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The cheapest and fastest buses from Boston, MA to St. Louis, MO
Showing times and prices for Feb 26
Cheapest price
$266
Average price
$269
Fastest journey
1 d 4 h 50 m
Average duration
1 d 11 h 48 m
Buses per day
5
Distance
1667 km
Cheap tickets
The best way to find a cheap bus ticket from Boston, MA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Boston, MA to St. Louis, MO will cost around $269 if you buy it on the day, but the cheapest tickets can be found for only $266.
Fast buses
It's difficult to get from Boston, MA to St. Louis, MO without transferring at least once.
undefined · undefined07:35PM28h50
Boston, Bus Terminal South Station11:25PMSt. Louis, S 15th St (Civic center)
$2661One-way
1 transfer
undefined · undefined02:15AM30h40
Boston, Bus Terminal South Station07:55AMSt. Louis, S 15th St (Civic center)
$2661One-way
1 transfer
FlixBus · FlixBus · FlixBus+09:50PM35h05
Boston, Bus Terminal South Station07:55AMSt. Louis, S 15th St (Civic center)
$2671One-way
3 transfers
undefined · undefined · undefined08:55AM31h25
Boston, Bus Terminal South Station03:20PMSt. Louis, S 15th St (Civic center)
$2671One-way
2 transfers
FlixBus · FlixBus+undefined · undefined06:15PM53h00
Boston, Bus Terminal South Station10:15PMSt. Louis, Lambert International Airport
$2771One-way
5 transfers
undefined · undefined07:35PM28h50
Boston, Bus Terminal South Station11:25PMSt. Louis, S 15th St (Civic center)
$2661One-way
1 transfer
undefined · undefined02:15AM30h40
Boston, Bus Terminal South Station07:55AMSt. Louis, S 15th St (Civic center)
$2661One-way
1 transfer
undefined · undefined · undefined08:55AM31h25
Boston, Bus Terminal South Station03:20PMSt. Louis, S 15th St (Civic center)
$2671One-way
2 transfers
FlixBus · FlixBus · FlixBus+09:50PM35h05
Boston, Bus Terminal South Station07:55AMSt. Louis, S 15th St (Civic center)
$2671One-way
3 transfers
FlixBus · FlixBus+undefined · undefined06:15PM53h00
Boston, Bus Terminal South Station10:15PMSt. Louis, Lambert International Airport
$2771One-way
5 transfers
Travel Information
Compare train, bus, and flight for Boston, MA to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Boston, MA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $103. For those with little time consider booking a flight which can get you there in 3h 54m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.5 - 1.5kg. The ticket price range depends on the travel mode: a bus costs an average of $103, and a train costs an average of $123.
Distance: 1035 miles (1667 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$214 Average price Cheapest | $406 Average price | $385 Average price |
27h 58m Average total duration 27h 28m Onboard + 30m Additional time* | 27h 50m Average total duration 27h 20m Onboard + 30m Additional time* | 6h 54m Average total duration Fastest 3h 54m Onboard + 3h 0m Additional time* |
1.7 - 4.2kg CO2 emissions | 0.5 - 1.5kg CO2 emissions Lowest | 5.0 - 10.0kg CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Boston, MA to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:15AM | Arrival Time 07:55AM | Duration 30h40 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $151 |
Operator Greyhound | Departure Time 06:00AM | Arrival Time 07:55AM | Duration 26h55 | Departure days Mon | Cheapest price $170 |
Operator Greyhound | Departure Time 08:55AM | Arrival Time 03:20PM | Duration 31h25 | Departure days Mon, Tue, Thu, Fri, Sat | Cheapest price $148 |
Operator Greyhound | Departure Time 09:15AM | Arrival Time 03:20PM | Duration 31h05 | Departure days Sun | Cheapest price $174 |
Operator Greyhound | Departure Time 05:30PM | Arrival Time 10:15PM | Duration 53h45 | Departure days Sat | Cheapest price $237 |
Operator Greyhound | Departure Time 06:15PM | Arrival Time 10:15PM | Duration 53h00 | Departure days Tue, Thu, Fri, Sun | Cheapest price $151 |
Operator Greyhound | Departure Time 07:35PM | Arrival Time 11:25PM | Duration 28h50 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $151 |
Operator Greyhound | Departure Time 09:50PM | Arrival Time 07:55AM | Duration 35h05 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $152 |
Live departures
Boston, MA to St. Louis, MO bus times
The table below shows live departures for Boston, MA to St. Louis, MO buses for today, Wednesday, February 25. You can also manually refresh the results below to see updated bus journeys.
