Boston, MA to St. Louis, MO bus with Greyhound

Tue, Aug 25
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The cheapest and fastest buses from Boston, MA to St. Louis, MO

Showing times and prices for Aug 25

Cheapest price

$147

Average price

$233

Fastest journey

1 d 4 h 50 m

Average duration

1 d 7 h 9 m

Buses per day

7

Distance

1667 km

Cheap tickets

The best way to find a cheap bus ticket from Boston, MA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Boston, MA to St. Louis, MO will cost around $233 if you buy it on the day, but the cheapest tickets can be found for only $147.

Fast buses

Of the 7 buses that leave Boston, MA for St. Louis, MO on Tue, Aug 25, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Tue, Aug 25 the direct buses cover the 1667 km distance in an average of 1 d 7 h 9 m but if you time it right, some buses will get you there in just 1 d 4 h 50 m .

On Tue, Aug 25 the slowest buses will take 1 d 11 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Greyhound
    1:55 PM31h25
    Boston, MA
    9:20 PMSt. Louis, MO
    $1471One-way
    0 transfers
  • Greyhound
    11:35 PM29h10
    Boston, MA
    4:45 AMSt. Louis, MO
    $2101One-way
    0 transfers
  • Greyhound
    12:55 PM31h15
    Boston, MA
    8:10 PMSt. Louis, MO
    $2241One-way
    0 transfers
  • Greyhound
    10:15 PM53h00
    Boston, MA
    3:15 AMSt. Louis, MO
    $2541One-way
    0 transfers
  • Greyhound
    1:50 AM35h05
    Boston, MA
    12:55 PMSt. Louis, MO
    $2541One-way
    0 transfers

Travel Information

Compare train, bus, and flight for Boston, MA to St. Louis, MO

Omio recommends booking the train as it is the most popular option from Boston, MA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $120. For those with little time consider booking a flight which can get you there in 5h 22m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.5 - 1.5kg. The ticket price range depends on the travel mode: a bus costs an average of $120, and a train costs an average of $185.

Distance: 1035 miles (1667 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

$223

Average price

Cheapest

$938

Average price

$597

Average price

$304

Average price

(fuel + tolls)

30h 37m

Average total duration

30h 7m

Onboard

+

30m

Additional time*

27h 39m

Average total duration

27h 9m

Onboard

+

30m

Additional time*

8h 22m

Average total duration

Fastest

5h 22m

Onboard

+

3h 0m

Additional time*

17h 43m

Average total duration

(door-to-door)

1.7 - 4.2kg

CO2 emissions

0.5 - 1.5kg

CO2 emissions

Lowest

5.0 - 10.0kg

CO2 emissions

-

CO2 emissions

Greyhound

Most popular bus company

Amtrak

Most popular train company

United

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Boston, MA to St. Louis, MO is a bus with an average price of $223.

This is compared to other travel options from Boston, MA to St. Louis, MO:

A bus is $374 less than a flight for this route with tickets for a flight from Boston, MA to St. Louis, MO costing on average $597.

A bus is $715 less than a train for this route with tickets for a train from Boston, MA to St. Louis, MO costing on average $938.

The fastest way to travel from Boston, MA to St. Louis, MO is by flight with an average journey time of 5h 22m.

Other travel options to St. Louis, MO take longer:

Train takes on average 27h 9m.

Bus takes on average 30h 7m.

