- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
The best way to find a cheap bus ticket from Los Angeles, CA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Los Angeles, CA to St. Louis, MO will cost around $131 if you buy it on the day, but the cheapest tickets can be found for only $126.
On Tue, Nov 03, we found 12 buses from Los Angeles, CA to St. Louis, MO, including 1 direct services.
On Tue, Nov 03 the direct buses cover the 2553 km distance in an average of 1 d 18 h 47 m but if you time it right, some buses will get you there in just 1 d 16 h 15 m .
On Tue, Nov 03 the slowest buses will take 1 d 20 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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Buses from Los Angeles, CA to St. Louis, MO run on average 10 times per day, taking around 45h 15m. Cheap bus tickets for this journey start at $96 if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:25, the last at 23:55. The fastest bus covers the 1586 miles (2553 km) distance in 37h 40m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Los Angeles, CA to St. Louis, MO.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:30AM | Arrival Time 10:15PM | Duration 43h45 | Departure days Everyday | Cheapest price $124 |
Operator Greyhound | Departure Time 01:20AM | Arrival Time 10:10PM | Duration 66h50 | Departure days Mon | Cheapest price $311 |
Operator Greyhound | Departure Time 01:25AM | Arrival Time 12:55PM | Duration 57h30 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $119 |
Operator Greyhound | Departure Time 01:35AM | Arrival Time 10:10PM | Duration 66h35 | Departure days Mon | Cheapest price $273 |
Operator Greyhound | Departure Time 01:40AM | Arrival Time 10:15PM | Duration 66h35 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $119 |
Operator Greyhound | Departure Time 12:55PM | Arrival Time 07:10AM | Duration 40h15 | Departure days Everyday | Cheapest price $131 |
Operator Greyhound | Departure Time 01:45PM | Arrival Time 10:15PM | Duration 54h30 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $122 |
Operator Greyhound | Departure Time 06:00PM | Arrival Time 12:55PM | Duration 40h55 | Departure days Everyday | Cheapest price $121 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 10:45PM | Duration 45h15 | Departure days Everyday | Cheapest price $122 |
The table below shows live departures for Los Angeles, CA to St. Louis, MO buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 12:30 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 44h15 | 10:45 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
· | 12:30 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 43h40 | 10:10 PM St. Louis, Lambert International Airport | 1 transfer | |
FlixBus+ · · | 1:20 AM Los Angeles, Exposition Blvd / South Sepulveda Blvd, CA | 66h50 | 10:10 PM St. Louis, Lambert International Airport | 4 transfers | |
FlixBus+ · · | 1:20 AM Los Angeles, Exposition Blvd / South Sepulveda Blvd, CA | 57h55 | 1:15 PM St. Louis, S 15th St (Civic center) | 3 transfers | |
FlixBus+ · · | 1:35 AM Los Angeles, Gayley / Strathmore, CA | 57h40 | 1:15 PM St. Louis, S 15th St (Civic center) | 3 transfers | |
FlixBus+ · · | 1:35 AM Los Angeles, Gayley / Strathmore, CA | 66h35 | 10:10 PM St. Louis, Lambert International Airport | 4 transfers | |
![]() | 12:55 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 40h10 | 7:05 AM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
FlixBus+ · · | 1:45 PM Los Angeles, Cesar E Chavez / Vignes, CA | 54h25 | 10:10 PM St. Louis, Lambert International Airport | 4 transfers | |
FlixBus+ · · | 1:45 PM Los Angeles, Cesar E Chavez / Vignes, CA | 55h00 | 10:45 PM St. Louis, S 15th St (Civic center) | 4 transfers | |
· · | 6:00 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 41h15 | 1:15 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
Find all the dates and times for this journey
Buses from Los Angeles, CA to St. Louis, MO with Greyhound. Overnight buses available on this route with Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in St. Louis, MO.
Find answers to the most common questions about traveling from Los Angeles, CA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Los Angeles, CA to St. Louis, MO buses use the Los Angeles, Patsaouras Transit Plaza (Union Station) to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis, Lambert International Airport. Use this guide to compare Los Angeles, CA and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Los Angeles, Patsaouras Transit Plaza (Union Station) is 1 km from Los Angeles city centre. Public transport options include:
Los Angeles, Patsaouras Transit Plaza (Union Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food court and various dining options available.
Wi-Fi available in main waiting areas. ATMs are aTMs available near main concourse.
Ticket office support is available at Los Angeles, Patsaouras Transit Plaza (Union Station).
Available at Los Angeles, Patsaouras Transit Plaza (Union Station): Parking, Taxis, WC.
Accessibility facilities are available at Los Angeles, Patsaouras Transit Plaza (Union Station): Station fully accessible with elevators and ramps.
Los Angeles, Cesar E Chavez / Vignes is 1 km from Los Angeles city centre. Public transport options include:
Los Angeles, Cesar E Chavez / Vignes has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Los Angeles, Cesar E Chavez / Vignes. ATMs are available at Los Angeles, Cesar E Chavez / Vignes.
Ticket office support is available at Los Angeles, Cesar E Chavez / Vignes.
Available at Los Angeles, Cesar E Chavez / Vignes: Parking, Taxis, WC.
Accessibility facilities are available at Los Angeles, Cesar E Chavez / Vignes: The station is accessible to people with disabilities.
Los Angeles, Gayley / Strathmore is 19 km from Los Angeles city centre. Public transport options include:
Los Angeles, Gayley / Strathmore has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Los Angeles, Gayley / Strathmore. ATMs are available at Los Angeles, Gayley / Strathmore.
Ticket office support is available at Los Angeles, Gayley / Strathmore.
Available at Los Angeles, Gayley / Strathmore: Parking, Taxis, WC.
Accessibility facilities are available at Los Angeles, Gayley / Strathmore: Basic accessibility features available for buses.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple dining options available in terminals.
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Ticket office support is available at St. Louis, Lambert International Airport.
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
Check bus stations information for Los Angeles, CA and St. Louis, MO, including where buses depart and arrive on this route.