San Diego, CA to St. Louis, MO bus with Greyhound

Thu, Nov 06
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The cheapest and fastest buses from San Diego, CA to St. Louis, MO

Showing times and prices for Nov 06

Cheapest price

$713

Average price

$713

Fastest journey

2 d

Average duration

2 d 1 h 38 m

Buses per day

2

Distance

2512 km

Cheap tickets

The best way to find a cheap bus ticket from San Diego, CA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from San Diego, CA to St. Louis, MO will cost around $713 if you buy it on the day, but the cheapest tickets can be found for only $713.

Fast buses

It's difficult to get from San Diego, CA to St. Louis, MO without transferring at least once.

Greyhound Mexico
07:05AM48h00
San Diego, CA
07:05AMSt. Louis, MO
$7131One-way
1 transfer
Greyhound Mexico
07:25PM51h15
San Diego, CA
10:40PMSt. Louis, MO
$7131One-way
1 transfer

Travel Information

Compare train, bus, and flight for San Diego, CA to St. Louis, MO

Omio recommends booking the train as it is the most popular option from San Diego, CA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from €128. For those with little time consider booking a flight which can get you there in 7h 23m. The ticket price range depends on the travel mode: a bus costs an average of €128, and a flight costs an average of €253.

Distance: 1560 miles (2512 km)

Compare bus with

Bus
Most popular
Train
Flight

€188

Average price

Cheapest

€275

Average price

€276

Average price

46h 3m

Average total duration

45h 33m

Onboard

+

30m

Additional time*

46h 46m

Average total duration

46h 16m

Onboard

+

30m

Additional time*

10h 23m

Average total duration

Fastest

7h 23m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

San Diego, CA to St. Louis, MO Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
06:45AM
Arrival Time
07:10AM
Duration
46h25
Departure days
Wed
Cheapest price
$365
Operator
Greyhound
Departure Time
06:55AM
Arrival Time
07:10AM
Duration
46h15
Departure days
Wed
Cheapest price
$374
Operator
Greyhound
Departure Time
07:35AM
Arrival Time
07:10AM
Duration
45h35
Departure days
Wed
Cheapest price
$380
Operator
Greyhound
Departure Time
09:25AM
Arrival Time
12:55PM
Duration
49h30
Departure days
Wed
Cheapest price
$305
Operator
Greyhound
Departure Time
01:15PM
Arrival Time
12:55PM
Duration
45h40
Departure days
Wed
Cheapest price
$299
Operator
Greyhound
Departure Time
01:45PM
Arrival Time
12:55PM
Duration
45h10
Departure days
Wed
Cheapest price
$303

Live departures

San Diego, CA to St. Louis, MO bus times

The table below shows live departures for San Diego, CA to St. Louis, MO buses for tomorrow, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.

Last updated at 10:11 PM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound7:05 AM San Diego, CA
48h00
7:05 AM St. Louis, MO1 transfer
greyhound7:25 PM San Diego, CA
51h15
10:40 PM St. Louis, MO1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets San Diego, CA to St. Louis, MO by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
Nov 06
Fri
Nov 07
Sat
Nov 08
Sun
Nov 09
Mon
Nov 10
Tue
Nov 11
Wed
Nov 12

Journey information

Overview: Bus from San Diego, CA to St. Louis, MO

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Buses from San Diego, CA to St. Louis, MO run on average 13 times per day, taking around 45h 33m. Cheap bus tickets for this journey start at $157 (€128) if you book in advance.

The earliest bus runs at 00:55, the last at 23:30. The fastest bus covers the 1560 miles (2512 km) distance in 45h 30m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1560 miles (2512 km)
Average bus duration
45h 33m
Cheapest ticket price
$157 (€128)
Buses per day
13
Fastest bus
45h 30m
First bus
00:55
Last bus
23:30
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from San Diego, CA to St. Louis, MOYou can travel by bus between San Diego, CA to St. Louis, MO with Greyhound for as low as $157 (€128). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
44h 55m
Cheapest Price
$123 (€101)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from San Diego, CA to St. Louis, MO

Find answers to the most common questions about traveling from San Diego, CA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from San Diego, CA to St. Louis, MO can start from as little as $217 (€177) when you book in advance. The average bus ticket price for San Diego, CA to St. Louis, MO is $217 (€177); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The bus time from San Diego, CA to St. Louis, MO is on average 44 h 55 min   for the 1557 mile (2512 km) long journey, but the time it takes to go between San Diego, CA and St. Louis, MO by bus can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from San Diego, CA to St. Louis, MO leaves at 12: 40AM. Plan your trip with the Journey Planner   from Omio.
The last bus from San Diego, CA to St. Louis, MO leaves at 7: 35PM.
There are 17 buses a day from San Diego, CA to St. Louis, MO which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Diego, CA to St. Louis, MO, you can count on Greyhound for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between San Diego, CA and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
The cheapest month for a bus from San Diego, CA to St. Louis, MO is October.
You have options as you can travel to St. Louis, MO from San Diego, CA 2 different ways: train or bus.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to St. Louis, MO:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Diego, CA to St. Louis, MO for bus company Greyhound.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Whether you can cancel your bus ticket from San Diego, CA to St. Louis, MO depends on the bus company:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.

To find the cheapest bus tickets for your trip from San Diego, CA to St. Louis, MO, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from San Diego, CA to St. Louis, MO.
    Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to St. Louis, MO:
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to St. Louis, MO:
    • Greyhound
      • $15 per additional bag.
    Unfortunately, pets are not allowed on the bus from San Diego, CA to St. Louis, MO.
    You can reserve your seat on the bus from San Diego, CA to St. Louis, MO with the following bus company: Greyhound
    Yes, there are USB plugs on board the bus from San Diego, CA to St. Louis, MO with the following bus company: Greyhound.
    Yes, there is Wifi on board the bus from San Diego, CA to St. Louis, MO with the following bus company: Greyhound.

    popular bus stations

    Popular bus stations from San Diego, CA to St. Louis, MO

    San Diego
    St. Louis
    The major bus station for departures in San Diego is San Diego, San Ysidro Transit Center. Find all the information you need to know about services, amenities and connections at San Diego, San Ysidro Transit Center for your trip from San Diego to St. Louis.
    San Diego, San Ysidro Transit Center
    information
    San Diego, Congress Street (Old Town Park)
    information
    San Diego, West Harbor Drive (The Headquarters at Seaport District)
    information
    HomeBusesBuses in USABus tickets to St. Louis, MOSan Diego, CA to St. Louis, MO bus

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