Greenville, SC to Knoxville, TN bus

Fri, Nov 07
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
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Compare prices and tickets Greenville, SC to Knoxville, TN by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Nov 07
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Nov 08
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Nov 09
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Nov 10
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Nov 13

Journey information

Overview: Bus from Greenville, SC to Knoxville, TN

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Buses from Greenville, SC to Knoxville, TN run on average 1 times per day, taking around 7h 5m. Cheap bus tickets for this journey start at $48 (€39) if you book in advance.

The earliest bus runs at 19:05, the last at 23:45. The fastest bus covers the 114 miles (185 km) distance in 7h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
114 miles (185 km)
Average bus duration
7h 5m
Cheapest ticket price
$48 (€39)
Buses per day
1
Fastest bus
7h 5m
First bus
19:05
Last bus
23:45
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Greenville, SC to Knoxville, TN

Find answers to the most common questions about traveling from Greenville, SC to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Greenville, SC to Knoxville, TN can start from as little as $69 (€56) when you book in advance. The average bus ticket price for Greenville, SC to Knoxville, TN is $69 (€56); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Greenville, SC to Knoxville, TN bus time is 8 h 55 min   covering the 115 mile (185 km) long trip, but the journey time can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Greenville, SC to Knoxville, TN leaves at 6: 45PM. Plan your trip with the Journey Planner   from Omio.
The last bus from Greenville, SC to Knoxville, TN leaves at 11: 45PM.
The cheapest month for a bus from Greenville, SC to Knoxville, TN is November.
Yes, you can take a bus to Knoxville, TN from Greenville, SC.
No, the bus from Greenville, SC to Knoxville, TN has no accessibility options.
No, there are no bathrooms on board the bus from Greenville, SC to Knoxville, TN.
No, bikes are not allowed on board the bus from Greenville, SC to Knoxville, TN.

To find the cheapest bus tickets for your trip from Greenville, SC to Knoxville, TN, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Greenville, SC to Knoxville, TN.
    No, luggage for the bus from Greenville, SC to Knoxville, TN needs to be booked in addition.
    No, there are no additional luggage options for the bus from Greenville, SC to Knoxville, TN.
    Unfortunately, pets are not allowed on the bus from Greenville, SC to Knoxville, TN.
    No, there are no USB plugs on board the bus from Greenville, SC to Knoxville, TN.
    No, there is no WiFi on board the bus from Greenville, SC to Knoxville, TN.

    popular bus stations

    Popular bus stations from Greenville, SC to Knoxville, TN

    Greenville
    Knoxville
    The major bus station for departures in Greenville is Greenville, Woodruff Rd ("Raceway" gas station). Find all the information you need to know about services, amenities and connections at Greenville, Woodruff Rd ("Raceway" gas station) for your trip from Greenville to Knoxville.
    Greenville, Woodruff Rd ("Raceway" gas station)
    information

    More options for your journey from Greenville, SC to Knoxville, TN

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    Return journeys for buses from Knoxville, TN to Greenville, SC
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