- Must visit
Pinacoteca di Brera
One of Italy’s leading art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the elegant Brera district.
Cheapest price
$59
Average price
$64
Fastest journey
7 h 20 m
Average duration
8 h 6 m
Buses per day
6
Distance
398 km
The best way to find a cheap bus ticket from Karlsruhe to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Milan will cost around $64 if you buy it on the day, but the cheapest tickets can be found for only $59.
Of the 6 buses that leave Karlsruhe for Milan on Wed, May 27, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, May 27 the direct buses cover the 398 km distance in an average of 8 h 6 m but if you time it right, some buses will get you there in just 7 h 20 m .
On Wed, May 27 the slowest buses will take 8 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus
54153 · 4751
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
FlixBusOmio recommends booking the train as it is the most popular option from Karlsruhe to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a train which can get you there in 6h 26m. The ticket price range depends on the travel mode: a bus costs an average of $24, and a train costs an average of $67.
Distance: 247 miles (398 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$55 Average price Cheapest | $171 Average price | $176 Average price (fuel + tolls) |
11h 10m Average total duration 10h 40m Onboard + 30m Additional time* | 6h 56m Average total duration Fastest 6h 26m Onboard + 30m Additional time* | 6h 24m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Karlsruhe to Milan:
A bus is $117 (€94) less than a train for this route with tickets for a train from Karlsruhe to Milan costing on average $171 (€138).
Other travel options to Milan take longer:
Train takes on average 6h 26m.
Bus takes on average 10h 40m.
Tickets start at around $55 (€44) compared to roughly $176 (€142) in fuel and tolls — a saving of about $122 (€98). The journey takes 10h 40m versus 6h 24m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus, Marino Autolinee.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar Bus | Departure Time 12:25AM | Arrival Time 09:25PM | Duration 21h00 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $92 |
Operator FlixBus | Departure Time 03:20AM | Arrival Time 11:15AM | Duration 7h55 | Departure days Everyday | Cheapest price $54 |
Operator FlixBus | Departure Time 07:40AM | Arrival Time 05:25PM | Duration 9h45 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $57 |
Operator Marino Autolinee | Departure Time 09:30AM | Arrival Time 08:40PM | Duration 11h10 | Departure days Thu, Sat | Cheapest price $57 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 04:50PM | Duration 7h20 | Departure days Everyday | Cheapest price $48 |
Operator FlixBus | Departure Time 11:05AM | Arrival Time 07:15PM | Duration 8h10 | Departure days Everyday | Cheapest price $51 |
Operator BlaBlaCar Bus | Departure Time 11:15AM | Arrival Time 06:00AM | Duration 18h45 | Departure days Wed, Fri, Sun | Cheapest price $66 |
Operator FlixBus | Departure Time 07:29PM | Arrival Time 04:50AM | Duration 9h21 | Departure days Fri, Sun | Cheapest price $74 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 05:05AM | Duration 8h55 | Departure days Everyday | Cheapest price $59 |
Operator BlaBlaCar Bus | Departure Time 09:05PM | Arrival Time 02:05PM | Duration 17h00 | Departure days Thu, Fri, Sat, Sun | Cheapest price $45 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 07:10AM | Duration 8h10 | Departure days Everyday | Cheapest price $61 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 08:05AM | Duration 8h25 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $51 |
The table below shows live departures for Karlsruhe to Milan buses for today, Tuesday, May 26. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 11:00 PM Karlsruhe Hbf | 8h10 | 7:10 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
| Wednesday, May 27 | |||||
FlixBus | 3:20 AM Karlsruhe Hbf | 7h55 | 11:15 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 9:30 AM Karlsruhe Hbf | 7h20 | 4:50 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 11:05 AM Karlsruhe Hbf | 8h10 | 7:15 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
54153 · 4751 | 11:15 AM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 18h45 | 6:00 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus | 8:10 PM Karlsruhe Hbf | 8h55 | 5:05 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Karlsruhe to Milan run on average 8 times per day, taking around 10h 40m. Cheap bus tickets for this journey start at $24 (€19) if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 247 miles (398 km) distance in 7h 20m.
Distance 247 miles (398 km) |
Average bus duration 10h 40m |
Cheapest ticket price $24 (€19) |
Buses per day 8 |
Direct buses 6 |
Fastest bus 7h 20m |
First bus 12:15 AM |
Last bus 11:55 PM |
Cheapest Month Dec |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 14 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
One of Italy’s leading art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the elegant Brera district.
A major museum of 20th-century Italian art facing Piazza del Duomo, with strong Futurist holdings and striking city views.
A contemporary museum focused on world cultures and major temporary exhibitions, popular for its modern architecture and changing shows.
Milan’s canal district, best known for waterside walks, photogenic bridges, and lively atmosphere day and night.
A charming historic neighborhood of narrow streets, galleries, boutiques, and classic Milan character, ideal for wandering.
Milan’s main square and the symbolic heart of the city, surrounded by major landmarks and constant urban energy.
Creamy saffron risotto, one of Milan's signature dishes, prized for its rich flavor and golden color.
Braised veal shank cooked slowly until tender, traditionally served with gremolata and often paired with risotto.
Breaded veal cutlet fried in butter, a classic Milanese specialty and one of the city's most famous dishes.
Celebrated fine dining restaurant offering creative haute cuisine with an elegant, Michelin-starred reputation.
Famous central bakery known for panzerotti, a beloved casual stop near the Duomo with constant local appeal.
Modern Milanese restaurant known for refined Lombard classics in a stylish contemporary setting.
Milan is pricier than most Italian cities, especially for hotels, central dining, and aperitivo areas.
Service is often included or covered by coperto. Tipping is not required, but rounding up or leaving EUR 1-5 for good service is appreciated. Taxis can be rounded up.
Official public transport app
Milan Linate Airport, Milan -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Karlsruhe to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

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