- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Cheapest price on Oct 28
$115
Average ticket price on Oct 28
$140
Fastest journey on Oct 28
20 h 5 m
Average journey duration on Oct 28
23 h 5 m
Buses on Oct 28
4
Distance
1301 km
The best way to find a cheap bus ticket from Philadelphia, PA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Philadelphia, PA to St. Louis, MO will cost around $140 if you buy it on the day, but the cheapest tickets can be found for only $115.
On Wed, Oct 28, we found 4 buses from Philadelphia, PA to St. Louis, MO, including 3 direct services.
On Wed, Oct 28 the direct buses cover the 1301 km distance in an average of 23 h 5 m but if you time it right, some buses will get you there in just 20 h 5 m .
On Wed, Oct 28 the slowest buses will take 1 d 4 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.



· · 


· · Buses from Philadelphia, PA to St. Louis, MO run on average 5 times per day, taking around 21h 42m. Cheap bus tickets for this journey start at $78 if you book in advance.
There are 3 buses per day. The earliest bus runs at 01:00, the last at 23:55. The fastest bus covers the 808 miles (1301 km) distance in 20h 0m.
Distance 808 miles (1301 km) |
Average bus duration 21h 42m |
Cheapest ticket price $78 |
Buses per day 5 |
Direct buses 3 |
Fastest bus 20h 0m |
First bus 1:00 AM |
Last bus 11:55 PM |
Cheapest Month Oct |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 42 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Philadelphia, PA to St. Louis, MO.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:25AM | Arrival Time 10:15PM | Duration 20h50 | Departure days Sun | Cheapest price $113 |
Operator Greyhound | Departure Time 03:25AM | Arrival Time 11:15PM | Duration 20h50 | Departure days Mon, Tue, Thu, Fri, Sat | Cheapest price $80 |
Operator Greyhound | Departure Time 03:45AM | Arrival Time 10:50PM | Duration 20h05 | Departure days Wed | Cheapest price $141 |
Operator Greyhound | Departure Time 12:05PM | Arrival Time 07:55AM | Duration 20h50 | Departure days Everyday | Cheapest price $78 |
Operator Greyhound | Departure Time 05:35PM | Arrival Time 03:10PM | Duration 22h35 | Departure days Everyday | Cheapest price $78 |
Operator Greyhound | Departure Time 07:20PM | Arrival Time 10:50PM | Duration 28h30 | Departure days Wed | Cheapest price $172 |
Operator Greyhound | Departure Time 08:45PM | Arrival Time 11:15PM | Duration 27h30 | Departure days Thu | Cheapest price $108 |
Operator Greyhound | Departure Time 10:00PM | Arrival Time 11:15PM | Duration 26h15 | Departure days Tue, Fri | Cheapest price $90 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 10:15PM | Duration 24h20 | Departure days Mon, Sat, Sun | Cheapest price $103 |
The table below shows live departures for Philadelphia, PA to St. Louis, MO buses for today, Tuesday, October 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:05 PM Philadelphia Bus Station | 20h50 | 7:55 AM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
![]() | 5:35 PM Philadelphia Bus Station | 22h35 | 3:10 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
FlixBus+ · | 10:00 PM Philadelphia Bus Station | 26h15 | 11:15 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
| Wednesday, October 28 | |||||
![]() | 3:45 AM Philadelphia Bus Station | 20h05 | 10:50 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in St. Louis, MO.
Find answers to the most common questions about traveling from Philadelphia, PA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Philadelphia, PA to St. Louis, MO buses use the Philadelphia, Greyhound Bus Station to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Philadelphia, PA and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Philadelphia, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bars and vending machines are available.
Free Wi-Fi available in the waiting area. ATMs are an ATM is available near the entrance.
Ticket office support is available at Philadelphia, Greyhound Bus Station.
Available at Philadelphia, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Greyhound Bus Station: The station is wheelchair accessible with ramps and elevators.
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) is 2 km from Philadelphia city centre. Public transport options include:
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park). ATMs are available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park).
Ticket office support is available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park).
Available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park): Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park): The bus stop is accessible with ramps.
Philadelphia, Schuylkill Ave (Cira Centre South) is 1 km from Philadelphia city centre. Public transport options include:
Philadelphia, Schuylkill Ave (Cira Centre South) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available in the waiting area. ATMs are available at Philadelphia, Schuylkill Ave (Cira Centre South).
Ticket office support is available at Philadelphia, Schuylkill Ave (Cira Centre South).
Available at Philadelphia, Schuylkill Ave (Cira Centre South): Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Schuylkill Ave (Cira Centre South): Wheelchair accessible area.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Check bus stations information for Philadelphia, PA and St. Louis, MO, including where buses depart and arrive on this route.
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