- Must visit
The Walters Art Museum
Major free art museum with collections spanning ancient, medieval, Renaissance, and Asian art in Mount Vernon.
Cheapest price
$81
Average price
$81
Fastest journey
12 h 45 m
Average duration
12 h 45 m
Buses per day
1
Distance
742 km
The best way to find a cheap bus ticket from Knoxville, TN to Baltimore, MD is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Knoxville, TN to Baltimore, MD will cost around $81 if you buy it on the day, but the cheapest tickets can be found for only $81.
Of the 1 buses that leave Knoxville, TN for Baltimore, MD on Mon, Jun 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 22 the direct buses cover the 742 km distance in an average of 12 h 45 m but if you time it right, some buses will get you there in just 12 h 45 m .
On Mon, Jun 22 the slowest buses will take 12 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Knoxville, TN to Baltimore, MD among Omio's users. If you are prioritising price take the bus with prices starting from $87. For those with little time consider booking a bus which can get you there in 12h 47m. The ticket price range depends on the travel mode: a bus costs an average of $87, and a bus costs an average of $87.
Distance: 461 miles (742 km)
Most popular Bus | Driving |
|---|---|
$111 Average price Cheapest | $15 Average price (fuel + tolls) |
13h 17m Average total duration Fastest 12h 47m Onboard + 30m Additional time* | 7h 47m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
You'll arrive about -5h 0m sooner (12h 47m by bus vs 7h 47m by car) and save roughly $-95.33 (€-78.02) compared to fuel and tolls ($111 (€91) vs $15 (€13)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Greyhound.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:50AM | Arrival Time 03:35PM | Duration 12h45 | Departure days Fri | Cheapest price $143 |
Operator Greyhound | Departure Time 10:50PM | Arrival Time 11:35AM | Duration 12h45 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $76 |
The table below shows live departures for Knoxville, TN to Baltimore, MD buses for today, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:50 PM Knoxville, Kirkwood Street, TN | 12h45 | 11:35 AM Baltimore, Haines St (Baltimore Downtown Bus Station) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Knoxville, TN to Baltimore, MD run on average 1 times per day, taking around 12h 47m. Cheap bus tickets for this journey start at $87 (€71) if you book in advance.
There are 1 buses per day. The earliest bus runs at 01:55, the last at 23:45. The fastest bus covers the 461 miles (742 km) distance in 12h 45m.
Distance 461 miles (742 km) |
Average bus duration 12h 47m |
Cheapest ticket price $87 (€71) |
Buses per day 1 |
Direct buses 1 |
Fastest bus 12h 45m |
First bus 1:55 AM |
Last bus 11:45 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Baltimore — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Baltimore trip today.
Major free art museum with collections spanning ancient, medieval, Renaissance, and Asian art in Mount Vernon.
Leading art museum known for its Cone Collection, contemporary works, and sculpture garden near Johns Hopkins.
Distinctive museum dedicated to self-taught artists, with imaginative exhibitions and a whimsical outdoor setting.
Baltimore's best-known waterfront district with promenades, harbor views, museums, and easy access to major attractions.
Historic waterfront neighborhood known for cobblestone streets, maritime character, and lively local atmosphere.
Popular hilltop park with one of the city's classic skyline and harbor viewpoints, especially photogenic at sunset.
Broiled or lightly fried cakes made with sweet blue crab meat and minimal filler. They are one of Baltimore’s signature foods and a classic Chesapeake Bay specialty.
Whole blue crabs steamed and coated with a bold spice blend, often eaten communally at crab houses. This is a defining Baltimore seafood tradition.
Baltimore barbecue specialty of charcoal-grilled roast beef sliced thin and served on a roll, often with raw onion and horseradish or tiger sauce.
Classic upscale steakhouse with old-school service, live music, and a refined atmosphere. A Baltimore institution for fine dining and cocktails.
Historic Lexington Market seafood counter famous for jumbo lump crab cakes. Casual, bustling, and one of the city’s most iconic food stops.
Popular local cafe known for elevated Chesapeake-inspired brunch dishes, crab specials, and friendly, lively service.
Moderate by U.S. standards. Hotels and dining vary by area; seafood and downtown spots cost more.
Tip 18-20% in restaurants; 20%+ for great service. USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Knoxville, TN to Baltimore, MD by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Baltimore, MD, this guide helps you travel smarter and with confidence.

Most Knoxville, TN to Baltimore, MD buses use the Knoxville, Kirkwood Street to Baltimore, Haines St (Baltimore Downtown Bus Station) station pair. Use this guide to compare Knoxville, TN and Baltimore, MD bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need