- Must visit
Saint Louis Art Museum
Major fine arts museum in Forest Park with collections spanning ancient to modern works. A top cultural stop known for strong European, American, and global holdings.
Cheapest price
$148
Average price
$168
Fastest journey
20 h 25 m
Average duration
21 h 14 m
Buses per day
14
Distance
1094 km
The best way to find a cheap bus ticket from Houston, TX to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Houston, TX to St. Louis, MO will cost around $168 if you buy it on the day, but the cheapest tickets can be found for only $148.
It's difficult to get from Houston, TX to St. Louis, MO without transferring at least once.
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Omio recommends booking the train as it is the most popular option from Houston, TX to St. Louis, MO among Omio's users. If you are prioritising price take the train with prices starting from $125. For those with little time consider booking a flight which can get you there in 2h 4m. The ticket price range depends on the travel mode: a train costs an average of $125, and a flight costs an average of $217.
Distance: 679 miles (1094 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$240 Average price | $169 Average price Cheapest | $457 Average price | $158 Average price (fuel + tolls) |
20h 12m Average total duration 19h 42m Onboard + 30m Additional time* | 18h 36m Average total duration 18h 6m Onboard + 30m Additional time* | 5h 4m Average total duration Fastest 2h 4m Onboard + 3h 0m Additional time* | 11h 59m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Houston, TX to St. Louis, MO:
A train is $71 (€58) less than a bus for this route with tickets for a bus from Houston, TX to St. Louis, MO costing on average $240 (€196).
A train is $289 (€236) less than a flight for this route with tickets for a flight from Houston, TX to St. Louis, MO costing on average $457 (€374).
Other travel options to St. Louis, MO take longer:
Train takes on average 18h 6m.
Bus takes on average 19h 42m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:50AM | Arrival Time 10:45PM | Duration 20h55 | Departure days Everyday | Cheapest price $123 |
Operator Greyhound | Departure Time 06:35AM | Arrival Time 12:55PM | Duration 30h20 | Departure days Everyday | Cheapest price $120 |
Operator Greyhound | Departure Time 08:15AM | Arrival Time 07:10AM | Duration 22h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $123 |
Operator FlixBus | Departure Time 10:00AM | Arrival Time 07:10AM | Duration 21h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $123 |
Operator Greyhound | Departure Time 10:25AM | Arrival Time 07:10AM | Duration 20h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $123 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 12:55PM | Duration 25h45 | Departure days Wed, Thu | Cheapest price $122 |
Operator Greyhound | Departure Time 01:15PM | Arrival Time 12:55PM | Duration 23h40 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $157 |
Operator Greyhound | Departure Time 01:40PM | Arrival Time 12:55PM | Duration 23h15 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $159 |
Operator Greyhound | Departure Time 01:45PM | Arrival Time 12:55PM | Duration 23h10 | Departure days Everyday | Cheapest price $141 |
Operator Greyhound | Departure Time 05:15PM | Arrival Time 10:15PM | Duration 29h00 | Departure days Wed, Thu | Cheapest price $131 |
Operator Greyhound | Departure Time 06:55PM | Arrival Time 10:45PM | Duration 27h50 | Departure days Everyday | Cheapest price $136 |
Operator Greyhound | Departure Time 07:35PM | Arrival Time 10:15PM | Duration 26h40 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $137 |
Operator Greyhound | Departure Time 10:00PM | Arrival Time 11:00PM | Duration 25h00 | Departure days Fri | Cheapest price $151 |
The table below shows live departures for Houston, TX to St. Louis, MO buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus+![]() | 8:15 AM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 22h55 | 7:10 AM St. Louis, S 15th St (Civic center) | 2 transfers | |
FlixBus+![]() | 10:00 AM Houston, Gray St Parking (Bus Station), TX | 21h10 | 7:10 AM St. Louis, S 15th St (Civic center) | 1 transfer | |
FlixBus+![]() | 10:25 AM Houston, TX | 20h45 | 7:10 AM St. Louis, S 15th St (Civic center) | 1 transfer | |
FlixBus+ · | 1:15 PM Houston, Gray St Parking (Bus Station), TX | 23h40 | 12:55 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
