4.9
4.6The cheapest and fastest buses from Greenville, SC to Knoxville, TN
Cheapest price
$86
Average price
$86
Fastest journey
7 h 5 m
Average duration
7 h 5 m
Buses per day
1
Distance
185 km
The best way to find a cheap bus ticket from Greenville, SC to Knoxville, TN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Knoxville, TN will cost around $86 if you buy it on the day, but the cheapest tickets can be found for only $86.
It's difficult to get from Greenville, SC to Knoxville, TN without transferring at least once.
· 2:45 PM7h05Greenville, Woodruff Rd ("Raceway" gas station), SC9:50 PMKnoxville, Kirkwood Street, TN$861One-way1 transfer
- · 2:45 PM7h05Greenville, Woodruff Rd ("Raceway" gas station), SC9:50 PMKnoxville, Kirkwood Street, TN$861One-way1 transfer
Travel Information
Compare bus for Greenville, SC to Knoxville, TN
Omio recommends booking the bus as it is the most popular option from Greenville, SC to Knoxville, TN among Omio's users. If you are prioritising price take the bus with prices starting from $95. For those with little time consider booking a bus which can get you there in 7h 5m. The ticket price range depends on the travel mode: a bus costs an average of $95, and a bus costs an average of $95.
Distance: 114 miles (185 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$95 Average price Cheapest | $34 Average price (fuel + tolls) |
7h 35m Average total duration Fastest 7h 5m Onboard + 30m Additional time* | 3h 0m Average total duration (door-to-door) |
Direct Options | Direct Options |
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Greenville, SC to Knoxville, TN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:45PM | Arrival Time 09:50PM | Duration 7h05 | Departure days Mon | Cheapest price $86 |
Operator Greyhound | Departure Time 07:45PM | Arrival Time 02:50AM | Duration 7h05 | Departure days Fri | Cheapest price $95 |
Compare prices and tickets Greenville, SC to Knoxville, TN by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Greenville, SC to Knoxville, TN
USAUSA
Buses from Greenville, SC to Knoxville, TN run on average 1 times per day, taking around 7h 5m. Cheap bus tickets for this journey start at $95 (€77) if you book in advance.
The earliest bus runs at 14:45, the last at 19:40. The fastest bus covers the 114 miles (185 km) distance in 7h 5m.
Distance 114 miles (185 km) |
Average bus duration 7h 5m |
Cheapest ticket price $95 (€77) |
Buses per day 1 |
Fastest bus 7h 5m |
First bus 2:45 PM |
Last bus 7:40 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jan - Mar |
FAQs: Bus from Greenville, SC to Knoxville, TN
Find answers to the most common questions about traveling from Greenville, SC to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.
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Popular bus stations from Greenville, SC to Knoxville, TN
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