Greenville, SC to Knoxville, TN bus

Fri, Feb 06
+ Add return
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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Compare prices and tickets Greenville, SC to Knoxville, TN by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Feb 06
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Journey information

Overview: Bus from Greenville, SC to Knoxville, TN

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Buses from Greenville, SC to Knoxville, TN run on average 1 times per day, taking around 7h 5m. Cheap bus tickets for this journey start at $96 (€76) if you book in advance.

The earliest bus runs at 14:45, the last at 19:40. The fastest bus covers the 114 miles (185 km) distance in 7h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
114 miles (185 km)
Average bus duration
7h 5m
Cheapest ticket price
$96 (€76)
Buses per day
1
Fastest bus
7h 5m
First bus
14:45
Last bus
19:40
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Greenville, SC to Knoxville, TN

Find answers to the most common questions about traveling from Greenville, SC to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Greenville, SC to Knoxville, TN can start from as little as $96 (€76) when you book in advance. The average bus ticket price for Greenville, SC to Knoxville, TN is $135 (€107) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Greenville, SC to Knoxville, TN is 7h 5m to travel the 114 miles (185 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Greenville, SC to Knoxville, TN leaves at 2:45 PM. Plan your trip with the Journey Planner from Omio.
The latest bus from Greenville, SC to Knoxville, TN leaves at 7:40 PM.
A trip to Knoxville, TN from Greenville, SC is worth doing but not as a day trip with a journey time of 7h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Greenville, SC to Knoxville, TN is September.
Yes, you can take a bus between Greenville, SC and Knoxville, TN.
No, the bus from Greenville, SC to Knoxville, TN has no accessibility options.
No, there are no bathrooms on board the bus from Greenville, SC to Knoxville, TN.
No, bikes are not allowed on board the bus from Greenville, SC to Knoxville, TN.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Greenville, SC to Knoxville, TN.
No, luggage for the bus from Greenville, SC to Knoxville, TN needs to be booked in addition.
No, there are no additional luggage options for the bus from Greenville, SC to Knoxville, TN.
Unfortunately, pets are not allowed on the bus from Greenville, SC to Knoxville, TN.
No, there are no USB plugs on board the bus from Greenville, SC to Knoxville, TN.
No, there is no WiFi on board the bus from Greenville, SC to Knoxville, TN.

popular bus stations

Popular bus stations from Greenville, SC to Knoxville, TN

Greenville
Knoxville
The major bus station for departures in Greenville is Greenville, Woodruff Rd ("Raceway" gas station). Find all the information you need to know about services, amenities and connections at Greenville, Woodruff Rd ("Raceway" gas station) for your trip from Greenville to Knoxville.
Greenville, Woodruff Rd ("Raceway" gas station)
information

More options for your journey from Greenville, SC to Knoxville, TN

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Return journeys for buses from Knoxville, TN to Greenville, SC
Tickets and more information for coaches to Greenville, SC

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