- Must visit
Museo del Prado
World-class art museum with masterpieces by Velázquez, Goya, and Bosch; essential for Spanish and European painting.
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Cheapest price
$230
Average price
$292
Fastest journey
31h 30m
Average duration
35h 2m
Buses per day
4
Distance
1348 km
Omio recommends booking the bus as it is the most popular option from Karlsruhe to Madrid among Omio's users. If you are prioritising price take the bus with prices starting from $60. For those with little time consider booking a train which can get you there in 12h 28m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.3 - 3.4kg. The ticket price range depends on the travel mode: a bus costs an average of $60, and a train costs an average of $569.
Distance: 837 miles (1348 km)
Most popular Bus | Train | Driving |
|---|---|---|
$111 Average price Cheapest | $569 Average price | $472 Average price (fuel + tolls) |
26h 14m Average total duration 25h 44m Onboard + 30m Additional time* | 12h 58m Average total duration Fastest 12h 28m Onboard + 30m Additional time* | 17h 48m Average total duration (door-to-door) |
1.3 - 3.4kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Madrid:
A bus is $458 (€375) less than a train for this route with tickets for a train from Karlsruhe to Madrid costing on average $569 (€466).
Other travel options to Madrid take longer:
Bus takes on average 25h 44m.
Tickets start at around $111 (€91) compared to roughly $472 (€386) in fuel and tolls — a saving of about $361 (€296). The journey takes 25h 44m versus 17h 48m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by BlaBlaCar Bus, Alsa.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:35AM | Arrival Time 07:55AM | Duration 31h20 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $166 |
Operator FlixBus | Departure Time 12:55AM | Arrival Time 07:25AM | Duration 30h30 | Departure days Wed, Fri, Sat, Sun | Cheapest price $180 |
Operator FlixBus | Departure Time 04:05AM | Arrival Time 08:40AM | Duration 28h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $107 |
Operator FlixBus | Departure Time 06:35AM | Arrival Time 08:10AM | Duration 25h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $139 |
Operator FlixBus | Departure Time 07:25AM | Arrival Time 11:30AM | Duration 28h05 | Departure days Wed | Cheapest price $134 |
Operator FlixBus | Departure Time 08:10AM | Arrival Time 11:30AM | Duration 27h20 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $146 |
Operator FlixBus | Departure Time 11:00AM | Arrival Time 01:20PM | Duration 26h20 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $118 |
Operator BlaBlaCar Bus | Departure Time 11:15AM | Arrival Time 02:05PM | Duration 26h50 | Departure days Wed, Fri, Sun | Cheapest price $92 |
Operator Alsa | Departure Time 11:15AM | Arrival Time 02:05PM | Duration 26h50 | Departure days Wed, Fri | Cheapest price $98 |
Operator FlixBus | Departure Time 02:23PM | Arrival Time 07:25AM | Duration 41h02 | Departure days Thu | Cheapest price $341 |
Operator FlixBus | Departure Time 07:29PM | Arrival Time 07:25AM | Duration 35h56 | Departure days Fri, Sun | Cheapest price $173 |
Operator BlaBlaCar Bus | Departure Time 09:05PM | Arrival Time 12:40AM | Duration 27h35 | Departure days Mon, Sat, Sun | Cheapest price $183 |
Operator FlixBus | Departure Time 11:10PM | Arrival Time 07:55AM | Duration 32h45 | Departure days Everyday | Cheapest price $136 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 10:30AM | Duration 34h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $153 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 07:25AM | Duration 31h30 | Departure days Everyday | Cheapest price $153 |
The table below shows live departures for Karlsruhe to Madrid buses for today, Thursday, July 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixTrain+ FlixBus · FlixBus · FlixBus | 2:23 PM Karlsruhe Hbf | 41h02 | 7:25 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 3 transfers | |
FlixBus · FlixBus | 11:10 PM Karlsruhe Hbf | 32h45 | 7:55 AM Madrid, Estación Sur de Autobuses | 1 transfer | |
FlixBus · FlixBus | 11:40 PM Karlsruhe Hbf | 34h50 | 10:30 AM Madrid, Estación Sur de Autobuses | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:55 PM Karlsruhe Hbf | 31h30 | 7:25 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 2 transfers | |
| Friday, July 17 | |||||
FlixBus · FlixBus · FlixBus | 12:35 AM Karlsruhe Hbf | 31h20 | 7:55 AM Madrid, Estación Sur de Autobuses | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:55 AM Karlsruhe Hbf | 30h30 | 7:25 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 2 transfers | |
FlixBus · FlixBus | 4:05 AM Karlsruhe Hbf | 28h35 | 8:40 AM Madrid, Estación Sur de Autobuses | 1 transfer | |
FlixBus · FlixBus | 6:35 AM Karlsruhe Hbf | 26h20 | 8:55 AM Madrid, Estación Sur de Autobuses | 1 transfer | |
