- Must visit
Pinacoteca di Brera
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
Cheapest price
€38
Average price
€48
Fastest journey
7 h 20 m
Average duration
8 h 6 m
Buses per day
6
Distance
398 km
The best way to find a cheap bus ticket from Karlsruhe to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Milan will cost around €48 if you buy it on the day, but the cheapest tickets can be found for only €38.
Of the 6 buses that leave Karlsruhe for Milan on Wed, Aug 26, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 26 the direct buses cover the 398 km distance in an average of 8 h 6 m but if you time it right, some buses will get you there in just 7 h 20 m .
On Wed, Aug 26 the slowest buses will take 8 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
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FlixBus
FlixBus
FlixBus
FlixBusOmio recommends booking the bus as it is the most popular option from Karlsruhe to Milan among Omio's users. If you are prioritising price take the bus with prices starting from €34. For those with little time consider booking a train which can get you there in 6h 27m. The ticket price range depends on the travel mode: a bus costs an average of €34, and a train costs an average of €54.
Distance: 247 miles (398 km)
Most popular Bus | Train | Driving |
|---|---|---|
€45 Average price Cheapest | €146 Average price | €144 Average price (fuel + tolls) |
10h 48m Average total duration 10h 18m Onboard + 30m Additional time* | 6h 57m Average total duration Fastest 6h 27m Onboard + 30m Additional time* | 6h 24m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Karlsruhe to Milan:
A bus is €100 less than a train for this route with tickets for a train from Karlsruhe to Milan costing on average €146.
Other travel options to Milan take longer:
Train takes on average 6h 27m.
Bus takes on average 10h 18m.
Tickets start at around €45 compared to roughly €144 in fuel and tolls — a saving of about €98. The journey takes 10h 18m versus 6h 24m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus, Marino Autolinee.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar Bus | Departure Time 12:25AM | Arrival Time 01:10PM | Duration 12h45 | Departure days Thu, Fri | Cheapest price €43 |
Operator FlixBus | Departure Time 03:20AM | Arrival Time 11:15AM | Duration 7h55 | Departure days Everyday | Cheapest price €41 |
Operator FlixBus | Departure Time 07:40AM | Arrival Time 05:50PM | Duration 10h10 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price €39 |
Operator Marino Autolinee | Departure Time 09:30AM | Arrival Time 08:40PM | Duration 11h10 | Departure days Thu, Sat | Cheapest price €60 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 04:50PM | Duration 7h20 | Departure days Everyday | Cheapest price €36 |
Operator FlixBus | Departure Time 11:05AM | Arrival Time 07:15PM | Duration 8h10 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price €38 |
Operator BlaBlaCar Bus | Departure Time 11:15AM | Arrival Time 06:00AM | Duration 18h45 | Departure days Sun | Cheapest price €75 |
Operator FlixBus | Departure Time 07:29PM | Arrival Time 04:50AM | Duration 9h21 | Departure days Fri, Sun | Cheapest price €92 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 05:05AM | Duration 8h55 | Departure days Everyday | Cheapest price €46 |
Operator BlaBlaCar Bus | Departure Time 09:05PM | Arrival Time 02:05PM | Duration 17h00 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price €62 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 07:10AM | Duration 8h10 | Departure days Everyday | Cheapest price €49 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 08:05AM | Duration 8h25 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €57 |
The table below shows live departures for Karlsruhe to Milan buses for today, Tuesday, August 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 3:20 AM Karlsruhe Hbf | 7h55 | 11:15 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 7:40 AM Karlsruhe Hbf | 10h10 | 5:50 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 9:30 AM Karlsruhe Hbf | 7h20 | 4:50 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 11:05 AM Karlsruhe Hbf | 8h10 | 7:15 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 8:10 PM Karlsruhe Hbf | 8h55 | 5:05 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
51510 · 4767 | 9:05 PM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 17h00 | 2:05 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus | 11:00 PM Karlsruhe Hbf | 8h10 | 7:10 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Karlsruhe to Milan run on average 8 times per day, taking around 10h 18m. Cheap bus tickets for this journey start at €34 if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 247 miles (398 km) distance in 7h 20m.
Distance 247 miles (398 km) |
Average bus duration 10h 18m |
Cheapest ticket price €34 |
Buses per day 8 |
Direct buses 6 |
Fastest bus 7h 20m |
First bus 12:15 AM |
Last bus 11:55 PM |
Cheapest Month Dec |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Thu |
Best time to book 14 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
This contemporary art museum near Porta Romana presents rotating exhibitions in a striking former industrial distillery complex.
Italy’s leading science museum is set in a former monastery and features Leonardo galleries, trains, aircraft, and a submarine.
Milan’s central square frames the cathedral and major civic buildings, making it the city’s essential meeting point and photo stop.
This artistic district offers charming lanes, Brera atmosphere, boutiques, and easy access to galleries and evening strolls.
A large landscaped park behind the castle, perfect for walks, skyline views, and reaching landmarks like the Arch of Peace.
Saffron risotto cooked with butter, stock and cheese. It is Milan's signature dish, linked to the city's love of rich northern Italian rice cookery.
Breaded veal cutlet fried in butter until golden. A classic Milanese main, prized for its simple preparation and long-standing local tradition.
Slow-braised veal shanks with vegetables, wine and broth, often finished with gremolata. A hearty Lombard specialty commonly paired with risotto.
Three-Michelin-star fine dining by Enrico Bartolini in MUDEC. Expect refined Italian tasting menus in a polished contemporary setting.
Historic Milanese restaurant near the Duomo, famous for risotto and cotoletta. Traditional, elegant rooms and a strong local culinary identity.
Long-running local favorite for classic Milanese cuisine, especially risotto and ossobuco. Warm, old-school atmosphere in the Brera area.
Moderate for Western Europe. Hotels and central dining can be pricey, but transit is affordable and budget meals, aperitivo deals, and local cafes help keep daily costs reasonable.
Tipping is modest. Service may be included. Round up or leave €1-2 at cafes, 5-10% for good restaurant service, and round up taxi fares.
Official public transport app
Orio al Serio, Milan Bergamo Airport (Bus station) -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Karlsruhe to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

Most Karlsruhe to Milan buses use the Karlsruhe Hbf to Milano, Autostazione Lampugnano station pair, with some services arriving at Milano, San Donato - Settore B (Viale Giuseppe Impastato). Use this guide to compare Karlsruhe and Milan bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) is 1 km from Karlsruhe city centre. Public transport options include:
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang). ATMs are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Ticket office support is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): Parking, Taxis, WC.
Accessibility facilities are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): The station is accessible for passengers with reduced mobility.
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Milano, Autostazione Lampugnano.
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
Milano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple fast food and dining options available.
Free Wi-Fi available for 30 minutes. ATMs are aTMs available in the main hall.
Ticket office support is available at Milano.
Available at Milano: Parking, Taxis, WC.
Accessibility facilities are available at Milano: Wheelchair accessible facilities available.
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