4.9
4.6The cheapest and fastest buses from San Diego, CA to St. Louis, MO
Cheapest price
$536
Average price
$539
Fastest journey
2 d 10 m
Average duration
2 d 1 h 45 m
Buses per day
4
Distance
2512 km
The best way to find a cheap bus ticket from San Diego, CA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Diego, CA to St. Louis, MO will cost around $539 if you buy it on the day, but the cheapest tickets can be found for only $536.
It's difficult to get from San Diego, CA to St. Louis, MO without transferring at least once.
Travel Information
Compare train, bus, and flight for San Diego, CA to St. Louis, MO
Omio recommends booking the train as it is the most popular option from San Diego, CA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $174. For those with little time consider booking a flight which can get you there in 7h 56m. The ticket price range depends on the travel mode: a bus costs an average of $174, and a train costs an average of $299.
Distance: 1560 miles (2512 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$251 Average price Cheapest | $316 Average price | $266 Average price |
50h 35m Average total duration 50h 5m Onboard + 30m Additional time* | 46h 46m Average total duration 46h 16m Onboard + 30m Additional time* | 10h 56m Average total duration Fastest 7h 56m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
San Diego, CA to St. Louis, MO bus times
The table below shows live departures for San Diego, CA to St. Louis, MO buses for tomorrow, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 7:00 AM San Diego, CA | 48h10 | 7:10 AM St. Louis, MO | 2 transfers | |
| 7:00 AM San Diego, CA | 48h10 | 7:10 AM St. Louis, MO | 1 transfer | |
| 7:25 PM San Diego, CA | 51h20 | 10:45 PM St. Louis, MO | 2 transfers | |
| 7:25 PM San Diego, CA | 51h20 | 10:45 PM St. Louis, MO | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Diego, CA to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book San Diego, CA to St. Louis, MO buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Diego, CA to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Diego, CA to St. Louis, MO.
Journey information
Overview: Bus from San Diego, CA to St. Louis, MO
USAUSA
Buses from San Diego, CA to St. Louis, MO run on average 11 times per day, taking around 50h 5m. Cheap bus tickets for this journey start at $174 (€141) but you can travel from only $171 (€139) by flight.
The earliest bus runs at 01:15, the last at 23:30. The fastest bus covers the 1560 miles (2512 km) distance in 46h 15m.
Distance 1560 miles (2512 km) |
Average bus duration 50h 5m |
Cheapest ticket price $174 (€141) |
Buses per day 11 |
Fastest bus 46h 15m |
First bus 01:15 |
Last bus 23:30 |
Bus providers: Greyhound from San Diego, CA to St. Louis, MOYou can travel by bus between San Diego, CA to St. Louis, MO with Greyhound for as low as $171 (€139). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from San Diego, CA to St. Louis, MO
Find answers to the most common questions about traveling from San Diego, CA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from San Diego, CA to St. Louis, MO
More options for your journey from San Diego, CA to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and San Diego, CA
Most popular bus connections to St. Louis, MO
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
