- Must visit
Saint Louis Art Museum
Major fine arts museum in Forest Park with collections spanning ancient to contemporary art. A top cultural stop known for its strong permanent collection and landmark building.
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The cheapest and fastest buses from Detroit, MI to St. Louis, MO
Showing times and prices for Jun 26
Cheapest price
$126
Average price
$161
Fastest journey
13 h
Average duration
15 h 21 m
Buses per day
4
Distance
731 km
Cheap tickets
The best way to find a cheap bus ticket from Detroit, MI to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Detroit, MI to St. Louis, MO will cost around $161 if you buy it on the day, but the cheapest tickets can be found for only $126.
Fast buses
It's difficult to get from Detroit, MI to St. Louis, MO without transferring at least once.
+
FlixBus11:15 PM17h25Detroit, Greyhound Terminal3:40 PMSt. Louis, S 15th St (Civic center)$1261One-way1 transfer- +FlixBus4:20 PM15h05Detroit, Greyhound Terminal6:25 AMSt. Louis, S 15th St (Civic center)$1451One-way1 transfer
- · 7:55 PM13h00Detroit, Greyhound Terminal7:55 AMSt. Louis, S 15th St (Civic center)$1721One-way1 transfer
- · · 8:20 AM15h55Detroit, Greyhound Terminal11:15 PMSt. Louis, S 15th St (Civic center)$2031One-way2 transfers
- · 7:55 PM13h00Detroit, Greyhound Terminal7:55 AMSt. Louis, S 15th St (Civic center)$1721One-way1 transfer
- +FlixBus4:20 PM15h05Detroit, Greyhound Terminal6:25 AMSt. Louis, S 15th St (Civic center)$1451One-way1 transfer
- · · 8:20 AM15h55Detroit, Greyhound Terminal11:15 PMSt. Louis, S 15th St (Civic center)$2031One-way2 transfers
- +FlixBus11:15 PM17h25Detroit, Greyhound Terminal3:40 PMSt. Louis, S 15th St (Civic center)$1261One-way1 transfer
Travel Information
Compare train, bus, and flight for Detroit, MI to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Detroit, MI to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $70. For those with little time consider booking a flight which can get you there in 4h 52m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.7kg. The ticket price range depends on the travel mode: a bus costs an average of $70, and a flight costs an average of $123.
Distance: 454 miles (731 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$139 Average price Cheapest | $141 Average price | $368 Average price | $104 Average price (fuel + tolls) |
13h 46m Average total duration 13h 16m Onboard + 30m Additional time* | 11h 4m Average total duration 10h 34m Onboard + 30m Additional time* | 7h 52m Average total duration Fastest 4h 52m Onboard + 3h 0m Additional time* | 7h 46m Average total duration (door-to-door) |
0.7 - 1.8kg CO2 emissions | 0.2 - 0.7kg CO2 emissions Lowest | 2.2 - 4.4kg CO2 emissions | - CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Detroit, MI to St. Louis, MO is a bus with an average price of $139 (€115).
This is compared to other travel options from Detroit, MI to St. Louis, MO:
A bus is $2 (€1) less than a train for this route with tickets for a train from Detroit, MI to St. Louis, MO costing on average $141 (€116).
A bus is $230 (€190) less than a flight for this route with tickets for a flight from Detroit, MI to St. Louis, MO costing on average $368 (€305).
The fastest way to travel from Detroit, MI to St. Louis, MO is by flight with an average journey time of 4h 52m.
Other travel options to St. Louis, MO take longer:
Train takes on average 10h 34m.
Bus takes on average 13h 16m.
It's helpful to compare your options as there are 3 ways to travel between Detroit, MI and St. Louis, MO including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Detroit, MI to St. Louis, MO among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Detroit, MI to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:15AM | Arrival Time 11:15PM | Duration 17h00 | Departure days Wed, Thu | Cheapest price $89 |
Operator Greyhound | Departure Time 08:20AM | Arrival Time 11:15PM | Duration 15h55 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $101 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 06:25AM | Duration 15h05 | Departure days Everyday | Cheapest price $89 |
Operator Greyhound | Departure Time 07:55PM | Arrival Time 07:55AM | Duration 13h00 | Departure days Everyday | Cheapest price $91 |
Operator Greyhound | Departure Time 11:15PM | Arrival Time 03:40PM | Duration 17h25 | Departure days Everyday | Cheapest price $91 |
Live departures
Detroit, MI to St. Louis, MO bus times
The table below shows live departures for Detroit, MI to St. Louis, MO buses for today, Thursday, June 25. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · | 7:15 AM Detroit, Greyhound Terminal | 17h00 | 11:15 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
| +FlixBus | 4:20 PM Detroit, Greyhound Terminal | 15h05 | 6:25 AM St. Louis, S 15th St (Civic center) | 1 transfer | |
| · | 7:55 PM Detroit, Greyhound Terminal | 13h00 | 7:55 AM St. Louis, S 15th St (Civic center) | 1 transfer | |
| +FlixBus | 11:15 PM Detroit, Greyhound Terminal | 17h25 | 3:40 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Detroit, MI to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Detroit, MI to St. Louis, MO buses with Omio?
Greyhound as well as FlixBus or Barons Bus offer buses services from Detroit, MI to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Detroit, MI to St. Louis, MO.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus or Barons Bus to find the best option for your trip from Detroit, MI to St. Louis, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Detroit, MI to St. Louis, MO.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus or Barons Bus to find the best option for your trip from Detroit, MI to St. Louis, MO.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Detroit, MI to St. Louis, MO.