FlixBus+ · | 1:40 PM Houston, TX | 23h15 | 12:55 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
· · | 1:45 PM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 23h10 | 12:55 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
· · | 6:55 PM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 27h50 | 10:45 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
· · | 6:55 PM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 27h20 | 10:15 PM St. Louis, Lambert International Airport | 2 transfers | |
FlixBus+ · · | 7:35 PM Houston, Gray St Parking (Bus Station), TX | 26h40 | 10:15 PM St. Louis, Lambert International Airport | 3 transfers | |
FlixBus+ · · | 7:35 PM Houston, Gray St Parking (Bus Station), TX | 27h10 | 10:45 PM St. Louis, S 15th St (Civic center) | 3 transfers | |
· · | 1:50 AM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 20h55 | 10:45 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
· · | 1:50 AM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 20h25 | 10:15 PM St. Louis, Lambert International Airport | 2 transfers | |
· · +![]() | 6:35 AM Houston, Southwest Fwy (Chevron), TX | 30h20 | 12:55 PM St. Louis, S 15th St (Civic center) | 3 transfers | |
· · +![]() | 6:35 AM Houston, Southwest Fwy (Chevron), TX | 39h40 | 10:15 PM St. Louis, Lambert International Airport | 4 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Houston, TX to St. Louis, MO run on average 14 times per day, taking around 19h 42m. Cheap bus tickets for this journey start at $119 (€97) if you book in advance.
The earliest bus runs at 00:05, the last at 23:45. The fastest bus covers the 679 miles (1094 km) distance in 20h 55m.
Distance 679 miles (1094 km) |
Average bus duration 19h 42m |
Cheapest ticket price $119 (€97) |
Buses per day 14 |
Fastest bus 20h 55m |
First bus 12:05 AM |
Last bus 11:45 PM |
Cheapest Month Oct |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jul - Sep |
Best time to book 28 days |
Discover the best of St. Louis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis trip today.
Major fine arts museum in Forest Park with collections spanning ancient to modern works. A top cultural stop known for strong European, American, and global holdings.
Highly original museum and artist-built environment with architectural salvage, tunnels, slides, and installations. One of the city’s most distinctive and widely shared attractions.
History museum in Forest Park covering St. Louis, Missouri, and regional stories through permanent and rotating exhibitions. Well suited for visitors wanting local context.
One of the largest urban parks in the United States, home to major institutions, lakes, trails, and broad green spaces. Essential for first-time visitors.
Riverfront grounds around the Arch with lawns, paths, and strong skyline views, useful for walking and iconic photos.
Lively entertainment and walking district known for music venues, public art, shops, and the St. Louis Walk of Fame.
A local pizza style with a very thin, cracker-like crust, cut into squares and traditionally topped with Provel cheese. It is one of the city’s signature foods.
Breaded and fried meat- or cheese-filled ravioli, usually served with marinara sauce. This St. Louis Italian-American specialty is strongly associated with The Hill neighborhood.
A rich, dense cake with a buttery base and sweet cream cheese-like topping. It is one of the most famous desserts identified with St. Louis.
A long-established Italian restaurant on The Hill, known for classic red-sauce dishes, toasted ravioli, and an old-school fine dining feel.
An iconic St. Louis custard stand famous for thick concretes and nostalgic roadside charm. A must for trying the city’s best-known frozen treat.
A respected contemporary American restaurant known for refined cooking, strong wine service, and a polished neighborhood setting.
Generally moderate by U.S. standards. Hotels and attractions are often reasonable, while dining costs vary by neighborhood and venue.
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Houston, TX to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Houston, TX to St. Louis, MO buses use the Houston, Harrisburg Blvd (Greyhound Bus Station) to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis, Lambert International Airport. Use this guide to compare Houston, TX and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need