The cheapest and fastest buses from Los Angeles, CA to St. Louis, MO
Cheapest price
$170
Average price
$306
Fastest journey
1 d 16 h 15 m
Average duration
1 d 21 h 4 m
Buses per day
4
Distance
2553 km
The best way to find a cheap bus ticket from Los Angeles, CA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Los Angeles, CA to St. Louis, MO will cost around $306 if you buy it on the day, but the cheapest tickets can be found for only $170.
Of the 4 buses that leave Los Angeles, CA for St. Louis, MO on Wed, Dec 10, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Dec 10 the direct buses cover the 2553 km distance in an average of 1 d 21 h 4 m but if you time it right, some buses will get you there in just 1 d 16 h 15 m .
On Wed, Dec 10 the slowest buses will take 2 d 7 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Compare bus, train, and flight for Los Angeles, CA to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Los Angeles, CA to St. Louis, MO among Omio's users. If you are prioritising price take the flight with prices starting from €140. For those with little time consider booking a flight which can get you there in 4h 10m. The ticket price range depends on the travel mode: a flight costs an average of €140, and a train costs an average of €403.
Distance: 1586 miles (2553 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€160 Average price | €431 Average price | €140 Average price Cheapest |
40h 56m Average total duration 40h 26m Onboard + 30m Additional time* | 44h 29m Average total duration 43h 59m Onboard + 30m Additional time* | 7h 10m Average total duration Fastest 4h 10m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Los Angeles, CA to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 09:35AM | Arrival Time 07:10AM | Duration 43h35 | Departure days Wed, Thu, Sat | Cheapest price $280 |
Operator Greyhound | Departure Time 12:55PM | Arrival Time 07:10AM | Duration 40h15 | Departure days Wed, Thu, Sat | Cheapest price $170 |
Operator Greyhound | Departure Time 01:20PM | Arrival Time 10:50PM | Duration 55h30 | Departure days Wed, Thu, Sat | Cheapest price $245 |
Operator Greyhound | Departure Time 06:00PM | Arrival Time 12:55PM | Duration 40h55 | Departure days Wed, Thu, Sat | Cheapest price $240 |
Live departures
Los Angeles, CA to St. Louis, MO bus times
The table below shows live departures for Los Angeles, CA to St. Louis, MO buses for today, Tuesday, December 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:55 PM Los Angeles, CA | 40h10 | 12:05 PM St. Louis, MO | 0 transfersDirect | |
| Wednesday, December 10 | |||||
![]() | 12:30 AM Los Angeles, CA | 46h10 | 10:40 PM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Los Angeles, CA to St. Louis, MO by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 10
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Dec 16
Journey information
Overview: Bus from Los Angeles, CA to St. Louis, MO
Buses from Los Angeles, CA to St. Louis, MO run on average 11 times per day, taking around 40h 26m. Cheap bus tickets for this journey start at $141 (€114) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:25, the last at 23:55. The fastest bus covers the 1586 miles (2553 km) distance in 40h 10m.
Distance 1586 miles (2553 km) |
Average bus duration 40h 26m |
Cheapest ticket price $141 (€114) |
Buses per day 11 |
Direct buses 3 |
Fastest bus 40h 10m |
First bus 00:25 |
Last bus 23:55 |
Bus providers: Greyhound, FlixBus from Los Angeles, CA to St. Louis, MOYou can travel by bus between Los Angeles, CA to St. Louis, MO with Greyhound, FlixBus for as low as $141 (€114). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Los Angeles, CA to St. Louis, MO
Find answers to the most common questions about traveling from Los Angeles, CA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Los Angeles, CA to St. Louis, MO, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Los Angeles, CA to St. Louis, MO
Most popular bus connections from Los Angeles, CA
More options for your journey from Los Angeles, CA to St. Louis, MO
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