Journey information
Overview: Bus from Detroit, MI to St. Louis, MO
USAUSA
Buses from Detroit, MI to St. Louis, MO run on average 3 times per day, taking around 13h 16m. Cheap bus tickets for this journey start at $70 (€57) if you book in advance.
The earliest bus runs at 02:00, the last at 23:55. The fastest bus covers the 454 miles (731 km) distance in 12h 40m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 454 miles (731 km) |
Average bus duration 13h 16m |
Cheapest ticket price $70 (€57) |
Buses per day 3 |
Fastest bus 12h 40m |
First bus 2:00 AM |
Last bus 11:55 PM |
Cheapest Month Dec |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 21 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, FlixBus, Barons Bus from Detroit, MI to St. Louis, MOYou can travel by bus between Detroit, MI to St. Louis, MO with Greyhound, FlixBus, Barons Bus for as low as $70 (€57). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
15h 5m
Cheapest Price
$94 (€78)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
12h 40m
Cheapest Price
$70 (€57)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Barons Bus
Luggage & cancellation policy
Average Duration
14h 50m
Cheapest Price
$138 (€114)
Barons Bus frequency
1 a day
Complete guide to St. Louis
Things to do in St. Louis
Discover the best of St. Louis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis trip today.
- Must visit
City Museum
A highly original artist-built museum and playground inside a former warehouse, blending sculpture, tunnels, slides, and architectural salvage. One of the city’s most distinctive attractions.
- Recommended
Missouri History Museum
History museum in Forest Park covering St. Louis, Missouri, and regional stories through permanent and rotating exhibitions. Useful for understanding the city’s cultural context.
- Must visit
Forest Park
One of the largest urban parks in the United States, home to major cultural institutions, lakes, trails, and iconic landscapes. A must for first-time visitors.
- Must visit
Gateway Arch National Park Grounds
Landscaped riverfront grounds around the Arch, ideal for walking, photography, and skyline views. A central outdoor area tied to the city’s identity.
- Recommended
Delmar Loop
Lively entertainment and street-life district known for music venues, public art, shops, and the St. Louis Walk of Fame. Popular with both locals and younger visitors.
Toasted Ravioli
Breaded and deep-fried ravioli, usually filled with meat or cheese, served with marinara. It is one of St. Louis's signature Italian-American snacks from The Hill.
- Vegetarian
St. Louis-Style Pizza
A thin, cracker-like pizza cut into squares and typically topped with Provel cheese. It is a defining local style strongly associated with St. Louis.
- Vegetarian
Gooey Butter Cake
A rich, sweet cake with a dense buttery base and soft cream-cheese-like topping. It is a classic St. Louis dessert found in bakeries across the city.
Charlie Gitto's On The Hill
Long-running Italian restaurant in The Hill neighborhood, known for toasted ravioli, pasta, and classic red-sauce dishes in a polished traditional setting.
Ted Drewes Frozen Custard
Historic frozen custard stand famous for thick concretes and classic custard treats. Casual, iconic, and essential for a true St. Louis dessert experience.
Sidney Street Cafe
Established fine-dining restaurant serving refined New American cuisine in a stylish yet approachable atmosphere, well regarded for special occasions.
United States Dollar
Generally moderate for U.S. city travel. Hotels vary by season, while casual dining and transport are fairly affordable.
Average meal costs
- Budget
- USD 10-15 for fast food or casual lunch.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 60+ per person at upscale restaurants.
- Coffee
- USD 3-6 for a coffee drink.
Tipping culture
Tip 18-20% at restaurants; 20%+ for great service. Tip USD 1-2 per drink at bars, round up or 10-15% for taxis, and USD 2-5 for hotel staff as appropriate.
FAQs: Bus from Detroit, MI to St. Louis, MO
Find answers to the most common questions about traveling from Detroit, MI to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Detroit, MI to St. Louis, MO can start from as little as $70 (€57) when you book in advance. The average bus ticket price for Detroit, MI to St. Louis, MO is $139 (€115) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Detroit, MI to St. Louis, MO is 12h 40m to travel the 454 miles (731 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Detroit, MI to St. Louis, MO leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Detroit, MI to St. Louis, MO leaves at 11:55 PM.
There are 3 buses a day from Detroit, MI to St. Louis, MO which require at least one change with Greyhound, FlixBus, Barons Bus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Detroit, MI to St. Louis, MO, you can count on Greyhound, FlixBus, Barons Bus for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Detroit, MI and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
A trip to St. Louis, MO from Detroit, MI is worth doing but not as a day trip with a journey time of 12h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Detroit, MI to St. Louis, MO is December.
It's helpful to compare your options as there are 3 ways to travel between Detroit, MI and St. Louis, MO including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Detroit, MI to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Detroit, MI to St. Louis, MO for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Detroit, MI to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Detroit, MI to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Detroit, MI to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Detroit, MI to St. Louis, MO:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Detroit, MI to St. Louis, MO. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Detroit, MI to St. Louis, MO with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Detroit, MI to St. Louis, MO with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Detroit, MI to St. Louis, MO with the following bus company: Greyhound, FlixBus.
Since neither Detroit, MI nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Detroit, MI to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Detroit, MI to St. Louis, MO
Most Detroit, MI to St. Louis, MO buses use the Detroit, Greyhound Terminal to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Detroit, MI and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Detroit
Arrival bus stations in St. Louis
Detroit, Greyhound Terminal
St. Louis, S 15th St (Civic center)
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
Most popular bus connections from Detroit, MI
More options for your journey from Detroit, MI to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Detroit, MI
Most popular bus connections to St. Louis, MO
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