- Must visit
Saint Louis Art Museum
Major fine arts museum in Forest Park with collections spanning ancient to modern works. A top cultural stop known for strong European, American, and global holdings.
Cheapest price
$289
Average price
$364
Fastest journey
1 d 16 h 15 m
Average duration
1 d 18 h 31 m
Buses per day
9
Distance
2553 km
The best way to find a cheap bus ticket from Los Angeles, CA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Los Angeles, CA to St. Louis, MO will cost around $364 if you buy it on the day, but the cheapest tickets can be found for only $289.
Of the 9 buses that leave Los Angeles, CA for St. Louis, MO on Sat, Jun 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 2553 km distance in an average of 1 d 18 h 31 m but if you time it right, some buses will get you there in just 1 d 16 h 15 m .
On Sat, Jun 20 the slowest buses will take 1 d 20 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus+
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· Omio recommends booking the train as it is the most popular option from Los Angeles, CA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $105. For those with little time consider booking a flight which can get you there in 4h 12m. The ticket price range depends on the travel mode: a bus costs an average of $105, and a train costs an average of $171.
Distance: 1586 miles (2553 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$193 Average price Cheapest | $309 Average price | $291 Average price |
41h 54m Average total duration 41h 24m Onboard + 30m Additional time* | 43h 57m Average total duration 43h 27m Onboard + 30m Additional time* | 7h 12m Average total duration Fastest 4h 12m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Los Angeles, CA to St. Louis, MO:
A bus is $97 (€80) less than a flight for this route with tickets for a flight from Los Angeles, CA to St. Louis, MO costing on average $291 (€238).
A bus is $115 (€95) less than a train for this route with tickets for a train from Los Angeles, CA to St. Louis, MO costing on average $309 (€253).
Other travel options to St. Louis, MO take longer:
Bus takes on average 41h 24m.
Train takes on average 43h 27m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:35AM | Arrival Time 10:45PM | Duration 44h10 | Departure days Thu, Fri, Sat | Cheapest price $190 |
Operator Greyhound | Departure Time 01:00AM | Arrival Time 05:55PM | Duration 40h55 | Departure days Thu | Cheapest price $129 |
Operator Greyhound | Departure Time 06:50AM | Arrival Time 03:15AM | Duration 44h25 | Departure days Mon, Tue | Cheapest price $217 |
Operator Greyhound | Departure Time 09:35AM | Arrival Time 07:10AM | Duration 43h35 | Departure days Thu, Fri, Sat | Cheapest price $187 |
Operator Greyhound | Departure Time 12:55PM | Arrival Time 07:10AM | Duration 40h15 | Departure days Thu, Fri, Sat | Cheapest price $178 |
Operator Greyhound | Departure Time 01:45PM | Arrival Time 10:15PM | Duration 54h30 | Departure days Thu, Fri, Sat | Cheapest price $173 |
Operator Greyhound | Departure Time 06:00PM | Arrival Time 12:55PM | Duration 40h55 | Departure days Thu, Fri, Sat | Cheapest price $157 |
Operator Greyhound | Departure Time 07:55PM | Arrival Time 12:10PM | Duration 40h15 | Departure days Mon, Tue, Wed, Sun | Cheapest price $171 |
Operator Greyhound | Departure Time 08:55PM | Arrival Time 01:10PM | Duration 40h15 | Departure days Mon, Tue, Wed | Cheapest price $177 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 10:15PM | Duration 44h45 | Departure days Thu, Fri, Sat | Cheapest price $172 |
The table below shows live departures for Los Angeles, CA to St. Louis, MO buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 9:35 AM Los Angeles, Cesar E Chavez / Vignes, CA | 43h35 | 7:10 AM St. Louis, S 15th St (Civic center) | 1 transfer | |
![]() | 12:55 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 40h15 | 7:10 AM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
FlixBus+ · · | 1:45 PM Los Angeles, Cesar E Chavez / Vignes, CA | 54h30 | 10:15 PM St. Louis, Lambert International Airport | 3 transfers | |
FlixBus+ · · | 1:45 PM Los Angeles, Cesar E Chavez / Vignes, CA | 55h00 | 10:45 PM St. Louis, S 15th St (Civic center) | 3 transfers | |
· · | 6:00 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 40h55 | 12:55 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
· | 11:30 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 44h45 | 10:15 PM St. Louis, Lambert International Airport | 1 transfer | |
· | 11:30 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 45h15 | 10:45 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
| Saturday, June 20 | |||||
· | 12:35 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 43h40 | 10:15 PM St. Louis, Lambert International Airport | 1 transfer | |
· | 12:35 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 44h10 | 10:45 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Los Angeles, CA to St. Louis, MO run on average 8 times per day, taking around 41h 24m. Cheap bus tickets for this journey start at $105 (€86) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:25, the last at 23:55. The fastest bus covers the 1586 miles (2553 km) distance in 40h 15m.
Distance 1586 miles (2553 km) |
Average bus duration 41h 24m |
Cheapest ticket price $105 (€86) |
Buses per day 8 |
Direct buses 2 |
Fastest bus 40h 15m |
First bus 12:25 AM |
Last bus 11:55 PM |
Cheapest Month Nov |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 21 days |
Discover the best of St. Louis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis trip today.
Major fine arts museum in Forest Park with collections spanning ancient to modern works. A top cultural stop known for strong European, American, and global holdings.
Highly original museum and artist-built environment with architectural salvage, tunnels, slides, and installations. One of the city’s most distinctive and widely shared attractions.
History museum in Forest Park covering St. Louis, Missouri, and regional stories through permanent and rotating exhibitions. Well suited for visitors wanting local context.
One of the largest urban parks in the United States, home to major institutions, lakes, trails, and broad green spaces. Essential for first-time visitors.
Riverfront grounds around the Arch with lawns, paths, and strong skyline views, useful for walking and iconic photos.
Lively entertainment and walking district known for music venues, public art, shops, and the St. Louis Walk of Fame.
A local pizza style with a very thin, cracker-like crust, cut into squares and traditionally topped with Provel cheese. It is one of the city’s signature foods.
Breaded and fried meat- or cheese-filled ravioli, usually served with marinara sauce. This St. Louis Italian-American specialty is strongly associated with The Hill neighborhood.
A rich, dense cake with a buttery base and sweet cream cheese-like topping. It is one of the most famous desserts identified with St. Louis.
A long-established Italian restaurant on The Hill, known for classic red-sauce dishes, toasted ravioli, and an old-school fine dining feel.
An iconic St. Louis custard stand famous for thick concretes and nostalgic roadside charm. A must for trying the city’s best-known frozen treat.
A respected contemporary American restaurant known for refined cooking, strong wine service, and a polished neighborhood setting.
Generally moderate by U.S. standards. Hotels and attractions are often reasonable, while dining costs vary by neighborhood and venue.
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Los Angeles, CA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Los Angeles, CA to St. Louis, MO buses use the Los Angeles, Patsaouras Transit Plaza (Union Station) to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis, Lambert International Airport. Use this guide to compare Los Angeles, CA and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need