- Must visit
National Museum
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
Cheapest price
$46
Average price
$55
Fastest journey
8 h 5 m
Average duration
8 h 34 m
Buses per day
26
Distance
452 km
The best way to find a cheap bus ticket from Karlsruhe to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Prague will cost around $55 if you buy it on the day, but the cheapest tickets can be found for only $46.
Of the 26 buses that leave Karlsruhe for Prague on Fri, Jun 19, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 19 the direct buses cover the 452 km distance in an average of 8 h 34 m but if you time it right, some buses will get you there in just 8 h 5 m .
On Fri, Jun 19 the slowest buses will take 8 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBusOmio recommends booking the train as it is the most popular option from Karlsruhe to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $31. For those with little time consider booking a bus which can get you there in 7h 29m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $31, and a train costs an average of $35.
Distance: 280 miles (452 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$49 Average price Cheapest | $78 Average price | $115 Average price (fuel + tolls) |
7h 59m Average total duration Fastest 7h 29m Onboard + 30m Additional time* | 9h 35m Average total duration 9h 5m Onboard + 30m Additional time* | 5h 45m Average total duration (door-to-door) |
0.5 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Prague:
A bus is $29 (€24) less than a train for this route with tickets for a train from Karlsruhe to Prague costing on average $78 (€64).
Other travel options to Prague take longer:
Train takes on average 9h 5m.
Tickets start at around $49 (€40) compared to roughly $115 (€94) in fuel and tolls — a saving of about $66 (€54). The journey takes 7h 29m versus 5h 45m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05AM | Arrival Time 10:45AM | Duration 10h40 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 01:55AM | Arrival Time 11:30AM | Duration 9h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $36 |
Operator FlixBus | Departure Time 02:15AM | Arrival Time 12:25PM | Duration 10h10 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 03:05AM | Arrival Time 02:45PM | Duration 11h40 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $35 |
Operator BlaBlaCar | Departure Time 03:20AM | Arrival Time 08:40AM | Duration 5h20 | Departure days Fri | Cheapest price $48 |
Operator FlixBus | Departure Time 04:55AM | Arrival Time 02:35PM | Duration 9h40 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 03:25PM | Duration 9h00 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $32 |
Operator FlixBus | Departure Time 08:35AM | Arrival Time 05:45PM | Duration 9h10 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $36 |
Operator FlixBus | Departure Time 10:15AM | Arrival Time 08:20PM | Duration 10h05 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $40 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 10:40PM | Duration 10h25 | Departure days Everyday | Cheapest price $35 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 10:45PM | Duration 10h15 | Departure days Sun | Cheapest price $56 |
Operator BlaBlaCar | Departure Time 01:20PM | Arrival Time 08:40PM | Duration 7h20 | Departure days Fri | Cheapest price $45 |
Operator FlixBus | Departure Time 01:20PM | Arrival Time 10:55PM | Duration 9h35 | Departure days Everyday | Cheapest price $32 |
Operator FlixBus | Departure Time 02:23PM | Arrival Time 11:10PM | Duration 8h47 | Departure days Sun | Cheapest price $52 |
Operator BlaBlaCar | Departure Time 03:50PM | Arrival Time 09:00PM | Duration 5h10 | Departure days Fri | Cheapest price $58 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 03:15AM | Duration 10h55 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $35 |
Operator Infobus | Departure Time 05:45PM | Arrival Time 02:00AM | Duration 8h15 | Departure days Mon | Cheapest price $159 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 06:55AM | Duration 10h35 | Departure days Everyday | Cheapest price $34 |
Operator BlaBlaCar | Departure Time 08:20PM | Arrival Time 02:10AM | Duration 5h50 | Departure days Fri | Cheapest price $50 |
Operator FlixBus | Departure Time 11:25PM | Arrival Time 08:55AM | Duration 9h30 | Departure days Everyday | Cheapest price $34 |
The table below shows live departures for Karlsruhe to Prague buses for today, Thursday, June 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:25 PM Karlsruhe Hbf | 9h30 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 11:25 PM Karlsruhe Hbf | 9h05 | 8:30 AM Praha, Zličín | 1 transfer | |
FlixBus | 11:25 PM Karlsruhe Hbf | 8h05 | 7:30 AM Praha, M. Horákové (Hradčanská) | 0 transfersDirect | |
