Knoxville, TN to Greenville, SC bus

Fri, Nov 07
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
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Compare prices and tickets Knoxville, TN to Greenville, SC by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Nov 07
Sat
Nov 08
Sun
Nov 09
Mon
Nov 10
Tue
Nov 11
Wed
Nov 12
Thu
Nov 13

Journey information

Overview: Bus from Knoxville, TN to Greenville, SC

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Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
114 miles (185 km)
Average bus duration
11h 40m
Cheapest ticket price
$80 (€65)
Buses per day
1
Fastest bus
11h 40m
First bus
12:55
Last bus
14:45

Key Takeaways

Train Ticket Prices
  • Budget Options: Train tickets from Knoxville, TN to Greenville, SC start from as low as $80 (€65) if booked well in advance.
  • Standard Fares: Typically, trains cost $117 (€96) depending on the train type and class.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Knoxville, TN to Greenville, SC

Find answers to the most common questions about traveling from Knoxville, TN to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

FAQs
The first bus from Knoxville, TN to Greenville, SC leaves at 1: 25PM. Plan your trip with the Journey Planner   from Omio.
The last bus from Knoxville, TN to Greenville, SC leaves at 11: 45PM.
A day trip to Greenville, SC from Knoxville, TN is worth doing with a journey time of min each way. Check with Omio app   the best way to travel.
No, the bus from Knoxville, TN to Greenville, SC has no accessibility options.
No, there are no bathrooms on board the bus from Knoxville, TN to Greenville, SC.
No, bikes are not allowed on board the bus from Knoxville, TN to Greenville, SC.

To find the cheapest bus tickets for your trip from Knoxville, TN to Greenville, SC, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Knoxville, TN to Greenville, SC.
    No, luggage for the bus from Knoxville, TN to Greenville, SC needs to be booked in addition.
    No, there are no additional luggage options for the bus from Knoxville, TN to Greenville, SC.
    Unfortunately, pets are not allowed on the bus from Knoxville, TN to Greenville, SC.
    No, there are no USB plugs on board the bus from Knoxville, TN to Greenville, SC.
    No, there is no WiFi on board the bus from Knoxville, TN to Greenville, SC.

    popular bus stations

    Popular bus stations from Knoxville, TN to Greenville, SC

    Knoxville
    Greenville
    The major bus station for departures in Knoxville is Knoxville, Kirkwood Street. Find all the information you need to know about services, amenities and connections at Knoxville, Kirkwood Street for your trip from Knoxville to Greenville.
    Knoxville, Kirkwood Street
    information

    Most popular bus connections from Knoxville, TN

    Bus Knoxville, TN - Nashville, TN
    Bus Knoxville, TN - New York, NY

    More options for your journey from Knoxville, TN to Greenville, SC

    Here are some other resources that might have the information you need

    Return journeys for buses from Greenville, SC to Knoxville, TN
    Tickets and more information for coaches to Greenville, SC

    Most popular buses to and from Greenville, SC and Knoxville, TN

    Bus Knoxville, TN - New York, NY
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    Bus Boston, MA - Greenville, SC
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    Bus Chicago, IL - Greenville, SC
    Bus Washington, DC - Greenville, SC
    Bus Philadelphia, PA - Greenville, SC
    Bus Orlando, FL - Greenville, SC
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    Bus Miami, FL - Greenville, SC
    Bus Houston, TX - Greenville, SC
    Bus Sacramento, CA - Greenville, SC
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    Bus Portland, OR - Greenville, SC
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