Why should you book Knoxville, TN to Baltimore, MD buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Knoxville, TN to Baltimore, MD.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu?
Journey information
Overview: Bus from Knoxville, TN to Baltimore, MD
Buses from Knoxville, TN to Baltimore, MD run on average 1 times per day, taking around 13h 10m. Cheap bus tickets for this journey start at $148 (€118) if you book in advance.
The earliest bus runs at 00:10, the last at 23:45. The fastest bus covers the 461 miles (742 km) distance in 12h 45m.
Distance 461 miles (742 km) |
Average bus duration 13h 10m |
Cheapest ticket price $148 (€118) |
Buses per day 1 |
Fastest bus 12h 45m |
First bus 00:10 |
Last bus 23:45 |
Bus providers: Greyhound from Knoxville, TN to Baltimore, MDYou can travel by bus between Knoxville, TN to Baltimore, MD with Greyhound for as low as $148 (€118). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Knoxville, TN to Baltimore, MD
Find answers to the most common questions about traveling from Knoxville, TN to Baltimore, MD by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Baltimore, MD, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Fort McHenry National Monument, a historic site known for its role in the War of 1812 and birthplace of the U.S. national anthem
- National Aquarium, a renowned facility featuring diverse marine life exhibits and conservation programs
- Baltimore Museum of Art, home to an extensive collection of 19th-century, modern, and contemporary art
- Inner Harbor, a vibrant waterfront area with shops, restaurants, and attractions like the Maryland Science Center
- American Visionary Art Museum, showcasing unique and innovative works by self-taught artists.
- Walk through Fell's Point, a charming historic district with cobblestone streets, pubs, and boutiques
- Enjoy a scenic stroll through Patterson Park, a large urban park offering beautiful views, walking trails, and a historic pagoda
- Attend a performance at the Hippodrome Theatre, a beautifully restored venue hosting Broadway shows and concerts
- Visit the Maryland Zoo, home to a wide variety of animals and engaging exhibits
- Explore the Walters Art Museum, featuring a diverse collection of art from around the world.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Knoxville, TN to Baltimore, MD
Most popular bus connections from Knoxville, TN
More options for your journey from Knoxville, TN to Baltimore, MD
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