It's helpful to compare your options as there are 3 ways to travel between Boston, MA and St. Louis, MO including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Boston, MA to St. Louis, MO among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Boston, MA to St. Louis, MO Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
12:35AM
Arrival Time
05:25AM
Duration
28h50
Departure days
Mon, Wed, Thu, Fri, Sat, Sun
Cheapest price
$135
Operator
Greyhound
Departure Time
01:50AM
Arrival Time
12:55PM
Duration
35h05
Departure days
Wed, Thu, Fri, Sat
Cheapest price
$244
Operator
Greyhound
Departure Time
02:50AM
Arrival Time
01:55PM
Duration
35h05
Departure days
Wed, Sat
Cheapest price
$266
Operator
Greyhound
Departure Time
06:00AM
Arrival Time
07:45AM
Duration
26h45
Departure days
Mon
Cheapest price
$164
Operator
Greyhound
Departure Time
06:15AM
Arrival Time
12:55PM
Duration
30h40
Departure days
Thu, Fri, Sat, Sun
Cheapest price
$123
Operator
Greyhound
Departure Time
06:30AM
Arrival Time
12:55PM
Duration
30h25
Departure days
Sat, Sun
Cheapest price
$114
Operator
Greyhound
Departure Time
07:15AM
Arrival Time
01:55PM
Duration
30h40
Departure days
Thu, Sat
Cheapest price
$234
Operator
Greyhound
Departure Time
08:55AM
Arrival Time
03:10PM
Duration
31h15
Departure days
Mon
Cheapest price
$146
Operator
Greyhound
Departure Time
12:55PM
Arrival Time
08:20PM
Duration
31h25
Departure days
Tue, Wed, Thu, Sat
Cheapest price
$171
Operator
Greyhound
Departure Time
01:30PM
Arrival Time
09:20PM
Duration
31h50
Departure days
Fri
Cheapest price
$331
Operator
Greyhound
Departure Time
01:55PM
Arrival Time
09:20PM
Duration
31h25
Departure days
Tue, Wed, Thu, Fri
Cheapest price
$147
Operator
Greyhound
Departure Time
08:15PM
Arrival Time
11:15PM
Duration
28h00
Departure days
Mon
Cheapest price
$210
Operator
Greyhound
Departure Time
09:50PM
Arrival Time
07:45AM
Duration
34h55
Departure days
Mon
Cheapest price
$208
Operator
Greyhound
Departure Time
10:15PM
Arrival Time
03:15AM
Duration
53h00
Departure days
Tue, Thu
Cheapest price
$184
Operator
Greyhound
Departure Time
11:15PM
Arrival Time
04:15AM
Duration
53h00
Departure days
Sun
Cheapest price
$151
Operator
Greyhound
Departure Time
11:35PM
Arrival Time
04:45AM
Duration
29h10
Departure days
Tue, Wed, Fri, Sun
Cheapest price
$162

Live departures

Boston, MA to St. Louis, MO bus times

The table below shows live departures for Boston, MA to St. Louis, MO buses for today, Monday, August 24. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus+Greyhound8:15 PM Boston, Bus Terminal South Station
28h00
11:15 PM St. Louis, S 15th St (Civic center)1 transfer
Tuesday, August 25
Greyhound12:35 AM Boston, MA
28h50
5:25 AM St. Louis, MO0 transfersDirect
Monday, August 24
FlixBusFlixBus+Greyhound · 9:50 PM Boston, Bus Terminal South Station
34h55
7:45 AM St. Louis, S 15th St (Civic center)2 transfers
Tuesday, August 25
Greyhound1:50 AM Boston, MA
35h05
12:55 PM St. Louis, MO0 transfersDirect
Greyhound2:50 AM Boston, MA
35h05
1:55 PM St. Louis, MO0 transfersDirect
Greyhound12:55 PM Boston, MA
31h15
8:10 PM St. Louis, MO0 transfersDirect
Greyhound1:55 PM Boston, MA
31h25
9:20 PM St. Louis, MO0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Boston, MA to St. Louis, MO by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Aug 25
Wed
Aug 26
Thu
Aug 27
Fri
Aug 28
Sat
Aug 29
Sun
Aug 30
Mon
Aug 31

Why should you book Boston, MA to St. Louis, MO buses with Omio?

Greyhound as well as FlixBus offer buses services from Boston, MA to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Boston, MA to St. Louis, MO.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Boston, MA to St. Louis, MO.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Boston, MA to St. Louis, MO.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Boston, MA to St. Louis, MO.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Boston, MA to St. Louis, MO.

Journey information

Overview: Bus from Boston, MA to St. Louis, MO

USAUSA
USAUSA
Icon of bus

Buses from Boston, MA to St. Louis, MO run on average 5 times per day, taking around 30h 7m. Cheap bus tickets for this journey start at $120 if you book in advance.

