- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price on Sep 18
CHF34
Average ticket price on Sep 18
CHF42
Fastest journey on Sep 18
8 h 5 m
Average journey duration on Sep 18
8 h 34 m
Buses on Sep 18
26
Distance
452 km
The best way to find a cheap bus ticket from Karlsruhe to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Prague will cost around CHF42 if you buy it on the day, but the cheapest tickets can be found for only CHF34.
On Fri, Sep 18, we found 26 buses from Karlsruhe to Prague, including 8 direct services.
On Fri, Sep 18 the direct buses cover the 452 km distance in an average of 8 h 34 m but if you time it right, some buses will get you there in just 8 h 5 m .
On Fri, Sep 18 the slowest buses will take 8 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus
FlixBus
FlixBus · FlixBus
FlixBusOmio recommends booking the train as it is the most popular option from Karlsruhe to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of CHF47 For those with little time, consider booking a train, which has an average total journey time of 8h 36m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of CHF47, while a train costs an average of CHF123.
Distance: 280 miles (452 km)
| Bus | Most popular Train | Driving |
|---|---|---|
CHF47 Average price Cheapest | CHF123 Average price | CHF95 Average price (fuel + tolls) |
9h 16m Average total duration 8h 46m Onboard + 30m Additional time* | 8h 36m Average total duration Fastest 8h 6m Onboard + 30m Additional time* | 5h 45m Average total duration (door-to-door) |
0.5 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Prague:
A bus is CHF76 less than a train for this route with tickets for a train from Karlsruhe to Prague costing on average CHF123.
Other travel options to Prague take longer:
Bus takes on average 8h 46m.
Tickets start at around CHF47 compared to roughly CHF95 in fuel and tolls — a saving of about CHF48. The journey takes 8h 46m versus 5h 45m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05AM | Arrival Time 10:35AM | Duration 10h30 | Departure days Everyday | Cheapest price CHF28 |
Operator FlixBus | Departure Time 01:55AM | Arrival Time 11:30AM | Duration 9h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price CHF28 |
Operator FlixBus | Departure Time 02:15AM | Arrival Time 12:10PM | Duration 9h55 | Departure days Everyday | Cheapest price CHF28 |
Operator FlixBus | Departure Time 03:05AM | Arrival Time 02:45PM | Duration 11h40 | Departure days Everyday | Cheapest price CHF29 |
Operator FlixBus | Departure Time 04:55AM | Arrival Time 02:35PM | Duration 9h40 | Departure days Everyday | Cheapest price CHF29 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 04:10PM | Duration 9h45 | Departure days Everyday | Cheapest price CHF27 |
Operator FlixBus | Departure Time 08:35AM | Arrival Time 05:30PM | Duration 8h55 | Departure days Everyday | Cheapest price CHF32 |
Operator BlaBlaCar | Departure Time 09:30AM | Arrival Time 03:30PM | Duration 6h00 | Departure days Thu | Cheapest price CHF35 |
Operator FlixBus | Departure Time 10:15AM | Arrival Time 08:20PM | Duration 10h05 | Departure days Everyday | Cheapest price CHF32 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 09:10PM | Duration 8h55 | Departure days Everyday | Cheapest price CHF28 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 10:45PM | Duration 10h15 | Departure days Sun | Cheapest price CHF36 |
Operator FlixBus | Departure Time 01:20PM | Arrival Time 12:45AM | Duration 11h25 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price CHF28 |
Operator FlixBus | Departure Time 02:23PM | Arrival Time 11:10PM | Duration 8h47 | Departure days Tue, Wed, Thu, Sat, Sun | Cheapest price CHF28 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 03:15AM | Duration 10h55 | Departure days Thu, Fri, Sat, Sun | Cheapest price CHF38 |
Operator AMI-Tour | Departure Time 05:45PM | Arrival Time 02:00AM | Duration 8h15 | Departure days Mon | Cheapest price CHF131 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 06:55AM | Duration 10h35 | Departure days Everyday | Cheapest price CHF28 |
Operator FlixBus | Departure Time 11:25PM | Arrival Time 08:55AM | Duration 9h30 | Departure days Everyday | Cheapest price CHF27 |
The table below shows live departures for Karlsruhe to Prague buses for today, Thursday, September 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 10:15 AM Karlsruhe Hbf | 10h05 | 8:20 PM Praha, Na Knížecí | 1 transfer | |
FlixBus | 12:15 PM Karlsruhe Hbf | 10h25 | 10:40 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 12:15 PM Karlsruhe Hbf | 11h40 | 11:55 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 12:15 PM Karlsruhe Hbf | 8h55 | 9:10 PM Praha, Na Knížecí | 1 transfer | |
FlixBus+ FlixTrain | 2:23 PM Karlsruhe Hbf | 8h32 | 10:55 PM Praha, Na Knížecí | 1 transfer | |
FlixBus+ FlixTrain | 2:23 PM Karlsruhe Hbf | 8h47 | 11:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 4:20 PM Karlsruhe Hbf | 10h55 | 3:15 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 8:20 PM Karlsruhe Hbf | 10h35 | 6:55 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 11:25 PM Karlsruhe Hbf | 11h10 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus | 11:25 PM Karlsruhe Hbf | 8h05 | 7:30 AM Praha, M. Horákové (Hradčanská) | 0 transfersDirect | |
FlixBus | 11:25 PM Karlsruhe Hbf | 8h25 | 7:50 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 11:25 PM Karlsruhe Hbf | 9h05 | 8:30 AM Praha, Zličín | 1 transfer | |
FlixBus · FlixBus | 11:25 PM Karlsruhe Hbf | 9h30 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
| Friday, September 18 | |||||
FlixBus · FlixBus | 12:05 AM Karlsruhe Hbf | 10h30 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 12:05 AM Karlsruhe Hbf | 10h40 | 10:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 1:55 AM Karlsruhe Hbf | 9h35 | 11:30 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 1:55 AM Karlsruhe Hbf | 9h25 | 11:20 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 2:15 AM Karlsruhe Hbf | 9h55 | 12:10 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 2:15 AM Karlsruhe Hbf | 10h10 | 12:25 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 3:05 AM Karlsruhe Hbf | 11h40 | 2:45 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 4:55 AM Karlsruhe Hbf | 9h40 | 2:35 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 6:25 AM Karlsruhe Hbf | 9h45 | 4:10 PM Praha, Černý Most | 0 transfersDirect | |
FlixBus | 6:25 AM Karlsruhe Hbf | 9h00 | 3:25 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 8:35 AM Karlsruhe Hbf | 8h55 | 5:30 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus | 8:35 AM Karlsruhe Hbf | 9h10 | 5:45 PM Praha, ÚAN Florenc | 0 transfersDirect | |
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Karlsruhe to Prague run on average 24 times per day, taking around 8h 46m. Cheap bus tickets for this journey start at CHF27 but you can travel from only CHF10 by train.
There are 8 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 280 miles (452 km) distance in 7h 10m.
Distance 280 miles (452 km) |
Average bus duration 8h 46m |
Cheapest ticket price CHF27 |
Buses per day 24 |
Direct buses 8 |
Fastest bus 7h 10m |
First bus 12:05 AM |
Last bus 11:50 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sat |
Best time to book 42 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Karlsruhe to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Karlsruhe to Prague buses use the Karlsruhe Hbf to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Hlavní Nádraží. Use this guide to compare Karlsruhe and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) is 1 km from Karlsruhe city centre. Public transport options include:
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang). ATMs are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Ticket office support is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): Parking, Taxis, WC.
Accessibility facilities are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): The station is accessible for passengers with reduced mobility.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Here are some other resources that might have the information you need