- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Cheapest price
$147
Average price
$233
Fastest journey
1 d 4 h 50 m
Average duration
1 d 7 h 9 m
Buses per day
7
Distance
1667 km
The best way to find a cheap bus ticket from Boston, MA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Boston, MA to St. Louis, MO will cost around $233 if you buy it on the day, but the cheapest tickets can be found for only $147.
Of the 7 buses that leave Boston, MA for St. Louis, MO on Tue, Aug 25, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Aug 25 the direct buses cover the 1667 km distance in an average of 1 d 7 h 9 m but if you time it right, some buses will get you there in just 1 d 4 h 50 m .
On Tue, Aug 25 the slowest buses will take 1 d 11 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Omio recommends booking the train as it is the most popular option from Boston, MA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $120. For those with little time consider booking a flight which can get you there in 5h 22m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.5 - 1.5kg. The ticket price range depends on the travel mode: a bus costs an average of $120, and a train costs an average of $185.
Distance: 1035 miles (1667 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$223 Average price Cheapest | $938 Average price | $597 Average price | $304 Average price (fuel + tolls) |
30h 37m Average total duration 30h 7m Onboard + 30m Additional time* | 27h 39m Average total duration 27h 9m Onboard + 30m Additional time* | 8h 22m Average total duration Fastest 5h 22m Onboard + 3h 0m Additional time* | 17h 43m Average total duration (door-to-door) |
1.7 - 4.2kg CO2 emissions | 0.5 - 1.5kg CO2 emissions Lowest | 5.0 - 10.0kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Boston, MA to St. Louis, MO:
A bus is $374 less than a flight for this route with tickets for a flight from Boston, MA to St. Louis, MO costing on average $597.
A bus is $715 less than a train for this route with tickets for a train from Boston, MA to St. Louis, MO costing on average $938.
Other travel options to St. Louis, MO take longer:
Train takes on average 27h 9m.
Bus takes on average 30h 7m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:35AM | Arrival Time 05:25AM | Duration 28h50 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $135 |
Operator Greyhound | Departure Time 01:50AM | Arrival Time 12:55PM | Duration 35h05 | Departure days Wed, Thu, Fri, Sat | Cheapest price $244 |
Operator Greyhound | Departure Time 02:50AM | Arrival Time 01:55PM | Duration 35h05 | Departure days Wed, Sat | Cheapest price $266 |
Operator Greyhound | Departure Time 06:00AM | Arrival Time 07:45AM | Duration 26h45 | Departure days Mon | Cheapest price $164 |
Operator Greyhound | Departure Time 06:15AM | Arrival Time 12:55PM | Duration 30h40 | Departure days Thu, Fri, Sat, Sun | Cheapest price $123 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 12:55PM | Duration 30h25 | Departure days Sat, Sun | Cheapest price $114 |
Operator Greyhound | Departure Time 07:15AM | Arrival Time 01:55PM | Duration 30h40 | Departure days Thu, Sat | Cheapest price $234 |
Operator Greyhound | Departure Time 08:55AM | Arrival Time 03:10PM | Duration 31h15 | Departure days Mon | Cheapest price $146 |
Operator Greyhound | Departure Time 12:55PM | Arrival Time 08:20PM | Duration 31h25 | Departure days Tue, Wed, Thu, Sat | Cheapest price $171 |
Operator Greyhound | Departure Time 01:30PM | Arrival Time 09:20PM | Duration 31h50 | Departure days Fri | Cheapest price $331 |
Operator Greyhound | Departure Time 01:55PM | Arrival Time 09:20PM | Duration 31h25 | Departure days Tue, Wed, Thu, Fri | Cheapest price $147 |
Operator Greyhound | Departure Time 08:15PM | Arrival Time 11:15PM | Duration 28h00 | Departure days Mon | Cheapest price $210 |
Operator Greyhound | Departure Time 09:50PM | Arrival Time 07:45AM | Duration 34h55 | Departure days Mon | Cheapest price $208 |
Operator Greyhound | Departure Time 10:15PM | Arrival Time 03:15AM | Duration 53h00 | Departure days Tue, Thu | Cheapest price $184 |
Operator Greyhound | Departure Time 11:15PM | Arrival Time 04:15AM | Duration 53h00 | Departure days Sun | Cheapest price $151 |
Operator Greyhound | Departure Time 11:35PM | Arrival Time 04:45AM | Duration 29h10 | Departure days Tue, Wed, Fri, Sun | Cheapest price $162 |
The table below shows live departures for Boston, MA to St. Louis, MO buses for today, Monday, August 24. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 8:15 PM Boston, Bus Terminal South Station | 28h00 | 11:15 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
| Tuesday, August 25 | |||||
![]() | 12:35 AM Boston, MA | 28h50 | 5:25 AM St. Louis, MO | 0 transfersDirect | |
| Monday, August 24 | |||||
FlixBus+ · | 9:50 PM Boston, Bus Terminal South Station | 34h55 | 7:45 AM St. Louis, S 15th St (Civic center) | 2 transfers | |
| Tuesday, August 25 | |||||
![]() | 1:50 AM Boston, MA | 35h05 | 12:55 PM St. Louis, MO | 0 transfersDirect | |
![]() | 2:50 AM Boston, MA | 35h05 | 1:55 PM St. Louis, MO | 0 transfersDirect | |
![]() | 12:55 PM Boston, MA | 31h15 | 8:10 PM St. Louis, MO | 0 transfersDirect | |
![]() | 1:55 PM Boston, MA | 31h25 | 9:20 PM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Boston, MA to St. Louis, MO run on average 5 times per day, taking around 30h 7m. Cheap bus tickets for this journey start at $120 if you book in advance.
The earliest bus runs at 01:30, the last at 23:30. The fastest bus covers the 1035 miles (1667 km) distance in 25h 30m.
Distance 1035 miles (1667 km) |
Average bus duration 30h 7m |
Cheapest ticket price $120 |
Buses per day 5 |
Fastest bus 25h 30m |
First bus 1:30 AM |
Last bus 11:30 PM |
Cheapest Month Apr |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 4 days |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Find answers to the most common questions about traveling from Boston, MA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Boston, MA to St. Louis, MO buses use the Boston, Bus Terminal South Station to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis, Lambert International Airport. Use this guide to compare Boston, MA and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Boston, Bus Terminal South Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food and cafe options available.
Free Wi-Fi available throughout the terminal. ATMs are aTMs located inside the terminal.
Ticket office support is available at Boston, Bus Terminal South Station.
Available at Boston, Bus Terminal South Station: Parking, Taxis, WC.
Accessibility facilities are available at Boston, Bus Terminal South Station: Fully accessible with ramps and elevators.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple dining options available in terminals.
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Ticket office support is available at St. Louis, Lambert International Airport.
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
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