The earliest bus runs at 01:30, the last at 23:30. The fastest bus covers the 1035 miles (1667 km) distance in 25h 30m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1035 miles (1667 km)
Average bus duration
30h 7m
Cheapest ticket price
$120
Buses per day
5
Fastest bus
25h 30m
First bus
1:30 AM
Last bus
11:30 PM
Cheapest Month
Apr
Cheapest Day
Mon
High Season
Oct - Dec
Low Season
Jul - Sep
Busiest Day
Tue
Least Busy Day
Tue
Best time to book
4 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Boston, MA to St. Louis, MOYou can travel by bus between Boston, MA to St. Louis, MO with Greyhound for as low as $120. When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
25h 30m
Cheapest Price
$120
Greyhound frequency
5 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to St. Louis, MO

Things to do in St. Louis, MO

Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.

  • Must visit

Saint Louis Art Museum

Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.

  • Recommended

Missouri History Museum

Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.

  • Recommended

Saint Louis Science Center

Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.

United States dollar ($)

Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.

Average meal costs

Budget
$10-15 for fast food or casual lunch.
Mid-range
$20-35 per person for a mid-range restaurant meal.
Fine dining
$60+ per person at upscale restaurants.
Coffee
$3-5 for coffee or cappuccino.

Tipping culture

Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.

FAQs: Bus from Boston, MA to St. Louis, MO

Find answers to the most common questions about traveling from Boston, MA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Boston, MA to St. Louis, MO can start from as little as $120 when you book in advance. The average bus ticket price for Boston, MA to St. Louis, MO is $223 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Boston, MA to St. Louis, MO is 25h 30m to travel the 1035 miles (1667 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Boston, MA to St. Louis, MO leaves at 1:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Boston, MA to St. Louis, MO leaves at 11:30 PM.
There are 5 buses a day from Boston, MA to St. Louis, MO which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Boston, MA to St. Louis, MO, you can count on Greyhound, FlixBus for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Boston, MA and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
When departing from Boston, MA , you have various bus station options to start your journey from including Boston, Bus Terminal South Station, Brookline, Harvard St (Coolidge Corner Opticians), MA, Cambridge, Steel Place, MA . When arriving in St. Louis, MO , you can end your journey in bus stations like St. Louis, S 15th St (Civic center), St. Louis, Lambert International Airport .Passengers board the bus most frequently from Boston, Bus Terminal South Station, which is located around away from the city centre, and they get off the bus at St. Louis, S 15th St (Civic center), located 0 away from the city centre.
A trip to St. Louis, MO from Boston, MA is worth doing but not as a day trip with a journey time of 25h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Boston, MA to St. Louis, MO is April.
It's helpful to compare your options as there are 3 ways to travel between Boston, MA and St. Louis, MO including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Boston, MA to St. Louis, MO:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Boston, MA to St. Louis, MO for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Boston, MA to St. Louis, MO depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Boston, MA to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Boston, MA to St. Louis, MO:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Boston, MA to St. Louis, MO:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Boston, MA to St. Louis, MO. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Boston, MA to St. Louis, MO with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Boston, MA to St. Louis, MO with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Boston, MA to St. Louis, MO with the following bus company: Greyhound, FlixBus.
Since neither Boston, MA nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Boston, MA to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Boston, MA to St. Louis, MO

Most Boston, MA to St. Louis, MO buses use the Boston, Bus Terminal South Station to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis, Lambert International Airport. Use this guide to compare Boston, MA and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Boston
Arrival bus stations in St. Louis

Which Boston, MA station do buses to St. Louis, MO leave from?

Buses from Boston, MA to St. Louis, MO leave from Boston, Bus Terminal South Station. The station is 0 miles (1 km) from Boston, MA city centre at Boston-South Station, 700 Atlantic Ave, Boston, MA 02111, USA.
Boston, Bus Terminal South StationBoston-South Station, 700 Atlantic Ave, Boston, MA 02111, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Boston, Bus Terminal South Station from Boston city centre

SubwayRed Line · 2m · $4 · every ~26 min
Red Line · 4m · $4 · every ~26 min

Boston, Bus Terminal South Station bus station facilities and services

Boston, Bus Terminal South Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several fast food and cafe options available.

Wi-Fi and ATMs

Free Wi-Fi available throughout the terminal. ATMs are aTMs located inside the terminal.

Tickets and information

Ticket office support is available at Boston, Bus Terminal South Station.

Parking, taxis and toilets

Available at Boston, Bus Terminal South Station: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Boston, Bus Terminal South Station: Fully accessible with ramps and elevators.

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