FlixBus | 11:25 PM Karlsruhe Hbf | 8h25 | 7:50 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 11:25 PM Karlsruhe Hbf | 11h10 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 12:05 AM Karlsruhe Hbf | 10h40 | 10:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 12:05 AM Karlsruhe Hbf | 10h30 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:55 AM Karlsruhe Hbf | 9h25 | 11:20 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:55 AM Karlsruhe Hbf | 9h35 | 11:30 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 2:15 AM Karlsruhe Hbf | 10h10 | 12:25 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 2:15 AM Karlsruhe Hbf | 9h55 | 12:10 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 3:05 AM Karlsruhe Hbf | 11h40 | 2:45 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 4:55 AM Karlsruhe Hbf | 9h40 | 2:35 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 6:25 AM Karlsruhe Hbf | 9h45 | 4:10 PM Praha, Černý Most | 0 transfersDirect | |
FlixBus | 6:25 AM Karlsruhe Hbf | 9h00 | 3:25 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 8:35 AM Karlsruhe Hbf | 8h55 | 5:30 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus | 8:35 AM Karlsruhe Hbf | 9h10 | 5:45 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 10:15 AM Karlsruhe Hbf | 10h05 | 8:20 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 12:15 PM Karlsruhe Hbf | 8h55 | 9:10 PM Praha, Na Knížecí | 1 transfer | |
FlixBus | 12:15 PM Karlsruhe Hbf | 10h25 | 10:40 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 12:15 PM Karlsruhe Hbf | 11h40 | 11:55 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:20 PM Karlsruhe Hbf | 9h35 | 10:55 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 1:20 PM Karlsruhe Hbf | 11h05 | 12:25 AM Prague, Central Train Station | 1 transfer | |
FlixBus | 1:20 PM Karlsruhe Hbf | 8h30 | 9:50 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 4:20 PM Karlsruhe Hbf | 10h55 | 3:15 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 8:20 PM Karlsruhe Hbf | 10h35 | 6:55 AM Praha, ÚAN Florenc | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Karlsruhe to Prague run on average 24 times per day, taking around 7h 29m. Cheap bus tickets for this journey start at $31 (€25) if you book in advance.
There are 8 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 280 miles (452 km) distance in 8h 5m.
Distance 280 miles (452 km) |
Average bus duration 7h 29m |
Cheapest ticket price $31 (€25) |
Buses per day 24 |
Direct buses 8 |
Fastest bus 8h 5m |
First bus 12:05 AM |
Last bus 11:50 PM |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Wed |
Best time to book 63 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
A significant museum complex preserving Jewish history and heritage through synagogues, ceremonial objects, and exhibitions in Josefov.
A highly regarded design museum with glass, ceramics, fashion, graphics, and decorative arts in a historic building near the Old Town.
Prague’s ceremonial heart, surrounded by historic facades, churches, and major landmarks; essential for first-time visitors.
A picturesque historic district below Prague Castle with baroque streets, embassies, gardens, and a romantic atmosphere.
A major boulevard-like square central to modern Czech history, shopping, and public life, anchored by the National Museum.
Marinated beef sirloin with creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the best-known classic Czech festive dishes.
Roast pork served with dumplings and braised cabbage. This is a cornerstone of traditional Czech home-style cooking and pub menus.
Czech-style goulash is usually a rich beef stew with onions, paprika, and bread dumplings. It is a hearty staple often eaten in historic Prague pubs.
Established traditional restaurant known for duck, old-Bohemian recipes, and elegant historic interiors. A strong choice for a refined Czech meal.
Well-known Old Town restaurant offering polished Czech classics and seasonal dishes in a stylish but approachable atmosphere.
A famous modern Czech beer hall serving classic dishes, fresh Pilsner, and dependable traditional cooking in a lively central setting.
Moderate by European standards. Beer, transit, and casual meals are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. No tip needed for counter service, though small change is appreciated.
Official public transport app
Praha Hlavní Nádraží, Prague -> Václavské Náměstí, Prague
Find answers to the most common questions about traveling from Karlsruhe to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Karlsruhe to Prague buses use the Karlsruhe Hbf to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Karlsruhe and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Here are some other resources that might have the information you need