The cheapest and fastest buses from Karlsruhe to Prague
Cheapest price
$42
Average price
$56
Fastest journey
5 h
Average duration
8 h 29 m
Buses per day
14
Distance
452 km
The best way to find a cheap bus ticket from Karlsruhe to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Prague will cost around $56 if you buy it on the day, but the cheapest tickets can be found for only $42.
Of the 14 buses that leave Karlsruhe for Prague on Wed, Nov 05, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Nov 05 the direct buses cover the 452 km distance in an average of 8 h 29 m but if you time it right, some buses will get you there in just 5 h .
On Wed, Nov 05 the slowest buses will take 10 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus · FlixBus
FlixBus
FlixBusTravel Information
Compare bus and train for Karlsruhe to Prague
Omio recommends booking the train as it is the most popular option from Karlsruhe to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €26. For those with little time consider booking a bus which can get you there in 7h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €26, and a train costs an average of €28.
Distance: 280 miles (452 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€43 Average price Cheapest | €79 Average price |
7h 49m Average total duration Fastest 7h 19m Onboard + 30m Additional time* | 9h 25m Average total duration 8h 55m Onboard + 30m Additional time* |
0.5 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Karlsruhe to Prague Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05AM | Arrival Time 10:45AM | Duration 10h40 | Departure days Mon, Fri, Sat, Sun | Cheapest price $46 |
Operator FlixBus | Departure Time 02:25AM | Arrival Time 01:55PM | Duration 11h30 | Departure days Wed | Cheapest price $59 |
Operator FlixBus | Departure Time 03:05AM | Arrival Time 01:55PM | Duration 10h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $46 |
Operator FlixBus | Departure Time 04:55AM | Arrival Time 03:20PM | Duration 10h25 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $46 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 04:10PM | Duration 9h45 | Departure days Mon, Fri, Sat, Sun | Cheapest price $43 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 07:10PM | Duration 12h20 | Departure days Wed | Cheapest price $62 |
Operator FlixBus | Departure Time 08:35AM | Arrival Time 05:30PM | Duration 8h55 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $49 |
Operator FlixBus | Departure Time 10:15AM | Arrival Time 08:20PM | Duration 10h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $45 |
Operator FlixBus | Departure Time 11:23AM | Arrival Time 11:10PM | Duration 11h47 | Departure days Thu | Cheapest price $57 |
Operator FlixBus | Departure Time 11:45AM | Arrival Time 10:15PM | Duration 10h30 | Departure days Mon, Sat, Sun | Cheapest price $46 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 10:40PM | Duration 10h25 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $45 |
Operator FlixBus | Departure Time 01:20PM | Arrival Time 09:50PM | Duration 8h30 | Departure days Mon, Fri, Sat, Sun | Cheapest price $43 |
Operator BlaBlaCar | Departure Time 02:50PM | Arrival Time 08:00PM | Duration 5h10 | Departure days Thu | Cheapest price $59 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 03:15AM | Duration 11h00 | Departure days Fri, Sat | Cheapest price $55 |
Operator BlaBlaCar | Departure Time 06:00PM | Arrival Time 11:00PM | Duration 5h00 | Departure days Wed | Cheapest price $42 |
Operator FlixBus | Departure Time 06:20PM | Arrival Time 06:00AM | Duration 11h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $45 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 06:55AM | Duration 10h35 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $54 |
Operator BlaBlaCar | Departure Time 10:50PM | Arrival Time 05:00AM | Duration 6h10 | Departure days Mon | Cheapest price $38 |
Operator FlixBus | Departure Time 11:20PM | Arrival Time 10:35AM | Duration 11h15 | Departure days Wed | Cheapest price $53 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 08:30AM | Duration 9h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $39 |
Live departures
Karlsruhe to Prague bus times
The table below shows live departures for Karlsruhe to Prague buses for tomorrow, Wednesday, November 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 1:25 AM Karlsruhe Hbf | 11h30 | 12:55 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:25 AM Karlsruhe Hbf | 11h40 | 1:05 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 3:55 AM Karlsruhe Hbf | 10h25 | 2:20 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 3:55 AM Karlsruhe Hbf | 10h35 | 2:30 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 5:50 AM Karlsruhe Hbf | 12h20 | 6:10 PM Praha, Na Knížecí | 1 transfer | |
FlixBus | 7:35 AM Karlsruhe Hbf | 8h55 | 4:30 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus · FlixBus | 7:35 AM Karlsruhe Hbf | 11h45 | 7:20 PM Praha, Na Knížecí | 1 transfer | |
FlixBus | 7:35 AM Karlsruhe Hbf | 9h10 | 4:45 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 11:15 AM Karlsruhe Hbf | 8h55 | 8:10 PM Praha, Na Knížecí | 1 transfer | |
FlixBus | 11:15 AM Karlsruhe Hbf | 10h25 | 9:40 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 7:20 PM Karlsruhe Hbf | 10h35 | 5:55 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 10:20 PM Karlsruhe Hbf | 11h15 | 9:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 10:20 PM Karlsruhe Hbf | 11h25 | 9:45 AM Praha, ÚAN Florenc | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to Prague by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 05
Nov 06
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Nov 14
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Nov 18
Nov 19
Nov 20
Nov 21
Nov 22
Nov 23
Nov 24
Nov 25
Journey information
Overview: Bus from Karlsruhe to Prague
Distance 280 miles (452 km) |
Average bus duration 7h 19m |
Cheapest ticket price $32 (€26) |
Buses per day 25 |
Direct buses 8 |
Fastest bus 8h 10m |
First bus 00:05 |
Last bus 23:50 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Karlsruhe to Prague start from as low as $32 (€26) if booked well in advance.
- Standard Fares: Typically, trains cost $52 (€43) depending on the train type and class.
Bus providers: FlixBus, BlaBlaCar from Karlsruhe to PragueYou can travel by bus between Karlsruhe to Prague with FlixBus, BlaBlaCar for as low as $32 (€26). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
FAQs: Bus from Karlsruhe to Prague

Passengers board the bus most frequently from Karlsruhe Hbf, which is located around 1.7 miles (2.8 km) away from the city centre, and they get off the bus at Prague, Central Train Station, located 1.8 miles (2.9 km) away from the city centre.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Karlsruhe to Prague, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Karlsruhe to Prague
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- 00:00-23:59
- Free Wi-Fi
- Cafeteria Černý Most (in the station)
- Czech Bistro (in the station)
- Fast Food Express (in the station).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 177, 195, 201 Metro: B
- Bus: 131, 174, 180 Metro: A Train: S4, S5
Most popular bus connections from Karlsruhe
More options for your journey from Karlsruhe to Prague
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