Why should you book Tallahassee, FL to Greenville, SC buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Tallahassee, FL to Greenville, SC
Buses from Tallahassee, FL to Greenville, SC run on average 4 times per day, taking around 13h 20m. Cheap bus tickets for this journey start at $106 (€86) if you book in advance.
The earliest bus runs at 16:15, the last at 22:00. The fastest bus covers the 324 miles (522 km) distance in 13h 20m.
Distance 324 miles (522 km) |
Average bus duration 13h 20m |
Cheapest ticket price $106 (€86) |
Buses per day 4 |
Fastest bus 13h 20m |
First bus 16:15 |
Last bus 22:00 |
Cheapest month Nov |
Cheapest day Sat |
High season Oct - Dec |
Low season Oct - Dec |
Bus providers: FlixBus from Tallahassee, FL to Greenville, SCYou can travel by bus between Tallahassee, FL to Greenville, SC with FlixBus for as low as $106 (€86). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Tallahassee, FL to Greenville, SC
Find answers to the most common questions about traveling from Tallahassee, FL to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Tallahassee, FL to Greenville, SC
More options for your journey from Tallahassee, FL to Greenville, SC
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