
Least busy day Sun |
Best day to book ahead 21 days |
Bus providers: Greyhound from Philadelphia, PA to St. Louis, MOYou can travel by bus between Philadelphia, PA to St. Louis, MO with Greyhound for as low as $101 (€82). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Philadelphia, PA to St. Louis, MO
Find answers to the most common questions about traveling from Philadelphia, PA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Philadelphia, PA to St. Louis, MO
Most popular bus connections from Philadelphia, PA
More options for your journey from Philadelphia, PA to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Philadelphia, PA
Most popular bus connections to St. Louis, MO
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