Knoxville, TN to Greenville, SC bus

Sun, Mar 22
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FlixBus
Alsa
Costa Verde
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
FlixBus
Alsa
Costa Verde
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
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Compare prices and tickets Knoxville, TN to Greenville, SC by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Bus from Knoxville, TN to Greenville, SC

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Take a bus from Knoxville, TN to Greenville, SC and enjoy the approximately 114 miles (185 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 12:55, the last at 19:25.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
114 miles (185 km)
Buses per day
1
First bus
12:55
Last bus
19:25
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Knoxville, TN to Greenville, SC

Find answers to the most common questions about traveling from Knoxville, TN to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from Knoxville, TN to Greenville, SC leaves at 12:55 PM. Plan your trip with the Journey Planner from Omio.
The latest bus from Knoxville, TN to Greenville, SC leaves at 7:25 PM.
The cheapest month for a bus from Knoxville, TN to Greenville, SC is October.
Yes, you can take a between Knoxville, TN and Greenville, SC.
No, the bus from Knoxville, TN to Greenville, SC has no accessibility options.
No, there are no bathrooms on board the bus from Knoxville, TN to Greenville, SC.
No, bikes are not allowed on board the bus from Knoxville, TN to Greenville, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Knoxville, TN to Greenville, SC.
No, luggage for the bus from Knoxville, TN to Greenville, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Knoxville, TN to Greenville, SC.
Unfortunately, pets are not allowed on the bus from Knoxville, TN to Greenville, SC.
No, there are no USB plugs on board the bus from Knoxville, TN to Greenville, SC.
No, there is no WiFi on board the bus from Knoxville, TN to Greenville, SC.

popular bus stations

Popular bus stations from Knoxville, TN to Greenville, SC

Knoxville
Greenville
The major bus station for departures in Knoxville is Knoxville, Kirkwood Street. Find all the information you need to know about services, amenities and connections at Knoxville, Kirkwood Street for your trip from Knoxville to Greenville.
Knoxville, Kirkwood Street
information

More options for your journey from Knoxville, TN to Greenville, SC

Here are some other resources that might have the information you need

Return journeys for buses from Greenville, SC to Knoxville, TN
Tickets and more information for coaches to Greenville, SC

Most popular buses to and from Greenville, SC and Knoxville, TN

Bus Knoxville, TN - New York, NY
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Bus Knoxville, TN - Washington, DC
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Bus Knoxville, TN - Atlanta, GA
Bus Knoxville, TN - Miami, FL
Bus Knoxville, TN - Tampa, FL
Bus Knoxville, TN - Baltimore, MD
Bus Knoxville, TN - Austin, TX
Bus Knoxville, TN - Nashville, TN
Bus Knoxville, TN - Raleigh, NC
Bus Knoxville, TN - Indianapolis, IN
Bus Knoxville, TN - Memphis, TN
Bus Boston, MA - Greenville, SC
Bus New York, NY - Greenville, SC
Bus Chicago, IL - Greenville, SC
Bus Washington, DC - Greenville, SC
Bus Philadelphia, PA - Greenville, SC
Bus Orlando, FL - Greenville, SC
Bus Atlanta, GA - Greenville, SC
Bus Miami, FL - Greenville, SC
Bus Houston, TX - Greenville, SC
Bus Sacramento, CA - Greenville, SC
Bus Tampa, FL - Greenville, SC
Bus Portland, OR - Greenville, SC
Bus Baltimore, MD - Greenville, SC
Bus Newark, NJ - Greenville, SC
Bus Austin, TX - Greenville, SC
Bus Charlotte, NC - Greenville, SC
Bus Detroit, MI - Greenville, SC
Bus Minneapolis, MN - Greenville, SC
Bus Reno, NV - Greenville, SC
Bus Syracuse, NY - Greenville, SC
Bus Norfolk, VA - Greenville, SC
Bus West Palm Beach, FL - Greenville, SC
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