Knoxville, TN to Greenville, SC bus

Fri, Feb 06
+ Add return
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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Compare prices and tickets Knoxville, TN to Greenville, SC by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Bus from Knoxville, TN to Greenville, SC

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Buses from Knoxville, TN to Greenville, SC run on average 1 times per day, taking around 12h 0m. Cheap bus tickets for this journey start at $156 (€124) if you book in advance.

The earliest bus runs at 12:55, the last at 19:25. The fastest bus covers the 114 miles (185 km) distance in 12h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
114 miles (185 km)
Average bus duration
12h 0m
Cheapest ticket price
$156 (€124)
Buses per day
1
Fastest bus
12h 0m
First bus
12:55
Last bus
19:25
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Knoxville, TN to Greenville, SC

Find answers to the most common questions about traveling from Knoxville, TN to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Knoxville, TN to Greenville, SC can start from as little as $156 (€124) when you book in advance. The average bus ticket price for Knoxville, TN to Greenville, SC is $173 (€138) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Knoxville, TN to Greenville, SC is 12h 0m to travel the 114 miles (185 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Knoxville, TN to Greenville, SC leaves at 12:55 PM. Plan your trip with the Journey Planner from Omio.
The latest bus from Knoxville, TN to Greenville, SC leaves at 7:25 PM.
A trip to Greenville, SC from Knoxville, TN is worth doing but not as a day trip with a journey time of 12h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Knoxville, TN to Greenville, SC is October.
Yes, you can take a bus between Knoxville, TN and Greenville, SC.
No, the bus from Knoxville, TN to Greenville, SC has no accessibility options.
No, there are no bathrooms on board the bus from Knoxville, TN to Greenville, SC.
No, bikes are not allowed on board the bus from Knoxville, TN to Greenville, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Knoxville, TN to Greenville, SC.
No, luggage for the bus from Knoxville, TN to Greenville, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Knoxville, TN to Greenville, SC.
Unfortunately, pets are not allowed on the bus from Knoxville, TN to Greenville, SC.
No, there are no USB plugs on board the bus from Knoxville, TN to Greenville, SC.
No, there is no WiFi on board the bus from Knoxville, TN to Greenville, SC.

popular bus stations

Popular bus stations from Knoxville, TN to Greenville, SC

Knoxville
Greenville
The major bus station for departures in Knoxville is Knoxville, Kirkwood Street. Find all the information you need to know about services, amenities and connections at Knoxville, Kirkwood Street for your trip from Knoxville to Greenville.
Knoxville, Kirkwood Street
information

More options for your journey from Knoxville, TN to Greenville, SC

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Return journeys for buses from Greenville, SC to Knoxville, TN
Tickets and more information for coaches to Greenville, SC

Most popular buses to and from Greenville, SC and Knoxville, TN

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Bus Knoxville, TN - Indianapolis, IN
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Bus Boston, MA - Greenville, SC
Bus New York, NY - Greenville, SC
Bus Chicago, IL - Greenville, SC
Bus Washington, DC - Greenville, SC
Bus Philadelphia, PA - Greenville, SC
Bus Orlando, FL - Greenville, SC
Bus Atlanta, GA - Greenville, SC
Bus Miami, FL - Greenville, SC
Bus Houston, TX - Greenville, SC
Bus Sacramento, CA - Greenville, SC
Bus Tampa, FL - Greenville, SC
Bus Portland, OR - Greenville, SC
Bus Baltimore, MD - Greenville, SC
Bus Newark, NJ - Greenville, SC
Bus Charlotte, NC - Greenville, SC
Bus Nashville, TN - Greenville, SC
Bus Detroit, MI - Greenville, SC
Bus Minneapolis, MN - Greenville, SC
Bus Reno, NV - Greenville, SC
Bus Norfolk, VA - Greenville, SC
Bus Syracuse, NY - Greenville, SC
Bus West Palm Beach, FL - Greenville, SC
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