The cheapest and fastest buses from Los Angeles, CA to St. Louis, MO
Cheapest price
$280
Average price
$289
Fastest journey
1 d 16 h 15 m
Average duration
1 d 16 h 35 m
Buses per day
2
Distance
2553 km
The best way to find a cheap bus ticket from Los Angeles, CA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Los Angeles, CA to St. Louis, MO will cost around $289 if you buy it on the day, but the cheapest tickets can be found for only $280.
Of the 2 buses that leave Los Angeles, CA for St. Louis, MO on Sat, Mar 28, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Mar 28 the direct buses cover the 2553 km distance in an average of 1 d 16 h 35 m but if you time it right, some buses will get you there in just 1 d 16 h 15 m .
On Sat, Mar 28 the slowest buses will take 1 d 16 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Los Angeles, CA to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Los Angeles, CA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $126. For those with little time consider booking a flight which can get you there in 4h 10m. The ticket price range depends on the travel mode: a bus costs an average of $126, and a train costs an average of $179.
Distance: 1586 miles (2553 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$216 Average price Cheapest | $305 Average price | $300 Average price |
41h 15m Average total duration 40h 45m Onboard + 30m Additional time* | 43h 37m Average total duration 43h 7m Onboard + 30m Additional time* | 7h 10m Average total duration Fastest 4h 10m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Los Angeles, CA to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:35AM | Arrival Time 10:45PM | Duration 44h10 | Departure days Sat | Cheapest price $513 |
Operator Greyhound | Departure Time 09:30AM | Arrival Time 10:15PM | Duration 58h45 | Departure days Sat | Cheapest price $437 |
Operator Greyhound | Departure Time 09:35AM | Arrival Time 07:10AM | Duration 43h35 | Departure days Sat | Cheapest price $435 |
Operator Greyhound | Departure Time 12:55PM | Arrival Time 07:10AM | Duration 40h15 | Departure days Sat | Cheapest price $247 |
Operator Greyhound | Departure Time 01:20PM | Arrival Time 10:15PM | Duration 54h55 | Departure days Sat | Cheapest price $420 |
Operator Greyhound | Departure Time 06:00PM | Arrival Time 12:55PM | Duration 40h55 | Departure days Sat | Cheapest price $436 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 10:45PM | Duration 45h15 | Departure days Sat | Cheapest price $461 |
Live departures
Los Angeles, CA to St. Louis, MO bus times
The table below shows live departures for Los Angeles, CA to St. Louis, MO buses for today, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus+![]() | 4:30 PM Los Angles, S Hope St. USC Parking, CA | 58h45 | 3:15 AM St. Louis, Lambert International Airport | 5 transfers | |
FlixBus+![]() | 4:35 PM Los Angeles, Cesar E Chavez / Vignes, CA | 43h35 | 12:10 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
![]() | 7:55 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 40h15 | 12:10 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
FlixBus+ undefined · undefined · undefined | 8:20 PM Los Angeles, Cesar E Chavez / Vignes, CA | 54h55 | 3:15 AM St. Louis, Lambert International Airport | 3 transfers | |
FlixBus+ undefined · undefined · undefined | 8:20 PM Los Angeles, Cesar E Chavez / Vignes, CA | 55h25 | 3:45 AM St. Louis, S 15th St (Civic center) | 3 transfers | |
undefined · undefined · undefined | 1:00 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 40h55 | 5:55 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
![]() | 2:00 AM Los Angeles, CA | 40h55 | 6:55 PM St. Louis, MO | 0 transfersDirect | |
undefined · undefined | 6:30 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 45h15 | 3:45 AM St. Louis, S 15th St (Civic center) | 1 transfer | |
undefined · undefined | 6:30 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 44h45 | 3:15 AM St. Louis, Lambert International Airport | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Los Angeles, CA to St. Louis, MO by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Mar 28
Why should you book Los Angeles, CA to St. Louis, MO buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Los Angeles, CA to St. Louis, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Los Angeles, CA to St. Louis, MO.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Los Angeles, CA to St. Louis, MO.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Los Angeles, CA to St. Louis, MO.
Journey information
Overview: Bus from Los Angeles, CA to St. Louis, MO
Buses from Los Angeles, CA to St. Louis, MO run on average 8 times per day, taking around 40h 45m. Cheap bus tickets for this journey start at $126 (€102) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:25, the last at 23:55. The fastest bus covers the 1586 miles (2553 km) distance in 40h 15m.
Distance 1586 miles (2553 km) |
Average bus duration 40h 45m |
Cheapest ticket price $126 (€102) |
Buses per day 8 |
Direct buses 2 |
Fastest bus 40h 15m |
First bus 00:25 |
Last bus 23:55 |
Cheapest month Feb |
Cheapest day Sun |
High season Oct - Dec |
Low season Apr - Jun |
Busiest day Fri |
Least busy day Fri |
Best day to book ahead 21 days |
Bus providers: Greyhound, FlixBus from Los Angeles, CA to St. Louis, MOYou can travel by bus between Los Angeles, CA to St. Louis, MO with Greyhound, FlixBus for as low as $126 (€102). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Los Angeles, CA to St. Louis, MO
Find answers to the most common questions about traveling from Los Angeles, CA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Los Angeles, CA to St. Louis, MO
Most popular bus connections from Los Angeles, CA
More options for your journey from Los Angeles, CA to St. Louis, MO
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