- Recommended
Greenville County Museum of Art
A major art museum in downtown Greenville with American art, Southern works, and rotating exhibitions in a bright riverfront setting.
Omio recommends booking the bus as it is the most popular option from Tallahassee, FL to Greenville, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €79 For those with little time, consider booking a bus, which has an average total journey time of 10h 51m. Average ticket prices depend on the travel mode: a bus costs an average of €79, while a bus costs an average of €79.
Distance: 324 miles (522 km)
Most popular Bus | Driving |
|---|---|
€79 Average price Cheapest | €62 Average price (fuel + tolls) |
10h 51m Average total duration Fastest 10h 21m Onboard + 30m Additional time* | 6h 33m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Tickets start at around €79 compared to roughly €62 in fuel and tolls — a saving of about €-17.01. The journey takes 10h 21m versus 6h 33m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:40PM | Arrival Time 03:15AM | Duration 9h35 | Departure days Thu, Fri, Sat | Cheapest price €53 |
The table below shows live departures for Tallahassee, FL to Greenville, SC buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 5:40 PM Tallahassee, C.K. Steele Plaza, FL | 9h35 | 3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Tallahassee, FL to Greenville, SC run on average 1 times per day, taking around 10h 21m. Cheap bus tickets for this journey start at €42 if you book in advance.
The earliest bus runs at 16:15, the last at 22:00. The fastest bus covers the 324 miles (522 km) distance in 8h 30m.
Distance 324 miles (522 km) |
Average bus duration 10h 21m |
Cheapest ticket price €42 |
Buses per day 1 |
Fastest bus 8h 30m |
First bus 4:15 PM |
Last bus 10:00 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Discover the best of Greenville, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville, SC trip today.
A major art museum in downtown Greenville with American art, Southern works, and rotating exhibitions in a bright riverfront setting.
A contemporary art center showing regional and international artists through rotating exhibitions in a modern downtown gallery space.
A local gallery and arts space featuring exhibitions, classes, and community-focused programming in Greenville's Village area.
A signature downtown park with waterfalls, gardens, river trails, and lawns. It is Greenville's most popular public space for walking and views.
Greenville's central street lined with shops, public art, and historic buildings. It is ideal for strolling between downtown attractions.
A swamp rabbit-themed riverside greenway popular for walking and cycling, linking downtown Greenville with parks and nearby districts.
Find answers to the most common questions about traveling from Tallahassee, FL to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

Most Tallahassee, FL to Greenville, SC buses use the to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Tallahassee, FL and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Limited dining options available in adjacent areas.
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
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