FlixBus · FlixBus | 6:35 AM Karlsruhe Hbf | 25h35 | 8:10 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 6:35 AM Karlsruhe Hbf | 27h40 | 10:15 AM Madrid, Estación Sur de Autobuses | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:10 AM Karlsruhe Hbf | 27h20 | 11:30 AM Madrid, Estación Sur de Autobuses | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:00 AM Karlsruhe Hbf | 27h55 | 2:55 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 2 transfers | |
FlixBus · FlixBus | 11:00 AM Karlsruhe Hbf | 26h20 | 1:20 PM Madrid, Estación Sur de Autobuses | 1 transfer | |
54153 | 11:15 AM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 26h50 | 2:05 PM Madrid, Estación Sur de Autobuses | 0 transfersDirect | |
Normal | 11:15 AM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 26h50 | 2:05 PM Madrid, Estación Sur de Autobuses | 0 transfersDirect | |
Normal | 11:15 AM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 26h15 | 1:30 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Karlsruhe to Madrid run on average 8 times per day, taking around 25h 44m. Cheap bus tickets for this journey start at $60 (€49) if you book in advance.
The earliest bus runs at 00:35, the last at 23:55. The fastest bus covers the 837 miles (1348 km) distance in 26h 15m.
Distance 837 miles (1348 km) |
Average bus duration 25h 44m |
Cheapest ticket price $60 (€49) |
Buses per day 8 |
Fastest bus 26h 15m |
First bus 12:35 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Mon |
Best time to book 28 days |
Discover the best of Madrid — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Madrid trip today.
World-class art museum with masterpieces by Velázquez, Goya, and Bosch; essential for Spanish and European painting.
Leading modern art museum best known for Picasso’s Guernica, plus major works by Dalí and Miró.
Celebrated collection of European masters from Van Eyck to Hopper in a refined palace setting.
Madrid’s most famous park offers gardens, a boating lake, monuments, and relaxed walks in the city center.
Lively grand avenue known for architecture, shopping, theaters, and nonstop energy from day to night.
Elegant boulevard linking major museums and landmarks, ideal for a classic central Madrid walk.
A hearty chickpea stew with meats, vegetables, and broth, especially traditional in Madrid and often served in stages.
Crisp fried squid rings served in a baguette roll. This iconic Madrid street food is especially linked to bars around Plaza Mayor.
Tripe stew with chorizo and morcilla in a rich sauce. A classic old Madrid tavern dish with deep local roots.
Refined two-Michelin-star dining focused on seasonal Spanish produce, with elegant modern cooking in a polished fine-dining room.
Traditional Madrid restaurant known for cocido madrileño served in stages, with an old-school dining room and loyal local following.
Historic century-old tavern famed for roast suckling pig and Castilian dishes in a classic, wood-lined setting near Plaza Mayor.
Moderate for Western Europe: hotels vary, dining is reasonable, and public transport is good value for tourists.
Tipping is modest: round up or leave 5-10% in restaurants for good service. Taxis are usually rounded up. In cafés, small change is enough.
Official public transport app
Madrid Estación Sur de Autobuses -> Puerta del Sol
Find answers to the most common questions about traveling from Karlsruhe to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

Most Karlsruhe to Madrid buses use the Karlsruhe Hbf to Madrid, Estación Sur de Autobuses station pair, with some services arriving at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid). Use this guide to compare Karlsruhe and Madrid bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Madrid, Estación Sur de Autobuses is 3 km from Madrid city centre. Public transport options include:
Madrid, Estación Sur de Autobuses has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafetería de la estación (in the station), Restaurante El Brillante (0.5 km), La Taberna de Domínguez (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Madrid, Estación Sur de Autobuses.
Available at Madrid, Estación Sur de Autobuses: Parking, Taxis, WC.
Accessibility facilities are available at Madrid, Estación Sur de Autobuses: Elevators, ramps.
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) is 12 km from Madrid city centre. Public transport options include:
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) has practical services for this route, including Dining, ATM, Accessibility, WC, Shower, and Ticket Office.
Food options include: Rodilla, Mahoudrid
ATMs are aTMs located throughout T4, major cards accepted .
Ticket office support is available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid).
Available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): WC.
Accessibility facilities are available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): Step-free access, elevators, accessible toilets.
Here are some other resources that might have the information you need