- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Cheapest price on Sep 13
lei408
Average ticket price on Sep 13
lei484
Fastest journey on Sep 13
20 h 50 m
Average journey duration on Sep 13
22 h 38 m
Buses on Sep 13
4
Distance
1301 km
The best way to find a cheap bus ticket from Philadelphia, PA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Philadelphia, PA to St. Louis, MO will cost around lei484 if you buy it on the day, but the cheapest tickets can be found for only lei408.
On Sun, Sep 13, we found 4 buses from Philadelphia, PA to St. Louis, MO, including 3 direct services.
On Sun, Sep 13 the direct buses cover the 1301 km distance in an average of 22 h 38 m but if you time it right, some buses will get you there in just 20 h 50 m .
On Sun, Sep 13 the slowest buses will take 1 d 2 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.



FlixBus+
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FlixBus+
· Omio recommends booking the bus as it is the most popular option from Philadelphia, PA to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of lei761 For those with little time, consider booking a flight, which has an average total journey time of 6h 35m. Average ticket prices depend on the travel mode: a bus costs an average of lei761, while a flight costs an average of lei3096.
Distance: 808 miles (1301 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
lei761 Average price Cheapest | lei2604 Average price | lei3096 Average price | lei1181 Average price (fuel + tolls) |
22h 24m Average total duration 21h 54m Onboard + 30m Additional time* | 25h 47m Average total duration 25h 17m Onboard + 30m Additional time* | 6h 35m Average total duration Fastest 4h 35m Onboard + 2h 0m Additional time* | 14h 7m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Philadelphia, PA to St. Louis, MO:
A bus is lei1844 less than a train for this route with tickets for a train from Philadelphia, PA to St. Louis, MO costing on average lei2604.
A bus is lei2335 less than a flight for this route with tickets for a flight from Philadelphia, PA to St. Louis, MO costing on average lei3096.
Other travel options to St. Louis, MO take longer:
Bus takes on average 21h 54m.
Train takes on average 25h 17m.
Tickets start at around lei761 compared to roughly lei1181 in fuel and tolls — a saving of about lei420. The journey takes 21h 54m versus 14h 7m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 11:15PM | Duration 20h50 | Departure days Everyday | Cheapest price lei375 |
Operator Greyhound | Departure Time 12:05PM | Arrival Time 07:55AM | Duration 20h50 | Departure days Everyday | Cheapest price lei375 |
Operator Greyhound | Departure Time 05:35PM | Arrival Time 03:10PM | Duration 22h35 | Departure days Everyday | Cheapest price lei364 |
Operator Greyhound | Departure Time 07:20PM | Arrival Time 11:15PM | Duration 28h55 | Departure days Wed | Cheapest price lei764 |
Operator Greyhound | Departure Time 08:45PM | Arrival Time 11:15PM | Duration 27h30 | Departure days Thu | Cheapest price lei740 |
Operator Greyhound | Departure Time 10:00PM | Arrival Time 11:15PM | Duration 26h15 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price lei498 |
The table below shows live departures for Philadelphia, PA to St. Louis, MO buses for today, Saturday, September 12. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:25 AM Philadelphia Bus Station | 20h50 | 11:15 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
![]() | 12:05 PM Philadelphia Bus Station | 20h50 | 7:55 AM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
![]() | 5:35 PM Philadelphia Bus Station | 22h35 | 3:10 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Philadelphia, PA to St. Louis, MO run on average 6 times per day, taking around 21h 54m. Cheap bus tickets for this journey start at lei408 if you book in advance.
There are 3 buses per day. The earliest bus runs at 01:00, the last at 23:55. The fastest bus covers the 808 miles (1301 km) distance in 19h 35m.
Distance 808 miles (1301 km) |
Average bus duration 21h 54m |
Cheapest ticket price lei408 |
Buses per day 6 |
Direct buses 3 |
Fastest bus 19h 35m |
First bus 1:00 AM |
Last bus 11:55 PM |
Cheapest Month Oct |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 42 days |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Find answers to the most common questions about traveling from Philadelphia, PA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Philadelphia, PA to St. Louis, MO buses use the Philadelphia, Greyhound Bus Station to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Philadelphia, PA and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Philadelphia, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bars and vending machines are available.
Free Wi-Fi available in the waiting area. ATMs are an ATM is available near the entrance.
Ticket office support is available at Philadelphia, Greyhound Bus Station.
Available at Philadelphia, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Greyhound Bus Station: The station is wheelchair accessible with ramps and elevators.
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) is 2 km from Philadelphia city centre. Public transport options include:
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park). ATMs are available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park).
Ticket office support is available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park).
Available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park): Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park): The bus stop is accessible with ramps.
Philadelphia, Schuylkill Ave (Cira Centre South) is 1 km from Philadelphia city centre. Public transport options include:
Philadelphia, Schuylkill Ave (Cira Centre South) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available in the waiting area. ATMs are available at Philadelphia, Schuylkill Ave (Cira Centre South).
Ticket office support is available at Philadelphia, Schuylkill Ave (Cira Centre South).
Available at Philadelphia, Schuylkill Ave (Cira Centre South): Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Schuylkill Ave (Cira Centre South): Wheelchair accessible area.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Here are some other resources that might have the information you need