Last updated at 2:04 AM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 2:50 AM Boston, MA | 33h35 | 12:25 PM St. Louis, MO | 0 transfersDirect | |
| 7:15 AM Boston, MA | 30h40 | 1:55 PM St. Louis, MO | 0 transfersDirect | |
| 10:30 PM Boston, MA | 53h45 | 4:15 AM St. Louis, MO | 0 transfersDirect | |
| Thursday, February 26 | |||||
| 12:35 AM Boston, MA | 28h50 | 5:25 AM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Boston, MA to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Boston, MA to St. Louis, MO buses with Omio?
Greyhound as well as FlixBus offer buses services from Boston, MA to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Boston, MA to St. Louis, MO.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Boston, MA to St. Louis, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Boston, MA to St. Louis, MO.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Boston, MA to St. Louis, MO.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Boston, MA to St. Louis, MO.
Journey information
Overview: Bus from Boston, MA to St. Louis, MO
USAUSA
Buses from Boston, MA to St. Louis, MO run on average 4 times per day, taking around 27h 28m. Cheap bus tickets for this journey start at $103 (€82) if you book in advance.
The earliest bus runs at 01:30, the last at 23:30. The fastest bus covers the 1035 miles (1667 km) distance in 26h 55m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1035 miles (1667 km) |
Average bus duration 27h 28m |
Cheapest ticket price $103 (€82) |
Buses per day 4 |
Fastest bus 26h 55m |
First bus 01:30 |
Last bus 23:30 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, FlixBus from Boston, MA to St. Louis, MOYou can travel by bus between Boston, MA to St. Louis, MO with Greyhound, FlixBus for as low as $103 (€82). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
28h 10m
Cheapest Price
$301 (€240)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
26h 55m
Cheapest Price
$103 (€82)
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
FAQs: Bus from Boston, MA to St. Louis, MO
Find answers to the most common questions about traveling from Boston, MA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Boston, MA to St. Louis, MO can start from as little as $103 (€82) when you book in advance. The average bus ticket price for Boston, MA to St. Louis, MO is $217 (€173) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Boston, MA to St. Louis, MO is 26h 55m to travel the 1035 miles (1667 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Boston, MA to St. Louis, MO leaves at 1:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Boston, MA to St. Louis, MO leaves at 11:30 PM.
There are 4 buses a day from Boston, MA to St. Louis, MO which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Boston, MA to St. Louis, MO, you can count on Greyhound, FlixBus for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Boston, MA and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
A trip to St. Louis, MO from Boston, MA is worth doing but not as a day trip with a journey time of 26h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Boston, MA to St. Louis, MO is October.
It's helpful to compare your options as there are 3 ways to travel between Boston, MA and St. Louis, MO including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Boston, MA to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Boston, MA to St. Louis, MO for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Boston, MA to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Boston, MA to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Boston, MA to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Boston, MA to St. Louis, MO:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Boston, MA to St. Louis, MO. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Boston, MA to St. Louis, MO with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Boston, MA to St. Louis, MO with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Boston, MA to St. Louis, MO with the following bus company: Greyhound, FlixBus.
popular bus stations
Popular bus stations from Boston, MA to St. Louis, MO
Boston
St. Louis
The major bus station for departures in Boston is Boston, Bus Terminal South Station. Find all the information you need to know about services, amenities and connections at Boston, Bus Terminal South Station for your trip from Boston to St. Louis.
Boston, Bus Terminal South Station
information
The major bus station for arrivals in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip to St. Louis from Boston.
St. Louis, S 15th St (Civic center)
information
St. Louis, Lambert International Airport
information
More options for your journey from Boston, MA to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Boston, MA
Most popular bus connections to St. Louis, MO
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